AP2006003790A0 - Pyrimidine derivatives for the treatment of abnormal cell growth - Google Patents

Pyrimidine derivatives for the treatment of abnormal cell growth

Info

Publication number: AP2006003790A0
Authority: AP; ARIPO
Prior art keywords: treatment; cell growth; abnormal cell; pyrimidine derivatives; pyrimidine
Prior art date: 2004-05-14

Application number

AP2006003790A

Other versions

AP2241A (en

Inventor

John Charles Kath

Michael Joseph Luzzio

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-05-14

Filing date

2005-05-02

Publication date

2006-10-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34966230&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP2006003790(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2005-05-02 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2006-10-31 Publication of AP2006003790A0 publication Critical patent/AP2006003790A0/en

2011-06-01 Application granted granted Critical

2011-06-01 Publication of AP2241A publication Critical patent/AP2241A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

AP2006003790A 2004-05-14 2005-05-02 Pyrimidine derivatives for the treatment of abnormal cell growth. AP2241A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US57131204P	2004-05-14	2004-05-14
PCT/IB2005/001201 WO2005111023A1 (en)	2004-05-14	2005-05-02	Pyrimidine derivatives for the treatment of abnormal cell growth

Publications (2)

Publication Number	Publication Date
AP2006003790A0 true AP2006003790A0 (en)	2006-10-31
AP2241A AP2241A (en)	2011-06-01

Family

ID=34966230

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AP2006003790A AP2241A (en)	2004-05-14	2005-05-02	Pyrimidine derivatives for the treatment of abnormal cell growth.

Country Status (27)

Country	Link
EP (1)	EP1751143A1 (en)
JP (1)	JP4099212B2 (en)
KR (1)	KR100886990B1 (en)
CN (2)	CN102127058A (en)
AP (1)	AP2241A (en)
AR (1)	AR049097A1 (en)
AU (2)	AU2005243397A1 (en)
BR (1)	BRPI0511138A (en)
CA (1)	CA2566707A1 (en)
CR (1)	CR8749A (en)
EA (1)	EA200601796A1 (en)
EC (1)	ECSP066997A (en)
GE (1)	GEP20104875B (en)
GT (1)	GT200500113A (en)
IL (1)	IL178828A0 (en)
MA (1)	MA28583B1 (en)
MX (1)	MXPA06011890A (en)
NL (2)	NL1029045C2 (en)
NO (1)	NO20064576L (en)
NZ (1)	NZ550448A (en)
PA (1)	PA8632601A1 (en)
PE (1)	PE20060240A1 (en)
TN (1)	TNSN06370A1 (en)
TW (1)	TWI303635B (en)
UY (1)	UY28894A1 (en)
WO (1)	WO2005111023A1 (en)
ZA (1)	ZA200608394B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1763514A2 (en) *	2004-05-18	2007-03-21	Rigel Pharmaceuticals, Inc.	Cycloalkyl substituted pyrimidinediamine compounds and their uses
US20070032514A1 (en) *	2005-07-01	2007-02-08	Zahn Stephan K	2,4-diamino-pyrimidines as aurora inhibitors
BRPI0620324A2 (en) *	2005-12-21	2011-11-08	Pfizer Prod Inc	pyrimidine derivatives, pharmaceutical composition and use thereof
CA2684447C (en) *	2007-04-18	2012-01-24	Pfizer Products Inc.	Sulfonyl amide derivatives for the treatment of abnormal cell growth
NZ582485A (en) *	2007-07-17	2012-05-25	Rigel Pharmaceuticals Inc	Cyclic amine substituted pyrimidinediamines as pkc inhibitors
WO2009071535A1 (en) *	2007-12-03	2009-06-11	Boehringer Ingelheim International Gmbh	Diaminopyridines for the treatment of diseases which are characterised by excessive or anomal cell proliferation
BRPI0908637B8 (en) *	2008-05-21	2021-05-25	Ariad Pharma Inc	compound and pharmaceutical composition thereof
US8410126B2 (en) *	2009-05-29	2013-04-02	Boehringer Ingelheim International Gmbh	Pyrimidine inhibitors of PKTK2
EP2464633A1 (en)	2009-08-14	2012-06-20	Boehringer Ingelheim International GmbH	Regioselective preparation of 2-amino-5-trifluoromethylpyrimidine derivatives
US8933227B2 (en)	2009-08-14	2015-01-13	Boehringer Ingelheim International Gmbh	Selective synthesis of functionalized pyrimidines
US20120244141A1 (en)	2010-09-28	2012-09-27	Boehringer Ingelheim International Gmbh	Stratification of cancer patients for susceptibility to therapy with PTK2 inhibitors
JPWO2014174745A1 (en) *	2013-04-26	2017-02-23	国立大学法人京都大学	Eg5 inhibitor
CN109608444B (en) *	2018-11-27	2022-02-11	中国药科大学	ERK inhibitor containing isoindolinone and preparation method and use thereof
CN111732548B (en) *	2020-06-11	2022-06-17	浙江大学	N2-carbamyl aromatic ring-2-aminopyrimidine derivatives and medical application thereof
WO2024140671A1 (en) *	2022-12-29	2024-07-04	南京昕瑞再生医药科技有限公司	Fused tricyclic derivative, pharmaceutical composition comprising same, and use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9721437D0 (en) *	1997-10-10	1997-12-10	Glaxo Group Ltd	Heteroaromatic compounds and their use in medicine
AR042586A1 (en)	2001-02-15	2005-06-29	Sugen Inc	3- (4-AMIDOPIRROL-2-ILMETILIDEN) -2-INDOLINONE AS INHIBITORS OF PROTEIN KINASE; YOUR PHARMACEUTICAL COMPOSITIONS; A METHOD FOR THE MODULATION OF THE CATALYTIC ACTIVITY OF PROTEINQUINASE; A METHOD TO TREAT OR PREVENT AN AFFECTION RELATED TO PROTEINQUINASE
WO2003030909A1 (en) *	2001-09-25	2003-04-17	Bayer Pharmaceuticals Corporation	2- and 4-aminopyrimidines n-substtituded by a bicyclic ring for use as kinase inhibitors in the treatment of cancer
UA80767C2 (en) *	2002-12-20	2007-10-25	Pfizer Prod Inc	Pyrimidine derivatives for the treatment of abnormal cell growth
DE60331479D1 (en) *	2002-12-20	2010-04-08	Pfizer Prod Inc	Pyrimidine derivatives for treating abnormal cell growth

2005
- 2005-05-02 BR BRPI0511138-2A patent/BRPI0511138A/en not_active IP Right Cessation
- 2005-05-02 NZ NZ550448A patent/NZ550448A/en not_active IP Right Cessation
- 2005-05-02 AP AP2006003790A patent/AP2241A/en active
- 2005-05-02 EP EP05732043A patent/EP1751143A1/en not_active Withdrawn
- 2005-05-02 AU AU2005243397A patent/AU2005243397A1/en not_active Abandoned
- 2005-05-02 MX MXPA06011890A patent/MXPA06011890A/en unknown
- 2005-05-02 CN CN2011100212904A patent/CN102127058A/en active Pending
- 2005-05-02 JP JP2007512557A patent/JP4099212B2/en not_active Expired - Lifetime
- 2005-05-02 EA EA200601796A patent/EA200601796A1/en unknown
- 2005-05-02 KR KR1020067023767A patent/KR100886990B1/en not_active Expired - Lifetime
- 2005-05-02 WO PCT/IB2005/001201 patent/WO2005111023A1/en not_active Ceased
- 2005-05-02 CA CA002566707A patent/CA2566707A1/en not_active Abandoned
- 2005-05-02 GE GEAP20059703A patent/GEP20104875B/en unknown
- 2005-05-02 CN CNA2005800155302A patent/CN1953974A/en active Pending
- 2005-05-11 TW TW094115237A patent/TWI303635B/en not_active IP Right Cessation
- 2005-05-11 PA PA20058632601A patent/PA8632601A1/en unknown
- 2005-05-12 UY UY28894A patent/UY28894A1/en not_active Application Discontinuation
- 2005-05-12 PE PE2005000534A patent/PE20060240A1/en not_active Application Discontinuation
- 2005-05-13 AR ARP050101969A patent/AR049097A1/en not_active Application Discontinuation
- 2005-05-13 NL NL1029045A patent/NL1029045C2/en not_active IP Right Cessation
- 2005-05-13 GT GT200500113A patent/GT200500113A/en unknown
2006
- 2006-05-19 NL NL1031845A patent/NL1031845C2/en not_active IP Right Cessation
- 2006-10-06 ZA ZA200608394A patent/ZA200608394B/en unknown
- 2006-10-09 NO NO20064576A patent/NO20064576L/en not_active Application Discontinuation
- 2006-10-23 IL IL178828A patent/IL178828A0/en unknown
- 2006-11-13 TN TNP2006000370A patent/TNSN06370A1/en unknown
- 2006-11-13 EC EC2006006997A patent/ECSP066997A/en unknown
- 2006-11-13 CR CR8749A patent/CR8749A/en not_active Application Discontinuation
- 2006-11-14 MA MA29452A patent/MA28583B1/en unknown
2009
- 2009-11-13 AU AU2009238255A patent/AU2009238255A1/en not_active Ceased

Also Published As

Publication number	Publication date
EP1751143A1 (en)	2007-02-14
ZA200608394B (en)	2008-05-28
AU2009238255A1 (en)	2009-12-03
JP2007537234A (en)	2007-12-20
GEP20104875B (en)	2010-01-11
TWI303635B (en)	2008-12-01
NO20064576L (en)	2006-11-07
TW200539871A (en)	2005-12-16
KR100886990B1 (en)	2009-03-04
PE20060240A1 (en)	2006-04-01
CN1953974A (en)	2007-04-25
WO2005111023A1 (en)	2005-11-24
MA28583B1 (en)	2007-05-02
NL1031845C2 (en)	2006-11-23
CR8749A (en)	2006-12-05
EA200601796A1 (en)	2007-04-27
NL1029045A1 (en)	2005-11-15
TNSN06370A1 (en)	2008-02-22
KR20070012477A (en)	2007-01-25
MXPA06011890A (en)	2006-12-14
IL178828A0 (en)	2007-03-08
CN102127058A (en)	2011-07-20
NZ550448A (en)	2010-11-26
AR049097A1 (en)	2006-06-28
ECSP066997A (en)	2007-02-28
BRPI0511138A (en)	2007-11-27
AU2005243397A1 (en)	2005-11-24
GT200500113A (en)	2006-01-10
NL1029045C2 (en)	2006-06-02
JP4099212B2 (en)	2008-06-11
NL1031845A1 (en)	2006-07-31
CA2566707A1 (en)	2005-11-24
UY28894A1 (en)	2005-12-30
PA8632601A1 (en)	2006-06-02
AP2241A (en)	2011-06-01

Publication	Publication Date	Title
IL191555A0 (en)	2008-12-29	Pyrimidine derivatives for the treatment of abnormal cell growth
IL172047A0 (en)	2009-02-11	Pyrimidine derivatives for the treatment of abnormal cell growth
AU2003288603A8 (en)	2004-07-14	Pyrimidine derivates for the treatment of abnormal cell growth
TWI369205B (en)	2012-08-01	Sulfonyl amide derivatives for the treatment of abnormal cell growth
IL191471A0 (en)	2009-08-03	Method of treating abnormal cell growth
IL161908A0 (en)	2005-11-20	Quinazoline derivatives for the treatment of abnormal cell growth
IL190135A0 (en)	2008-08-07	Process for the preparation of pyrimidinedione derivatives
IL181305A0 (en)	2007-07-04	Combinations for the treatment of diseases involving cell proliferation
IL185498A0 (en)	2008-01-06	Pyrimidine derivatives for treatment of hyperproliferative disorders
IL176942A0 (en)	2006-12-10	Imidazolo-5-yl-2-anilinopyrimidines as agents for the inhibition of cell proliferation
AP2006003790A0 (en)	2006-10-31	Pyrimidine derivatives for the treatment of abnormal cell growth
IL177232A0 (en)	2006-12-10	Heteroarylaminopyrazole derivatives useful for the treatment of diabetes
PL1763517T3 (en)	2011-10-31	Pyrimidine derivatives as 11beta-hsd1 inhibitors
PL377686A1 (en)	2006-02-06	4-anilino quinazoline derivatives for the treatment of abnormal cell growth
ZA200804777B (en)	2009-03-25	Method of treating abnormal cell growth
PL1959957T3 (en)	2012-12-31	Pyrimidylaminobenzamide derivatives for the treatment of neurofibromatosis
EP1750698A4 (en)	2010-06-02	5-anilino-4-heteroarylpyrazole derivatives useful for the treatment of diabetes
EP1901770A4 (en)	2010-11-03	Methods for treatment of growth disorders
ZA200608015B (en)	2008-12-31	Heteroarylaminopyrazole derivatives useful for the treatment of diabetes
HK1100928A (en)	2007-10-05	Imidazolo-5-yl-2-anilinopyrimidines as agents for the inhibition of cell proliferation
AU2006906546A0 (en)	2006-12-07	Use of lenght-modifiable electrode carriers particularly for cochlear implants
GB0516085D0 (en)	2005-09-14	Treatment of viable cells