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AP2004003021A0 - Vectors, constructs and transgenic plants for HPV-11 and HPV-16 L1 capsid protein. - Google Patents

Vectors, constructs and transgenic plants for HPV-11 and HPV-16 L1 capsid protein.

Info

Publication number
AP2004003021A0
AP2004003021A0 APAP/P/2004/003021A AP2004003021A AP2004003021A0 AP 2004003021 A0 AP2004003021 A0 AP 2004003021A0 AP 2004003021 A AP2004003021 A AP 2004003021A AP 2004003021 A0 AP2004003021 A0 AP 2004003021A0
Authority
AP
ARIPO
Prior art keywords
hpv
cells
constructs
vectors
transgenic plants
Prior art date
Application number
APAP/P/2004/003021A
Inventor
Arvind Devshi Varsani
Edward Peter Rybicki
Anna-Lise Williamson
Original Assignee
Univ Cape Town
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Cape Town filed Critical Univ Cape Town
Publication of AP2004003021A0 publication Critical patent/AP2004003021A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5156—Animal cells expressing foreign proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20023—Virus like particles [VLP]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Vectors and/or constructs of human papillomavirus genes are used in transforming host cells, such as bacteria, yeast cells, fungal cells, insect cells, mammalian cells and plant cells. The host cells are cultivated under conditions which permit spotaeousamly of at least one protein fragment of a protein encoded by the vector and/or gene construct into an immunogenic-response elicitig virus-like particle directed against human papillomavirus.
APAP/P/2004/003021A 2001-08-31 2002-08-30 Vectors, constructs and transgenic plants for HPV-11 and HPV-16 L1 capsid protein. AP2004003021A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ZA200107226 2001-08-31
PCT/IB2002/003532 WO2003018624A1 (en) 2001-08-31 2002-08-30 Vectors, constructs, and transgenic plants for hpv-11 and hpv-16 l1 capsid protein

Publications (1)

Publication Number Publication Date
AP2004003021A0 true AP2004003021A0 (en) 2004-06-30

Family

ID=25589294

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/2004/003021A AP2004003021A0 (en) 2001-08-31 2002-08-30 Vectors, constructs and transgenic plants for HPV-11 and HPV-16 L1 capsid protein.

Country Status (4)

Country Link
CN (1) CN1290859C (en)
AP (1) AP2004003021A0 (en)
WO (1) WO2003018624A1 (en)
ZA (1) ZA200402504B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1883701B1 (en) * 2005-04-29 2012-01-18 University of Cape Town Expression of viral proteins in plants
WO2006065166A1 (en) * 2005-07-26 2006-06-22 Obschestvo S Ogranichennoi Otvetstvennostyu 'rusgen' Protein l1 and protein e7 peptide-based composition for treating and preventing a human papillomaviral infection
CN100392084C (en) * 2006-03-13 2008-06-04 曾毅 Recombinant adenovirus containing codon-optimized HPV16L1 gene
CN1869215B (en) * 2006-05-19 2012-07-04 长春百克生物科技股份公司 Method of preparing virus sample parlicle of human papillomavirus
CN101153280B (en) * 2006-09-29 2015-08-19 厦门大学 The method of purifying human papilloma virus advanced protein L1 from prokaryotic organism
BRPI0811016B1 (en) 2007-04-29 2021-09-21 Xiamen Innovax Biotech Co., Ltd. LI TRUNCATE PROTEIN FROM HUMAN PAPILOMA VIRUS TYPE 16
DK2147926T3 (en) * 2007-04-29 2016-11-28 Beijing Wantai Biological Pharmacy Entpr Co Ltd Truncated human papillomavirus type 18 L1 protein
US9533035B2 (en) 2007-05-29 2017-01-03 Xiamen University Truncated L1 protein of human papillomavirus type 11
CN102321635B (en) * 2011-09-02 2014-02-26 中国农业科学院生物技术研究所 Preparation method and product of human papillomavirus empty capsid particles
CN114539363B (en) * 2020-11-26 2023-12-01 中国医学科学院基础医学研究所 C-terminal modified human papilloma virus 11 type L1 protein and application thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10055545A1 (en) * 2000-11-09 2002-07-25 Deutsches Krebsforsch HPV 16-L1 and HPV 16-L2 encoding DNA sequences optimized for expression in eukaryotes

Also Published As

Publication number Publication date
WO2003018624A1 (en) 2003-03-06
CN1290859C (en) 2006-12-20
CN1578787A (en) 2005-02-09
ZA200402504B (en) 2005-06-29

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