NO994898L - Cytomodulering av lipofile peptider for å modulere immunsystemaktivitet og inhibere inflammasjon - Google Patents
Cytomodulering av lipofile peptider for å modulere immunsystemaktivitet og inhibere inflammasjonInfo
- Publication number
- NO994898L NO994898L NO994898A NO994898A NO994898L NO 994898 L NO994898 L NO 994898L NO 994898 A NO994898 A NO 994898A NO 994898 A NO994898 A NO 994898A NO 994898 L NO994898 L NO 994898L
- Authority
- NO
- Norway
- Prior art keywords
- cells
- activity
- lymphocytic
- inhibiting
- inhibit
- Prior art date
Links
- 206010061218 Inflammation Diseases 0.000 title 1
- 230000005965 immune activity Effects 0.000 title 1
- 230000004054 inflammatory process Effects 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 5
- 230000000527 lymphocytic effect Effects 0.000 abstract 4
- 102000004127 Cytokines Human genes 0.000 abstract 3
- 108090000695 Cytokines Proteins 0.000 abstract 3
- 230000000694 effects Effects 0.000 abstract 3
- 230000002401 inhibitory effect Effects 0.000 abstract 3
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 150000003278 haem Chemical class 0.000 abstract 2
- 230000002757 inflammatory effect Effects 0.000 abstract 2
- 230000028709 inflammatory response Effects 0.000 abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- 102000015636 Oligopeptides Human genes 0.000 abstract 1
- 108010038807 Oligopeptides Proteins 0.000 abstract 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 1
- 230000000735 allogeneic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000004590 computer program Methods 0.000 abstract 1
- 230000009089 cytolysis Effects 0.000 abstract 1
- 230000001472 cytotoxic effect Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83891697A | 1997-04-11 | 1997-04-11 | |
| US09/028,083 US6696545B1 (en) | 1997-04-11 | 1998-02-23 | Cytomodulating lipophilic peptides for modulating immune system activity and inhibiting inflammation |
| PCT/US1998/007231 WO1998046633A1 (en) | 1997-04-11 | 1998-04-10 | Cytomodulating lipophilic peptides for modulating immune system activity and inhibiting inflammation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO994898D0 NO994898D0 (no) | 1999-10-08 |
| NO994898L true NO994898L (no) | 1999-11-24 |
Family
ID=26703275
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO994898A NO994898L (no) | 1997-04-11 | 1999-10-08 | Cytomodulering av lipofile peptider for å modulere immunsystemaktivitet og inhibere inflammasjon |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7267822B2 (no) |
| EP (1) | EP0973799B1 (no) |
| JP (1) | JP4550171B2 (no) |
| CN (1) | CN1216900C (no) |
| AT (1) | ATE352556T1 (no) |
| AU (2) | AU761717B2 (no) |
| BR (1) | BR9808529B1 (no) |
| CA (1) | CA2286478A1 (no) |
| IL (1) | IL132310A0 (no) |
| NO (1) | NO994898L (no) |
| NZ (1) | NZ500287A (no) |
| PL (1) | PL336302A1 (no) |
| TR (1) | TR199902786T2 (no) |
| WO (1) | WO1998046633A1 (no) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2773240B1 (fr) | 1997-12-30 | 2002-11-29 | Synt Em | Procede pour prevoir, identifier et decrire des molecules susceptibles de presenter un comportement recherche, notamment dans le domaine de la pharmacie et molecules obtenues par ce procede |
| AU4650500A (en) * | 1999-04-21 | 2000-11-02 | Baylor College Of Medicine | Cysteine protease and inhibitors for prevention and treatment of neurocysticerocosis |
| WO2003061602A2 (en) | 2002-01-24 | 2003-07-31 | Sangstat Medical Corporation | Combination therapy for treatment of hiv infection |
| IL163718A0 (en) * | 2002-02-26 | 2005-12-18 | Ngstat Medical Corp | Methods and compositions for treating gastrointestinal toxicity induced by cytoablative therapy |
| FR2842738B1 (fr) * | 2002-07-23 | 2006-02-10 | Negma Lerads | Utilisation d'une rheine pour la preparation d'un medicament pour le traitement de l'inflammation chronique, la prevention et le traitement du rejet des transplantations d'organes et de tissus |
| RU2005118425A (ru) * | 2002-11-15 | 2006-02-10 | Сэнгстат Медикал Корпорейшн (Us) | Цитомодуляторные пептиды для лечения интерстициального цистита |
| WO2005009457A1 (en) * | 2003-05-15 | 2005-02-03 | Sangstat Medical Corporation | Rdp58 compositions and methods for inhibiting vascularization of cell populations |
| WO2005001075A1 (en) * | 2003-05-15 | 2005-01-06 | Sangstat Medical Corporation | Rdp58 compositions and methods for modulating the activity of osteoclasts and osteoblasts |
| US7498309B2 (en) | 2003-11-29 | 2009-03-03 | Sangstat Medical Corporation | Pharmaceutical compositions for bioactive peptide agents |
| CN104231054A (zh) * | 2014-09-01 | 2014-12-24 | 王跃建 | Il-10多肽抑制剂 |
| GB201918167D0 (en) * | 2019-12-11 | 2020-01-22 | Univ Newcastle | Collagen production |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5888512A (en) * | 1987-01-30 | 1999-03-30 | Board Of Trustees Of The Leland Stanford Junior University | Lymphocyte activity regulation by HLA peptides |
| AU619458B2 (en) | 1987-01-30 | 1992-01-30 | Board Of Trustees Of The Leland Stanford Junior University | Lymphocyte inhibition by hla peptides |
| US5723128A (en) * | 1987-01-30 | 1998-03-03 | The Board Of Trustees Of The Leland Stanford Junior University | Cytotoxic T-cell lymphocyte ("CTL") activity regulation by class I MHC peptides |
| US5385888A (en) * | 1987-03-20 | 1995-01-31 | The Regents Of The University Of California | Class I MHC modulation or surface receptor activity |
| WO1990010016A1 (en) | 1989-03-03 | 1990-09-07 | The Regents Of The University Of California | Class i mhc modulation of surface receptor activity |
| CA2115839C (en) * | 1991-08-26 | 2010-06-01 | Maria A. Vitiello | Hla-restricted hepatitis b virus ctl epitopes |
| EP0661985B1 (en) | 1991-11-08 | 1999-07-07 | The Board Of Trustees Of The Leland Stanford Junior University | Peptides capable of binding cd8 molecules on ctl precursors |
| US5440015A (en) | 1992-07-21 | 1995-08-08 | Glycomed Incorporated | Selectin peptide medicaments for treating disease |
| US6828415B2 (en) * | 1993-02-19 | 2004-12-07 | Zentaris Gmbh | Oligopeptide lyophilisate, their preparation and use |
| JPH09508617A (ja) * | 1993-11-10 | 1997-09-02 | ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ | 表面膜タンパク質および免疫応答に対するそれらの影響 |
| US5707622A (en) * | 1994-03-03 | 1998-01-13 | Genentech, Inc. | Methods for treating ulcerative colitis |
| AU694602B2 (en) * | 1995-01-16 | 1998-07-23 | Northern Sydney And Central Coast Area Health Service | Novel peptide |
| US6162434A (en) * | 1995-05-03 | 2000-12-19 | Sangstat Medical Corporation | Cytomodulating peptide for inhibiting lymphocyte activity |
| US5753625A (en) * | 1995-05-12 | 1998-05-19 | Sangstat Medical Corporation | Treatment for inhibiting the progression of autoimmune disease |
| WO1997024140A1 (en) | 1996-01-02 | 1997-07-10 | The Board Of Trustees Of Leland Stanford Junior University | Interaction of hla proteins with members of the hsp70 family of proteins |
| US6436903B1 (en) | 1996-05-22 | 2002-08-20 | Stanford University (Board Of Trustees Of The Leland Standford Junior University) | Immunomodulating compounds comprising d-isomers of amino acids |
| WO1997044351A1 (en) | 1996-05-24 | 1997-11-27 | The Board Of Trustees Of Leland Stanford Junior University | Immunomodulating dimers |
| US6696545B1 (en) * | 1997-04-11 | 2004-02-24 | Sangstat Medical Corporation | Cytomodulating lipophilic peptides for modulating immune system activity and inhibiting inflammation |
-
1998
- 1998-04-10 CN CN98806071XA patent/CN1216900C/zh not_active Expired - Fee Related
- 1998-04-10 CA CA002286478A patent/CA2286478A1/en not_active Abandoned
- 1998-04-10 AT AT98914676T patent/ATE352556T1/de not_active IP Right Cessation
- 1998-04-10 NZ NZ500287A patent/NZ500287A/xx not_active Application Discontinuation
- 1998-04-10 WO PCT/US1998/007231 patent/WO1998046633A1/en not_active Ceased
- 1998-04-10 BR BRPI9808529-8A patent/BR9808529B1/pt not_active IP Right Cessation
- 1998-04-10 EP EP98914676A patent/EP0973799B1/en not_active Expired - Lifetime
- 1998-04-10 TR TR1999/02786T patent/TR199902786T2/xx unknown
- 1998-04-10 JP JP54410298A patent/JP4550171B2/ja not_active Expired - Fee Related
- 1998-04-10 PL PL98336302A patent/PL336302A1/xx not_active Application Discontinuation
- 1998-04-10 IL IL13231098A patent/IL132310A0/xx unknown
- 1998-04-10 AU AU68978/98A patent/AU761717B2/en not_active Ceased
-
1999
- 1999-10-08 NO NO994898A patent/NO994898L/no not_active Application Discontinuation
-
2003
- 2003-09-05 AU AU2003244571A patent/AU2003244571B2/en not_active Ceased
-
2004
- 2004-02-17 US US10/780,321 patent/US7267822B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE352556T1 (de) | 2007-02-15 |
| AU2003244571A1 (en) | 2003-10-02 |
| EP0973799B1 (en) | 2007-01-24 |
| US20040248810A1 (en) | 2004-12-09 |
| CN1259958A (zh) | 2000-07-12 |
| AU6897898A (en) | 1998-11-11 |
| EP0973799A1 (en) | 2000-01-26 |
| PL336302A1 (en) | 2000-06-19 |
| TR199902786T2 (xx) | 2000-06-21 |
| NO994898D0 (no) | 1999-10-08 |
| AU2003244571B2 (en) | 2007-07-05 |
| NZ500287A (en) | 2002-10-25 |
| WO1998046633A1 (en) | 1998-10-22 |
| US7267822B2 (en) | 2007-09-11 |
| BR9808529A (pt) | 2000-10-24 |
| BR9808529B1 (pt) | 2010-10-05 |
| JP2001526641A (ja) | 2001-12-18 |
| AU761717B2 (en) | 2003-06-05 |
| JP4550171B2 (ja) | 2010-09-22 |
| CA2286478A1 (en) | 1998-10-22 |
| CN1216900C (zh) | 2005-08-31 |
| IL132310A0 (en) | 2001-03-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |