NZ239909A - Anti hiv agents containing glycoprotein cd-4 and dextrin sulphate - Google Patents
Anti hiv agents containing glycoprotein cd-4 and dextrin sulphateInfo
- Publication number
- NZ239909A NZ239909A NZ239909A NZ23990991A NZ239909A NZ 239909 A NZ239909 A NZ 239909A NZ 239909 A NZ239909 A NZ 239909A NZ 23990991 A NZ23990991 A NZ 23990991A NZ 239909 A NZ239909 A NZ 239909A
- Authority
- NZ
- New Zealand
- Prior art keywords
- agent
- agents containing
- hiv agents
- anti hiv
- containing glycoprotein
- Prior art date
Links
- 239000002259 anti human immunodeficiency virus agent Substances 0.000 title abstract 3
- 229940124411 anti-hiv antiviral agent Drugs 0.000 title abstract 3
- 229920001353 Dextrin Polymers 0.000 title 1
- 239000004375 Dextrin Substances 0.000 title 1
- 102000003886 Glycoproteins Human genes 0.000 title 1
- 108090000288 Glycoproteins Proteins 0.000 title 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 title 1
- 235000019425 dextrin Nutrition 0.000 title 1
- 229910021653 sulphate ion Inorganic materials 0.000 title 1
- 239000000463 material Substances 0.000 abstract 4
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 208000031886 HIV Infections Diseases 0.000 abstract 1
- 208000037357 HIV infectious disease Diseases 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 230000000996 additive effect Effects 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
The invention provides an agent against HIV and related viruses, in dosage unit form, comprising CD4 or a CD4-like material and a polyanionic anti-HIV agent, the content of CD4 or CD4-like material in the agent being less than the anti-virally effective dose of the CD4 or CD4-like material alone. It has been found that when the CD4 or CD4-like material is used together with a polyanionic anti-HIV agent, the combination is more effective against HIV infection than would be the case if the anti-viral effect was simply additive.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909020872A GB9020872D0 (en) | 1990-09-25 | 1990-09-25 | Pharmaceutical compositions and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ239909A true NZ239909A (en) | 1993-02-25 |
Family
ID=10682731
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ239909A NZ239909A (en) | 1990-09-25 | 1991-09-23 | Anti hiv agents containing glycoprotein cd-4 and dextrin sulphate |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0550529A1 (en) |
| JP (1) | JPH06502846A (en) |
| AU (1) | AU653962B2 (en) |
| CA (1) | CA2092093A1 (en) |
| GB (1) | GB9020872D0 (en) |
| IE (1) | IE913341A1 (en) |
| NZ (1) | NZ239909A (en) |
| PT (1) | PT99058B (en) |
| WO (1) | WO1992004909A1 (en) |
| ZA (1) | ZA917596B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5272261A (en) * | 1989-01-11 | 1993-12-21 | Merrell Dow Pharmaceuticals Inc. | Preparation of sulfated polysaccharide fractions |
| GB9209874D0 (en) * | 1992-05-07 | 1992-06-24 | Ml Lab Plc | Pharmaceutical compositions |
| FR2838649B1 (en) * | 2002-04-19 | 2006-01-13 | Commissariat Energie Atomique | ANTI-HIV COMPOSITION, METHOD OF MANUFACTURE AND MEDICINAL PRODUCT |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0293826A3 (en) * | 1987-06-02 | 1989-05-10 | Stichting REGA V.Z.W. | Therapeutic and prophylactic application of sulfated polysaccharides against aids |
| DE3808353A1 (en) * | 1988-03-12 | 1989-09-21 | Basf Ag | COMBINATIONS OF POLYSULFATED HEPARINES IN THE FIGHT AGAINST RETROVIRUS INFECTIONS |
| AU3831889A (en) * | 1988-06-10 | 1990-01-05 | Biogen, Inc. | Combinations of soluble t4 proteins and anti-retroviral agents and methods for treating or preventing aids, arc and hiv infection |
| DE68924774T2 (en) * | 1988-07-07 | 1996-05-02 | Univ Pennsylvania | MODULATION OF VIRUS-HOST CELL INTERACTIONS USING CYCLIC OLIGOSACCHARIDES. |
-
1990
- 1990-09-25 GB GB909020872A patent/GB9020872D0/en active Pending
-
1991
- 1991-09-23 JP JP3515281A patent/JPH06502846A/en active Pending
- 1991-09-23 NZ NZ239909A patent/NZ239909A/en unknown
- 1991-09-23 AU AU86127/91A patent/AU653962B2/en not_active Ceased
- 1991-09-23 CA CA002092093A patent/CA2092093A1/en not_active Abandoned
- 1991-09-23 WO PCT/GB1991/001627 patent/WO1992004909A1/en not_active Ceased
- 1991-09-23 EP EP91916829A patent/EP0550529A1/en not_active Withdrawn
- 1991-09-24 ZA ZA917596A patent/ZA917596B/en unknown
- 1991-09-24 IE IE334191A patent/IE913341A1/en not_active Application Discontinuation
- 1991-09-25 PT PT99058A patent/PT99058B/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU8612791A (en) | 1992-04-15 |
| ZA917596B (en) | 1992-05-27 |
| JPH06502846A (en) | 1994-03-31 |
| PT99058A (en) | 1992-08-31 |
| AU653962B2 (en) | 1994-10-20 |
| PT99058B (en) | 1999-02-26 |
| CA2092093A1 (en) | 1992-03-26 |
| IE913341A1 (en) | 1992-02-25 |
| WO1992004909A1 (en) | 1992-04-02 |
| GB9020872D0 (en) | 1990-11-07 |
| EP0550529A1 (en) | 1993-07-14 |
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