AR013945A1 - Derivado de carboestirilo; composicion farmaceutica y cosmetica; uso de dichos derivados para inhibir eritema de la piel y/o pigmentacion de la piel; y procesos para su obtencion. - Google Patents
Derivado de carboestirilo; composicion farmaceutica y cosmetica; uso de dichos derivados para inhibir eritema de la piel y/o pigmentacion de la piel; y procesos para su obtencion.Info
- Publication number
- AR013945A1 AR013945A1 ARP980104065A ARP980104065A AR013945A1 AR 013945 A1 AR013945 A1 AR 013945A1 AR P980104065 A ARP980104065 A AR P980104065A AR P980104065 A ARP980104065 A AR P980104065A AR 013945 A1 AR013945 A1 AR 013945A1
- Authority
- AR
- Argentina
- Prior art keywords
- group
- lower alkyl
- atom
- derivative
- pigmentation
- Prior art date
Links
- 206010015150 Erythema Diseases 0.000 title abstract 3
- 208000012641 Pigmentation disease Diseases 0.000 title abstract 3
- 239000002537 cosmetic Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000004429 atom Chemical group 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- CREMABGTGYGIQB-UHFFFAOYSA-N carbon carbon Chemical compound C.C CREMABGTGYGIQB-UHFFFAOYSA-N 0.000 abstract 1
- 239000011203 carbon fibre reinforced carbon Substances 0.000 abstract 1
- 150000001875 compounds Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000002500 effect on skin Effects 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 230000019612 pigmentation Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
- 125000001412 tetrahydropyranyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Abstract
Un agente para inhibir eritema de la piel y/o pigmentacion de la piel, conteniendo por lo menos un compuesto seleccionado del grupo que consite en underivado de carboestirilo y la sal del mismo representada por la formula general (I) (endonde R1 es un átomo de hidrogeno, un grupo alquilo inferior oun grupo alquenilo inferior; R2 es un átomo de hidrogeno, un grupo alquilo inferior, un grupro alcoxilo inferior, un grupo alqueniloxilo inferior; ungrupo alquenilo inferior o ungrup o tetrahidropiranilo; R3 y R4 son iguales o diferentes el uno del otro y son grupos alquilo inferior que pueden poseergrupos hidroxilos como sustituyentes; adicionalmente R3 y R4 pueden formar, junto con el átomo de nitrogeno adyacente,además con o sin un átomo denitrogeno, átomo de oxígeno o átomo de azufre adicional, un grupo heterocíclico saturado de 5- o 6-, miembros que puede poseer sustituyentes selecionados delgrupo que consiste de un grupo alquilo inferior y un grupoalcanoilo inf erior; el enlace carbono - carbono entre posiciones 1- y 4- en el esqueletocarbostirilo es un enlace simple o enlace doble; a condicion que cuando R3 y R4 sean grupos alquilo inferior a la vez, entonces R2 no debe ser ni unátomode hidrogeno, ni un grupo alquilo inferior ni un grupo alcoxilo inferior). Uso de dicho derivado para preparar agentes para prevenir y tratar dermopatías odermatitis o inhibir eritema de la piel y/o pigmentacion de la misma y un procesopara la preparacion de los derivados descriptos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP22243197 | 1997-08-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR013945A1 true AR013945A1 (es) | 2001-01-31 |
Family
ID=16782296
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980104065A AR013945A1 (es) | 1997-08-19 | 1998-08-18 | Derivado de carboestirilo; composicion farmaceutica y cosmetica; uso de dichos derivados para inhibir eritema de la piel y/o pigmentacion de la piel; y procesos para su obtencion. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6133264A (es) |
| EP (1) | EP1005458B1 (es) |
| JP (1) | JPH11124366A (es) |
| KR (1) | KR100397201B1 (es) |
| CN (1) | CN1141298C (es) |
| AR (1) | AR013945A1 (es) |
| AT (1) | ATE279395T1 (es) |
| AU (1) | AU725464B2 (es) |
| BR (1) | BR9811307A (es) |
| CA (1) | CA2297439C (es) |
| DE (1) | DE69827014T2 (es) |
