AR026621A1 - Sistemas terapeuticos transdermales con estabilidad mejorada y un procedimiento para su preparacion - Google Patents
Sistemas terapeuticos transdermales con estabilidad mejorada y un procedimiento para su preparacionInfo
- Publication number
- AR026621A1 AR026621A1 ARP000106240A ARP000106240A AR026621A1 AR 026621 A1 AR026621 A1 AR 026621A1 AR P000106240 A ARP000106240 A AR P000106240A AR P000106240 A ARP000106240 A AR P000106240A AR 026621 A1 AR026621 A1 AR 026621A1
- Authority
- AR
- Argentina
- Prior art keywords
- preparation
- transdermal therapeutic
- procedure
- improved stability
- tts
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 3
- 230000001225 therapeutic effect Effects 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 150000002432 hydroperoxides Chemical class 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 150000002978 peroxides Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
Abstract
La presente se refiere a un sistema terapéutico transdermal (TTS), en el cual se reduce la formacion de productos de descomposicion por oxidacion de por lomenos una substancia activa contenida en este sistema y oxidable por medio de hidroperoxidos du rante el almacenamiento de dicho TTS, que está caracterizadoporque la suma de los índices de peroxido (POZ), que poseen en cada caso las proporciones indicadas para el TTS por las indicaciones de preparacion de la o delas substancias activas, es de 2 0 como máximo. La invencion se refiere además a un procedimiento para la preparacion de dicho sistema terapéutico transdermal.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19957401 | 1999-11-29 | ||
| DE10054713A DE10054713C2 (de) | 1999-11-29 | 2000-11-04 | Transdermale Therapeutische Systeme mit verbesserter Stabilität und ein Verfahren zu ihrer Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR026621A1 true AR026621A1 (es) | 2003-02-19 |
Family
ID=26007565
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP000106240A AR026621A1 (es) | 1999-11-29 | 2000-11-27 | Sistemas terapeuticos transdermales con estabilidad mejorada y un procedimiento para su preparacion |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6699498B1 (es) |
| EP (1) | EP1233763B1 (es) |
| JP (1) | JP5753645B2 (es) |
| CN (1) | CN1195506C (es) |
| AR (1) | AR026621A1 (es) |
| AT (1) | ATE245972T1 (es) |
| AU (1) | AU779523B2 (es) |
| BR (1) | BRPI0015939B8 (es) |
| CA (1) | CA2396686C (es) |
| CZ (1) | CZ295031B6 (es) |
| DK (1) | DK1233763T3 (es) |
| ES (1) | ES2204732T3 (es) |
| HU (1) | HU228822B1 (es) |
| IL (1) | IL149812A0 (es) |
| MX (1) | MXPA02005292A (es) |
| NZ (1) | NZ519069A (es) |
| PL (1) | PL198323B1 (es) |
| PT (1) | PT1233763E (es) |
| RU (1) | RU2266735C2 (es) |
| TW (1) | TWI272108B (es) |
| WO (1) | WO2001039753A1 (es) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19814084B4 (de) * | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
| US20070243240A9 (en) * | 2000-08-24 | 2007-10-18 | Fred Windt-Hanke | Transdermal therapeutic system |
| DE10053397A1 (de) * | 2000-10-20 | 2002-05-02 | Schering Ag | Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen |
| DE10066158B4 (de) * | 2000-08-24 | 2007-08-09 | Neurobiotec Gmbh | Verwendung eines transdermalen therapeutischen Systems zur Behandlung des Restless-Legs-Syndroms |
| DE10064453A1 (de) * | 2000-12-16 | 2002-07-04 | Schering Ag | Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen |
| US20030026830A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine |
| US20030027793A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal treatment of parkinson's disease |
| US20060263419A1 (en) * | 2002-03-12 | 2006-11-23 | Hans-Michael Wolff | Transdermal therapeutic system for Parkinson's Disease |
| US20060216336A1 (en) * | 2002-05-07 | 2006-09-28 | Hans-Michael Wolff | Transdermal therapeutic system for Parkinson's Disease |
| DE10224612A1 (de) * | 2002-06-04 | 2003-12-24 | Lohmann Therapie Syst Lts | Wirkstoffhaltige filmförmige Zubereitungen mit verbesserter chemischer Stabilität, und Verfahren zu deren Herstellung |
| US8246979B2 (en) | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system for the administration of rotigotine |
| DE10234673B4 (de) * | 2002-07-30 | 2007-08-16 | Schwarz Pharma Ag | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
| US8211462B2 (en) * | 2002-07-30 | 2012-07-03 | Ucb Pharma Gmbh | Hot-melt TTS for administering rotigotine |
| EP1426049B1 (en) * | 2002-12-02 | 2005-05-18 | Schwarz Pharma Ag | Iontophoretic delivery of rotigotine for the treatment of Parkinson's disease |
| DE10261696A1 (de) * | 2002-12-30 | 2004-07-15 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base |
| TW200514582A (en) * | 2003-10-31 | 2005-05-01 | Hisamitsu Pharmaceutical Co | Transdermal preparation and method for reducing side effect in pergolide therapy |
| US7537774B2 (en) * | 2005-12-23 | 2009-05-26 | Orion Therapeautics, Llc | Therapeutic formulation |
| US8563031B2 (en) * | 2010-05-27 | 2013-10-22 | Absize, Inc. | Piroxicam-containing matrix patches and methods for the topical treatment of acute and chronic pain and inflammation therewith |
| DE102017104026A1 (de) | 2017-02-27 | 2018-08-30 | Lts Lohmann Therapie-Systeme Ag | Nicotin enthaltendes transparentes transdermales therapeutisches System |
| WO2020250840A1 (ja) * | 2019-06-14 | 2020-12-17 | 久光製薬株式会社 | ロチゴチン含有貼付剤 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56103117A (en) * | 1980-01-19 | 1981-08-18 | Nitto Electric Ind Co Ltd | Stabilized plaster containing drug |
| JPS60199832A (ja) * | 1984-03-22 | 1985-10-09 | Nitto Electric Ind Co Ltd | 抗酸化性外用製剤 |
| FR2619388A1 (fr) | 1987-08-14 | 1989-02-17 | Rhone Poulenc Chimie | Article stratifie souple pour adhesif de transfert |
| JPH01249885A (ja) * | 1988-03-30 | 1989-10-05 | Narisu Keshohin:Kk | 脂質の酸化防止剤 |
| DE3910578A1 (de) * | 1989-03-29 | 1990-10-04 | Schering Ag | Mittel zur transdermalen applikation enthaltend gestoden |
| JP2788754B2 (ja) * | 1989-05-12 | 1998-08-20 | 日東電工株式会社 | シート状経皮吸収デバイス |
| JPH03232817A (ja) * | 1990-02-07 | 1991-10-16 | Showa Yakuhin Kako Kk | 貼付剤 |
| IE82916B1 (en) * | 1990-11-02 | 2003-06-11 | Elan Corp Plc | Formulations and their use in the treatment of neurological diseases |
| JP2869167B2 (ja) * | 1990-08-09 | 1999-03-10 | 日東電工株式会社 | 徐放性貼付製剤 |
| JP3723229B2 (ja) * | 1991-03-12 | 2005-12-07 | 武田薬品工業株式会社 | 外用貼付剤 |
| JP3034077B2 (ja) * | 1991-04-19 | 2000-04-17 | 久光製薬株式会社 | メラニン抑制貼付剤 |
| DE4210711A1 (de) * | 1991-10-31 | 1993-05-06 | Schering Ag Berlin Und Bergkamen, 1000 Berlin, De | Transdermale therapeutische systeme mit kristallisationsinhibitoren |
| JPH05306227A (ja) * | 1992-04-27 | 1993-11-19 | Lion Corp | 徐放性口腔内疾患治療剤 |
| JPH0624969A (ja) * | 1992-07-09 | 1994-02-01 | Teikoku Seiyaku Co Ltd | ケトプロフェン含有外用貼付剤 |
| DE4224325C1 (de) * | 1992-07-23 | 1994-02-10 | Sanol Arznei Schwarz Gmbh | Wirkstoffpflaster für niedrigschmelzende und/oder flüchtige Wirkstoffe und Verfahren zu seiner Herstellung |
| DE4336557C2 (de) * | 1993-05-06 | 1997-07-17 | Lohmann Therapie Syst Lts | Estradiolhaltiges transdermales therapeutisches System, Verfahren zu seiner Herstellung und seine Verwendung |
| IL109539A0 (en) | 1994-05-03 | 1994-08-26 | Yissum Res Dev Co | Substained-release pharmaceutical system for the delivery of antioxidants |
| JP3157082B2 (ja) * | 1994-09-22 | 2001-04-16 | 昭和薬品化工株式会社 | 医療用パック型製剤用基剤および医療用パック型製剤 |
