AR018135A1 - Vacuna viva recombinante, utilizacion de un compuesto elegido entre los polimeros del acido acrilico o metacrilico y los copolimeros de ahidrido maleico yde derivado alquenilo y kit de vacunacion - Google Patents
Vacuna viva recombinante, utilizacion de un compuesto elegido entre los polimeros del acido acrilico o metacrilico y los copolimeros de ahidrido maleico yde derivado alquenilo y kit de vacunacionInfo
- Publication number
- AR018135A1 AR018135A1 ARP990100873A ARP990100873A AR018135A1 AR 018135 A1 AR018135 A1 AR 018135A1 AR P990100873 A ARP990100873 A AR P990100873A AR P990100873 A ARP990100873 A AR P990100873A AR 018135 A1 AR018135 A1 AR 018135A1
- Authority
- AR
- Argentina
- Prior art keywords
- acrylic
- maleic
- copyliments
- alquenile
- hydroid
- Prior art date
Links
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 title abstract 3
- 229920000642 polymer Polymers 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 150000002735 metacrylic acids Chemical class 0.000 title 1
- 238000002255 vaccination Methods 0.000 title 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- 229920001577 copolymer Polymers 0.000 abstract 2
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 abstract 2
- 150000005846 sugar alcohols Chemical class 0.000 abstract 2
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 abstract 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 abstract 1
- 229920002125 Sokalan® Polymers 0.000 abstract 1
- QYKIQEUNHZKYBP-UHFFFAOYSA-N Vinyl ether Chemical compound C=COC=C QYKIQEUNHZKYBP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- -1 allyl pentaerythrite Chemical compound 0.000 abstract 1
- 229960001631 carbomer Drugs 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 125000005395 methacrylic acid group Chemical group 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 229960000834 vinyl ether Drugs 0.000 abstract 1
- 239000013603 viral vector Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La vacuna viva recombinante comprende un vector viral que incorpora y expresa in vivo una secuencia nucleotídica heterologa, preferentemente un gen de unagente patogeno, y por lo menos un compuesto adyuvante elegido entre los polímeros acrílico o metacrílico y los copolímeros de anhídrido maleico y de derivadoalquenilo. Se trata particularmente de un polímero del ácido acrílico o metacrílico reticulado por un éter polialquenílico de azucar o de polialcohol(carbomero), en particular reticulado por una alilpentaeritrita. También se puede tratar de un copolimero de anhídrido maleico y de etileno reticulado, porejemplo por éter divinílico.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9802800A FR2775601B1 (fr) | 1998-03-03 | 1998-03-03 | Vaccins vivants recombines et adjuves |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR018135A1 true AR018135A1 (es) | 2001-10-31 |
Family
ID=9523775
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP990100873A AR018135A1 (es) | 1998-03-03 | 1999-03-02 | Vacuna viva recombinante, utilizacion de un compuesto elegido entre los polimeros del acido acrilico o metacrilico y los copolimeros de ahidrido maleico yde derivado alquenilo y kit de vacunacion |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US6713068B1 (es) |
| EP (1) | EP1058558B1 (es) |
| JP (1) | JP2002505300A (es) |
| KR (1) | KR20010041507A (es) |
| CN (2) | CN1263511C (es) |
| AR (1) | AR018135A1 (es) |
| AT (1) | ATE287728T1 (es) |
| AU (1) | AU762479B2 (es) |
| BR (1) | BR9908496A (es) |
| CA (1) | CA2321903C (es) |
| DE (1) | DE69923434T2 (es) |
| DK (1) | DK1058558T3 (es) |
| ES (1) | ES2237931T3 (es) |
| FR (1) | FR2775601B1 (es) |
| HU (1) | HU228431B1 (es) |
| IL (1) | IL137872A0 (es) |
| NZ (1) | NZ506370A (es) |
| PL (1) | PL197405B1 (es) |
| PT (1) | PT1058558E (es) |
| TW (1) | TW592700B (es) |
| WO (1) | WO1999044633A1 (es) |
| ZA (1) | ZA991662B (es) |
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| SI0968722T1 (sl) * | 1994-05-10 | 2007-10-31 | Wyeth Corp | Izboljĺ ano, modificirano ĺ˝ivo cepivo proti brsv |
| US6300118B1 (en) | 1995-06-07 | 2001-10-09 | American Home Products Corporation | Plasmids comprising a genetically altered feline immunodeficiency virus genome |
