AR012746A1 - Utilizacion de 1-ar(alqu)il-imidazolin-2-ona para la fabricacion de estados de ansiedad y tension y medicamentos de efectos ansioliticos utilizables endicho tratamiento. - Google Patents
Utilizacion de 1-ar(alqu)il-imidazolin-2-ona para la fabricacion de estados de ansiedad y tension y medicamentos de efectos ansioliticos utilizables endicho tratamiento.Info
- Publication number
- AR012746A1 AR012746A1 ARP980102409A ARP980102409A AR012746A1 AR 012746 A1 AR012746 A1 AR 012746A1 AR P980102409 A ARP980102409 A AR P980102409A AR P980102409 A ARP980102409 A AR P980102409A AR 012746 A1 AR012746 A1 AR 012746A1
- Authority
- AR
- Argentina
- Prior art keywords
- imidazolin
- anxiety
- ansiolytic
- alqu
- ona
- Prior art date
Links
- 208000019901 Anxiety disease Diseases 0.000 title abstract 3
- 230000036506 anxiety Effects 0.000 title abstract 3
- 230000000949 anxiolytic effect Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000004404 heteroalkyl group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 238000002483 medication Methods 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
La invencion se refiere a la utilizacion de 1-ar(alq)il-imidazolin-2-onas de formula I o sus sales farmacéuticamente utilizables para la preparacion deun medicamento para el tratamiento de estados de ansiedad y tension. También se proponen medicamentos formulados con dichos compuestos para el tratamiento deestados de ansiedad y tension. La formula I donde X = significa hidrogeno, C1-4-alcoxi, trifluormetilo, halogeno R1 o, en su caso, R2 = C1-4-alquilo,cicloalaquilo, heteroalquilo, o R1y R2 juntos significan un grupo alquileno con 2-6 átomos de carbono en el cual un grupo -CH2- puede estar reemplazado poroxígeno, nitrogen o azufre, y la cantidad de grupos -CH2- puede ascender a 0(1-aril-imidazolin-2-onas) o a I(1-aralquil-imidazolin-2-onas).
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19721580A DE19721580A1 (de) | 1997-05-23 | 1997-05-23 | Verwendung von 1-Ar(alk)yl-imidazolin-2-one zur Behandlung von Angst- und Spannungszuständen |
| PCT/DE1998/001343 WO1998052548A2 (de) | 1997-05-23 | 1998-05-14 | Verwendung von 1-ar(alk)yl-imidazolin-2-one zur behandlung von angst- und spannungszuständen |
| US09/079,802 US5994347A (en) | 1997-05-23 | 1998-05-15 | For a process for treatment of anxiety and tension |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR012746A1 true AR012746A1 (es) | 2000-11-08 |
Family
ID=26036759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980102409A AR012746A1 (es) | 1997-05-23 | 1998-05-22 | Utilizacion de 1-ar(alqu)il-imidazolin-2-ona para la fabricacion de estados de ansiedad y tension y medicamentos de efectos ansioliticos utilizables endicho tratamiento. |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US5994347A (es) |
| EP (1) | EP0979083B1 (es) |
| JP (1) | JP4838403B2 (es) |
| CN (1) | CN1150901C (es) |
| AR (1) | AR012746A1 (es) |
| AT (1) | ATE246926T1 (es) |
| AU (1) | AU745536B2 (es) |
| BG (1) | BG63378B1 (es) |
| BR (1) | BR9809666A (es) |
| CA (1) | CA2291075C (es) |
| DE (2) | DE19721580A1 (es) |
| DK (1) | DK0979083T3 (es) |
| ES (1) | ES2205516T3 (es) |
| HU (1) | HUP0003108A3 (es) |
| IL (1) | IL132652A0 (es) |
| NO (1) | NO325346B1 (es) |
| NZ (1) | NZ500849A (es) |
| PL (1) | PL193589B1 (es) |
| PT (1) | PT979083E (es) |
| RU (1) | RU2203055C2 (es) |
| SK (1) | SK284258B6 (es) |
| TR (1) | TR199902815T2 (es) |
| TW (1) | TW579294B (es) |
