AR008133A1 - DERIVADOS DEL ACIDO 6,7,8,9-TETRAHIDRO-5H-IMIDAZO(1,2-a)AZEPIN-3-ACETICO, PROCEDIMIENTO PARA SU PREPARACION Y COMPOSICIONES FARMACEUTICAS FOMULADAS CONDICHOS DERIVADOS. - Google Patents
DERIVADOS DEL ACIDO 6,7,8,9-TETRAHIDRO-5H-IMIDAZO(1,2-a)AZEPIN-3-ACETICO, PROCEDIMIENTO PARA SU PREPARACION Y COMPOSICIONES FARMACEUTICAS FOMULADAS CONDICHOS DERIVADOS.Info
- Publication number
- AR008133A1 AR008133A1 ARP970103473A ARP970103473A AR008133A1 AR 008133 A1 AR008133 A1 AR 008133A1 AR P970103473 A ARP970103473 A AR P970103473A AR P970103473 A ARP970103473 A AR P970103473A AR 008133 A1 AR008133 A1 AR 008133A1
- Authority
- AR
- Argentina
- Prior art keywords
- derivatives
- group
- acetico
- azepin
- imidazo
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- -1 methoxy, methylthio, methylsulfinyl Chemical group 0.000 abstract 2
- 230000001773 anti-convulsant effect Effects 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 229960003965 antiepileptics Drugs 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004186 cyclopropylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000004170 methylsulfonyl group Chemical group [H]C([H])([H])S(*)(=O)=O 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000006513 pyridinyl methyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Compuestos de fórmula (I): en la cual Z representa sea un grupo fenilo eventualmente sustituido por uno o dos átomos o grupos elegidos entre loshalógenos y los grupos alquilo de 1 a 4 átomos de carbono, metoxi, metiltio, metilsulfinilo y metilsulfonilo, sea un grupo 5-metiltién-2-ilo; R1 representaun átomo de hidrógeno o un grupo alquilo de 1 a 4 átomos de carbono, un grupo ciclopropilmetilo, un grupo fenilmetilo o un grupo piridinilmetilo, y R2representa un átomo de hidrógeno o un grupo alquilo de 1 a 4 átomos de carbono. También se propone un procedimiento para preparar dichos derivados y tambiénformulaciones de aplicación como anticonvulsivo.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9609702A FR2751970B1 (fr) | 1996-08-01 | 1996-08-01 | Derives d'acide 6,7,8,9-tetrahydro-5h-imidazo[1,2-a]azepine- 3-acetique, leur preparation et leur application en therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR008133A1 true AR008133A1 (es) | 1999-12-09 |
Family
ID=9494718
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP970103473A AR008133A1 (es) | 1996-08-01 | 1997-07-31 | DERIVADOS DEL ACIDO 6,7,8,9-TETRAHIDRO-5H-IMIDAZO(1,2-a)AZEPIN-3-ACETICO, PROCEDIMIENTO PARA SU PREPARACION Y COMPOSICIONES FARMACEUTICAS FOMULADAS CONDICHOS DERIVADOS. |
Country Status (6)
| Country | Link |
|---|---|
| AR (1) | AR008133A1 (es) |
| AU (1) | AU3853197A (es) |
| FR (1) | FR2751970B1 (es) |
| TW (1) | TW354296B (es) |
| WO (1) | WO1998005664A1 (es) |
| ZA (1) | ZA976828B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2783828B1 (fr) * | 1998-09-29 | 2000-11-10 | Synthelabo | Derives d'acide 5,6-dihydro-4h-imidazo[1,2-a][1] benzazepine -1-acetique, leur preparation et leur application en therapeutique |
| CA2648569C (en) * | 2006-04-12 | 2012-02-07 | Merck & Co., Inc. | Pyridyl amide t-type calcium channel antagonists |
| RU2010120671A (ru) | 2007-10-24 | 2011-11-27 | Мерк Шарп Энд Домэ Корп. (Us) | Гетероциклические фениламидные антагонисты кальциевых каналов т-типа |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2593817B1 (fr) * | 1986-01-31 | 1988-04-15 | Synthelabo | Derives de tetrahydro-5,6,7,8 imidazo(1,2-a)pyridine, leur preparation et leur application en therapeutique |
-
1996
- 1996-08-01 FR FR9609702A patent/FR2751970B1/fr not_active Expired - Fee Related
-
1997
- 1997-07-23 WO PCT/FR1997/001365 patent/WO1998005664A1/fr not_active Ceased
- 1997-07-23 AU AU38531/97A patent/AU3853197A/en not_active Abandoned
- 1997-07-30 TW TW086110878A patent/TW354296B/zh active
- 1997-07-31 ZA ZA9706828A patent/ZA976828B/xx unknown
- 1997-07-31 AR ARP970103473A patent/AR008133A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2751970B1 (fr) | 1998-08-28 |
| WO1998005664A1 (fr) | 1998-02-12 |
| FR2751970A1 (fr) | 1998-02-06 |
| AU3853197A (en) | 1998-02-25 |
| TW354296B (en) | 1999-03-11 |
| ZA976828B (en) | 1998-02-11 |
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