[go: up one dir, main page]

AP2001002093A0 - Dry powder active agent pulmonary delivery - Google Patents

Dry powder active agent pulmonary delivery

Info

Publication number
AP2001002093A0
AP2001002093A0 AP2001002093A AP2001002093A AP2001002093A0 AP 2001002093 A0 AP2001002093 A0 AP 2001002093A0 AP 2001002093 A AP2001002093 A AP 2001002093A AP 2001002093 A AP2001002093 A AP 2001002093A AP 2001002093 A0 AP2001002093 A0 AP 2001002093A0
Authority
AP
ARIPO
Prior art keywords
active agent
dry powder
pulmonary delivery
powder active
agent pulmonary
Prior art date
Application number
AP2001002093A
Other versions
AP1374A (en
Original Assignee
Inhale Therapeutic Syst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inhale Therapeutic Syst filed Critical Inhale Therapeutic Syst
Publication of AP2001002093A0 publication Critical patent/AP2001002093A0/en
Application granted granted Critical
Publication of AP1374A publication Critical patent/AP1374A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Inorganic Chemistry (AREA)
  • Oncology (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
APAP/P/2001/002093A 1998-09-14 1999-09-13 Aerosolizable particles resistant to hygroscopic growth. AP1374A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10016398P 1998-09-14 1998-09-14
PCT/US1999/021109 WO2000015262A1 (en) 1998-09-14 1999-09-13 Dry powder active agent pulmonary delivery

Publications (2)

Publication Number Publication Date
AP2001002093A0 true AP2001002093A0 (en) 2001-03-31
AP1374A AP1374A (en) 2005-02-28

Family

ID=22278404

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/2001/002093A AP1374A (en) 1998-09-14 1999-09-13 Aerosolizable particles resistant to hygroscopic growth.

Country Status (44)

