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NO992907D0 - Flat drug preparation for the application and release of buprenorphine or another pharmacologically comparable substance in the oral cavity and process for its preparation - Google Patents

Flat drug preparation for the application and release of buprenorphine or another pharmacologically comparable substance in the oral cavity and process for its preparation

Info

Publication number
NO992907D0
NO992907D0 NO992907A NO992907A NO992907D0 NO 992907 D0 NO992907 D0 NO 992907D0 NO 992907 A NO992907 A NO 992907A NO 992907 A NO992907 A NO 992907A NO 992907 D0 NO992907 D0 NO 992907D0
Authority
NO
Norway
Prior art keywords
preparation
buprenorphine
release
application
oral cavity
Prior art date
Application number
NO992907A
Other languages
Norwegian (no)
Other versions
NO992907L (en
Inventor
Karsten Cremer
Henrik Luessen
Original Assignee
Lohmann Therapie Syst Lts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lohmann Therapie Syst Lts filed Critical Lohmann Therapie Syst Lts
Publication of NO992907L publication Critical patent/NO992907L/en
Publication of NO992907D0 publication Critical patent/NO992907D0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Addiction (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physiology (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention concerns a solid medicament preparation which can decompose in aqueous media and has a flat-, foil-, paper- or wafer-type presentation for the application and release of active substances in the buccal cavity. The invention is characterized in that it contains buprenorphine, an active substance which is pharmacologically comparable thereto, or a therapeutically suitable salt of buprenorphine or of the pharmacologically comparable active substance.
NO992907A 1996-12-16 1999-06-14 Flat drug preparation for the application and release of buprenorphine or another pharmacologically comparable substance in the oral cavity and process for its preparation NO992907D0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19652188A DE19652188C2 (en) 1996-12-16 1996-12-16 Flat drug preparation for application and release of buprenorphine or a pharmacologically comparable substance in the oral cavity and process for its preparation
PCT/EP1997/006369 WO1998026780A2 (en) 1996-12-16 1997-11-14 Flat medicament preparation for the application and release of buprenorphine or a pharmacologically comparable substance in the buccal cavity, and method of producing the same

Publications (2)

Publication Number Publication Date
NO992907L NO992907L (en) 1999-06-14
NO992907D0 true NO992907D0 (en) 1999-06-14

Family

ID=7814805

Family Applications (1)

Application Number Title Priority Date Filing Date
NO992907A NO992907D0 (en) 1996-12-16 1999-06-14 Flat drug preparation for the application and release of buprenorphine or another pharmacologically comparable substance in the oral cavity and process for its preparation

Country Status (12)

Country Link
EP (1) EP0949925B1 (en)
JP (2) JP2001506640A (en)
KR (1) KR100514306B1 (en)
AT (1) ATE257381T1 (en)
AU (1) AU741362B2 (en)
CA (1) CA2274910C (en)
DE (2) DE19652188C2 (en)
DK (1) DK0949925T3 (en)
ES (1) ES2214649T3 (en)
NO (1) NO992907D0 (en)
PT (1) PT949925E (en)
WO (1) WO1998026780A2 (en)

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US5968547A (en) 1997-02-24 1999-10-19 Euro-Celtique, S.A. Method of providing sustained analgesia with buprenorphine
SE9803240D0 (en) 1998-09-24 1998-09-24 Diabact Ab A pharmaceutical composition having a rapid action
US6596298B2 (en) 1998-09-25 2003-07-22 Warner-Lambert Company Fast dissolving orally comsumable films
WO2000038536A2 (en) 1998-12-23 2000-07-06 Mount Sinai School Of Medicine Of New York University Inhibitors of the bitter taste response
US7314716B2 (en) 1999-11-19 2008-01-01 Mount Sinai School Of Medicine Gustducin γ subunit materials and methods
DE19960154A1 (en) * 1999-12-14 2001-07-12 Lohmann Therapie Syst Lts Flat pharmaceutical preparation for transmucosal administration of oxycodone or a comparable active ingredient in the oral cavity, for use in pain therapy and addiction therapy
US7067116B1 (en) * 2000-03-23 2006-06-27 Warner-Lambert Company Llc Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US8765167B2 (en) 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US7425292B2 (en) 2001-10-12 2008-09-16 Monosol Rx, Llc Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
US8663687B2 (en) 2001-10-12 2014-03-04 Monosol Rx, Llc Film compositions for delivery of actives
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
US20070281003A1 (en) 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
AU2003302589A1 (en) 2002-12-02 2004-06-23 Kyukyu Pharmaceutical Co., Ltd. Method for producing orally administrable edible agent of laminate film form and pressure bonding apparatus of the agent.
DE10338544B4 (en) * 2003-08-19 2017-08-31 Janssen Pharmaceutica N.V. Buccal formulations of galanthamine and their applications
JP4547994B2 (en) 2004-06-02 2010-09-22 救急薬品工業株式会社 Method for producing lump film-containing edible oral dosage form and lump film-containing edible oral dosage form
DE102004045599A1 (en) * 2004-09-17 2006-03-23 Grünenthal GmbH System for the sequential, transdermal administration of systemically active substances
DE102005007859A1 (en) * 2005-02-21 2006-08-24 Lts Lohmann Therapie-Systeme Ag Procedures for a combination drug treatment, as well as suitable drug combinations
EP1968539A2 (en) 2005-12-13 2008-09-17 Biodelivery Sciences International, Inc. Abuse resistant transmucosal drug delivery device
EP1810669A1 (en) * 2006-01-19 2007-07-25 Holger Lars Hermann Application form for burprenorphine
RS54764B1 (en) * 2006-07-21 2016-10-31 Biodelivery Sciences Int Inc TRANSMUCOSCAL DELIVERY MEANS WITH INCREASED PURCHASE
EP1897543A1 (en) * 2006-08-30 2008-03-12 Euro-Celtique S.A. Buprenorphine- wafer for drug substitution therapy
AU2011224107B2 (en) * 2006-08-30 2012-01-19 Euro-Celtique S.A. Buprenophine-wafer for drug substitution therapy
EP2123275A1 (en) 2007-03-15 2009-11-25 Toyo Boseki Kabushiki Kaisha Process for production of buprenorphine pharmaceutical preparation to be applied to mouth mucosa
WO2010008863A1 (en) * 2008-06-23 2010-01-21 Biodelivery Sciences International, Inc. Multidirectional mucosal delivery devices and methods of use
US8475832B2 (en) 2009-08-07 2013-07-02 Rb Pharmaceuticals Limited Sublingual and buccal film compositions
ES2569339T3 (en) 2010-06-10 2016-05-10 Midatech Ltd. Nanoparticle Film Management Systems
US9149959B2 (en) 2010-10-22 2015-10-06 Monosol Rx, Llc Manufacturing of small film strips
KR20210003313A (en) * 2011-12-21 2021-01-11 바이오딜리버리 사이언시스 인터내셔널 인코포레이티드 Transmucosal drug delivery devices for use in chronic pain relief
US9901539B2 (en) 2011-12-21 2018-02-27 Biodelivery Sciences International, Inc. Transmucosal drug delivery devices for use in chronic pain relief
US12427121B2 (en) 2016-05-05 2025-09-30 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine compositions
US12433850B2 (en) 2016-05-05 2025-10-07 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine and prodrug compositions
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
KR20230137362A (en) 2016-05-05 2023-10-04 어퀘스티브 테라퓨틱스, 아이엔씨. Enhanced delivery epinephrine compositions
WO2023076281A1 (en) 2021-10-25 2023-05-04 Aquestive Therapeutics, Inc. Oral and nasal compositions and methods of treatment

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DE2746414A1 (en) * 1977-10-15 1979-04-26 Gerlach Eduard Chem Fab Foil-like tape for dispensing measured amts. of substance - consisting of the substance, binding agent and adjuvants, tape length being proportional to weight of substance
US4315936A (en) * 1979-12-17 1982-02-16 Ortho Pharmaceutical Corporation Analgesic composition
JPS5758615A (en) * 1980-09-26 1982-04-08 Nippon Soda Co Ltd Film agnent and its preparation
CH653550A5 (en) * 1981-10-20 1986-01-15 Sandoz Ag PHARMACEUTICAL COMPOSITION FOR DELAYED RELEASE OF A MEDICINE IN THE ORAL AREA.
JPS58174307A (en) * 1982-04-06 1983-10-13 Teikoku Seiyaku Kk Edible drug for attaching to oral cavity
JPS60116630A (en) * 1983-11-29 1985-06-24 Nitto Electric Ind Co Ltd Pharmaceutical preparation for oral cavity
GB8430346D0 (en) * 1984-11-30 1985-01-09 Reckitt & Colmann Prod Ltd Analgesic compositions
ES2019275B3 (en) * 1985-10-09 1991-06-16 Desitin Arzneimittel Gmbh METHOD FOR THE PRODUCTION OF A METHOD OF ADMINISTRATION AND DOSAGE FOR REACTIVE DRUGS OR OTHER ACTIVE PRINCIPLES.
US4722928A (en) * 1985-12-02 1988-02-02 E. I. Du Pont De Nemours And Company N-oxide prodrug derivatives of 3-hydroxy morphinans and partial morphinans having improved oral bioavailability, pharmaceutical compositions, and processes
JPH07553B2 (en) * 1985-12-09 1995-01-11 佐藤製薬株式会社 Film preparation
US4673679A (en) * 1986-05-14 1987-06-16 E. I. Du Pont De Nemours And Company Use of prodrugs of 3-hydroxymorphinans to prevent bitter taste upon buccal, nasal or sublingual administration
JPH0744940B2 (en) * 1986-12-24 1995-05-17 ライオン株式会社 Base material for oral application
JPH0653683B2 (en) * 1988-07-14 1994-07-20 ザ ロックフェラー ユニバーシティ Oral composition for treating chronic pain or cough
JP2879695B2 (en) * 1990-02-22 1999-04-05 日本曹達株式会社 Oral mucosa-adhesive film preparation
JP2669951B2 (en) * 1991-03-28 1997-10-29 雍憲 森本 Transdermal composition containing narcotic analgesic
JP3197035B2 (en) * 1991-12-10 2001-08-13 積水化学工業株式会社 Formulation for oral mucosa
IL110014A (en) * 1993-07-01 1999-11-30 Euro Celtique Sa Solid controlled-release oral dosage forms of opioid analgesics
JP3731612B2 (en) * 1995-04-21 2006-01-05 東洋紡績株式会社 Oral mucosa buprenorphine preparation

Also Published As

Publication number Publication date
DE19652188C2 (en) 2002-02-14
AU5653298A (en) 1998-07-15
EP0949925B1 (en) 2004-01-07
WO1998026780A2 (en) 1998-06-25
ATE257381T1 (en) 2004-01-15
CA2274910C (en) 2005-07-05
WO1998026780A3 (en) 1998-08-27
DK0949925T3 (en) 2004-04-05
KR100514306B1 (en) 2005-09-13
DE59711194D1 (en) 2004-02-12
KR20000057566A (en) 2000-09-25
NO992907L (en) 1999-06-14
EP0949925A2 (en) 1999-10-20
PT949925E (en) 2004-05-31
AU741362B2 (en) 2001-11-29
JP2001506640A (en) 2001-05-22
CA2274910A1 (en) 1998-06-25
ES2214649T3 (en) 2004-09-16
JP2009242415A (en) 2009-10-22
DE19652188A1 (en) 1998-06-18

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application