NZ296283A - Bioprosthetic tissue resistant to calcification by treatment with epoxide crosslinking agents - Google Patents
Bioprosthetic tissue resistant to calcification by treatment with epoxide crosslinking agentsInfo
- Publication number
- NZ296283A NZ296283A NZ296283A NZ29628395A NZ296283A NZ 296283 A NZ296283 A NZ 296283A NZ 296283 A NZ296283 A NZ 296283A NZ 29628395 A NZ29628395 A NZ 29628395A NZ 296283 A NZ296283 A NZ 296283A
- Authority
- NZ
- New Zealand
- Prior art keywords
- crosslinking agents
- epoxide crosslinking
- calcification
- treatment
- crosslinked
- Prior art date
Links
- 150000002118 epoxides Chemical class 0.000 title abstract 4
- 239000003431 cross linking reagent Substances 0.000 title abstract 3
- 230000002308 calcification Effects 0.000 title 1
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 239000007983 Tris buffer Substances 0.000 abstract 1
- 150000001412 amines Chemical group 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 229920000647 polyepoxide Polymers 0.000 abstract 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/02—Treatment of implants to prevent calcification or mineralisation in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
- Y10S623/92—Method or apparatus for preparing or treating prosthetic
- Y10S623/921—Blood vessel
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Botany (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicinal Preparation (AREA)
- Prostheses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32735994A | 1994-10-21 | 1994-10-21 | |
| PCT/US1995/013443 WO1996013227A1 (en) | 1994-10-21 | 1995-10-20 | Calcification-resistant bioprosthetic tissue and methods of making same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ296283A true NZ296283A (en) | 1999-11-29 |
Family
ID=23276227
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ296283A NZ296283A (en) | 1994-10-21 | 1995-10-20 | Bioprosthetic tissue resistant to calcification by treatment with epoxide crosslinking agents |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5674298A (xx) |
| EP (1) | EP0786970B1 (xx) |
| JP (1) | JPH10507673A (xx) |
| CN (1) | CN1200655C (xx) |
| AT (1) | ATE311832T1 (xx) |
| AU (1) | AU713605B2 (xx) |
| BR (1) | BR9509473A (xx) |
| CA (1) | CA2202247A1 (xx) |
| DE (1) | DE69534671T2 (xx) |
| IL (1) | IL115708A (xx) |
| NO (1) | NO971744D0 (xx) |
| NZ (1) | NZ296283A (xx) |
| WO (1) | WO1996013227A1 (xx) |
| ZA (1) | ZA958900B (xx) |
Families Citing this family (88)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE40570E1 (en) | 1994-07-29 | 2008-11-11 | Edwards Lifesciences Corporation | Apparatuses and methods for treating biological tissue to mitigate calcification |
| DE69523074T2 (de) * | 1994-07-29 | 2002-06-06 | Edwards Lifesciences Corp., Irvine | Verfahren zur behandlung von implantierbaren biologischen geweben zur verringerung von verkalkung |
| US5931969A (en) | 1994-07-29 | 1999-08-03 | Baxter International Inc. | Methods and apparatuses for treating biological tissue to mitigate calcification |
| US6254627B1 (en) | 1997-09-23 | 2001-07-03 | Diseno Y Desarrollo Medico S.A. De C.V. | Non-thrombogenic stent jacket |
| US6468300B1 (en) * | 1997-09-23 | 2002-10-22 | Diseno Y Desarrollo Medico, S.A. De C.V. | Stent covered heterologous tissue |
| US6008292A (en) * | 1997-12-02 | 1999-12-28 | Baxter International Inc. | Method for inhibiting calcification of aldehyde-fixed bioprosthetic materials |
| US6254564B1 (en) | 1998-09-10 | 2001-07-03 | Percardia, Inc. | Left ventricular conduit with blood vessel graft |
| US6214054B1 (en) | 1998-09-21 | 2001-04-10 | Edwards Lifesciences Corporation | Method for fixation of biological tissues having mitigated propensity for post-implantation calcification and thrombosis and bioprosthetic devices prepared thereby |
| JP4663120B2 (ja) | 1998-09-30 | 2011-03-30 | メドトロニック,インコーポレイテッド | 移植で使用される組織の無機質化を減少させる方法 |
| US6106555A (en) * | 1998-12-15 | 2000-08-22 | Av Healing Llc | Method for tissue fixation |
| AU5639700A (en) * | 1999-07-01 | 2001-01-22 | Biomedical Design, Inc. | Targeted anticalcification treatment |
| US7175644B2 (en) | 2001-02-14 | 2007-02-13 | Broncus Technologies, Inc. | Devices and methods for maintaining collateral channels in tissue |
| US7815590B2 (en) | 1999-08-05 | 2010-10-19 | Broncus Technologies, Inc. | Devices for maintaining patency of surgically created channels in tissue |
| US7462162B2 (en) | 2001-09-04 | 2008-12-09 | Broncus Technologies, Inc. | Antiproliferative devices for maintaining patency of surgically created channels in a body organ |
| EP1400204A1 (en) * | 1999-08-05 | 2004-03-24 | Broncus Technologies, Inc. | Methods and devices for creating collateral channels in the lungs |
| US7422563B2 (en) | 1999-08-05 | 2008-09-09 | Broncus Technologies, Inc. | Multifunctional tip catheter for applying energy to tissue and detecting the presence of blood flow |
| US6749606B2 (en) | 1999-08-05 | 2004-06-15 | Thomas Keast | Devices for creating collateral channels |
| US6712812B2 (en) | 1999-08-05 | 2004-03-30 | Broncus Technologies, Inc. | Devices for creating collateral channels |
| US7022088B2 (en) | 1999-08-05 | 2006-04-04 | Broncus Technologies, Inc. | Devices for applying energy to tissue |
| US6471723B1 (en) | 2000-01-10 | 2002-10-29 | St. Jude Medical, Inc. | Biocompatible prosthetic tissue |
| DE10010073B4 (de) | 2000-02-28 | 2005-12-22 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verankerung für implantierbare Herzklappenprothesen |
| DE10010074B4 (de) | 2000-02-28 | 2005-04-14 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Vorrichtung zur Befestigung und Verankerung von Herzklappenprothesen |
| US20020177223A1 (en) * | 2001-03-12 | 2002-11-28 | Ogle Mathew F. | Methods and compositions for crosslinking tissue |
| US7078163B2 (en) * | 2001-03-30 | 2006-07-18 | Medtronic, Inc. | Process for reducing mineralization of tissue used in transplantation |
| US8877233B2 (en) * | 2001-06-29 | 2014-11-04 | Cook Biotech Incorporated | Porous sponge matrix medical devices and methods |
| FR2828263B1 (fr) | 2001-08-03 | 2007-05-11 | Philipp Bonhoeffer | Dispositif d'implantation d'un implant et procede d'implantation du dispositif |
| US7708712B2 (en) * | 2001-09-04 | 2010-05-04 | Broncus Technologies, Inc. | Methods and devices for maintaining patency of surgically created channels in a body organ |
| US20050060041A1 (en) * | 2001-09-04 | 2005-03-17 | Broncus Technologies, Inc. | Methods and devices for maintaining surgically created channels in a body organ |
| US6878168B2 (en) | 2002-01-03 | 2005-04-12 | Edwards Lifesciences Corporation | Treatment of bioprosthetic tissues to mitigate post implantation calcification |
| ATE424830T1 (de) * | 2002-01-07 | 2009-03-15 | Philadelphia Children Hospital | Entgegenwirken bioprothetischer kalzifizierung |
| US8002740B2 (en) | 2003-07-18 | 2011-08-23 | Broncus Technologies, Inc. | Devices for maintaining patency of surgically created channels in tissue |
| US8308682B2 (en) | 2003-07-18 | 2012-11-13 | Broncus Medical Inc. | Devices for maintaining patency of surgically created channels in tissue |
| US7955788B2 (en) * | 2003-10-30 | 2011-06-07 | Medtronic, Inc. | Bioprosthetic tissue preparation with synthetic hydrogels |
| US7258434B2 (en) * | 2003-11-24 | 2007-08-21 | Lexmark International, Inc. | Inkjet printheads having multiple label placement positions for air diffusion vents |