Country Link
EP (1) EP1117442A1 (en)
JP (1) JP2002524535A (en)
KR (1) KR20010075063A (en)
CN (1) CN1317977A (en)
AP (1) AP1374A (en)
AR (1) AR022090A1 (en)
AU (1) AU753014B2 (en)
BG (1) BG105430A (en)
BR (1) BR9913722A (en)
CA (1) CA2343920A1 (en)
CO (1) CO5130023A1 (en)
CZ (1) CZ2001829A3 (en)
DZ (1) DZ2892A1 (en)
EA (1) EA003476B1 (en)
EE (1) EE200100151A (en)
GE (1) GEP20043257B (en)
GT (1) GT199900156A (en)
HK (1) HK1042231A1 (en)
HN (1) HN1999000159A (en)
HR (1) HRP20010189A2 (en)
HU (1) HUP0103837A3 (en)
ID (1) ID28845A (en)
IL (2) IL141562A0 (en)
IS (1) IS5878A (en)
LT (1) LT4897B (en)
LV (1) LV12658B (en)
MA (1) MA25590A1 (en)
MY (1) MY129282A (en)
NO (1) NO20011251L (en)
NZ (1) NZ510168A (en)
OA (1) OA11781A (en)
PA (1) PA8481901A1 (en)
PE (1) PE20001061A1 (en)
PL (1) PL195574B1 (en)
SA (1) SA99200718B1 (en)
SK (1) SK3442001A3 (en)
TN (1) TNSN99173A1 (en)
TR (1) TR200101182T2 (en)
TW (1) TWI226248B (en)
UA (1) UA76085C2 (en)
UY (1) UY25711A1 (en)
WO (1) WO2000015262A1 (en)
YU (1) YU24201A (en)
ZA (1) ZA200101995B (en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6956021B1 (en) 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
WO2000075281A2 (en) 1999-06-09 2000-12-14 University Technology Corporation Supercritical fluid-assisted nebulization and bubble drying
US6475468B2 (en) * 2001-02-15 2002-11-05 Aeropharm Technology Incorporated Modulated release particles for aerosol delivery
EP1392262A1 (en) * 2001-05-24 2004-03-03 Alexza Molecular Delivery Corporation Delivery of drug esters through an inhalation route
EG24184A (en) 2001-06-15 2008-10-08 Otsuka Pharma Co Ltd Dry powder inhalation system for transpulmonary
JP4368198B2 (en) 2001-11-20 2009-11-18 アルカーメス,インコーポレイテッド Improved particulate composition for pulmonary delivery
US7759506B2 (en) 2002-02-25 2010-07-20 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
EA200401111A1 (en) 2002-02-25 2005-02-24 Диффьюжн Фармасьютикалз Ллс TRANS-CAROTINOID BIPOLAR SALTS AND THEIR APPLICATION
WO2004004798A2 (en) * 2002-07-03 2004-01-15 The Brigham And Women's Hospital, Inc. Central airway administration for systemic delivery of therapeutics
ATE353633T1 (en) * 2002-12-19 2007-03-15 Pharmacia Corp NON-HYGROSCOPIC FORMULATION CONTAINING A HYGROSCOPIC ACTIVE INGREDIENT
DE10338403A1 (en) * 2003-08-18 2005-03-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powder formulation containing the CGRP antagonist 1- [N 2 - [3,5-dibromo-N - [[4- (3,4-dihydro-2 (1 H) -oxoquinazolin-3-yl] -1-piperidinyl] carbonyl] -D-tyrosyl] -L-lysyl] -4- (4-pyrindinyl) piperazine, process for its preparation and its use as inhalant
GB0327723D0 (en) * 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
US20070020299A1 (en) 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
CN101098678A (en) 2004-04-23 2008-01-02 锡德克斯公司 DPI formulations containing sulfoalkyl ether cyclodextrins
MX2007010359A (en) 2005-02-24 2008-04-04 Diffusion Pharmaceuticals Llc Trans carotenoids, their synthesis, formulation and uses.
JPWO2006095788A1 (en) * 2005-03-09 2008-08-14 小野薬品工業株式会社 Particles and formulations containing the particles
PL2952197T3 (en) 2005-10-26 2017-09-29 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
US7629331B2 (en) 2005-10-26 2009-12-08 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
US20100269819A1 (en) * 2006-08-14 2010-10-28 Sievers Robert E Human Powered Dry Powder Inhaler and Dry Powder Inhaler Compositions
US20100093875A1 (en) * 2006-10-25 2010-04-15 Dainippon Sumitomo Pharma Co., Ltd. Granular preparation prevented from caking
EP1925295A1 (en) * 2006-11-22 2008-05-28 Boehringer Ingelheim Pharma GmbH & Co. KG Stable powder formulation containing a new antichinolinergic agent
CA2683760C (en) 2007-04-13 2015-05-19 Diffusion Pharmaceuticals Llc Use of bipolar trans carotenoids as a pretreatment and in the treatment of peripheral vascular disease
US12370352B2 (en) 2007-06-28 2025-07-29 Cydex Pharmaceuticals, Inc. Nasal and ophthalmic delivery of aqueous corticosteroid solutions
US8206751B2 (en) 2007-10-31 2012-06-26 Diffusion Pharmaceuticals Llc Class of therapeutics that enhance small molecule diffusion
CN105770882A (en) 2009-05-20 2016-07-20 Aeras全球Tb疫苗基金会 Stable, spray dried, immunogenic, viral compositions
US10130689B2 (en) 2009-06-22 2018-11-20 Diffusion Pharmaceuticals Llc Diffusion enhancing compounds and their use alone or with thrombolytics
WO2011152869A1 (en) 2010-06-02 2011-12-08 Diffusion Pharmaceuticals Llc Oral formulations of bipolar trans carotenoids
CA2866230C (en) 2012-05-03 2020-08-18 Janssen R&D Ireland Polyinosinic-polycytidylic acid (poly (i:c)) formulations for the treatment of upper respiratory tract infections
BR112015010601B1 (en) * 2012-11-09 2022-07-19 Civitas Therapeutics, Inc. PHARMACEUTICAL COMPOSITION AND USE OF THE COMPOSITION
WO2015042352A1 (en) * 2013-09-20 2015-03-26 Virginia Commonwealth University Delivery of particles using hygroscopic excipients
CA2965759C (en) 2014-10-31 2023-12-12 Glaxosmithkline Intellectual Property Development Limited Powdered polypeptides with decreased disulfide impurities comprising divalent cationic materials
CN109152839A (en) 2016-03-24 2019-01-04 扩散药品有限公司 Use of bipolar trans carotenoids in conjunction with chemotherapy and radiation therapy in the treatment of cancer
US20220378727A1 (en) * 2021-05-14 2022-12-01 The University Of Hong Kong Dry powder formulations of tamibarotene for pulmonary and intranasal delivery

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3155573A (en) * 1958-05-06 1964-11-03 Benger Lab Ltd Inhalant composition and method of making same
CA2115065C (en) * 1992-06-12 2000-10-03 Kiyoyuki Sakon Ultrafine particle powder for inhalation and method for production thereof
US6524557B1 (en) * 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
US5874064A (en) 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
EP0954282B1 (en) * 1997-01-16 2005-01-19 Massachusetts Institute Of Technology Preparation of particles for inhalation
US6086376A (en) * 1998-01-30 2000-07-11 Rtp Pharma Inc. Dry aerosol suspension of phospholipid-stabilized drug microparticles in a hydrofluoroalkane propellant

Also Published As

Publication number Publication date
NO20011251L (en) 2001-04-17
TR200101182T2 (en) 2001-09-21
TNSN99173A1 (en) 2005-11-10
AR022090A1 (en) 2002-09-04
ID28845A (en) 2001-07-05
EE200100151A (en) 2002-06-17
HUP0103837A2 (en) 2002-05-29
HRP20010189A2 (en) 2005-04-30
TWI226248B (en) 2005-01-11
CN1317977A (en) 2001-10-17
SK3442001A3 (en) 2001-11-06
SA99200718B1 (en) 2006-11-04
PL195574B1 (en) 2007-10-31
CA2343920A1 (en) 2000-03-23
JP2002524535A (en) 2002-08-06
HK1042231A1 (en) 2002-08-09
EA003476B1 (en) 2003-06-26
PL346768A1 (en) 2002-02-25
EP1117442A1 (en) 2001-07-25
IL141562A0 (en) 2002-03-10
BR9913722A (en) 2001-05-29
CZ2001829A3 (en) 2001-09-12
NZ510168A (en) 2003-09-26
AP1374A (en) 2005-02-28
MA25590A1 (en) 2002-12-31
OA11781A (en) 2005-07-26
HUP0103837A3 (en) 2002-11-28
GT199900156A (en) 2001-03-07
AU6039799A (en) 2000-04-03
UA76085C2 (en) 2006-07-17
AU753014B2 (en) 2002-10-03
LV12658B (en) 2001-09-20
CO5130023A1 (en) 2002-02-27
IS5878A (en) 2001-03-05
NO20011251D0 (en) 2001-03-13
MY129282A (en) 2007-03-30
PE20001061A1 (en) 2000-10-08
UY25711A1 (en) 1999-11-17
PA8481901A1 (en) 2002-04-25
DZ2892A1 (en) 2003-12-15
EA200100300A1 (en) 2001-10-22
GEP20043257B (en) 2004-06-25
BG105430A (en) 2001-12-29
LT4897B (en) 2002-02-25
LV12658A (en) 2001-05-20
IL141562A (en) 2007-07-24
WO2000015262A1 (en) 2000-03-23
KR20010075063A (en) 2001-08-09
LT2001021A (en) 2001-11-26
HN1999000159A (en) 1999-11-11
YU24201A (en) 2003-08-29
ZA200101995B (en) 2002-03-11

Similar Documents

Publication Publication Date Title
AP2001002093A0 (en) Dry powder active agent pulmonary delivery
EP0927025A4 (en) Liposome encapsulated active agent dry powder composition
HUP0001799A3 (en) Dry powder inhaler
HUP0100848A3 (en) Aerosolized active agent delivery
EP1307256A4 (en) Dry powder inhaler
SI1294421T1 (en) Dry Powder Inhaler
HUP9903819A3 (en) Dry powder inhaler
PL360118A1 (en) Continuous dry powder inhaler
IL137472A0 (en) Microparticle inhalation formulations
IL149362A0 (en) Aerosol composition comprising formoterol
DE60035911D1 (en) dry powder inhaler
HUP0104483A3 (en) Fungicidal active substance combinations and use thereof
PL316903A1 (en) Dry powder inhaler
SI1397174T1 (en) Powder formulation disintegrating system and dry powder inhalers
PL341820A1 (en) Coating composition in the form of dry powder
GB9916316D0 (en) Dry powder compositions
HUP0203611A3 (en) 14,15-beta-methylene substituted androgens and their use for preparation of the medicaments
GB9719093D0 (en) Improvements to dry powder inhalers
GB0003935D0 (en) Formulation for dry powder inhaler
CZ20021359A3 (en) Preparation for fighting dry rots
AU1752601A (en) Dry powder inhaler
HUP0105425A3 (en) Suspo-emulsion formulation
GB9927812D0 (en) Improved pesticide formulation
HK1036941A (en) Pulmonary delivery of active agents
AU129749S (en) Dry powder inhaler