OA08937A - Procédé d'inhibition d'un virus. - Google Patents
Procédé d'inhibition d'un virus.Info
- Publication number
- OA08937A OA08937A OA59494A OA59494A OA08937A OA 08937 A OA08937 A OA 08937A OA 59494 A OA59494 A OA 59494A OA 59494 A OA59494 A OA 59494A OA 08937 A OA08937 A OA 08937A
- Authority
- OA
- OAPI
- Prior art keywords
- dideoxy
- imino
- methyl
- ribitol
- fucitol
- Prior art date
Links
- 230000002401 inhibitory effect Effects 0.000 title abstract 2
- 241000700605 Viruses Species 0.000 title 1
- OQEBIHBLFRADNM-LMVFSUKVSA-N (2s,3s,4r)-2-(hydroxymethyl)pyrrolidine-3,4-diol Chemical compound OC[C@@H]1NC[C@@H](O)[C@H]1O OQEBIHBLFRADNM-LMVFSUKVSA-N 0.000 abstract 1
- RVNSAAIWCWTCTJ-ARQDHWQXSA-N (2s,3s,4r)-2-[(1s)-1,2-dihydroxyethyl]pyrrolidine-3,4-diol Chemical compound OC[C@@H](O)[C@@H]1NC[C@@H](O)[C@H]1O RVNSAAIWCWTCTJ-ARQDHWQXSA-N 0.000 abstract 1
- OQEBIHBLFRADNM-MROZADKFSA-N 1,4-Dideoxy-1,4-imino-D-ribitol Chemical compound OC[C@H]1NC[C@H](O)[C@@H]1O OQEBIHBLFRADNM-MROZADKFSA-N 0.000 abstract 1
- OQEBIHBLFRADNM-YUPRTTJUSA-N 2-hydroxymethyl-pyrrolidine-3,4-diol Chemical compound OC[C@@H]1NC[C@H](O)[C@H]1O OQEBIHBLFRADNM-YUPRTTJUSA-N 0.000 abstract 1
- OQEBIHBLFRADNM-UHFFFAOYSA-N D-iminoxylitol Natural products OCC1NCC(O)C1O OQEBIHBLFRADNM-UHFFFAOYSA-N 0.000 abstract 1
- LXBIFEVIBLOUGU-UHFFFAOYSA-N Deoxymannojirimycin Natural products OCC1NCC(O)C(O)C1O LXBIFEVIBLOUGU-UHFFFAOYSA-N 0.000 abstract 1
- 241000725303 Human immunodeficiency virus Species 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002391 heterocyclic compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms
- C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Compounds Of Unknown Constitution (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13621987A | 1987-12-21 | 1987-12-21 | |
| US07/249,144 US4999360A (en) | 1987-12-21 | 1988-09-26 | Method of inhibiting virus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| OA08937A true OA08937A (fr) | 1989-10-31 |
Family
ID=26834131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| OA59494A OA08937A (fr) | 1987-12-21 | 1988-12-20 | Procédé d'inhibition d'un virus. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4999360A (fr) |
| EP (1) | EP0322395B1 (fr) |
| JP (1) | JP2538014B2 (fr) |
| KR (1) | KR910009994B1 (fr) |
| AT (1) | ATE87206T1 (fr) |
| AU (1) | AU607834B2 (fr) |
| CA (1) | CA1316929C (fr) |
| DE (1) | DE3879653T2 (fr) |
| DK (1) | DK175113B1 (fr) |
| FI (1) | FI93210C (fr) |
| IE (1) | IE63095B1 (fr) |
| IL (1) | IL88742A (fr) |
| NO (1) | NO172340C (fr) |
| NZ (1) | NZ227410A (fr) |
| OA (1) | OA08937A (fr) |
| PT (1) | PT89267B (fr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE68925940T2 (de) * | 1988-11-03 | 1996-10-24 | Searle & Co | Dideoxy-L-arabinitol Derivate als Antivirus-Verbindungen |
| US4894388A (en) * | 1988-12-22 | 1990-01-16 | Monsanto Company | Glycosidase inhibitors and use thereof |
| US5100797A (en) * | 1989-06-27 | 1992-03-31 | Monsanto Company | Fucosidase inhibitors |
| US5043273A (en) * | 1989-08-17 | 1991-08-27 | Monsanto Company | Phosphorylated glycosidase inhibitor prodrugs |
| IT1239950B (it) * | 1990-03-28 | 1993-11-27 | Zambon Spa | Processo per la preparazione di composti con attivita' analgesica centrale |
| US5252587A (en) * | 1990-04-27 | 1993-10-12 | Merrell Dow Pharmaceuticals, Inc. | N-derivatives of 1-deoxy nojirimycin |
| US5536732A (en) * | 1990-04-27 | 1996-07-16 | Merrell Pharmaceuticals Inc. | N-derivatives of 1-deoxy nojirimycin |
| US5290948A (en) * | 1990-09-17 | 1994-03-01 | Mcneilab, Inc. | Process for producing polyhydroxylated piperidines and pyrrolidines and compounds thereof |
| GB9026271D0 (en) * | 1990-12-03 | 1991-01-16 | Alphey Thomas J W | Control of parasitic nematodes(a) |
| US5258518A (en) * | 1992-04-01 | 1993-11-02 | G. D. Searle & Co. | 2-substituted tertiary carbinol derivatives of deoxynojirimycin |
| US5451679A (en) * | 1994-03-08 | 1995-09-19 | G. D. Searle & Co. | 2-chloro and 2-bromo derivatives of 1,5-iminosugars |
| AU724003B2 (en) * | 1995-09-08 | 2000-09-07 | Novo Nordisk A/S | 2-alkylpyrrolidines |
| CN102399228B (zh) * | 2010-09-08 | 2013-10-16 | 中国科学院成都生物研究所 | N-烷基多羟基哌啶衍生物的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1555654A (en) * | 1977-06-25 | 1979-11-14 | Exxon Research Engineering Co | Agricultural burner apparatus |
| US4065562A (en) * | 1975-12-29 | 1977-12-27 | Nippon Shinyaku Co., Ltd. | Method and composition for reducing blood glucose levels |
| DE3038901A1 (de) * | 1980-10-15 | 1982-05-06 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von n-substituierten derivaten des 1-desoxynojirimycins |
| DE3507019A1 (de) * | 1985-02-28 | 1986-08-28 | Bayer Ag, 5090 Leverkusen | Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung |
| WO1987003903A1 (fr) * | 1985-12-23 | 1987-07-02 | Fred Hutchinson Cancer Research Center | Regulation de la replication, de l'infection et de la pathogenese retrovirales |
-
1988
- 1988-09-26 US US07/249,144 patent/US4999360A/en not_active Expired - Lifetime
- 1988-12-20 PT PT89267A patent/PT89267B/pt active IP Right Revival
- 1988-12-20 NO NO885655A patent/NO172340C/no not_active IP Right Cessation
- 1988-12-20 NZ NZ227410A patent/NZ227410A/en unknown
- 1988-12-20 FI FI885880A patent/FI93210C/fi not_active IP Right Cessation
- 1988-12-20 KR KR1019880017028A patent/KR910009994B1/ko not_active Expired
- 1988-12-20 IL IL88742A patent/IL88742A/xx not_active IP Right Cessation
- 1988-12-20 IE IE379488A patent/IE63095B1/en not_active IP Right Cessation
- 1988-12-20 AT AT88870192T patent/ATE87206T1/de not_active IP Right Cessation
- 1988-12-20 EP EP88870192A patent/EP0322395B1/fr not_active Expired - Lifetime
- 1988-12-20 CA CA000586466A patent/CA1316929C/fr not_active Expired - Fee Related
- 1988-12-20 DK DK198807081A patent/DK175113B1/da not_active IP Right Cessation
- 1988-12-20 OA OA59494A patent/OA08937A/fr unknown
- 1988-12-20 DE DE88870192T patent/DE3879653T2/de not_active Expired - Fee Related
- 1988-12-20 JP JP63321868A patent/JP2538014B2/ja not_active Expired - Fee Related
- 1988-12-20 AU AU27068/88A patent/AU607834B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE3879653T2 (de) | 1993-10-14 |
| AU2706888A (en) | 1989-06-22 |
| FI93210C (fi) | 1995-03-10 |
| PT89267B (pt) | 1993-12-31 |
| PT89267A (pt) | 1989-12-29 |
| NO885655D0 (no) | 1988-12-20 |
| ATE87206T1 (de) | 1993-04-15 |
| DK708188A (da) | 1989-06-22 |
| KR890009389A (ko) | 1989-08-01 |
| KR910009994B1 (ko) | 1991-12-10 |
| IE63095B1 (en) | 1995-03-22 |
| EP0322395A1 (fr) | 1989-06-28 |
| JPH01230517A (ja) | 1989-09-14 |
| IE883794L (en) | 1989-06-21 |
| NO172340B (no) | 1993-03-29 |
| US4999360A (en) | 1991-03-12 |
| IL88742A (en) | 1993-08-18 |
| DK175113B1 (da) | 2004-06-07 |
| FI885880A0 (fi) | 1988-12-20 |
| NO172340C (no) | 1993-07-07 |
| NO885655L (no) | 1989-06-22 |
| DK708188D0 (da) | 1988-12-20 |
| FI885880L (fi) | 1989-06-22 |
| NZ227410A (en) | 1991-06-25 |
| DE3879653D1 (de) | 1993-04-29 |
| EP0322395B1 (fr) | 1993-03-24 |
| FI93210B (fi) | 1994-11-30 |
| AU607834B2 (en) | 1991-03-14 |
| CA1316929C (fr) | 1993-04-27 |
| IL88742A0 (en) | 1989-07-31 |
| JP2538014B2 (ja) | 1996-09-25 |
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