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AR011709A1 - Un sistema de aplicacion de drogas, de preferencia con forma de anillo, adecuado para la administracion vaginal - Google Patents

Un sistema de aplicacion de drogas, de preferencia con forma de anillo, adecuado para la administracion vaginal

Info

Publication number
AR011709A1
AR011709A1 ARP980101575A ARP980101575A AR011709A1 AR 011709 A1 AR011709 A1 AR 011709A1 AR P980101575 A ARP980101575 A AR P980101575A AR P980101575 A ARP980101575 A AR P980101575A AR 011709 A1 AR011709 A1 AR 011709A1
Authority
AR
Argentina
Prior art keywords
vaginal administration
ring
preference
application system
drug application
Prior art date
Application number
ARP980101575A
Other languages
English (en)
Original Assignee
Organon Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8228203&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR011709(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Organon Nv filed Critical Organon Nv
Publication of AR011709A1 publication Critical patent/AR011709A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invencion se relaciona con un sistema de aplicacion de drogas, de preferencia con forma de anillo, adecuado para la administracionvaginal, para la liberacion simultánea de un compuesto esteroide progestogénico en una relacionfis iologica fija en un lapso prolongado. El sistema deaplicacion de drogas comprende al menos un comportamiento de comprende un nucleo polimérico termoplástico que contiene la mezcla de los compuestosprogestogénico y estrogénico y una pielpolméri ca termoplástica, estando el compuesto porgestogénico disuelto inicialmente en el material poliméricocentral en un grado relativamente bajo de supersaturacion.
ARP980101575A 1997-04-11 1998-04-07 Un sistema de aplicacion de drogas, de preferencia con forma de anillo, adecuado para la administracion vaginal AR011709A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97201098 1997-04-11

Publications (1)

Publication Number Publication Date
AR011709A1 true AR011709A1 (es) 2000-08-30

Family

ID=8228203

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP980101575A AR011709A1 (es) 1997-04-11 1998-04-07 Un sistema de aplicacion de drogas, de preferencia con forma de anillo, adecuado para la administracion vaginal

Country Status (26)

Country Link
US (1) US5989581A (es)
EP (1) EP0876815B1 (es)
JP (2) JP4982670B2 (es)
KR (1) KR100492676B1 (es)
CN (1) CN1163222C (es)
AR (1) AR011709A1 (es)
AT (1) ATE211646T1 (es)
AU (1) AU726934B2 (es)
BR (1) BR9801027B1 (es)
CA (1) CA2233753C (es)
CZ (1) CZ294099B6 (es)
DE (1) DE69803112T2 (es)
DK (1) DK0876815T3 (es)
ES (1) ES2171283T3 (es)
HU (1) HU222343B1 (es)
ID (1) ID21259A (es)
IL (2) IL123813A0 (es)
NO (1) NO320394B1 (es)
NZ (1) NZ330145A (es)
PL (1) PL192449B1 (es)
PT (1) PT876815E (es)
RU (1) RU2206325C2 (es)
SG (1) SG65061A1 (es)
TR (1) TR199800648A1 (es)
TW (1) TW358031B (es)
ZA (1) ZA982911B (es)

Families Citing this family (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW358031B (en) * 1997-04-11 1999-05-11 Akze Nobel N V Drug delivery system for 2 or more active substances
US6039968A (en) † 1997-06-24 2000-03-21 Hoechst Marion Roussel Intravaginal drug delivery device
US6361780B1 (en) * 1998-11-12 2002-03-26 Cardiac Pacemakers, Inc. Microporous drug delivery system
US6217895B1 (en) 1999-03-22 2001-04-17 Control Delivery Systems Method for treating and/or preventing retinal diseases with sustained release corticosteroids
US6371970B1 (en) 1999-07-30 2002-04-16 Incept Llc Vascular filter having articulation region and methods of use in the ascending aorta
US7369463B1 (en) 2000-02-21 2008-05-06 N.V. Organon Electronic alarm timer for use with a medical regimen
US20040115268A1 (en) * 2000-04-26 2004-06-17 Control Delivery Systems, Inc. Systemic delivery of antiviral agents
US6375972B1 (en) 2000-04-26 2002-04-23 Control Delivery Systems, Inc. Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
US7187980B2 (en) * 2001-11-09 2007-03-06 Oscor Inc. Cardiac lead with steroid eluting ring
TWI297685B (en) 2002-04-04 2008-06-11 Organon Nv Non-steroidal progesterone receptor modulators
US8871241B2 (en) * 2002-05-07 2014-10-28 Psivida Us, Inc. Injectable sustained release delivery devices
CN1658836A (zh) * 2002-05-07 2005-08-24 控制传输系统公司 形成药物传递装置的方法
DE60332769D1 (de) 2002-11-07 2010-07-08 Organon Nv Indole, die sich zur behandlung von mit dem androgenrezeptor in zusammenhang stehenden krankheiten eignen
AU2003298350A1 (en) * 2002-12-16 2004-07-09 Akzo Nobel N.V. Vessel, method and apparatus for dissolution testing of an annular pharmaceutical delivery device
US7357046B2 (en) * 2002-12-16 2008-04-15 N. V. Organon Method for dissolution testing of a pharmaceutical delivery device
JP4898431B2 (ja) 2003-04-29 2012-03-14 ザ ジェネラル ホスピタル コーポレイション 複数薬物の持続放出のための方法およびデバイス
TWI336627B (en) 2003-05-23 2011-02-01 Organon Nv Drug delivery system,and use and manufacturing method thereof
WO2005070950A1 (en) * 2004-01-15 2005-08-04 Warner Chilcott Company, Inc. Di-steroidal prodrugs of ethinyl estradiol
US7067505B2 (en) * 2004-01-15 2006-06-27 Warner Chilcott Company, Inc. Di-steroidal prodrugs of estradiol
MXPA06010905A (es) * 2004-03-24 2007-03-08 Organon Nv Sistema para el suministro de farmacos basados en copolimeros de polietileno y acetato de vinilo.
TW200531977A (en) 2004-03-25 2005-10-01 Akzo Nobel Nv Progesterone receptor modulators
TW200602317A (en) 2004-04-23 2006-01-16 Akzo Nobel Nv Novel androgens
WO2006053836A1 (en) * 2004-11-16 2006-05-26 Universite De Liege Active substance delivery system comprising a hydrogel atrix and microcarriers
CN100366242C (zh) * 2005-01-13 2008-02-06 杭州容立医药科技有限公司 防滑脱阴道药物释放体系及其制造工艺和在制药中的应用
US20100241240A1 (en) * 2005-06-20 2010-09-23 Abbeymoor Medical, Inc. Self-adjusting endourethral device & methods of use
TW200744610A (en) * 2005-06-21 2007-12-16 Organon Nv New regimens for controlled drug delivery devices for contraception
TW200727920A (en) * 2005-06-21 2007-08-01 Organon Nv New regimens for oral monophasic contraceptives
ES2523045T3 (es) * 2005-07-12 2014-11-20 Warner Chilcott Company, Llc Derivado éster de etinil estradiol
CA2610481A1 (en) * 2005-07-12 2007-01-18 Warner Chilcott Company, Inc. 3-ester prodrugs of estradiol
CN1899643B (zh) * 2005-07-20 2010-12-29 上海市计划生育科学研究所 含有抗雌激素和抗孕激素复合制剂的阴道环或宫内释药装置及其制药用途
DK1933810T3 (da) * 2005-08-11 2013-01-28 Childrens Medical Center Intravesikal lægemiddelafgivelsesindretning og fremgangsmåde
US20070077269A1 (en) * 2005-10-04 2007-04-05 Woodward John R Method of birth control and hormone regulation
US7989442B2 (en) 2006-09-27 2011-08-02 N.V. Organon Progesterone receptor modulators
MX2009005446A (es) * 2006-11-22 2009-06-02 Organon Nv Sistema de suministro vaginal para mirtazapina.
TW200840595A (en) * 2006-12-12 2008-10-16 Organon Nv Oral contraceptive spray
US8063037B2 (en) 2007-05-07 2011-11-22 N. V. Organon Progesterone receptor modulators
AR066166A1 (es) * 2007-09-21 2009-07-29 Organon Nv Sistema de suministro de droga
NZ585449A (en) 2007-12-11 2012-07-27 Massachusetts Inst Technology Implantable drug delivery device and methods for treatment of the bladder and other body vestcles or lumens
WO2010019507A2 (en) * 2008-08-09 2010-02-18 Massachusetts Institute Of Technology Implantable drug delivery device and methods of treating male genitourinary and surrounding tissues
US20100040671A1 (en) * 2008-08-12 2010-02-18 Ahmed Salah U Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof
CA2739147A1 (en) * 2008-11-07 2010-05-14 Combinent Biomedical Systems, Inc. Therapeutic peptide drug delivery and device
FI121000B (fi) * 2008-11-19 2010-06-15 Bayer Schering Pharma Oy Intravaginaalinen antojärjestelmä ja menetelmä sen valmistamiseksi
MX2011009679A (es) 2009-03-17 2011-09-30 Intervet Int Bv Dispositivo de suministro de farmaco zootecnico.
WO2010118178A2 (en) 2009-04-07 2010-10-14 Garfield Robert E Uterine electrical stimulation system and method
US8568374B2 (en) * 2009-05-04 2013-10-29 Merck Sharp & Dohme B.V. Intrauterine system
CA2764063C (en) 2009-06-03 2019-05-14 Forsight Labs, Llc Anterior segment drug delivery
BRPI1014771B1 (pt) 2009-06-26 2020-04-14 Liris Biomedical Inc dispositivo de dispensação de droga
ES2626156T3 (es) 2009-07-21 2017-07-24 The Population Council, Inc. Anillo vaginal de gradiente multicapa
US9017312B2 (en) 2009-09-10 2015-04-28 Taris Biomedical Llc Implantable device for controlled drug delivery
CN103025320A (zh) * 2010-03-28 2013-04-03 伊万斯彻有限公司 阴道内药物递送装置
EP2580191A2 (en) 2010-06-10 2013-04-17 The U.S.A. as represented by the Secretary, Department of Health and Human Services Thioether prodrug compositions as anti-hiv and anti-retroviral agents
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
CA3063888C (en) 2010-10-27 2020-12-22 Dignity Health Uterine electrical stimulation system and method
US9872983B2 (en) 2010-10-27 2018-01-23 Dignity Health Uterine electrical stimulation system and method
CA2823783C (en) 2011-01-10 2023-03-21 Taris Biomedical, Inc. Lidocaine regimen for the use of sustained treatment of bladder pain and irritative voiding
KR101263916B1 (ko) 2011-01-11 2013-05-13 이장희 성 호르몬 방출 장치 및 이를 이용한 동물 피임 및 발정 유도 방법
CN103379902B (zh) * 2011-02-04 2015-11-25 塔里斯生物医药公司 用于低溶解度药物的控制释放的可植入装置
KR20140074281A (ko) * 2011-07-20 2014-06-17 패트릭 에프. 카이저 약물 전달용 질내 장치
WO2013029194A1 (es) 2011-08-26 2013-03-07 Universidad De Santiago De Chile Uso de los anti-inflamatorios no esteroidales meloxicam y piroxicam, por via intravaginal, para la interrupción del proceso ovulatorio en la mujer
KR20150051234A (ko) 2012-09-03 2015-05-11 에쏘세아 파르밍 에쎄.아. 수생 생물종의 배향 및／또는 억제를 위한 저장조 케이지 침지 시스템
MX2015006499A (es) 2012-11-22 2015-08-14 Bayer Pharma AG Uso y regimen de aplicacion de una composicion farmaceutica que comprende levonorgestrel y un inhibidor de la cox para la anticocepcion "a la carta".
US20160022198A1 (en) 2013-03-08 2016-01-28 Li Galli B.V. Vaginal Drug Delivery and/or Diagnostic System
SG11201507294WA (en) 2013-03-15 2015-10-29 Taris Biomedical Llc Drug delivery devices with drug-permeable component and methods
HUE051336T2 (hu) 2013-08-19 2021-03-01 Taris Biomedical Llc Többadagos gyógyszeradagoló eszköz
WO2015035003A1 (en) 2013-09-05 2015-03-12 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Thioether prodrug compositions as anti-hiv and anti-retroviral agents
WO2015055789A1 (en) 2013-10-17 2015-04-23 Bayer Pharma Aktiengesellschaft INTRAVAGINAL USE OF 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, INTRAVAGINAL RINGS COMPRISING 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, AND USE THEREOF IN CONTRACEPTION
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
US10596103B2 (en) 2013-12-11 2020-03-24 Merek Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
US10918515B2 (en) 2015-03-31 2021-02-16 Merck Sharp & Dohme B.V. Vaginal ring applicator
US20160296532A1 (en) 2015-04-13 2016-10-13 Forsight Vision5, Inc. Ocular Insert Composition of a Semi-Crystalline or Crystalline Pharmaceutically Active Agent
US10894150B2 (en) 2015-04-23 2021-01-19 Taris Biomedical Llc Drug delivery devices with drug-permeable component and methods
CN108135910B (zh) 2015-05-13 2022-12-02 拜耳股份有限公司 长效药物递送装置及其在避孕中的用途
EP3272333A1 (en) 2016-07-22 2018-01-24 Chemo Research, S.L. Vaginal composition comprising a combination of estrogen and vitamin d
EP3395335A1 (en) 2017-04-24 2018-10-31 Kern Pharma, S.L. Vaginal ring for the simultaneous release of two active ingredients
DE102017113166A1 (de) * 2017-06-14 2018-12-20 Amw Gmbh Depotform zur Abgabe eines Östrogen-Wirkstoffs
US11103460B2 (en) 2017-08-07 2021-08-31 Board Of Regents, The University Of Texas System Fabrication methods for nanodelivery systems for long term controlled delivery of active pharmaceutical ingredients
WO2019226516A1 (en) 2018-05-24 2019-11-28 Celanese EVA Performance Polymers Corporation Implantable device for sustained release of a macromolecular drug compound
MX2020012459A (es) 2018-05-24 2021-04-28 Celanese Eva Performance Polymers Llc Dispositivo implantable para liberacion sostenida de un compuesto de farmaco macromolecular.
EP3803866A4 (en) 2018-05-24 2022-03-16 Nureva Inc. METHOD, APPARATUS, AND COMPUTER READABLE MATERIALS FOR MANAGING SEMI-CONSTANT (PERSISTENT) SOUND SOURCES IN MICROPHONE CATCH/HOME AREAS
CA3122847A1 (en) * 2018-12-11 2020-06-18 Lupin Inc. Drug delivery system for ultra-low dose estrogen combinations and methods and uses thereof
US20230404911A1 (en) * 2018-12-11 2023-12-21 Lupin Inc. Drug delivery system for ultra-low dose estrogen combinations and methods and uses thereof
US10632066B1 (en) 2019-02-01 2020-04-28 The Population Council, Inc. Method of providing birth control
US11529308B2 (en) 2019-06-21 2022-12-20 The Population Council, Inc. System for providing birth control
US10918649B2 (en) 2019-06-21 2021-02-16 The Population Council, Inc. System for providing birth control
US11439588B2 (en) 2019-10-12 2022-09-13 National Research Institute For Family Planning Vaginal sustained-release drug delivery system for luteal support, method for preparation and use thereof
IL293335A (en) 2019-11-27 2022-07-01 Oak Crest Inst Of Science Sustained release drug delivery device
USD935018S1 (en) 2020-04-07 2021-11-02 The Population Council, Inc. Contraceptive
EP4329734A4 (en) 2021-04-26 2025-04-02 Celanese EVA Performance Polymers LLC Implantable device for the delayed release of a macromolecular drug compound
IL314036A (en) 2022-01-06 2024-09-01 Oak Crest Inst Of Science Subdermal implant for sustained drug delivery
EP4215181A1 (en) * 2022-01-21 2023-07-26 Sever Pharma Solutions An intravaginal ring
AU2023401287A1 (en) 2022-12-02 2025-06-19 Vari Bioscience Gmbh Estriol vaginal ring
CN121038778A (zh) 2023-04-19 2025-11-28 橡冠科学研究院 阴道药物递送装置

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3040978A1 (de) * 1980-10-28 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Vaginalring
ZA857643B (en) * 1984-10-12 1986-05-28 Akzo Nv Release system for two or more active substances
US4816258A (en) * 1987-02-26 1989-03-28 Alza Corporation Transdermal contraceptive formulations
DE19975054I2 (de) * 1987-08-08 2000-04-13 Akzo Nobel Nv Kontrazeptives Implantat
JPH03123727A (ja) * 1989-10-04 1991-05-27 Nitto Denko Corp 経皮吸収製剤
HU222501B1 (hu) * 1991-06-28 2003-07-28 Endorecherche Inc. MPA-t vagy MGA-t tartalmazó nyújtott hatóanyag-felszabadulású gyógyászati készítmény és eljárás előállítására
BR9405798A (pt) * 1993-02-22 1995-12-12 Vivorx Pharmaceuticals Inc Métodos para liberação in vivo de material biológico e composições úteis dos mesmos
US5543150A (en) * 1993-09-15 1996-08-06 Columbia Laboratories, Inc. Method of progesterone delivery and affect thereof
GB9326255D0 (en) * 1993-12-23 1994-02-23 Roussel Lab Ltd Medical device for the prevention and treatment of cancer
FR2717688B1 (fr) * 1994-03-28 1996-07-05 Lhd Lab Hygiene Dietetique Système matriciel transdermique d'administration d'un oestrogène et/ou un progestatif à base d'EVA.
ES2166894T3 (es) * 1995-07-04 2002-05-01 Akzo Nobel Nv Dispositivos anulares.
US5906830A (en) * 1995-09-08 1999-05-25 Cygnus, Inc. Supersaturated transdermal drug delivery systems, and methods for manufacturing the same
TW358031B (en) * 1997-04-11 1999-05-11 Akze Nobel N V Drug delivery system for 2 or more active substances

Also Published As

Publication number Publication date
PL192449B1 (pl) 2006-10-31
HU222343B1 (hu) 2003-06-28
IL123813A0 (en) 1998-10-30
CA2233753A1 (en) 1998-10-11
BR9801027A (pt) 2000-01-11
JP4982670B2 (ja) 2012-07-25
CA2233753C (en) 2001-12-25
AU726934B2 (en) 2000-11-23
TW358031B (en) 1999-05-11
TR199800648A1 (xx) 1998-10-21
NO320394B1 (no) 2005-11-28
RU2206325C2 (ru) 2003-06-20
PT876815E (pt) 2002-07-31
HUP9800863A2 (hu) 1999-02-01
ATE211646T1 (de) 2002-01-15
AU6075198A (en) 1998-10-15
HK1016886A1 (en) 1999-11-12
ZA982911B (en) 1998-10-09
US5989581A (en) 1999-11-23
DK0876815T3 (da) 2002-04-22
HU9800863D0 (en) 1998-05-28
IL123813A (en) 2001-11-25
NO981638L (no) 1998-10-12
CN1196930A (zh) 1998-10-28
BR9801027B1 (pt) 2009-01-13
NO981638D0 (no) 1998-04-08
CN1163222C (zh) 2004-08-25
CZ110298A3 (cs) 1998-10-14
ID21259A (id) 1999-05-12
KR100492676B1 (ko) 2005-10-19
HUP9800863A3 (en) 2000-06-28
DE69803112T2 (de) 2002-07-18
SG65061A1 (en) 1999-05-25
ES2171283T3 (es) 2002-09-01
DE69803112D1 (de) 2002-02-14
JP2009256378A (ja) 2009-11-05
EP0876815A1 (en) 1998-11-11
CZ294099B6 (cs) 2004-10-13
PL325774A1 (en) 1998-10-12
EP0876815B1 (en) 2002-01-09
NZ330145A (en) 1999-05-28
JPH10287549A (ja) 1998-10-27
KR19980081290A (ko) 1998-11-25

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