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AR020717A1 - THERAPEUTICALLY ACTIVE PROTEINS IN PLANTS. - Google Patents

THERAPEUTICALLY ACTIVE PROTEINS IN PLANTS.

Info

Publication number
AR020717A1
AR020717A1 ARP990105036A ARP990105036A AR020717A1 AR 020717 A1 AR020717 A1 AR 020717A1 AR P990105036 A ARP990105036 A AR P990105036A AR P990105036 A ARP990105036 A AR P990105036A AR 020717 A1 AR020717 A1 AR 020717A1
Authority
AR
Argentina
Prior art keywords
plants
therapeutically active
active proteins
host
transgenic plants
Prior art date
Application number
ARP990105036A
Other languages
Spanish (es)
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Publication of AR020717A1 publication Critical patent/AR020717A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H5/00—Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8214—Plastid transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Environmental Sciences (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Pain & Pain Management (AREA)

Abstract

Plantas transgénicas que expresan proteínas terapéuticamente activas, de preferencia a partir de su genoma de plástido, o dirigidas hacia la vacuola. Laadministracion de estas plantas transgénicas a un hospedero que lo necesite, para la prevencion oel tratamiento de enfermedades. En una modalidad preferida,estas plantas o materia derivada a partir de estas plantas, se administran oralmente a un hospedero. Metodo de transformacion, vector y producto alimenticio.Transgenic plants that express therapeutically active proteins, preferably from their plastid genome, or directed towards the vacuole. The administration of these transgenic plants to a host that needs it, for the prevention or treatment of diseases. In a preferred embodiment, these plants or matter derived from these plants are administered orally to a host. Method of transformation, vector and food product.

ARP990105036A 1998-10-07 1999-10-05 THERAPEUTICALLY ACTIVE PROTEINS IN PLANTS. AR020717A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16736298A 1998-10-07 1998-10-07
US16823198A 1998-10-07 1998-10-07

Publications (1)

Publication Number Publication Date
AR020717A1 true AR020717A1 (en) 2002-05-22

Family

ID=26863095

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990105036A AR020717A1 (en) 1998-10-07 1999-10-05 THERAPEUTICALLY ACTIVE PROTEINS IN PLANTS.

Country Status (14)

Country Link
EP (1) EP1117817A2 (en)
JP (1) JP2002526116A (en)
KR (1) KR20010085901A (en)
CN (1) CN1330718A (en)
AR (1) AR020717A1 (en)
AU (2) AU758817B2 (en)
BR (1) BR9915919A (en)
CA (1) CA2344269A1 (en)
HU (1) HUP0103616A3 (en)
IL (1) IL142041A0 (en)
PL (1) PL347904A1 (en)
RU (2) RU2001111881A (en)
TR (1) TR200101032T2 (en)
WO (1) WO2000020612A2 (en)

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US7572466B1 (en) 1999-10-13 2009-08-11 Health Research, Inc. Oral immunology using plant product containing a non-enteric pathogen antigen
AU2001245358A1 (en) * 2000-02-29 2001-09-12 Auburn University Production of antibodies in transgenic plastids
AU2001252246A1 (en) * 2000-04-05 2001-10-23 Syngenta Participations Ag Therapeutically active proteins in plants
FR2809413B1 (en) * 2000-05-29 2004-10-22 Tabacs & Allumettes Ind PRODUCTION OF RECOMBINANT ALLERGENS IN PLANT CELLS
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GB2364705A (en) * 2000-07-14 2002-02-06 Icgeb Fusion protein expression in plastids
EP2290090A1 (en) 2000-08-11 2011-03-02 Syngenta Participations AG Methods for stable transformation of plants
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JP2005537784A (en) * 2002-04-23 2005-12-15 ザ スクリップス リサーチ インスティテュート Expression of polypeptides in chloroplasts and compositions and methods for expressing the polypeptides
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AU2003282502A1 (en) 2002-10-15 2004-05-04 Syngenta Participations Ag Plastid transformation
EP1594956A4 (en) 2003-02-03 2007-08-01 Fraunhofer Usa Inc SYSTEM FOR GENE EXPRESSION IN PLANTS
EP1597372A2 (en) * 2003-02-18 2005-11-23 Syngeta Participations AG Expression in plants of antibodies against enterotoxigenic escherichia coli
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US7951557B2 (en) 2003-04-27 2011-05-31 Protalix Ltd. Human lysosomal proteins from plant cell culture
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RU2259846C1 (en) * 2004-06-10 2005-09-10 Федоскова Татьяна Германовна Method and means for carrying out specific immunotherapy of allergic disease patients having sensitization to gnat stings
US8455717B2 (en) 2004-09-29 2013-06-04 Collplant Ltd. Collagen producing plants and methods of generating and using same
AU2012241058B2 (en) * 2005-07-18 2014-04-17 Protalix Ltd. Mucosal or Enteral Administration of Biologically Active Macromolecules
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BRPI0614475B8 (en) 2005-08-03 2021-05-25 Fraunhofer Usa Inc polypeptide, antibody, nucleic acid, vectors, host cell, antibody composition and production processes
AU2007215080A1 (en) 2006-02-13 2007-08-23 Fraunhofer Usa, Inc. Influenza antigens, vaccine compositions, and related methods
GB0604938D0 (en) 2006-03-11 2006-04-19 Renovo Ltd Proteins, nucleic acids and medicaments
GB0604964D0 (en) 2006-03-11 2006-04-19 Renovo Ltd Protein folding
GB0604966D0 (en) 2006-03-11 2006-04-19 Renovo Ltd Medicaments and proteins
GB0617816D0 (en) * 2006-09-11 2006-10-18 Renovo Ltd Nucleic acids and methods of protein expression
WO2008135991A2 (en) 2007-05-07 2008-11-13 Protalix Ltd. Large scale disposable bioreactor
GB2449466B (en) * 2007-05-23 2009-11-18 Algentech Ltd Production of proteins in plant tissue
CA2692933C (en) 2007-07-11 2016-10-18 Fraunhofer Usa, Inc. Yersinia pestis antigens, vaccine compositions, and related methods
BRPI0818268A2 (en) * 2007-10-31 2017-05-09 Univ Central Florida Res Found Inc chloroplast-derived human vaccine antigens against malaria
CA2729382A1 (en) * 2008-06-30 2010-01-07 Bjorn Larus Orvar Use of plant-derived recombinant growth factors in skin care
US8734803B2 (en) 2008-09-28 2014-05-27 Ibio Inc. Humanized neuraminidase antibody and methods of use thereof
US9175300B2 (en) 2008-11-27 2015-11-03 Vanga Siva Reddy Method of expressing foreign protein in plastids
US9551005B2 (en) * 2009-07-16 2017-01-24 Kenneth John Piller Immunoassay for detecting thyroglobulin utilizing soybean produced recombinant thyroglobulin
WO2011041391A1 (en) 2009-09-29 2011-04-07 Fraunhofer Usa, Inc. Influenza hemagglutinin antibodies, compositions, and related methods
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Also Published As

Publication number Publication date
AU2003200126A1 (en) 2003-04-17
RU2001111881A (en) 2003-06-20
AU2003200126A9 (en) 2003-04-17
IL142041A0 (en) 2002-03-10
TR200101032T2 (en) 2001-10-22
WO2000020612A3 (en) 2000-07-06
KR20010085901A (en) 2001-09-07
EP1117817A2 (en) 2001-07-25
PL347904A1 (en) 2002-04-22
HUP0103616A2 (en) 2002-01-28
BR9915919A (en) 2001-08-21
AU6334099A (en) 2000-04-26
AU758817B2 (en) 2003-04-03
RU2003131696A (en) 2005-04-20
WO2000020612A2 (en) 2000-04-13
JP2002526116A (en) 2002-08-20
CA2344269A1 (en) 2000-04-13
HUP0103616A3 (en) 2003-07-28
CN1330718A (en) 2002-01-09

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