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NZ786935B2 - Inhaler for use with a compliance monitor - Google Patents

Inhaler for use with a compliance monitor Download PDF

Info

Publication number
NZ786935B2
NZ786935B2 NZ786935A NZ78693520A NZ786935B2 NZ 786935 B2 NZ786935 B2 NZ 786935B2 NZ 786935 A NZ786935 A NZ 786935A NZ 78693520 A NZ78693520 A NZ 78693520A NZ 786935 B2 NZ786935 B2 NZ 786935B2
Authority
NZ
New Zealand
Prior art keywords
inhaler
orifice
inhaler according
housing
channel
Prior art date
Application number
NZ786935A
Other versions
NZ786935A (en
Inventor
Roger Clarke
Darryl Cotton
John Deamer
Andreas Meliniotis
Original Assignee
Vectura Delivery Devices Limited
Filing date
Publication date
Application filed by Vectura Delivery Devices Limited filed Critical Vectura Delivery Devices Limited
Priority claimed from PCT/EP2020/082422 external-priority patent/WO2021099324A1/en
Publication of NZ786935A publication Critical patent/NZ786935A/en
Publication of NZ786935B2 publication Critical patent/NZ786935B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/003—Particle size control by passing the aerosol trough sieves or filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A61M15/0026—Hinged caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0035—Piercing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0051—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/008—Electronic counters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0027—Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/0007—Special media to be introduced, removed or treated introduced into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow

Abstract

Dry powder inhalers provide an attractive method for administering medicaments, for example to treat local diseases of the airway or delivery drugs to the bloodstream via the lungs. There is increasing interest in monitoring patient adherence and compliance. Prior art problems include additional components which the user must connect correctly which could discourage patients from using the compliance monitor. A dry powder inhaler is provided. The inhaler (1) is adapted for detachably mounting a compliance monitor (40) having a pressure sensor (42). The inhaler has a housing comprising first and second shell parts (2, 3), and a mouthpiece (5) which defines an inhalation passage. An external surface of the housing has an orifice (11). A conduit (10) from the orifice to the inhalation passage is formed by a channel (31) in one of the shell parts and a corresponding channel cover in the other shell part. When the compliance monitor is mounted on the housing, the pressure sensor is adjacent to the orifice and is in fluid communication with the inhalation passage via the conduit.

Claims (17)

WE CLAIM:
1. A dry powder inhaler adapted for detachably mounting a compliance monitor having a pressure sensor, the inhaler comprising: • a housing comprising first and second shell parts, • a mouthpiece which s an inhalation passage, • an orifice in an external surface of the housing, and • a conduit from the orifice to the inhalation passage which is formed by a channel in the second shell part and a corresponding channel cover in the first shell part, for ting the pressure sensor to the inhalation passage.
2. An r according to claim 1 wherein the first and second shell parts are moulded plastic parts.
3. An inhaler according to claim 1 or claim 2, wherein the conduit has a cross-sectional area of less than 5 mm2.
4. An inhaler according to claim 3, wherein the cross-sectional area is less than 2 mm2.
5. An inhaler according to claim 4, wherein the cross-sectional area is about 1 mm2.
6. An inhaler according to any of claims 1 to 5, wherein the channel has a ledge on each side.
7. An inhaler according to claim 6, n the channel cover is formed as a protrusion.
8. An inhaler according to claim 7 wherein the protrusion and ledges are welded together along their length but are not welded er at the external surface of the housing.
9. An inhaler according to claim 8 wherein the height of the sion is greater than the depth of the ledges and the width of the protrusion is less than the width of the channel and ledges.
10. An inhaler ing to any of claims 1 to 9 wherein the e is formed at the join between the shell parts. AH26(43577055_1):BJM
11. An inhaler ing to any of claims 6 to 9, wherein the orifice is formed entirely within the second shell part.
12. An inhaler according to claim 11, wherein the channel has a step near the orifice so that its depth is increased.
13. An inhaler according to claim 12 wherein the channel has an end ledge adjacent to the orifice on the inside of the second shell part, wherein the end ledge connects the ledges on each side of the channel.
14. An inhaler according to any of claims 1 to 13 which ses a tment for a blister strip having a plurality of blisters which contain powdered medicament for tion, an indexing mechanism for moving the blister strip, a r which is mounted on the underside of the mouthpiece, and an actuator which drives the indexing mechanism to move one or more blisters into alignment with the r and which then moves the iece relative to the housing so that the r pierces the aligned blister(s), wherein • the mouthpiece comprises a sleeve, • the housing comprises a chimney which fits closely inside the sleeve, • the t extends through the chimney so that, when the mouthpiece is in the piercing position, the conduit is in fluid communication with the inhalation passage.
15. An inhaler according to any of claims 1 to 14 which further comprises a compliance r having a pressure sensor, wherein, when the compliance monitor is mounted onto the inhaler, the pressure sensor is in fluid communication with the orifice.
16. An inhaler according to claim 15 wherein the inhaler and / or the compliance monitor have one or more formations for detachably mounting the compliance monitor onto the r.
17. An inhaler according to claim 15 or claim 16 wherein the compliance monitor has a sealing member which surrounds the pressure sensor and forms a seal with the housing around the orifice when the compliance monitor is mounted onto the inhaler. AH26(43577055_1):BJM Vectura Delivery Devices Limited By the Attorneys for the Applicant SPRUSON & ON AH26(43577055_1):BJM
NZ786935A 2020-11-17 Inhaler for use with a compliance monitor NZ786935B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP19209858 2019-11-18
EP19209857 2019-11-18
EP19209856 2019-11-18
PCT/EP2020/082422 WO2021099324A1 (en) 2019-11-18 2020-11-17 Inhaler for use with a compliance monitor

Publications (2)

Publication Number Publication Date
NZ786935A NZ786935A (en) 2024-02-23
NZ786935B2 true NZ786935B2 (en) 2024-05-24

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