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AR012959A1 - ADJUVANT COMPOSITIONS FOR VACCINES, VACCINE COMPOSITIONS INCLUDING SUCH ADJUVANT COMPOSITIONS, PROCEDURE FOR THE MANUFACTURE OF SUCH VACCINES, THE USE OF SUCH ADJUVANT COMPOSITIONS - MATERIALS FOR ADMINISTRATION-STABILITIES FOR STABILITIES - Google Patents

ADJUVANT COMPOSITIONS FOR VACCINES, VACCINE COMPOSITIONS INCLUDING SUCH ADJUVANT COMPOSITIONS, PROCEDURE FOR THE MANUFACTURE OF SUCH VACCINES, THE USE OF SUCH ADJUVANT COMPOSITIONS - MATERIALS FOR ADMINISTRATION-STABILITIES FOR STABILITIES

Info

Publication number
AR012959A1
AR012959A1 ARP980102741A ARP980102741A AR012959A1 AR 012959 A1 AR012959 A1 AR 012959A1 AR P980102741 A ARP980102741 A AR P980102741A AR P980102741 A ARP980102741 A AR P980102741A AR 012959 A1 AR012959 A1 AR 012959A1
Authority
AR
Argentina
Prior art keywords
vaccines
compositions
adjuvant compositions
stabilities
adjuvant
Prior art date
Application number
ARP980102741A
Other languages
Spanish (es)
Original Assignee
Smithkline Beecham Biolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Biolog filed Critical Smithkline Beecham Biolog
Publication of AR012959A1 publication Critical patent/AR012959A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • AIDS & HIV (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

Emulsiones mejoradas de aceite en agua cuyas gotas tienen un diámetro sustancialmente de 300-600nm, que comprenden triglicéridos y donde el aceite esde preferencia un aceite metabolizable. Dichas emulsiones son utiles en la formulacion decomposiciones adyuvantes para vacunas. La invencion comprendelas composiciones adyuvantes formuladas con dichas emulsiones aceite-en-agua, composiciones de vacunas que incluyen dichos componentes adyuvantes, el usode las composiciones adyuvantes con la preparacion de medicamentos y procedimientos para fabricar dichas vacunas que incluyan dichos adyuvantesy un método para estabilizar emulsiones de aceite-en-agua, incorporando triglicéridos en la fase oleosa de dichas emulsiones, incluyendo de preferenciaaceites metabolizantes y triglicéridos.Improved oil-in-water emulsions whose droplets are substantially 300-600nm in diameter, which comprise triglycerides and where the oil is preferably a metabolizable oil. Such emulsions are useful in formulating adjuvant compositions for vaccines. The invention comprises adjuvant compositions formulated with said oil-in-water emulsions, vaccine compositions including said adjuvant components, the use of the adjuvant compositions with the preparation of medicaments and methods for manufacturing said vaccines including said adjuvants, and a method of stabilizing emulsions of oil-in-water, incorporating triglycerides in the oil phase of said emulsions, preferably including metabolizing oils and triglycerides.

ARP980102741A 1997-06-11 1998-06-10 ADJUVANT COMPOSITIONS FOR VACCINES, VACCINE COMPOSITIONS INCLUDING SUCH ADJUVANT COMPOSITIONS, PROCEDURE FOR THE MANUFACTURE OF SUCH VACCINES, THE USE OF SUCH ADJUVANT COMPOSITIONS - MATERIALS FOR ADMINISTRATION-STABILITIES FOR STABILITIES AR012959A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9711990.3A GB9711990D0 (en) 1997-06-11 1997-06-11 Vaccine

Publications (1)

Publication Number Publication Date
AR012959A1 true AR012959A1 (en) 2000-11-22

Family

ID=10813866

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP980102741A AR012959A1 (en) 1997-06-11 1998-06-10 ADJUVANT COMPOSITIONS FOR VACCINES, VACCINE COMPOSITIONS INCLUDING SUCH ADJUVANT COMPOSITIONS, PROCEDURE FOR THE MANUFACTURE OF SUCH VACCINES, THE USE OF SUCH ADJUVANT COMPOSITIONS - MATERIALS FOR ADMINISTRATION-STABILITIES FOR STABILITIES

Country Status (17)

Country Link
EP (1) EP0999852A1 (en)
JP (1) JP2002504106A (en)
KR (1) KR20010013644A (en)
CN (1) CN1260723A (en)
AR (1) AR012959A1 (en)
AU (1) AU728759B2 (en)
BR (1) BR9810614A (en)
CA (1) CA2293444A1 (en)
CO (1) CO4940401A1 (en)
GB (1) GB9711990D0 (en)
HU (1) HUP0004001A3 (en)
IL (1) IL133126A0 (en)
NO (1) NO996133L (en)
PL (1) PL337488A1 (en)
TR (1) TR199903048T2 (en)
WO (1) WO1998056414A1 (en)
ZA (1) ZA984969B (en)

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