| DK (1) | DK1005458T3 (es) |
| EG (1) | EG24161A (es) |
| ES (1) | ES2232001T3 (es) |
| ID (1) | ID23521A (es) |
| MY (1) | MY115907A (es) |
| PT (1) | PT1005458E (es) |
| TW (1) | TW436483B (es) |
| WO (1) | WO1999009011A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020034772A1 (en) | 1999-06-29 | 2002-03-21 | Orlow Seth J. | Methods and compositions that affect melanogenesis |
| US20020114769A1 (en) * | 2000-09-14 | 2002-08-22 | Rotenberg Susan A. | Novel dequalinium analogs |
| WO2011094016A1 (en) | 2010-01-28 | 2011-08-04 | New York University | Compounds, compositions and methods for preventing skin darkening |
| WO2012103487A1 (en) | 2011-01-27 | 2012-08-02 | New York University | Coumarin compounds as melanogenesis modifiers and uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1219587A (en) * | 1981-12-14 | 1987-03-24 | Norman P. Jensen | Hydroxybenzylaminobenzenes as anti-inflammatory agents |
| US5082847A (en) * | 1990-07-18 | 1992-01-21 | Syntex (U.S.A.) Inc. | Carbostyril compounds connected via an oxyalkyl group with a piperidine ring and having pharmaceutical utility |
| JP3406600B2 (ja) * | 1992-05-01 | 2003-05-12 | 興和株式会社 | キノリン誘導体又はその塩，及びこれを含有する心疾患治療剤 |
| TW448161B (en) * | 1994-07-14 | 2001-08-01 | Otsuka Pharma Co Ltd | Cyclic amide derivatives |
| US6180647B1 (en) * | 1995-07-07 | 2001-01-30 | Pfizer Inc. | Substituted benzolactam compounds as substance P antagonists |
| AU706818B2 (en) * | 1996-05-20 | 1999-06-24 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| EP0918522A4 (en) * | 1996-05-20 | 1999-08-18 | Merck & Co Inc | GONADOLIBERIN ANTAGONISTS |
-
1998
- 1998-07-23 TW TW087112066A patent/TW436483B/zh not_active IP Right Cessation
- 1998-08-13 EG EG94298A patent/EG24161A/xx active
- 1998-08-17 JP JP10230407A patent/JPH11124366A/ja active Pending
- 1998-08-18 AT AT98937851T patent/ATE279395T1/de not_active IP Right Cessation
- 1998-08-18 ES ES98937851T patent/ES2232001T3/es not_active Expired - Lifetime
- 1998-08-18 CN CNB988082772A patent/CN1141298C/zh not_active Expired - Fee Related
- 1998-08-18 ID IDW20000312A patent/ID23521A/id unknown
- 1998-08-18 CA CA002297439A patent/CA2297439C/en not_active Expired - Fee Related
- 1998-08-18 DE DE69827014T patent/DE69827014T2/de not_active Expired - Fee Related
- 1998-08-18 AU AU86500/98A patent/AU725464B2/en not_active Ceased
- 1998-08-18 MY MYPI98003752A patent/MY115907A/en unknown
- 1998-08-18 PT PT98937851T patent/PT1005458E/pt unknown
- 1998-08-18 DK DK98937851T patent/DK1005458T3/da active
- 1998-08-18 BR BR9811307-0A patent/BR9811307A/pt not_active IP Right Cessation
- 1998-08-18 KR KR10-2000-7001705A patent/KR100397201B1/ko not_active Expired - Fee Related
- 1998-08-18 AR ARP980104065A patent/AR013945A1/es active IP Right Grant
- 1998-08-18 WO PCT/JP1998/003657 patent/WO1999009011A1/en not_active Ceased
- 1998-08-18 EP EP98937851A patent/EP1005458B1/en not_active Expired - Lifetime
- 1998-08-18 US US09/485,454 patent/US6133264A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69827014T2 (de) | 2005-03-17 |
| CA2297439C (en) | 2006-12-19 |
| JPH11124366A (ja) | 1999-05-11 |
| HK1029346A1 (en) | 2001-03-30 |
| PT1005458E (pt) | 2005-01-31 |
| CN1267284A (zh) | 2000-09-20 |
| TW436483B (en) | 2001-05-28 |
| KR20010023086A (ko) | 2001-03-26 |
| ES2232001T3 (es) | 2005-05-16 |
| EP1005458A1 (en) | 2000-06-07 |
| ATE279395T1 (de) | 2004-10-15 |
| WO1999009011A1 (en) | 1999-02-25 |
| US6133264A (en) | 2000-10-17 |
| BR9811307A (pt) | 2000-08-29 |
| ID23521A (id) | 2000-04-27 |
| AU725464B2 (en) | 2000-10-12 |
| EG24161A (en) | 2008-08-20 |
| KR100397201B1 (ko) | 2003-09-13 |
| EP1005458B1 (en) | 2004-10-13 |
| DE69827014D1 (de) | 2004-11-18 |
| MY115907A (en) | 2003-09-30 |
| CN1141298C (zh) | 2004-03-10 |
| DK1005458T3 (da) | 2005-01-31 |
| CA2297439A1 (en) | 1999-02-25 |
| AU8650098A (en) | 1999-03-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |