NZ257765A - Antibacterial mouthwash/oral hygiene composition - Google Patents
Antibacterial mouthwash/oral hygiene compositionInfo
- Publication number
- NZ257765A NZ257765A NZ257765A NZ25776593A NZ257765A NZ 257765 A NZ257765 A NZ 257765A NZ 257765 A NZ257765 A NZ 257765A NZ 25776593 A NZ25776593 A NZ 25776593A NZ 257765 A NZ257765 A NZ 257765A
- Authority
- NZ
- New Zealand
- Prior art keywords
- weight
- hygiene composition
- oral
- composition according
- oral hygiene
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 81
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 20
- 239000002324 mouth wash Substances 0.000 title claims description 17
- 229940051866 mouthwash Drugs 0.000 title description 7
- 239000000796 flavoring agent Substances 0.000 claims abstract description 18
- 235000013355 food flavoring agent Nutrition 0.000 claims abstract description 13
- 239000006172 buffering agent Substances 0.000 claims abstract description 12
- 239000004094 surface-active agent Substances 0.000 claims abstract description 10
- 235000003599 food sweetener Nutrition 0.000 claims abstract description 9
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 claims abstract description 9
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 claims abstract description 9
- 239000004299 sodium benzoate Substances 0.000 claims abstract description 9
- 235000010234 sodium benzoate Nutrition 0.000 claims abstract description 9
- 239000003765 sweetening agent Substances 0.000 claims abstract description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 8
- 230000000694 effects Effects 0.000 claims abstract description 6
- 210000000214 mouth Anatomy 0.000 claims description 22
- 244000005700 microbiome Species 0.000 claims description 20
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 11
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 10
- 230000002401 inhibitory effect Effects 0.000 claims description 9
- 239000002253 acid Substances 0.000 claims description 8
- 230000005764 inhibitory process Effects 0.000 claims description 6
- 239000008368 mint flavor Substances 0.000 claims description 6
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims description 5
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims description 5
- 235000019634 flavors Nutrition 0.000 claims description 5
- 239000001509 sodium citrate Substances 0.000 claims description 5
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical group O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 5
- 101100114828 Drosophila melanogaster Orai gene Proteins 0.000 claims description 4
- 244000246386 Mentha pulegium Species 0.000 claims description 4
- 235000016257 Mentha pulegium Nutrition 0.000 claims description 4
- 235000004357 Mentha x piperita Nutrition 0.000 claims description 4
- 150000008051 alkyl sulfates Chemical class 0.000 claims description 4
- 235000001050 hortel pimenta Nutrition 0.000 claims description 4
- 229910052708 sodium Inorganic materials 0.000 claims description 4
- 239000011734 sodium Substances 0.000 claims description 4
- 241000894006 Bacteria Species 0.000 claims description 3
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical group [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims description 3
- 239000003945 anionic surfactant Substances 0.000 claims description 3
- 239000003242 anti bacterial agent Substances 0.000 claims description 3
- 238000012986 modification Methods 0.000 claims description 3
- 230000004048 modification Effects 0.000 claims description 3
- MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 claims description 3
- 239000005711 Benzoic acid Substances 0.000 claims description 2
- 241000222122 Candida albicans Species 0.000 claims description 2
- 150000003863 ammonium salts Chemical class 0.000 claims description 2
- 235000010233 benzoic acid Nutrition 0.000 claims description 2
- QEEAPRPFLLJWCF-UHFFFAOYSA-K potassium citrate (anhydrous) Chemical compound [K+].[K+].[K+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O QEEAPRPFLLJWCF-UHFFFAOYSA-K 0.000 claims description 2
- 229940085606 rembrandt Drugs 0.000 claims description 2
- 150000003839 salts Chemical class 0.000 claims description 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims 3
- 235000014749 Mentha crispa Nutrition 0.000 claims 3
- 244000078639 Mentha spicata Species 0.000 claims 3
- 239000000341 volatile oil Substances 0.000 claims 3
- 230000001476 alcoholic effect Effects 0.000 claims 2
- 235000019333 sodium laurylsulphate Nutrition 0.000 claims 2
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims 1
- 235000011054 acetic acid Nutrition 0.000 claims 1
- 239000003513 alkali Substances 0.000 claims 1
- 229940076522 listerine Drugs 0.000 claims 1
- 229910052751 metal Inorganic materials 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 239000011975 tartaric acid Substances 0.000 claims 1
- 235000002906 tartaric acid Nutrition 0.000 claims 1
- 230000003139 buffering effect Effects 0.000 abstract description 2
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 208000002925 dental caries Diseases 0.000 description 6
- -1 hydrogen ions Chemical class 0.000 description 6
- 239000004615 ingredient Substances 0.000 description 6
- 235000013305 food Nutrition 0.000 description 5
- 238000009472 formulation Methods 0.000 description 5
- 241001148536 Bacteroides sp. Species 0.000 description 4
- 229920001817 Agar Polymers 0.000 description 3
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 3
- 239000008272 agar Substances 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 210000003298 dental enamel Anatomy 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 3
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical group N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 2
- 208000024693 gingival disease Diseases 0.000 description 2
- 208000007565 gingivitis Diseases 0.000 description 2
- 239000008103 glucose Substances 0.000 description 2
- 238000010348 incorporation Methods 0.000 description 2
- 238000001802 infusion Methods 0.000 description 2
- 150000002500 ions Chemical class 0.000 description 2
- 239000001683 mentha spicata herb oil Substances 0.000 description 2
- OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 description 2
- 239000003755 preservative agent Substances 0.000 description 2
- 230000002035 prolonged effect Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 235000019721 spearmint oil Nutrition 0.000 description 2
- KFZXVMNBUMVKLN-UHFFFAOYSA-N 4-chloro-5-methyl-2-propan-2-ylphenol Chemical compound CC(C)C1=CC(Cl)=C(C)C=C1O KFZXVMNBUMVKLN-UHFFFAOYSA-N 0.000 description 1
- 241000234282 Allium Species 0.000 description 1
- 235000002732 Allium cepa var. cepa Nutrition 0.000 description 1
- 240000002234 Allium sativum Species 0.000 description 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 1
- 108010039862 Biotene Proteins 0.000 description 1
- 241000754798 Calophyllum brasiliense Species 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 244000037364 Cinnamomum aromaticum Species 0.000 description 1
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 description 1
- 244000223760 Cinnamomum zeylanicum Species 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- 208000002064 Dental Plaque Diseases 0.000 description 1
- 241001573476 Filodes Species 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 241000186660 Lactobacillus Species 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 235000007265 Myrrhis odorata Nutrition 0.000 description 1
- 229930182555 Penicillin Natural products 0.000 description 1
- 240000004760 Pimpinella anisum Species 0.000 description 1
- 235000012550 Pimpinella anisum Nutrition 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 102000001848 Salivary Proteins and Peptides Human genes 0.000 description 1
- 108010029987 Salivary Proteins and Peptides Proteins 0.000 description 1
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 241000194019 Streptococcus mutans Species 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 239000005844 Thymol Substances 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 229910052783 alkali metal Inorganic materials 0.000 description 1
- 150000001340 alkali metals Chemical class 0.000 description 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 239000008122 artificial sweetener Substances 0.000 description 1
- 235000021311 artificial sweeteners Nutrition 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- XKXHCNPAFAXVRZ-UHFFFAOYSA-N benzylazanium;chloride Chemical compound [Cl-].[NH3+]CC1=CC=CC=C1 XKXHCNPAFAXVRZ-UHFFFAOYSA-N 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 229940095731 candida albicans Drugs 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229940031956 chlorothymol Drugs 0.000 description 1
- 235000017803 cinnamon Nutrition 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000013020 final formulation Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 235000004611 garlic Nutrition 0.000 description 1
- ACGUYXCXAPNIKK-UHFFFAOYSA-N hexachlorophene Chemical compound OC1=C(Cl)C=C(Cl)C(Cl)=C1CC1=C(O)C(Cl)=CC(Cl)=C1Cl ACGUYXCXAPNIKK-UHFFFAOYSA-N 0.000 description 1
- 229960004068 hexachlorophene Drugs 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
- 229940039696 lactobacillus Drugs 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000001525 mentha piperita l. herb oil Substances 0.000 description 1
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 description 1
- 229960001047 methyl salicylate Drugs 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 239000003607 modifier Substances 0.000 description 1
- 235000021096 natural sweeteners Nutrition 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 229940049954 penicillin Drugs 0.000 description 1
- 235000019477 peppermint oil Nutrition 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229960003975 potassium Drugs 0.000 description 1
- VKJKEPKFPUWCAS-UHFFFAOYSA-M potassium chlorate Chemical compound [K+].[O-]Cl(=O)=O VKJKEPKFPUWCAS-UHFFFAOYSA-M 0.000 description 1
- 239000001508 potassium citrate Substances 0.000 description 1
- 229960002635 potassium citrate Drugs 0.000 description 1
- 235000011082 potassium citrates Nutrition 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 150000003856 quaternary ammonium compounds Chemical class 0.000 description 1
- 239000001632 sodium acetate Substances 0.000 description 1
- 235000017281 sodium acetate Nutrition 0.000 description 1
- 235000011083 sodium citrates Nutrition 0.000 description 1
- 229960001922 sodium perborate Drugs 0.000 description 1
- 229960000776 sodium tetradecyl sulfate Drugs 0.000 description 1
- YKLJGMBLPUQQOI-UHFFFAOYSA-M sodium;oxidooxy(oxo)borane Chemical compound [Na+].[O-]OB=O YKLJGMBLPUQQOI-UHFFFAOYSA-M 0.000 description 1
- UPUIQOIQVMNQAP-UHFFFAOYSA-M sodium;tetradecyl sulfate Chemical compound [Na+].CCCCCCCCCCCCCCOS([O-])(=O)=O UPUIQOIQVMNQAP-UHFFFAOYSA-M 0.000 description 1
- 230000007928 solubilization Effects 0.000 description 1
- 238000005063 solubilization Methods 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 229960000790 thymol Drugs 0.000 description 1
- AQLJVWUFPCUVLO-UHFFFAOYSA-N urea hydrogen peroxide Chemical compound OO.NC(N)=O AQLJVWUFPCUVLO-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96776892A | 1992-10-28 | 1992-10-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ257765A true NZ257765A (en) | 1996-09-25 |
Family
ID=25513286
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ257765A NZ257765A (en) | 1992-10-28 | 1993-10-26 | Antibacterial mouthwash/oral hygiene composition |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5707610A (fr) |
| EP (1) | EP0666731B1 (fr) |
| JP (1) | JP3756945B2 (fr) |
| KR (1) | KR100296414B1 (fr) |
| AT (1) | ATE275927T1 (fr) |
| AU (2) | AU5453894A (fr) |
| BR (1) | BR9307332A (fr) |
| CA (1) | CA2146330C (fr) |
| DE (1) | DE69333625T2 (fr) |
| DK (2) | DK0666731T3 (fr) |
| ES (1) | ES2227520T3 (fr) |
| GE (1) | GEP20002228B (fr) |
| NO (1) | NO308393B1 (fr) |
| NZ (1) | NZ257765A (fr) |
| PL (1) | PL173704B1 (fr) |
| PT (1) | PT666731E (fr) |
| RU (1) | RU2125440C1 (fr) |
| WO (1) | WO1994009752A1 (fr) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2143037C (fr) * | 1994-05-02 | 2002-04-30 | Atma Chaudhari | Rince-bouche exempt d'alcool |
| CN1083270C (zh) * | 1996-12-05 | 2002-04-24 | Lg化学株式会社 | 含有牛膝或榆白皮提取物的口腔用组合物 |
| US6638175B2 (en) * | 1999-05-12 | 2003-10-28 | Callaway Golf Company | Diagnostic golf club system |
| AU5871000A (en) * | 1999-06-11 | 2001-01-02 | Paul G. Abrams | High dose radionuclide complexes for bone marrow suppression |
| US7094885B2 (en) * | 1999-07-11 | 2006-08-22 | Neorx Corporation | Skeletal-targeted radiation to treat bone-associated pathologies |
| US6927197B1 (en) * | 1999-11-08 | 2005-08-09 | Water Journey Ltd. | Antibacterial compositions and method of using same |
| WO2002062398A2 (fr) * | 2001-01-08 | 2002-08-15 | Neorx Corporation | Composes, compositions et methodes therapeutiques et diagnostiques |
| US6610276B2 (en) * | 2001-01-12 | 2003-08-26 | Steven A. Melman | Multi-functional dental composition |
| JP2002255720A (ja) * | 2001-03-05 | 2002-09-11 | Gc Corp | 炭酸化した水酸化カルシウム系根管充填材の溶解剤 |
| RU2180835C1 (ru) * | 2001-04-28 | 2002-03-27 | Каспаров Эдуард Вильямович | Зубной эликсир |
| AU2002364552A1 (en) | 2001-12-13 | 2003-06-30 | Dow Global Technologies Inc. | Treatment of osteomyelitis with radiopharmaceuticals |
| BR0315942A (pt) | 2002-11-27 | 2005-10-04 | Dmi Biosciences Inc | Tratamento de doenças e condições mediadas pelo aumento de fosforilação |
| KR20060088543A (ko) * | 2003-09-25 | 2006-08-04 | 디엠아이 바이오사이언스 인코포레이티드 | 앤-아실-엘-아스파틱산을 이용하는 방법 및 제품 |
| US20090232748A1 (en) * | 2003-11-07 | 2009-09-17 | Viratox, L.L.C. | Virucidal activities of cetylpyridinium chloride |
| US20050170013A1 (en) * | 2004-02-04 | 2005-08-04 | Douglas Jerry A. | Composition for treating a dermatological inflammatory response and method of preparation thereof |
| RU2253435C1 (ru) * | 2004-03-09 | 2005-06-10 | Закрытое акционерное общество "Деско" (ЗАО "Деско") | Профилактическое средство для ухода за полостью рта |
| US7297327B2 (en) * | 2004-12-21 | 2007-11-20 | Colgate-Palmolive Company | Oral care malodor composition |
| JP2007153841A (ja) * | 2005-12-07 | 2007-06-21 | Wakoudou Kk | 口腔用組成物 |
| US8741954B2 (en) * | 2007-02-21 | 2014-06-03 | Viratox, L.L.C. | Synergistic enhancement of calcium propionate |
| US20120003162A1 (en) | 2010-06-30 | 2012-01-05 | Mcneil-Ppc, Inc. | Methods of Preparing Non-Alcohol Bioactive Esential Oil Mouth Rinses |
| US9084902B2 (en) | 2010-06-30 | 2015-07-21 | Mcneil-Ppc, Inc. | Non-alchohol bioactive essential oil mouth rinses |
| EA201001053A1 (ru) * | 2010-07-08 | 2011-10-31 | Общество С Ограниченной Ответственностью "Вдс" | Состав для профилактики кандидозов |
| US20130224125A1 (en) * | 2010-08-03 | 2013-08-29 | Narayanan S. Kolazi | Alcohol-free slightly-alcoholic oral care composition and a process for preparing same |
| RU2552936C2 (ru) | 2010-11-12 | 2015-06-10 | Колгейт-Палмолив Компани | Продукт для ухода за полостью рта и способы его применения и получения |
| WO2012075257A2 (fr) * | 2010-12-01 | 2012-06-07 | The University Of Georgia Research Foundation, Inc. | Compositions destinées à l'hygiène orale et nasale |
| NO339503B1 (no) * | 2014-06-18 | 2016-12-19 | Meda Otc Ab | Sammensetning for forebygging eller behandling av dental erosjon |
| RU2572705C1 (ru) * | 2014-11-25 | 2016-01-20 | Татьяна Георгиевна Неустроева | Композиция для полоскания полости рта |
| US10524993B2 (en) | 2015-11-19 | 2020-01-07 | Fantarella & Harewood, Llc | Mouthwash composition |
| WO2019015955A1 (fr) * | 2017-07-20 | 2019-01-24 | Thomas Leibbrand | Tyrothricine destinée à être utilisée lors du traitement ou de la prophylaxie de l'odeur corporelle ainsi que préparations correspondantes |
| US20230111214A1 (en) * | 2021-10-08 | 2023-04-13 | Inolex Investment Corporation | Biobased polyglyceryl esters and compositions comprising the same |
| KR102730644B1 (ko) * | 2022-07-05 | 2024-11-15 | 강원대학교산학협력단 | 미산성 차아염소산수 및 벤조산나트륨을 포함하는 구강청결제 조성물 |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE321765B (fr) * | 1968-11-29 | 1970-03-16 | K Holmstroem | |
| US3864472A (en) * | 1972-11-06 | 1975-02-04 | Colgate Palmolive Co | Clear lemon-flavored mouthwash |
| US3947570A (en) * | 1972-11-06 | 1976-03-30 | Colgate-Palmolive Company | Oral product |
| US3876759A (en) * | 1973-01-04 | 1975-04-08 | Colgate Palmolive Co | Method of making clear lemon-flavored mouthwash |
| US4011309A (en) * | 1975-01-20 | 1977-03-08 | Marion Laboratories, Inc. | Dentifrice composition and method for desensitizing sensitive teeth |
| US4150151A (en) * | 1977-12-12 | 1979-04-17 | Lever Brothers Company | Mouthwash |
| JPS5557513A (en) * | 1978-10-23 | 1980-04-28 | Richardson Merrell Inc | Oral detergent composition |
| US4465661A (en) * | 1979-11-14 | 1984-08-14 | Basf Wyandotte Corporation | Oral product having improved taste |
| EP0095871A3 (fr) * | 1982-05-27 | 1984-06-13 | Reckitt And Colman Products Limited | Compositions de traitement dentaire |
| US4476107A (en) * | 1983-06-13 | 1984-10-09 | Basf Wyandotte Corporation | Mouthwash composition |
| US4950479A (en) * | 1986-11-06 | 1990-08-21 | Hill Ira D | Method of interrupting the formation of plaque |
| US4657758A (en) * | 1984-01-27 | 1987-04-14 | Oral Research Laboratories, Inc. | Dental rinse |
| US4666708A (en) * | 1984-01-27 | 1987-05-19 | Oral Research Laboratories, Inc. | Dental rinse |
| US4610872A (en) * | 1984-12-21 | 1986-09-09 | Ici Americas Inc. | Dentifrice formulation and method of treating teeth, mouth and throat therewith to reduce plaque accumulation and irritation |
| US4585649A (en) * | 1984-12-21 | 1986-04-29 | Ici Americas Inc. | Dentifrice formulation and method of treating teeth, mouth and throat therewith to reduce plaque accumulation and irritation |
| DE3504178A1 (de) * | 1985-02-07 | 1986-08-14 | Blendax Werke Schneider Co | Zahnpasta |
| JPH01501472A (ja) * | 1986-07-11 | 1989-05-25 | オラル、リサーチ、ラボラトリーズ、インコーポレーテッド | 抗歯垢剤の作用を延長させるための組成物 |
| GB8706187D0 (en) * | 1987-03-16 | 1987-04-23 | Unilever Plc | Dentifrice compositions |
| DE3725248A1 (de) * | 1987-07-30 | 1989-02-09 | Henkel Kgaa | Antimikrobiell wirksame, aromatisierte zubereitungen |
| GB8719775D0 (en) * | 1987-08-21 | 1987-09-30 | Unilever Plc | Oral products |
| US4919918A (en) * | 1988-03-14 | 1990-04-24 | Spectrum Consumer Products Co., Inc. | Non-alcoholic mouthwash |
| JPH0651618B2 (ja) * | 1988-05-11 | 1994-07-06 | 日本歯研工業株式会社 | 歯牙口腔液体洗滌剤 |
| DE3816522A1 (de) * | 1988-05-14 | 1989-01-12 | Biodyn Ag | Schutzmittel gegen karies |
| DE3903348A1 (de) * | 1989-02-04 | 1990-08-30 | Henkel Kgaa | Mund- und zahnpflegemittel mit polysaccharidspaltenden enzymen |
| SE463189B (sv) * | 1989-03-13 | 1990-10-22 | Eston Joensson | Preparat avsett att tillfoeras amalgamfyllningar i taender foer att daerigenom hindra eller minska avgaang av kvicksilver eller kvicksilveraanga |
| US5284648A (en) * | 1989-03-17 | 1994-02-08 | White Robert D | Alcohol-free, oral rinse and pre-rinse emulsions method of prepration and method of use |
| US5089255A (en) * | 1989-06-26 | 1992-02-18 | Colgate-Palmolive Company | Dental remineralization |
| DE3927011A1 (de) * | 1989-08-16 | 1991-02-21 | Henkel Kgaa | Zahnsteinhemmende mund- und zahnpflegemittel |
| US5116602A (en) * | 1989-09-27 | 1992-05-26 | Colgate-Palmolive Company | Antiplaque oral compositions |
| US5174990A (en) * | 1990-02-07 | 1992-12-29 | 7-L Corporation | Mouthrinse and method of preparation |
| CA2019719A1 (fr) * | 1990-06-25 | 1991-12-25 | William J. Thompson | Bain de bouche |
| US5328682A (en) * | 1990-10-25 | 1994-07-12 | Boots Company Plc | Mouthwash |
| US5143720A (en) * | 1990-11-28 | 1992-09-01 | Microcide, Inc. | Disinfecting and sanitizing compositions |
| JP3446214B2 (ja) * | 1991-06-21 | 2003-09-16 | ライオン株式会社 | 液状透明口腔用組成物 |
| US5338538A (en) * | 1991-07-29 | 1994-08-16 | Pfizer Inc | Prebrushing pyrophosphate-containing liquid oral compositions |
| US5213790A (en) * | 1991-10-23 | 1993-05-25 | The Procter & Gamble Co. | Methods of reducing plaque and gingivitis with reduced staining |
| JP3362403B2 (ja) * | 1992-03-17 | 2003-01-07 | ライオン株式会社 | 義歯装着者用洗口剤 |
| US5229103A (en) * | 1992-04-30 | 1993-07-20 | Hydrodent Laboratories, Inc. | Antiplaque mouthwash concentrate |
| JPH05339135A (ja) * | 1992-06-09 | 1993-12-21 | Lion Corp | 口腔用組成物 |
| US5514366A (en) * | 1993-04-07 | 1996-05-07 | Diamond; Jeffrey H. | Dental and oral preparation for smokers for solubilizing and removing tobacco tars as well as onion and garlic essential oils |
| US5283056A (en) * | 1993-07-01 | 1994-02-01 | International Flavors & Fragrances Inc. | Transparent oil-in-water microemulsion flavor or fragrance concentrate, process for preparing same, mouthwash or perfume composition containing said transparent microemulsion concentrate, and process for preparing same |
| US5560906A (en) * | 1995-03-27 | 1996-10-01 | Oral Technology Laboratories, Inc. | Non-alcoholic antimicrobial mouthwash for removal of dental plaque |
-
1993
- 1993-10-26 EP EP93925093A patent/EP0666731B1/fr not_active Expired - Lifetime
- 1993-10-26 PL PL93308359A patent/PL173704B1/pl not_active IP Right Cessation
- 1993-10-26 AT AT93925093T patent/ATE275927T1/de not_active IP Right Cessation
- 1993-10-26 ES ES93925093T patent/ES2227520T3/es not_active Expired - Lifetime
- 1993-10-26 AU AU54538/94A patent/AU5453894A/en not_active Abandoned
- 1993-10-26 JP JP51129994A patent/JP3756945B2/ja not_active Expired - Fee Related
- 1993-10-26 GE GEAP19932580A patent/GEP20002228B/en unknown
- 1993-10-26 KR KR1019950701279A patent/KR100296414B1/ko not_active Expired - Fee Related
- 1993-10-26 DE DE69333625T patent/DE69333625T2/de not_active Expired - Fee Related
- 1993-10-26 PT PT93925093T patent/PT666731E/pt unknown
- 1993-10-26 CA CA002146330A patent/CA2146330C/fr not_active Expired - Fee Related
- 1993-10-26 NZ NZ257765A patent/NZ257765A/en not_active IP Right Cessation
- 1993-10-26 RU RU95114536A patent/RU2125440C1/ru not_active IP Right Cessation
- 1993-10-26 BR BR9307332A patent/BR9307332A/pt not_active IP Right Cessation
- 1993-10-26 WO PCT/US1993/010329 patent/WO1994009752A1/fr not_active Ceased
- 1993-10-26 DK DK93925093T patent/DK0666731T3/da active
-
1995
- 1995-03-30 NO NO951239A patent/NO308393B1/no unknown
- 1995-04-04 DK DK038095A patent/DK38095A/da not_active Application Discontinuation
- 1995-05-30 US US08/453,484 patent/US5707610A/en not_active Expired - Lifetime
-
1998
- 1998-02-23 AU AU56263/98A patent/AU702781B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| NO308393B1 (no) | 2000-09-11 |
| DE69333625T2 (de) | 2005-09-22 |
| EP0666731A1 (fr) | 1995-08-16 |
| AU5453894A (en) | 1994-05-24 |
| NO951239D0 (no) | 1995-03-30 |
| JPH08502970A (ja) | 1996-04-02 |
| NO951239L (no) | 1995-04-27 |
| PL173704B1 (pl) | 1998-04-30 |
| DK0666731T3 (da) | 2004-10-18 |
| ATE275927T1 (de) | 2004-10-15 |
| AU702781B2 (en) | 1999-03-04 |
| KR100296414B1 (ko) | 2001-10-24 |
| CA2146330C (fr) | 2000-04-25 |
| WO1994009752A1 (fr) | 1994-05-11 |
| US5707610A (en) | 1998-01-13 |
| PL308359A1 (en) | 1995-07-24 |
| DE69333625D1 (de) | 2004-10-21 |
| EP0666731A4 (fr) | 1997-03-05 |
| JP3756945B2 (ja) | 2006-03-22 |
| RU2125440C1 (ru) | 1999-01-27 |
| RU95114536A (ru) | 1997-02-27 |
| EP0666731B1 (fr) | 2004-09-15 |
| AU5626398A (en) | 1998-05-07 |
| BR9307332A (pt) | 1999-06-01 |
| DK38095A (da) | 1995-04-25 |
| ES2227520T3 (es) | 2005-04-01 |
| PT666731E (pt) | 2004-11-30 |
| KR950703322A (ko) | 1995-09-20 |
| GEP20002228B (en) | 2000-09-25 |
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Legal Events
| Date | Code | Title | Description |
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| RENW | Renewal (renewal fees accepted) | ||
| RENW | Renewal (renewal fees accepted) | ||
| EXPY | Patent expired |