| US5849303A (en) | 1995-06-07 | 1998-12-15 | American Home Products Corporation | Recombinant feline Immunodeficiency virus subunit vaccines employing baculoviral-expressed envelope glycoproteins derived from isolate NCSU-1 and their use against feline immunodeficiency virus infection |
| US5820869A (en) * | 1995-06-07 | 1998-10-13 | American Home Products Corporation | Recombinant raccoon pox viruses and their use as an effective vaccine against feline immunodeficiency virus infection |
| ZA97452B (en) * | 1996-01-25 | 1997-08-15 | Trinity College Dublin | Streptococcus equi vaccine. |
| DE19612967A1 (de) * | 1996-04-01 | 1997-10-02 | Behringwerke Ag | Verfahren zur Vermehrung von Influenzaviren in Zellkultur, sowie die durch das Verfahren erhältlichen Influenzaviren |
| FR2750865B1 (fr) * | 1996-06-27 | 1998-12-04 | Rhone Merieux | Vaccin vivant recombinant a base d'herpesvirus canin, notamment contre la maladie de carre, la rage ou le virus parainfluenza de type 2 |
| FR2751226B1 (fr) * | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique contre les pathologies du cheval |
| US6004777A (en) * | 1997-03-12 | 1999-12-21 | Virogenetics Corporation | Vectors having enhanced expression, and methods of making and uses thereof |
| US6044777A (en) * | 1998-02-09 | 2000-04-04 | Walsh; Michael J. | Composite metal safe and method of making |
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1998
- 1998-03-03 FR FR9802800A patent/FR2775601B1/fr not_active Expired - Lifetime
-
1999
- 1999-03-01 WO PCT/FR1999/000453 patent/WO1999044633A1/fr not_active Ceased
- 1999-03-01 DE DE69923434T patent/DE69923434T2/de not_active Expired - Lifetime
- 1999-03-01 ES ES99937879T patent/ES2237931T3/es not_active Expired - Lifetime
- 1999-03-01 IL IL13787299A patent/IL137872A0/xx not_active IP Right Cessation
- 1999-03-01 BR BR9908496-1A patent/BR9908496A/pt not_active Application Discontinuation
- 1999-03-01 PT PT99937879T patent/PT1058558E/pt unknown
- 1999-03-01 EP EP99937879A patent/EP1058558B1/fr not_active Expired - Lifetime
- 1999-03-01 CN CNB998035750A patent/CN1263511C/zh not_active Expired - Lifetime
- 1999-03-01 HU HU0101207A patent/HU228431B1/hu unknown
- 1999-03-01 PL PL342820A patent/PL197405B1/pl unknown
- 1999-03-01 CA CA2321903A patent/CA2321903C/en not_active Expired - Lifetime
- 1999-03-01 AU AU32571/99A patent/AU762479B2/en not_active Expired
- 1999-03-01 US US09/622,951 patent/US6713068B1/en not_active Expired - Lifetime
- 1999-03-01 NZ NZ506370A patent/NZ506370A/en not_active IP Right Cessation
- 1999-03-01 KR KR1020007009675A patent/KR20010041507A/ko not_active Ceased
- 1999-03-01 AT AT99937879T patent/ATE287728T1/de active
- 1999-03-01 DK DK99937879T patent/DK1058558T3/da active
- 1999-03-01 CN CNA2006100086258A patent/CN1846786A/zh active Pending
- 1999-03-01 JP JP2000534234A patent/JP2002505300A/ja active Pending
- 1999-03-02 AR ARP990100873A patent/AR018135A1/es not_active Application Discontinuation
- 1999-03-02 ZA ZA9901662A patent/ZA991662B/xx unknown
- 1999-03-03 TW TW088103231A patent/TW592700B/zh not_active IP Right Cessation
-
2003
- 2003-12-12 US US10/735,429 patent/US7507416B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1058558B1 (fr) | 2005-01-26 |
| ES2237931T3 (es) | 2005-08-01 |
| PL197405B1 (pl) | 2008-03-31 |
| FR2775601A1 (fr) | 1999-09-10 |
| HUP0101207A2 (hu) | 2001-08-28 |
| AU3257199A (en) | 1999-09-20 |
| AU762479B2 (en) | 2003-06-26 |
| ATE287728T1 (de) | 2005-02-15 |
| HU228431B1 (en) | 2013-03-28 |
| TW592700B (en) | 2004-06-21 |
| US20060057163A1 (en) | 2006-03-16 |
| NZ506370A (en) | 2003-07-25 |
| BR9908496A (pt) | 2000-12-05 |
| CN1846786A (zh) | 2006-10-18 |
| PT1058558E (pt) | 2005-06-30 |
| CN1291899A (zh) | 2001-04-18 |
| PL342820A1 (en) | 2001-07-02 |
| CA2321903A1 (en) | 1999-09-10 |
| KR20010041507A (ko) | 2001-05-25 |
| FR2775601B1 (fr) | 2001-09-21 |
| EP1058558A1 (fr) | 2000-12-13 |
| DE69923434D1 (de) | 2005-03-03 |
| DE69923434T2 (de) | 2006-01-05 |
| WO1999044633A1 (fr) | 1999-09-10 |
| IL137872A0 (en) | 2001-10-31 |
| JP2002505300A (ja) | 2002-02-19 |
| DK1058558T3 (da) | 2005-06-06 |
| HUP0101207A3 (en) | 2003-10-28 |
| CA2321903C (en) | 2011-05-31 |
| CN1263511C (zh) | 2006-07-12 |
| US7507416B2 (en) | 2009-03-24 |
| US6713068B1 (en) | 2004-03-30 |
| ZA991662B (en) | 2000-10-12 |
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