| WO (1) | WO1998052548A2 (es) |
| ZA (1) | ZA984197B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL166593A0 (en) | 2002-08-02 | 2006-01-15 | Racemization and enantiomer separation of clopidogrel | |
| US20050070537A1 (en) * | 2002-10-10 | 2005-03-31 | Chris Rundfeldt | Use of dihydroimidazolones for the treatment of dogs |
| JP2009513539A (ja) * | 2003-07-11 | 2009-04-02 | ベーリンガー・インゲルハイム・フエトメデイカ・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング | ベンゾジアゼピンレセプターのアルファ３サブユニットに対する選択性を有する化合物を用いて中枢神経系障害を治療または予防する方法 |
| WO2006020754A1 (en) | 2004-08-11 | 2006-02-23 | Cadbury Adams Usa Llc | Sensate compositions and delivery systems therefor |
| US9820988B2 (en) | 2014-03-24 | 2017-11-21 | Boehringer Ingelheim Vetmedica Gmbh | Treatment of epileptic disorders in feline animals |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4044021A (en) * | 1971-10-21 | 1977-08-23 | American Cyanamid Company | Tetrasubstituted imidazolidine diuretics useful in the treatment of hyperaldosteronism |
| RU94027048A (ru) * | 1994-07-18 | 1996-05-20 | Иркутский институт органической химии СО РАН | Анксиолитическое средство |
| DE19532668A1 (de) * | 1995-09-05 | 1997-03-06 | Dresden Arzneimittel | Neue, antikonvulsiv wirkende 1-Ar(alk)yl-imidazolin-2-one, die in 4-Stellung einen disubstituierten Amin-Rest enthalten, und Verfahren zu deren Herstellung |
| US5869481A (en) * | 1995-09-05 | 1999-02-09 | Arzneitmittelwerk Dresden G.M.B.H. | Anticonvulsive 1-ar(alk)ylimidazolin-2-ones and process for making |
-
1997
- 1997-05-23 DE DE19721580A patent/DE19721580A1/de not_active Withdrawn
-
1998
- 1998-05-14 ES ES98933532T patent/ES2205516T3/es not_active Expired - Lifetime
- 1998-05-14 CN CNB988053748A patent/CN1150901C/zh not_active Expired - Lifetime
- 1998-05-14 JP JP54979698A patent/JP4838403B2/ja not_active Expired - Lifetime
- 1998-05-14 BR BR9809666-4A patent/BR9809666A/pt not_active Application Discontinuation
- 1998-05-14 TR TR1999/02815T patent/TR199902815T2/xx unknown
- 1998-05-14 EP EP98933532A patent/EP0979083B1/de not_active Expired - Lifetime
- 1998-05-14 IL IL13265298A patent/IL132652A0/xx not_active IP Right Cessation
- 1998-05-14 SK SK1584-99A patent/SK284258B6/sk not_active IP Right Cessation
- 1998-05-14 DK DK98933532T patent/DK0979083T3/da active
- 1998-05-14 AT AT98933532T patent/ATE246926T1/de not_active IP Right Cessation
- 1998-05-14 DE DE59809285T patent/DE59809285D1/de not_active Expired - Lifetime
- 1998-05-14 WO PCT/DE1998/001343 patent/WO1998052548A2/de not_active Ceased
- 1998-05-14 PL PL98337090A patent/PL193589B1/pl not_active IP Right Cessation
- 1998-05-14 HU HU0003108A patent/HUP0003108A3/hu unknown
- 1998-05-14 AU AU83326/98A patent/AU745536B2/en not_active Expired
- 1998-05-14 NZ NZ500849A patent/NZ500849A/en unknown
- 1998-05-14 RU RU99128109/14A patent/RU2203055C2/ru active
- 1998-05-14 CA CA002291075A patent/CA2291075C/en not_active Expired - Lifetime
- 1998-05-14 PT PT98933532T patent/PT979083E/pt unknown
- 1998-05-15 US US09/079,802 patent/US5994347A/en not_active Expired - Lifetime
- 1998-05-19 ZA ZA9804197A patent/ZA984197B/xx unknown
- 1998-05-20 TW TW087107848A patent/TW579294B/zh not_active IP Right Cessation
- 1998-05-22 AR ARP980102409A patent/AR012746A1/es not_active Application Discontinuation
-
1999
- 1999-10-29 NO NO19995300A patent/NO325346B1/no not_active IP Right Cessation
- 1999-11-04 BG BG103859A patent/BG63378B1/bg unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |