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AP2321A - Quinoline derivatives for use as mycobactrial inhibitor. - Google Patents

Quinoline derivatives for use as mycobactrial inhibitor.

Info

Publication number
AP2321A
AP2321A AP2006003705A AP2006003705A AP2321A AP 2321 A AP2321 A AP 2321A AP 2006003705 A AP2006003705 A AP 2006003705A AP 2006003705 A AP2006003705 A AP 2006003705A AP 2321 A AP2321 A AP 2321A
Authority
AP
ARIPO
Prior art keywords
mycobactrial
inhibitor
quinoline derivatives
quinoline
derivatives
Prior art date
Application number
AP2006003705A
Other languages
English (en)
Other versions
AP2006003705A0 (en
Inventor
Jerome Emile Georges Guillemont
Elisabeth Thercse Jeanne Pasquier
David Francis Alain Lancois
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of AP2006003705A0 publication Critical patent/AP2006003705A0/xx
Application granted granted Critical
Publication of AP2321A publication Critical patent/AP2321A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
AP2006003705A 2004-01-29 2005-01-28 Quinoline derivatives for use as mycobactrial inhibitor. AP2321A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04075286 2004-01-29
PCT/EP2005/050375 WO2005075428A1 (en) 2004-01-29 2005-01-28 Quinoline derivatives for use as mycobacterial inhibitors

Publications (2)

Publication Number Publication Date
AP2006003705A0 AP2006003705A0 (en) 2006-08-31
AP2321A true AP2321A (en) 2011-11-16

Family

ID=34833674

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2006003705A AP2321A (en) 2004-01-29 2005-01-28 Quinoline derivatives for use as mycobactrial inhibitor.

Country Status (20)

Country Link
US (1) US7790894B2 (xx)
EP (1) EP1713776B1 (xx)
JP (1) JP4919810B2 (xx)
KR (1) KR101160183B1 (xx)
CN (1) CN1910154B (xx)
AP (1) AP2321A (xx)
AT (1) ATE395336T1 (xx)
AU (1) AU2005210036B2 (xx)
BR (1) BRPI0507312A (xx)
CA (1) CA2554049C (xx)
DE (1) DE602005006744D1 (xx)
EA (1) EA011572B9 (xx)
ES (1) ES2306098T3 (xx)
IL (1) IL177101A (xx)
MX (1) MXPA06008596A (xx)
NO (1) NO337253B1 (xx)
NZ (1) NZ547614A (xx)
UA (1) UA83875C2 (xx)
WO (1) WO2005075428A1 (xx)
ZA (1) ZA200606291B (xx)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO2855B1 (en) * 2005-08-03 2015-03-15 شركة جانسين فارماسوتيكا ان. في Quinoline derivatives acting as antibacterial agents
JO2684B1 (en) * 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان في Quinoline antibacterial derivatives
JO2970B1 (en) 2006-12-06 2016-03-15 جانسين فارماسوتيكا ان. في Quinoline antibacterial derivatives
JO2683B1 (en) * 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان. في Quinoline antibacterial derivatives
JO2685B1 (en) * 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان في Quinoline antibacterial derivatives
JO3271B1 (ar) 2006-12-06 2018-09-16 Janssen Pharmaceutica Nv مشتقات الكوينولين المضادة للجراثيم
WO2010083436A1 (en) 2009-01-15 2010-07-22 Rutgers, The State University Of New Jersey Benzo [c] phenanthridines as antimicrobial agents
CA2760526A1 (en) 2009-04-30 2010-11-04 Rutgers, The State University Of New Jersey Antimicrobial agents
CA2810162A1 (en) 2010-06-09 2011-12-15 Rutgers, The State University Of New Jersey Antimicrobial agents
WO2011163610A2 (en) * 2010-06-25 2011-12-29 Rutgers, The State University Of New Jersey Antimicrobial agents
RU2486175C2 (ru) * 2011-09-12 2013-06-27 Закрытое Акционерное Общество "Фарм-Синтез" Производные хинолина, в частности 5,6,7-замещенные 1-(2-хлорхинолин-3-ил)-4-диметиламино-2-(нафталин-1-ил)-1-фенилбутан-2-олы, способ получения и применение соединений
US9822108B2 (en) 2012-01-13 2017-11-21 Rutgers, The State University Of New Jersey Antimicrobial agents
CA2868002C (en) 2012-03-21 2021-07-13 Rutgers, The State University Of New Jersey Antimicrobial agents
MX358506B (es) 2012-04-27 2018-08-22 Janssen Pharmaceutica Nv Derivados de quinolina antibacterianos.
EP2841425B1 (en) 2012-04-27 2016-03-23 Janssen Pharmaceutica, N.V. Antibacterial quinoline derivatives
ES2628365T3 (es) 2012-10-16 2017-08-02 Janssen Pharmaceutica N.V. Moduladores de quinolinilo unidos a fenilo de ROR-GAMA-T
PE20150778A1 (es) 2012-10-16 2015-05-23 Janssen Pharmaceutica Nv Moduladores de quinolinilo unidos a metileno de ror-gamma-t
BR112015008515A2 (pt) 2012-10-16 2017-07-04 Janssen Pharmaceutica Nv moduladores de ror t de quinolinila ligada à heteroarila
CA2926339A1 (en) 2013-10-15 2015-04-23 Janssen Pharmaceutica Nv Alkyl linked quinolinyl modulators of roryt
US9403816B2 (en) 2013-10-15 2016-08-02 Janssen Pharmaceutica Nv Phenyl linked quinolinyl modulators of RORγt
US9284308B2 (en) 2013-10-15 2016-03-15 Janssen Pharmaceutica Nv Methylene linked quinolinyl modulators of RORγt
US9221804B2 (en) 2013-10-15 2015-12-29 Janssen Pharmaceutica Nv Secondary alcohol quinolinyl modulators of RORγt
US9328095B2 (en) 2013-10-15 2016-05-03 Janssen Pharmaceutica Nv Heteroaryl linked quinolinyl modulators of RORgammat
US10555941B2 (en) 2013-10-15 2020-02-11 Janssen Pharmaceutica Nv Alkyl linked quinolinyl modulators of RORγt
WO2015057626A1 (en) * 2013-10-15 2015-04-23 Janssen Pharmaceutica Nv QUINOLINYL MODULATORS OF RORyT
US9458150B2 (en) 2013-11-08 2016-10-04 Rutgers, The State University Of New Jersey Antimicrobial agents
US10513528B2 (en) 2016-02-25 2019-12-24 Taxis Pharmaceuticals, Inc. Synthetic processes and intermediates
WO2018183917A1 (en) 2017-03-30 2018-10-04 Taxis Pharmaceuticals, Inc. Synthetic processes and synthetic intermediates

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965572A (en) * 1996-10-28 1999-10-12 The United States Of America As Respresented By The Secretary Of The Army Methods for treating antibiotic-resistant infections
WO2004011436A1 (en) * 2002-07-25 2004-02-05 Janssen Pharmaceutica N.V. Quinoline derivatives and their use as mycobacterial inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU757059B2 (en) * 1997-06-19 2003-01-30 Sepracor, Inc. Quinoline-indole antimicrobial agents, uses and compositions related thereto
US6103905A (en) 1997-06-19 2000-08-15 Sepracor, Inc. Quinoline-indole antimicrobial agents, uses and compositions related thereto
DE69908555T2 (de) * 1998-01-26 2004-05-06 Smithkline Beecham P.L.C., Brentford Chinolinderivate als antibakterielles arzneimittel
US7338949B2 (en) * 2004-01-23 2008-03-04 Janssen Pharmaceutica N.V. Mycobacterial inhibitors

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965572A (en) * 1996-10-28 1999-10-12 The United States Of America As Respresented By The Secretary Of The Army Methods for treating antibiotic-resistant infections
WO2004011436A1 (en) * 2002-07-25 2004-02-05 Janssen Pharmaceutica N.V. Quinoline derivatives and their use as mycobacterial inhibitors

Also Published As

Publication number Publication date
BRPI0507312A (pt) 2007-06-26
EA011572B9 (ru) 2018-01-31
HK1099297A1 (en) 2007-08-10
JP4919810B2 (ja) 2012-04-18
CN1910154B (zh) 2011-08-17
ZA200606291B (en) 2008-02-27
EP1713776B1 (en) 2008-05-14
IL177101A (en) 2012-01-31
KR101160183B1 (ko) 2012-06-26
WO2005075428A1 (en) 2005-08-18
ES2306098T3 (es) 2008-11-01
AU2005210036A1 (en) 2005-08-18
AP2006003705A0 (en) 2006-08-31
US20070299106A1 (en) 2007-12-27
EA200601391A1 (ru) 2006-12-29
UA83875C2 (ru) 2008-08-26
AU2005210036B2 (en) 2010-12-23
JP2007519687A (ja) 2007-07-19
KR20070004597A (ko) 2007-01-09
CA2554049A1 (en) 2005-08-18
IL177101A0 (en) 2006-12-10
EP1713776A1 (en) 2006-10-25
MXPA06008596A (es) 2006-08-28
NO20063821L (no) 2006-08-28
CA2554049C (en) 2012-12-18
US7790894B2 (en) 2010-09-07
CN1910154A (zh) 2007-02-07
ATE395336T1 (de) 2008-05-15
NZ547614A (en) 2009-04-30
DE602005006744D1 (de) 2008-06-26
NO337253B1 (no) 2016-02-22
EA011572B1 (ru) 2009-04-28

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