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AP2015008844A0 - Heteroaromatic compounds and their use as dopamined1 ligands - Google Patents

Heteroaromatic compounds and their use as dopamined1 ligands

Info

Publication number
AP2015008844A0
AP2015008844A0 AP2015008844A AP2015008844A AP2015008844A0 AP 2015008844 A0 AP2015008844 A0 AP 2015008844A0 AP 2015008844 A AP2015008844 A AP 2015008844A AP 2015008844 A AP2015008844 A AP 2015008844A AP 2015008844 A0 AP2015008844 A0 AP 2015008844A0
Authority
AP
ARIPO
Prior art keywords
dopamined1
ligands
heteroaromatic compounds
heteroaromatic
compounds
Prior art date
Application number
AP2015008844A
Other languages
English (en)
Inventor
Lei Zhang
Bruce Nelson Rogers
Steven Victor O'neil
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51205521&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP2015008844(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of AP2015008844A0 publication Critical patent/AP2015008844A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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    • C—CHEMISTRY; METALLURGY
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
AP2015008844A 2013-06-27 2014-06-13 Heteroaromatic compounds and their use as dopamined1 ligands AP2015008844A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361840144P 2013-06-27 2013-06-27
PCT/IB2014/062217 WO2014207601A1 (en) 2013-06-27 2014-06-13 Heteroaromatic compounds and their use as dopamine d1 ligands

Publications (1)

Publication Number Publication Date
AP2015008844A0 true AP2015008844A0 (en) 2015-11-30

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ID=51205521

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Application Number Title Priority Date Filing Date
AP2015008844A AP2015008844A0 (en) 2013-06-27 2014-06-13 Heteroaromatic compounds and their use as dopamined1 ligands

Country Status (41)

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US (10) US9527831B2 (da)
EP (2) EP3013813B1 (da)
JP (1) JP6026024B2 (da)
KR (1) KR101781723B1 (da)
CN (1) CN105324376B (da)
AP (1) AP2015008844A0 (da)
AR (1) AR096748A1 (da)
AU (1) AU2014300673B2 (da)
BR (1) BR122023004130B1 (da)
CA (1) CA2916653C (da)
CL (1) CL2015003735A1 (da)
CR (1) CR20150634A (da)
CU (1) CU24334B1 (da)
DK (2) DK3013813T3 (da)
DO (1) DOP2015000302A (da)
EA (1) EA028637B1 (da)
EC (1) ECSP16003103A (da)
ES (2) ES2729630T3 (da)
FI (1) FI3421462T3 (da)
GT (1) GT201500350A (da)
HR (2) HRP20191163T1 (da)
HU (2) HUE062265T2 (da)
IL (1) IL242480B (da)
MA (1) MA38661A1 (da)
MD (1) MD20150122A2 (da)
MX (2) MX382599B (da)
NI (1) NI201500179A (da)
NZ (1) NZ713762A (da)
PE (1) PE20160664A1 (da)
PH (1) PH12015502502A1 (da)
PL (2) PL3421462T3 (da)
PT (2) PT3013813T (da)
RS (2) RS59018B1 (da)
SG (1) SG11201509186TA (da)
TN (1) TN2015000547A1 (da)
TR (1) TR201907981T4 (da)
TW (1) TWI508957B (da)
UA (1) UA112945C2 (da)
UY (1) UY35628A (da)
WO (1) WO2014207601A1 (da)
ZA (1) ZA201508252B (da)

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CA2916653C (en) 2013-06-27 2017-07-18 Pfizer Inc. Heteroaromatic compounds and their use as dopamine d1 ligands
KR20160142402A (ko) 2014-04-25 2016-12-12 화이자 인코포레이티드 도파민 d1 리간드로서 헤테로방향족 화합물 및 이의 용도
WO2015162515A1 (en) 2014-04-25 2015-10-29 Pfizer Inc. Heteroaromatic compounds and their use as dopamine d1 ligands
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KR102707502B1 (ko) 2015-10-14 2024-09-13 브리스톨-마이어스 스큅 컴퍼니 Apj 효능제로서의 2,4-디히드록시-니코틴아미드
WO2017103182A1 (en) 2015-12-18 2017-06-22 Janssen Pharmaceutica Nv Radiolabelled mglur2/3 pet ligands
US11045562B2 (en) 2015-12-18 2021-06-29 Janssen Pharmaceutica Nv Radiolabelled mGluR2/3 PET ligands
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TWI744301B (zh) 2016-03-24 2021-11-01 美商必治妥美雅史谷比公司 做為apj促效劑之6-羥基-4-側氧-1,4-二氫嘧啶-5-甲醯胺
UA123706C2 (uk) 2016-03-30 2021-05-19 Ісіхара Сангіо Кайся, Лтд. Сполука піридазинону або її сіль і гербіцид, що містить зазначену сполуку
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TW202222163A (zh) * 2020-08-14 2022-06-16 瑞士商先正達農作物保護公司 化學方法
CA3239783A1 (en) 2021-12-03 2023-06-08 Zuzana Przeczkova Solid state forms of tavapadon and processes for preparation thereof
CN118401513A (zh) * 2022-01-29 2024-07-26 苏州科睿思制药有限公司 他伐帕敦的晶型及其制备方法和用途
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