| JP3117619B2 (ja) * | 1995-06-07 | 2000-12-18 | 花王株式会社 | (メタ)アクリル酸系(共)重合体の製造方法 |
| JP3361674B2 (ja) * | 1995-11-08 | 2003-01-07 | 日本カーバイド工業株式会社 | 医療用粘着剤組成物 |
| FR2744368B1 (fr) * | 1996-02-02 | 1998-04-24 | Fabre Pierre Dermo Cosmetique | Composition dermocosmetique contenant du retinal |
| DE19700913C2 (de) * | 1997-01-14 | 2001-01-04 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System zur Abgabe von Hormonen |
| US6017950A (en) * | 1997-08-05 | 2000-01-25 | Millennium Pharmaceuticals, Inc. | Methods for controlling gram negative bacteria in mammals |
| GB9720470D0 (en) * | 1997-09-25 | 1997-11-26 | Ethical Pharmaceuticals South | Inhibition of crystallization in transdermal devices |
| GB9800526D0 (en) * | 1998-01-12 | 1998-03-11 | Ciba Geigy Ag | Organic compounds |
| DE19814084B4 (de) * | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
| JP4275768B2 (ja) * | 1998-06-18 | 2009-06-10 | 久光製薬株式会社 | 水性粘着膏体 |
-
2000
- 2000-11-24 AU AU21623/01A patent/AU779523B2/en not_active Expired
- 2000-11-24 CZ CZ20021867A patent/CZ295031B6/cs not_active IP Right Cessation
- 2000-11-24 WO PCT/EP2000/011692 patent/WO2001039753A1/de not_active Ceased
- 2000-11-24 MX MXPA02005292A patent/MXPA02005292A/es active IP Right Grant
- 2000-11-24 EP EP00985090A patent/EP1233763B1/de not_active Expired - Lifetime
- 2000-11-24 NZ NZ519069A patent/NZ519069A/en not_active IP Right Cessation
- 2000-11-24 RU RU2002118325/15A patent/RU2266735C2/ru active Protection Beyond IP Right Term
- 2000-11-24 CA CA002396686A patent/CA2396686C/en not_active Expired - Lifetime
- 2000-11-24 AT AT00985090T patent/ATE245972T1/de active
- 2000-11-24 PT PT00985090T patent/PT1233763E/pt unknown
- 2000-11-24 BR BRPI0015939A patent/BRPI0015939B8/pt not_active IP Right Cessation
- 2000-11-24 JP JP2001541486A patent/JP5753645B2/ja not_active Expired - Lifetime
- 2000-11-24 CN CNB008163502A patent/CN1195506C/zh not_active Expired - Lifetime
- 2000-11-24 IL IL14981200A patent/IL149812A0/xx active IP Right Grant
- 2000-11-24 DK DK00985090T patent/DK1233763T3/da active
- 2000-11-24 PL PL355606A patent/PL198323B1/pl unknown
- 2000-11-24 ES ES00985090T patent/ES2204732T3/es not_active Expired - Lifetime
- 2000-11-24 HU HU0203318A patent/HU228822B1/hu unknown
- 2000-11-27 US US09/723,130 patent/US6699498B1/en not_active Expired - Lifetime
- 2000-11-27 TW TW089125152A patent/TWI272108B/zh not_active IP Right Cessation
- 2000-11-27 AR ARP000106240A patent/AR026621A1/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| PL355606A1 (en) | 2004-05-04 |
| CZ20021867A3 (cs) | 2002-11-13 |
| MXPA02005292A (es) | 2002-12-11 |
| US6699498B1 (en) | 2004-03-02 |
| CA2396686C (en) | 2008-07-08 |
| NZ519069A (en) | 2004-06-25 |
| PL198323B1 (pl) | 2008-06-30 |
| AU779523B2 (en) | 2005-01-27 |
| BR0015939B1 (pt) | 2013-10-08 |
| PT1233763E (pt) | 2003-11-28 |
| CN1402633A (zh) | 2003-03-12 |
| CA2396686A1 (en) | 2001-06-07 |
| AU2162301A (en) | 2001-06-12 |
| IL149812A0 (en) | 2002-11-10 |
| JP2003515554A (ja) | 2003-05-07 |
| EP1233763B1 (de) | 2003-07-30 |
| WO2001039753A1 (de) | 2001-06-07 |
| CZ295031B6 (cs) | 2005-05-18 |
| JP5753645B2 (ja) | 2015-07-22 |
| HUP0203318A3 (en) | 2004-06-28 |
| RU2266735C2 (ru) | 2005-12-27 |
| ES2204732T3 (es) | 2004-05-01 |
| ATE245972T1 (de) | 2003-08-15 |
| RU2002118325A (ru) | 2004-02-20 |
| HUP0203318A2 (hu) | 2003-02-28 |
| EP1233763A1 (de) | 2002-08-28 |
| DK1233763T3 (da) | 2003-10-20 |
| BRPI0015939B8 (pt) | 2021-05-25 |
| BR0015939A (pt) | 2002-08-20 |
| CN1195506C (zh) | 2005-04-06 |
| TWI272108B (en) | 2007-02-01 |
| HU228822B1 (en) | 2013-05-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |