AR006139A1 - Glutarimida, procedimientos para su preparación y su utilización. - Google Patents
Glutarimida, procedimientos para su preparación y su utilización.Info
- Publication number
- AR006139A1 AR006139A1 ARP970100909A ARP970100909A AR006139A1 AR 006139 A1 AR006139 A1 AR 006139A1 AR P970100909 A ARP970100909 A AR P970100909A AR P970100909 A ARP970100909 A AR P970100909A AR 006139 A1 AR006139 A1 AR 006139A1
- Authority
- AR
- Argentina
- Prior art keywords
- preparation
- glutarimide
- procedures
- substituents
- glutarimides
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 3
- KNCYXPMJDCCGSJ-UHFFFAOYSA-N piperidine-2,6-dione Chemical compound O=C1CCCC(=O)N1 KNCYXPMJDCCGSJ-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- -1 3, 3-disubstituted piperidines Chemical class 0.000 abstract 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical group C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms
- C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se refiere a glutarimidas de fórmula (I), en la cual Ar es un fenilo no sustituido o sustituido una o varias veces por uno de los sustituyenteselegidos entre un átomo de halógeno, un hidroxilo, un (C1-C4)alcoxi, un trifluorometilo, un(C1 -C4)alquilo, siendo dichos sustituyentes idénticos odiferentes; un grupo piridilo; un grupo tienilo y X es metileno o etileno, sus sales y sus enantiómeros, así como su proceso de preparación y su utilizaciónpara la preparación de laspiperidinas 3, 3-disustituidas correspondientes.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9602880A FR2745811B1 (fr) | 1996-03-07 | 1996-03-07 | Glutarimide disubstitue procede pour sa preparation, et son utilisation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR006139A1 true AR006139A1 (es) | 1999-08-11 |
Family
ID=9489959
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP970100909A AR006139A1 (es) | 1996-03-07 | 1997-03-07 | Glutarimida, procedimientos para su preparación y su utilización. |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US6008360A (es) |
| EP (1) | EP0888304B1 (es) |
| JP (1) | JP3116051B2 (es) |
| AR (1) | AR006139A1 (es) |
| AT (1) | ATE206399T1 (es) |
| AU (1) | AU2163497A (es) |
| BR (1) | BR9707943C8 (es) |
| CA (1) | CA2244771C (es) |
| CY (1) | CY2276B1 (es) |
| DE (1) | DE69707114T2 (es) |
| DK (1) | DK0888304T3 (es) |
| ES (1) | ES2165594T3 (es) |
| FR (1) | FR2745811B1 (es) |
| MY (1) | MY128754A (es) |
| NO (1) | NO314498B1 (es) |
| PT (1) | PT888304E (es) |
| TW (1) | TW381080B (es) |
| WO (1) | WO1997032852A1 (es) |
| ZA (1) | ZA971999B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2787449B3 (fr) | 1998-12-15 | 2001-01-12 | Sanofi Sa | Derives de 3-phenyl-2,6-dioxopiperidin-3-yl propionamide et leur procede de preparation |
| FR2787448B3 (fr) * | 1998-12-18 | 2001-01-12 | Sanofi Sa | Ester d'alkyle inferieur de l'acide 3-(3,4-dihalogenophenyl) -2,6-dioxopiperidine3-propionique et son mode de preparation |
| RU2152386C1 (ru) * | 1999-05-27 | 2000-07-10 | Российский Университет Дружбы Народов | Способ получения 2,3,5,6-тетраоксо-4-нитропиридата аммония |
| DE10002509A1 (de) * | 2000-01-21 | 2001-07-26 | Gruenenthal Gmbh | Substituierte Glutarimide |
| US6656953B2 (en) | 2000-12-06 | 2003-12-02 | Sepracor Inc. | 4,4-Disubstituted piperidines, and methods of use thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3379731A (en) * | 1967-06-15 | 1968-04-23 | Ciba Geigy Corp | 1, 4-dihydro-1, 4-ethano-isoquinolines |
| US3985888A (en) * | 1969-07-24 | 1976-10-12 | Richardson-Merrell Inc. | Methods of inducing sedation using certain spiroalkanone-imides |
| US3647797A (en) | 1969-07-24 | 1972-03-07 | Richardson Merrell Inc | 6-chloro - 2 3-dihydrospiro(naphthalene-(7h) 3'-piperidine)-2' 4 6'-triones |
| BE787767A (fr) * | 1971-08-21 | 1973-02-19 | Merck Patent Gmbh | Procede de preparation d'amides d'acides oxocarboxyliques et d'acides oxocarboxyliques |
| US5001125A (en) * | 1984-03-26 | 1991-03-19 | Janssen Pharmaceutica N.V. | Anti-virally active pyridazinamines |
| FR2676055B1 (fr) * | 1991-05-03 | 1993-09-03 | Sanofi Elf | Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| US5625060A (en) * | 1991-05-03 | 1997-04-29 | Elf Sanofi | Polycyclic amine compounds and their enantiomers, their method of preparation and pharmaceutical compositions on which they are present |
| FR2696178B1 (fr) * | 1992-09-30 | 1994-12-30 | Sanofi Elf | Amides basiques quaternaires, procédé pour leur préparation et compositions pharmaceutiques en contenant. |
| US5583134A (en) * | 1992-09-30 | 1996-12-10 | Sanofi | 1-azoniabicyclo[2.2.2] octanes and pharmaceutical compositions in which they are present |
| FR2719311B1 (fr) * | 1994-03-18 | 1998-06-26 | Sanofi Sa | Composés antagonistes sélectifs du récepteur NK3 humain et leur utilisation comme médicaments et outils de diagnostic. |
-
1996
- 1996-03-07 FR FR9602880A patent/FR2745811B1/fr not_active Expired - Fee Related
-
1997
- 1997-03-05 DE DE69707114T patent/DE69707114T2/de not_active Expired - Fee Related
- 1997-03-05 BR BRPI9707943-0C8A patent/BR9707943C8/pt not_active IP Right Cessation
- 1997-03-05 AU AU21634/97A patent/AU2163497A/en not_active Abandoned
- 1997-03-05 WO PCT/FR1997/000388 patent/WO1997032852A1/fr not_active Ceased
- 1997-03-05 PT PT97914357T patent/PT888304E/pt unknown
- 1997-03-05 JP JP09531525A patent/JP3116051B2/ja not_active Expired - Fee Related
- 1997-03-05 DK DK97914357T patent/DK0888304T3/da active
- 1997-03-05 EP EP97914357A patent/EP0888304B1/fr not_active Expired - Lifetime
- 1997-03-05 ES ES97914357T patent/ES2165594T3/es not_active Expired - Lifetime
- 1997-03-05 CA CA002244771A patent/CA2244771C/en not_active Expired - Fee Related
- 1997-03-05 AT AT97914357T patent/ATE206399T1/de not_active IP Right Cessation
- 1997-03-05 US US09/142,306 patent/US6008360A/en not_active Expired - Fee Related
- 1997-03-06 TW TW086102748A patent/TW381080B/zh not_active IP Right Cessation
- 1997-03-06 MY MYPI97000946A patent/MY128754A/en unknown
- 1997-03-07 AR ARP970100909A patent/AR006139A1/es active IP Right Grant
- 1997-03-07 ZA ZA9701999A patent/ZA971999B/xx unknown
-
1998
- 1998-09-04 NO NO19984083A patent/NO314498B1/no unknown
-
1999
- 1999-11-10 US US09/437,362 patent/US6242607B1/en not_active Expired - Fee Related
-
2002
- 2002-05-15 CY CY0200029A patent/CY2276B1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP3116051B2 (ja) | 2000-12-11 |
| DE69707114T2 (de) | 2002-06-06 |
| ATE206399T1 (de) | 2001-10-15 |
| NO984083D0 (no) | 1998-09-04 |
| US6242607B1 (en) | 2001-06-05 |
| FR2745811B1 (fr) | 1998-05-22 |
| ES2165594T3 (es) | 2002-03-16 |
| ZA971999B (en) | 1997-09-09 |
| MY128754A (en) | 2007-02-28 |
| WO1997032852A1 (fr) | 1997-09-12 |
| CA2244771C (en) | 2004-07-13 |
| FR2745811A1 (fr) | 1997-09-12 |
| BR9707943A (pt) | 1999-07-27 |
| BR9707943B (pt) | 2008-05-20 |
| US6008360A (en) | 1999-12-28 |
| CA2244771A1 (en) | 1997-09-12 |
| TW381080B (en) | 2000-02-01 |
| EP0888304A1 (fr) | 1999-01-07 |
| JPH11506124A (ja) | 1999-06-02 |
| NO314498B1 (no) | 2003-03-31 |
| DK0888304T3 (da) | 2002-03-04 |
| DE69707114D1 (de) | 2001-11-08 |
| CY2276B1 (en) | 2003-07-04 |
| BR9707943C8 (pt) | 2014-11-18 |
| PT888304E (pt) | 2002-02-28 |
| NO984083L (no) | 1998-09-04 |
| AU2163497A (en) | 1997-09-22 |
| EP0888304B1 (fr) | 2001-10-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |