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AR007052A1 - Un derivado de carbohidrato, su uso y una composicion farmaceutica que lo comprende - Google Patents

Un derivado de carbohidrato, su uso y una composicion farmaceutica que lo comprende

Info

Publication number
AR007052A1
AR007052A1 ARP970101915A ARP970101915A AR007052A1 AR 007052 A1 AR007052 A1 AR 007052A1 AR P970101915 A ARP970101915 A AR P970101915A AR P970101915 A ARP970101915 A AR P970101915A AR 007052 A1 AR007052 A1 AR 007052A1
Authority
AR
Argentina
Prior art keywords
pharmaceutical composition
carbohydrate derivative
carbohydrate
ch2oso3
nhso3
Prior art date
Application number
ARP970101915A
Other languages
English (en)
Original Assignee
Dupuis Laurent
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dupuis Laurent filed Critical Dupuis Laurent
Publication of AR007052A1 publication Critical patent/AR007052A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Derivados de carbohidrato que tienen la fórmula I , donde R1 es H o CH2OSO3-; R2 y R3 son independientemente H, alquilo (C1-6) o SO3-; R4 es OSO3- o NHSO3-; n es 0 o 1; p es 1 o 2; o una sal farmacéuticamente aceptabl de los mismos. Loscompuestos de la invención tienen actividad antitrombótica y pueden serusados para inhibir la proliferación de las células de los músculos lisos.
ARP970101915A 1996-05-08 1997-05-08 Un derivado de carbohidrato, su uso y una composicion farmaceutica que lo comprende AR007052A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96201267 1996-05-08

Publications (1)

Publication Number Publication Date
AR007052A1 true AR007052A1 (es) 1999-10-13

Family

ID=8223964

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP970101915A AR007052A1 (es) 1996-05-08 1997-05-08 Un derivado de carbohidrato, su uso y una composicion farmaceutica que lo comprende

Country Status (26)

Country Link
US (1) US5872110A (es)
EP (1) EP0818459B1 (es)
JP (1) JP4201360B2 (es)
KR (1) KR100443802B1 (es)
CN (1) CN1115345C (es)
AR (1) AR007052A1 (es)
AT (1) ATE215547T1 (es)
AU (1) AU711630B2 (es)
BR (1) BRPI9703099B8 (es)
CA (1) CA2204204C (es)
CZ (1) CZ292439B6 (es)
DE (1) DE69711505T2 (es)
DK (1) DK0818459T3 (es)
ES (1) ES2176609T3 (es)
HU (1) HU226370B1 (es)
ID (1) ID17932A (es)
IL (1) IL120722A (es)
NO (1) NO308251B1 (es)
NZ (1) NZ314745A (es)
PL (1) PL183469B1 (es)
PT (1) PT818459E (es)
RU (1) RU2183638C2 (es)
SG (2) SG55310A1 (es)
TR (1) TR199700354A2 (es)
TW (1) TW498078B (es)
ZA (1) ZA973892B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2251090T3 (es) * 1997-05-27 2006-04-16 Sanofi-Aventis Dispositivo y metodo para aplicar articulos planos.
ATE405580T1 (de) * 1998-06-17 2008-09-15 Organon Nv Antithrombotische verbindungen
JP2003504428A (ja) * 1999-06-30 2003-02-04 ハミルトン シビック ホスピタルズ リサーチ ディベロップメント インコーポレイテッド クロット関連凝固因子を阻害するヘパリン組成物
DE20022960U1 (de) * 1999-11-12 2002-07-25 Emisphere Technologies, Inc., Tarrytown, N.Y. Flüssige Heparinformulierung
US8600783B2 (en) * 2000-08-18 2013-12-03 The Crawford Group, Inc. Business to business computer system for communicating and processing rental car reservations using web services
WO2002020091A2 (en) * 2000-09-08 2002-03-14 Hamilton Civic Hospitals Research Development Inc. Antithrombotic compositions
JP5139797B2 (ja) * 2004-03-04 2013-02-06 プロジェン ファーマシューティカルズ リミテッド 硫酸化オリゴ糖誘導体
UA87154C2 (uk) * 2004-08-05 2009-06-25 Івакс Драг Рісерч Інстітьют Лтд. Полісульфатовані глікозиди та їх солі
RU2430729C2 (ru) * 2009-05-13 2011-10-10 Учреждение Российской академии наук Институт химии Коми научного центра Уральского отделения РАН Получение полифункциональных сульфатированных производных на основе порошковой целлюлозы, обладающих антикоагулянтной активностью
CN109134553B (zh) * 2017-06-15 2021-09-28 南京正大天晴制药有限公司 抗凝血的五糖类化合物及其制备方法和医药用途
CN109134554B (zh) * 2017-06-15 2021-09-28 南京正大天晴制药有限公司 抗凝血的五糖类化合物及其制备方法和医药用途
CN109134555B (zh) * 2017-06-15 2021-09-28 南京正大天晴制药有限公司 抗凝血的五糖类化合物及其制备方法和医药用途
CN111057115B (zh) * 2019-12-17 2022-03-22 广东海洋大学 一种从贵妃蚌中提取的抗血栓类肝素及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0300099A1 (en) * 1987-07-20 1989-01-25 Akzo N.V. New pentasaccharides
EP0347964A1 (en) * 1988-06-21 1989-12-27 Akzo N.V. New oligosaccharides with internal spacer
US5378829A (en) * 1990-04-23 1995-01-03 Akzo N.V. Sulfated glycosaminoglycanoid derivatives of the heparin and heparan sulfate type
IE64378B1 (en) * 1990-04-23 1995-07-26 Akzo Nv Carbohydrate derivatives comprising a trisaccharide unit
US5707973A (en) * 1991-04-23 1998-01-13 Rhone-Poulenc Rorer S.A. Sulfated polysaccharids for treatment or prevention of thromboses
IL102758A (en) * 1991-08-23 1997-03-18 Akzo Nv Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them
FR2704226B1 (fr) * 1993-04-22 1995-07-21 Sanofi Elf 3-desoxy oligosaccharides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
BRPI9703099B8 (pt) 2021-07-06
MX9703365A (es) 1998-06-30
DE69711505T2 (de) 2002-09-26
IL120722A0 (en) 1997-08-14
EP0818459A3 (en) 1998-04-29
BRPI9703099A (pt) 1998-09-08
CA2204204C (en) 2006-02-28
ATE215547T1 (de) 2002-04-15
AU2008697A (en) 1997-11-13
KR100443802B1 (ko) 2004-10-08
HUP9700852A3 (en) 1998-08-28
HUP9700852A2 (en) 1997-12-29
HU9700852D0 (en) 1997-06-30
EP0818459B1 (en) 2002-04-03
NO308251B1 (no) 2000-08-21
AU711630B2 (en) 1999-10-21
IL120722A (en) 1999-07-14
TW498078B (en) 2002-08-11
NO972120L (no) 1997-11-10
DE69711505D1 (de) 2002-05-08
NZ314745A (en) 1998-09-24
JPH1045805A (ja) 1998-02-17
PT818459E (pt) 2002-08-30
HU226370B1 (en) 2008-09-29
JP4201360B2 (ja) 2008-12-24
PL319843A1 (en) 1997-11-10
SG46779A1 (en) 1998-01-20
EP0818459A2 (en) 1998-01-14
ID17932A (id) 1998-02-12
CZ292439B6 (cs) 2003-09-17
TR199700354A3 (tr) 1997-11-21
HK1004399A1 (en) 1998-11-27
NO972120D0 (no) 1997-05-07
CZ138697A3 (cs) 1998-02-18
CN1115345C (zh) 2003-07-23
DK0818459T3 (da) 2002-07-01
ES2176609T3 (es) 2002-12-01
BRPI9703099B1 (pt) 2016-07-19
SG55310A1 (en) 1998-12-21
KR19980018097A (ko) 1998-06-05
CN1169433A (zh) 1998-01-07
ZA973892B (en) 1998-08-19
RU2183638C2 (ru) 2002-06-20
US5872110A (en) 1999-02-16
TR199700354A2 (xx) 1997-11-21
PL183469B1 (pl) 2002-06-28
CA2204204A1 (en) 1997-11-08

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