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NZ507185A - Iontophoresis, electroporation and combination catheters for local drug delivery to arteries and other body tissues - Google Patents

Iontophoresis, electroporation and combination catheters for local drug delivery to arteries and other body tissues

Info

Publication number
NZ507185A
NZ507185A NZ507185A NZ50718599A NZ507185A NZ 507185 A NZ507185 A NZ 507185A NZ 507185 A NZ507185 A NZ 507185A NZ 50718599 A NZ50718599 A NZ 50718599A NZ 507185 A NZ507185 A NZ 507185A
Authority
NZ
New Zealand
Prior art keywords
iontophoresis
electroporation
arteries
body tissues
drug delivery
Prior art date
Application number
NZ507185A
Inventor
Charles L Brown
Steven Freear
Neville Crawford
Original Assignee
Gmp Drug Delivery Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/253,272 external-priority patent/US6219577B1/en
Application filed by Gmp Drug Delivery Inc filed Critical Gmp Drug Delivery Inc
Publication of NZ507185A publication Critical patent/NZ507185A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A61N1/306—Arrangements where at least part of the apparatus is introduced into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Electrotherapy Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

This invention is a catheter-based device for enhancing the local delivery of drugs, pharmaceuticals, plasmids, genes, and other agents into the wall tissues of tubular compartments of the living body. One catheter device (16) provides an electrical driving force that can increase the rate of migration of drugs, other therapeutic agents out of a polymer matrix into body tissues, and cells using iontophoresis only. Another device (16) uses iontophoresis only, electroporation only, or combined iontophoresis and electroporation. In the latter device (16), the two procedures may be applied sequentially in any order without removing or repositioning the catheter.
NZ507185A 1998-04-14 1999-04-08 Iontophoresis, electroporation and combination catheters for local drug delivery to arteries and other body tissues NZ507185A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US8168298P 1998-04-14 1998-04-14
US8889898P 1998-06-11 1998-06-11
US09/253,272 US6219577B1 (en) 1998-04-14 1999-02-19 Iontophoresis, electroporation and combination catheters for local drug delivery to arteries and other body tissues
PCT/US1999/007703 WO1999052424A1 (en) 1998-04-14 1999-04-08 Iontophoresis, electroporation and combination catheters for local drug delivery to arteries and other body tissues

Publications (1)

Publication Number Publication Date
NZ507185A true NZ507185A (en) 2002-09-27

Family

ID=27374048

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ507185A NZ507185A (en) 1998-04-14 1999-04-08 Iontophoresis, electroporation and combination catheters for local drug delivery to arteries and other body tissues

Country Status (6)

Country Link
EP (1) EP1071365A1 (en)
JP (1) JP2003511098A (en)
AU (1) AU742057B2 (en)
CA (1) CA2326786A1 (en)
NZ (1) NZ507185A (en)
WO (1) WO1999052424A1 (en)

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CA2337652C (en) 1998-07-13 2013-03-26 Genetronics, Inc. Skin and muscle-targeted gene therapy by pulsed electrical field
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US9636174B2 (en) 2002-04-08 2017-05-02 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
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US8347891B2 (en) 2002-04-08 2013-01-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen
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US7620451B2 (en) 2005-12-29 2009-11-17 Ardian, Inc. Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach
US7756583B2 (en) 2002-04-08 2010-07-13 Ardian, Inc. Methods and apparatus for intravascularly-induced neuromodulation
US7162303B2 (en) 2002-04-08 2007-01-09 Ardian, Inc. Renal nerve stimulation method and apparatus for treatment of patients
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US7617005B2 (en) 2002-04-08 2009-11-10 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US8774922B2 (en) 2002-04-08 2014-07-08 Medtronic Ardian Luxembourg S.A.R.L. Catheter apparatuses having expandable balloons for renal neuromodulation and associated systems and methods
US7853333B2 (en) 2002-04-08 2010-12-14 Ardian, Inc. Methods and apparatus for multi-vessel renal neuromodulation
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US8512255B2 (en) 2008-01-17 2013-08-20 Christoph Scharf Device and method for the geometric determination of electrical dipole densities on the cardiac wall
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EP2259841A1 (en) 2008-02-25 2010-12-15 The University of North Carolina At Chapel Hill Delivery apparatus and associated method
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US8652129B2 (en) 2008-12-31 2014-02-18 Medtronic Ardian Luxembourg S.A.R.L. Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation
CN102421479A (en) 2009-02-26 2012-04-18 北卡罗来纳大学查珀尔希尔分校 Interventional drug delivery system and associated methods
US20110245756A1 (en) * 2009-12-03 2011-10-06 Rishi Arora Devices for material delivery, electroporation, sonoporation, and/or monitoring electrophysiological activity
JP6046041B2 (en) 2010-10-25 2016-12-14 メドトロニック アーディアン ルクセンブルク ソシエテ ア レスポンサビリテ リミテ Devices, systems, and methods for neuromodulation therapy evaluation and feedback
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US9579149B2 (en) 2014-03-13 2017-02-28 Medtronic Ardian Luxembourg S.A.R.L. Low profile catheter assemblies and associated systems and methods
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Also Published As

Publication number Publication date
AU742057B2 (en) 2001-12-13
CA2326786A1 (en) 1999-10-21
EP1071365A1 (en) 2001-01-31
AU3481499A (en) 1999-11-01
JP2003511098A (en) 2003-03-25
WO1999052424A1 (en) 1999-10-21

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