| US20050266390A1 (en) * | 2004-06-01 | 2005-12-01 | Yuichiro Ueda | Processes for removing cells and cell debris from tissue and tissue constructs used in transplantation and tissue reconstruction |
| US8409167B2 (en) | 2004-07-19 | 2013-04-02 | Broncus Medical Inc | Devices for delivering substances through an extra-anatomic opening created in an airway |
| DE102005003632A1 (de) | 2005-01-20 | 2006-08-17 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Katheter für die transvaskuläre Implantation von Herzklappenprothesen |
| US7579381B2 (en) | 2005-03-25 | 2009-08-25 | Edwards Lifesciences Corporation | Treatment of bioprosthetic tissues to mitigate post implantation calcification |
| DE102005051849B4 (de) | 2005-10-28 | 2010-01-21 | JenaValve Technology Inc., Wilmington | Vorrichtung zur Implantation und Befestigung von Herzklappenprothesen |
| DE102005052628B4 (de) | 2005-11-04 | 2014-06-05 | Jenavalve Technology Inc. | Selbstexpandierendes, flexibles Drahtgeflecht mit integrierter Klappenprothese für den transvaskulären Herzklappenersatz und ein System mit einer solchen Vorrichtung und einem Einführkatheter |
| US20070213813A1 (en) | 2005-12-22 | 2007-09-13 | Symetis Sa | Stent-valves for valve replacement and associated methods and systems for surgery |
| CA2666485C (en) | 2006-10-27 | 2015-10-06 | Edwards Lifesciences Corporation | Biological tissue for surgical implantation |
| US9295551B2 (en) | 2007-04-13 | 2016-03-29 | Jenavalve Technology Gmbh | Methods of implanting an endoprosthesis |
| US7896915B2 (en) | 2007-04-13 | 2011-03-01 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
| US9138315B2 (en) | 2007-04-13 | 2015-09-22 | Jenavalve Technology Gmbh | Medical device for treating a heart valve insufficiency or stenosis |
| US9101691B2 (en) | 2007-06-11 | 2015-08-11 | Edwards Lifesciences Corporation | Methods for pre-stressing and capping bioprosthetic tissue |
| US8357387B2 (en) | 2007-12-21 | 2013-01-22 | Edwards Lifesciences Corporation | Capping bioprosthetic tissue to reduce calcification |
| US9044318B2 (en) | 2008-02-26 | 2015-06-02 | Jenavalve Technology Gmbh | Stent for the positioning and anchoring of a valvular prosthesis |
| WO2011104269A1 (en) | 2008-02-26 | 2011-09-01 | Jenavalve Technology Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
| US8465540B2 (en) | 2008-02-26 | 2013-06-18 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis |
| US8398704B2 (en) | 2008-02-26 | 2013-03-19 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
| US8317858B2 (en) | 2008-02-26 | 2012-11-27 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
| US9168130B2 (en) | 2008-02-26 | 2015-10-27 | Jenavalve Technology Gmbh | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
| US20100119605A1 (en) * | 2008-11-12 | 2010-05-13 | Isenburg Jason C | Compositions for tissue stabilization |
| US20100292779A1 (en) | 2009-05-15 | 2010-11-18 | Helmut Straubinger | Device for compressing a stent and a system as well as a method for loading a stent into a medical delivery system |
| EP2485687A1 (en) * | 2009-10-09 | 2012-08-15 | Vatrix Medical, Inc. | In vivo chemical stabilization of vulnerable plaque |
| US9211361B2 (en) * | 2010-03-15 | 2015-12-15 | Kemal Schankereli | Thin collagen tissue for medical device applications |
| NZ602707A (en) | 2010-03-23 | 2014-05-30 | Edwards Lifesciences Corp | Methods of conditioning sheet bioprosthetic tissue |
| US10856978B2 (en) | 2010-05-20 | 2020-12-08 | Jenavalve Technology, Inc. | Catheter system |
| US11278406B2 (en) | 2010-05-20 | 2022-03-22 | Jenavalve Technology, Inc. | Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect |
| WO2011147849A1 (en) | 2010-05-25 | 2011-12-01 | Jenavalve Technology Inc. | Prosthetic heart valve and transcatheter delivered endoprosthesis comprising a prosthetic heart valve and a stent |
| US8906601B2 (en) | 2010-06-17 | 2014-12-09 | Edwardss Lifesciences Corporation | Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates |
| WO2011160085A2 (en) | 2010-06-17 | 2011-12-22 | Edwards Lifesciences Corporation | Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates |
| US9351829B2 (en) | 2010-11-17 | 2016-05-31 | Edwards Lifesciences Corporation | Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability |
| CN102172338B (zh) * | 2011-02-28 | 2013-03-20 | 上海微创医疗器械(集团)有限公司 | 梯度浸没式化学改性人工生物瓣的装置 |
| US9486229B2 (en) | 2011-05-13 | 2016-11-08 | Broncus Medical Inc. | Methods and devices for excision of tissue |
| US8709034B2 (en) | 2011-05-13 | 2014-04-29 | Broncus Medical Inc. | Methods and devices for diagnosing, monitoring, or treating medical conditions through an opening through an airway wall |
| US9358107B2 (en) | 2011-06-30 | 2016-06-07 | Edwards Lifesciences Corporation | Systems, dies, and methods for processing pericardial tissue |
| US9510947B2 (en) | 2011-10-21 | 2016-12-06 | Jenavalve Technology, Inc. | Catheter system for introducing an expandable heart valve stent into the body of a patient |
| WO2013078235A1 (en) | 2011-11-23 | 2013-05-30 | Broncus Medical Inc | Methods and devices for diagnosing, monitoring, or treating medical conditions through an opening through an airway wall |
| DE202013011734U1 (de) | 2012-05-16 | 2014-04-29 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Katheter-Zuführsystem zum Einführen einer expandierbaren Herzklappenprothese sowie medizinische Vorrichtung zum Behandeln eines Herzklappendefekts |
| CN102727935B (zh) * | 2012-07-19 | 2014-04-23 | 陕西佰傲再生医学有限公司 | 硬脑/脊膜移植替代物的制备方法及其装置 |
| CN102793593B (zh) * | 2012-09-03 | 2015-06-10 | 于好勇 | 用于后巩膜加固术的异种巩膜片及其制备方法 |
| US10238771B2 (en) | 2012-11-08 | 2019-03-26 | Edwards Lifesciences Corporation | Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system |
| EP4098226A1 (en) | 2013-08-30 | 2022-12-07 | JenaValve Technology, Inc. | Endoprosthesis comprising a radially collapsible frame and a prosthetic valve |
| US9615922B2 (en) | 2013-09-30 | 2017-04-11 | Edwards Lifesciences Corporation | Method and apparatus for preparing a contoured biological tissue |
| US10959839B2 (en) | 2013-10-08 | 2021-03-30 | Edwards Lifesciences Corporation | Method for directing cellular migration patterns on a biological tissue |
| CN104130437B (zh) * | 2014-07-31 | 2017-05-31 | 苏州正海生物技术有限公司 | 一种硬脑/脊膜生物补片材料及其制备方法和应用 |
| EP3270825B1 (en) | 2015-03-20 | 2020-04-22 | JenaValve Technology, Inc. | Heart valve prosthesis delivery system |
| WO2016177562A1 (en) | 2015-05-01 | 2016-11-10 | Jenavalve Technology, Inc. | Device and method with reduced pacemaker rate in heart valve replacement |
| CN104990882B (zh) * | 2015-07-22 | 2018-05-01 | 杭州启明医疗器械有限公司 | 体外生物瓣钙化评价的方法及抗钙化因子溶液 |
| EP4183371A1 (en) | 2016-05-13 | 2023-05-24 | JenaValve Technology, Inc. | Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath and loading system |
| JP7094965B2 (ja) | 2017-01-27 | 2022-07-04 | イエナバルブ テクノロジー インク | 心臓弁模倣 |
| CN110678590B (zh) | 2017-05-31 | 2022-07-19 | 爱德华兹生命科学公司 | 胶原纤维和由其形成的制品 |
| CA3081049A1 (en) | 2018-01-23 | 2019-08-01 | Edwards Lifesciences Corporation | Method for pre-stretching implantable biocompatible materials, and materials and devices produced thereby |
| CA3116158A1 (en) | 2018-11-01 | 2020-05-07 | Edwards Lifesciences Corporation | Transcatheter pulmonic regenerative valve |
| RU2741224C1 (ru) * | 2019-12-18 | 2021-01-22 | Общество с ограниченной ответственностью "Ангиолайн Ресерч" | Способ обработки биологической ткани для имплантируемого биопротеза |
| WO2024102411A1 (en) | 2022-11-09 | 2024-05-16 | Jenavalve Technology, Inc. | Catheter system for sequential deployment of an expandable implant |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4282322A (en) * | 1975-11-24 | 1981-08-04 | Merck & Co., Inc. | Process for enzymatic deacylation of antibiotics |
| US4283494A (en) * | 1978-04-26 | 1981-08-11 | Meito Sangyo Kabushiki Kaisha | Microbial lipase, process for its preparation and microbiologically pure culture therefor |
| US4446122A (en) * | 1979-12-28 | 1984-05-01 | Research Corporation | Purified human prostate antigen |
| US4885005A (en) * | 1982-11-12 | 1989-12-05 | Baxter International Inc. | Surfactant treatment of implantable biological tissue to inhibit calcification |
| JPH0611305B2 (ja) * | 1985-07-29 | 1994-02-16 | 株式会社高研 | 抗血栓性材料の製造方法 |
| JP2529112B2 (ja) * | 1987-08-31 | 1996-08-28 | 株式会社 高研 | 生体弁 |
| US4976733A (en) * | 1988-02-03 | 1990-12-11 | Biomedical Design, Inc. | Prevention of prosthesis calcification |
| WO1992009309A2 (en) * | 1990-11-28 | 1992-06-11 | Baxter International Inc. | Method of liquid sterilization |
| US5314874A (en) * | 1991-04-19 | 1994-05-24 | Koken Co., Ltd. | Intracorporeally injectable composition for implanting highly concentrated cross-linked atelocollagen |
| US5436291A (en) * | 1992-07-09 | 1995-07-25 | University Of Michigan, The Board Of . . . | Calcification-resistant synthetic biomaterials |
| US5296583A (en) * | 1992-07-09 | 1994-03-22 | University Of Michigan | Calcification-resistant synthetic biomaterials |
| WO1994017841A1 (en) * | 1993-02-01 | 1994-08-18 | Baxter International Inc. | Biological grafts having regionalized differences in cross-link density and their methods of manufacture |
-
1995
- 1995-06-07 US US08/478,287 patent/US5674298A/en not_active Expired - Lifetime
- 1995-10-20 NZ NZ296283A patent/NZ296283A/xx unknown
- 1995-10-20 CN CNB951955640A patent/CN1200655C/zh not_active Expired - Fee Related
- 1995-10-20 JP JP8514645A patent/JPH10507673A/ja not_active Ceased
- 1995-10-20 CA CA002202247A patent/CA2202247A1/en not_active Abandoned
- 1995-10-20 BR BR9509473A patent/BR9509473A/pt not_active Application Discontinuation
- 1995-10-20 DE DE69534671T patent/DE69534671T2/de not_active Expired - Fee Related
- 1995-10-20 AT AT95938792T patent/ATE311832T1/de not_active IP Right Cessation
- 1995-10-20 EP EP95938792A patent/EP0786970B1/en not_active Expired - Lifetime
- 1995-10-20 IL IL11570895A patent/IL115708A/xx not_active IP Right Cessation
- 1995-10-20 ZA ZA958900A patent/ZA958900B/xx unknown
- 1995-10-20 AU AU40037/95A patent/AU713605B2/en not_active Ceased
- 1995-10-20 WO PCT/US1995/013443 patent/WO1996013227A1/en not_active Ceased
-
1997
- 1997-04-16 NO NO971744A patent/NO971744D0/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU713605B2 (en) | 1999-12-09 |
| AU4003795A (en) | 1996-05-23 |
| NO971744L (no) | 1997-04-16 |
| EP0786970A1 (en) | 1997-08-06 |
| EP0786970A4 (en) | 2000-04-05 |
| DE69534671D1 (de) | 2006-01-12 |
| CN1162252A (zh) | 1997-10-15 |
| DE69534671T2 (de) | 2006-07-13 |
| US5674298A (en) | 1997-10-07 |
| NO971744D0 (no) | 1997-04-16 |
| IL115708A (en) | 2000-11-21 |
| CN1200655C (zh) | 2005-05-11 |
| EP0786970B1 (en) | 2005-12-07 |
| BR9509473A (pt) | 1997-09-30 |
| JPH10507673A (ja) | 1998-07-28 |
| IL115708A0 (en) | 1996-08-04 |
| CA2202247A1 (en) | 1996-05-09 |
| ZA958900B (en) | 1997-04-15 |
| WO1996013227A1 (en) | 1996-05-09 |
| ATE311832T1 (de) | 2005-12-15 |
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