NO994671D0 - Aryl- eller heteroarylsulfonamid-substituerte hydroksamsyrederivater, fremgangsmaate til fremstillint derav og deres anvendelse som farmasöytika - Google Patents
Aryl- eller heteroarylsulfonamid-substituerte hydroksamsyrederivater, fremgangsmaate til fremstillint derav og deres anvendelse som farmasöytikaInfo
- Publication number
- NO994671D0 NO994671D0 NO994671A NO994671A NO994671D0 NO 994671 D0 NO994671 D0 NO 994671D0 NO 994671 A NO994671 A NO 994671A NO 994671 A NO994671 A NO 994671A NO 994671 D0 NO994671 D0 NO 994671D0
- Authority
- NO
- Norway
- Prior art keywords
- heteroarylsulfonamide
- pharmaceuticals
- aryl
- processes
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9706255.8A GB9706255D0 (en) | 1997-03-26 | 1997-03-26 | Novel compounds |
| PCT/EP1998/001766 WO1998042659A2 (en) | 1997-03-26 | 1998-03-16 | Aryl- or heteroarylsulfonamide substituted hydroxamic acid derivates, process for their preparation and their use as pharmaceuticals |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO994671D0 true NO994671D0 (no) | 1999-09-24 |
| NO994671L NO994671L (no) | 1999-09-24 |
Family
ID=10809882
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO994671A NO994671L (no) | 1997-03-26 | 1999-09-24 | Aryl- eller heteroarylsulfonamid-substituerte hydroksamsyrederivater, fremgangsmåte til fremstilling derav og deres anvendelse som farmasöytika |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6242467B1 (no) |
| EP (1) | EP0973732A2 (no) |
| JP (1) | JP2001518922A (no) |
| KR (1) | KR20010005627A (no) |
| CN (1) | CN1251091A (no) |
| AR (1) | AR012294A1 (no) |
| AU (1) | AU7210598A (no) |
| BR (1) | BR9808366A (no) |
| CA (1) | CA2285439A1 (no) |
| CO (1) | CO4950563A1 (no) |
| GB (1) | GB9706255D0 (no) |
| HU (1) | HUP0003021A3 (no) |
| IL (1) | IL131751A0 (no) |
| NO (1) | NO994671L (no) |
| PL (1) | PL336039A1 (no) |
| TR (1) | TR199902357T2 (no) |
| WO (1) | WO1998042659A2 (no) |
| ZA (1) | ZA982517B (no) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5904697A (en) * | 1995-02-24 | 1999-05-18 | Heartport, Inc. | Devices and methods for performing a vascular anastomosis |
| WO1999006340A2 (en) | 1997-07-31 | 1999-02-11 | The Procter & Gamble Company | Sulfonylamino substituted hydroxamic acid derivatives as metalloprotease inhibitors |
| US6403632B1 (en) * | 2000-03-01 | 2002-06-11 | Bristol Myers Squibb Pharma Co | Lactam metalloprotease inhibitors |
| US6313123B1 (en) | 1999-01-27 | 2001-11-06 | American Cyanamid Company | Acetylenic sulfonamide thiol tace inhibitors |
| US6340691B1 (en) | 1999-01-27 | 2002-01-22 | American Cyanamid Company | Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase and tace inhibitors |
| US6277885B1 (en) | 1999-01-27 | 2001-08-21 | American Cyanamid Company | Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors |
| US6326516B1 (en) | 1999-01-27 | 2001-12-04 | American Cyanamid Company | Acetylenic β-sulfonamido and phosphinic acid amide hydroxamic acid TACE inhibitors |
| US6200996B1 (en) | 1999-01-27 | 2001-03-13 | American Cyanamid Company | Heteroaryl acetylenic sulfonamide and phosphinic acid amide hydroxamic acid tace inhibitors |
| US6946473B2 (en) | 1999-01-27 | 2005-09-20 | Wyeth Holdings Corporation | Preparation and use of acetylenic ortho-sulfonamido and phosphinic acid amido bicyclic heteroaryl hydroxamic acids as TACE inhibitors |
| WO2000044723A1 (en) | 1999-01-27 | 2000-08-03 | American Cyanamid Company | Alkynyl containing hydroxamic acid derivatives, their preparation and their use as matrix metalloproteinase (mmp) inhibitors/tnf-alpha converting enzyme (tace) inhibitors |
| US6762178B2 (en) | 1999-01-27 | 2004-07-13 | Wyeth Holdings Corporation | Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors |
| US6225311B1 (en) | 1999-01-27 | 2001-05-01 | American Cyanamid Company | Acetylenic α-amino acid-based sulfonamide hydroxamic acid tace inhibitors |
| US6753337B2 (en) | 1999-01-27 | 2004-06-22 | Wyeth Holdings Corporation | Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase/tace inhibitors |
| CN1362951A (zh) | 1999-03-03 | 2002-08-07 | 宝洁公司 | 二杂-取代的金属蛋白酶抑制剂 |
| EP1165501A1 (en) | 1999-03-03 | 2002-01-02 | The Procter & Gamble Company | Alkenyl- and alkynyl-containing metalloprotease inhibitors |
| GB9922825D0 (en) * | 1999-09-25 | 1999-11-24 | Smithkline Beecham Biolog | Medical use |
| US6808902B1 (en) | 1999-11-12 | 2004-10-26 | Amgen Inc. | Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules |
| JP2003523994A (ja) * | 2000-02-24 | 2003-08-12 | スミスクライン ビーチャム パブリック リミテッド カンパニー | 新規cd23インヒビター |
| NZ522594A (en) * | 2000-05-25 | 2004-05-28 | Smithkline Beecham P | Bicyclyl or heterobicyclylmethanesulfonylamino-substituted N-hydroxyformamides |
| DK2270052T3 (en) | 2001-06-26 | 2018-07-02 | Amgen Inc | Antibodies to OPGL |
| CN1610661A (zh) | 2001-11-01 | 2005-04-27 | 惠氏控股公司 | 用作基质金属蛋白酶和tace的抑制剂的丙二烯芳基磺酰胺异羟肟酸 |
| GB0128376D0 (en) * | 2001-11-27 | 2002-01-16 | Smithkline Beecham Plc | Novel compounds |
| US7421862B2 (en) * | 2001-12-27 | 2008-09-09 | Lg Electronics Inc. | Washing machine with temperature sensor arrangement |
| US7504425B2 (en) | 2002-05-29 | 2009-03-17 | Merck & Co., Inc. | Compounds useful in the treatment of anthrax and inhibiting lethal factor |
| AU2003304456A1 (en) | 2002-12-23 | 2005-03-16 | Wyeth Holdings Corporation | Acetylenic aryl sulfonate hydroxamic acid tace and matrix metalloproteinase inhibitors |
| AU2005250351A1 (en) | 2004-05-11 | 2005-12-15 | Merck & Co., Inc. | Process for making n-sulfonated-amino acid derivatives |
| JP2011528013A (ja) * | 2008-07-14 | 2011-11-10 | ノバルティス アーゲー | ヒドロキサム酸系の選択的mmp−12およびmmp−13阻害剤 |
| USD810196S1 (en) * | 2015-04-14 | 2018-02-13 | Marcia D. Fackler | Sunglass book cover |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5455258A (en) | 1993-01-06 | 1995-10-03 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamic acids |
| DK0766664T3 (da) | 1994-06-22 | 2000-07-31 | British Biotech Pharm | Metalloproteinaseinhibitorer |
| GB9414157D0 (en) | 1994-07-13 | 1994-08-31 | Smithkline Beecham Plc | Medical use |
| BR9609883A (pt) * | 1995-08-08 | 1999-03-23 | Fibrogen Inc | Composto tendo efeito inibidor em proteinase c composição farmacéutica e processo para tratar doenças relacionadas com a produção inapropriada ou desregulada de colágeno |
| PT757984E (pt) | 1995-08-08 | 2003-02-28 | Ono Pharmaceutical Co | Derivados de acido hidroxamico uteis para inibir a gelatinase |
| EP0901466B1 (en) | 1996-05-17 | 2001-10-31 | Warner-Lambert Company | Biphenylsulfonamide matrix metalloproteinase inhibitors |
| EP0931045A1 (en) * | 1996-09-04 | 1999-07-28 | Warner-Lambert Company | Matrix metalloproteinase inhibitors and their therapeutic uses |
-
1997
- 1997-03-26 GB GBGB9706255.8A patent/GB9706255D0/en active Pending
-
1998
- 1998-03-16 KR KR1019997008694A patent/KR20010005627A/ko not_active Withdrawn
- 1998-03-16 US US09/381,405 patent/US6242467B1/en not_active Expired - Fee Related
- 1998-03-16 EP EP98919153A patent/EP0973732A2/en not_active Withdrawn
- 1998-03-16 PL PL98336039A patent/PL336039A1/xx unknown
- 1998-03-16 JP JP54489898A patent/JP2001518922A/ja active Pending
- 1998-03-16 CN CN98803639A patent/CN1251091A/zh active Pending
- 1998-03-16 CA CA002285439A patent/CA2285439A1/en not_active Abandoned
- 1998-03-16 AU AU72105/98A patent/AU7210598A/en not_active Abandoned
- 1998-03-16 TR TR1999/02357T patent/TR199902357T2/xx unknown
- 1998-03-16 BR BR9808366-0A patent/BR9808366A/pt not_active Application Discontinuation
- 1998-03-16 WO PCT/EP1998/001766 patent/WO1998042659A2/en not_active Ceased
- 1998-03-16 IL IL13175198A patent/IL131751A0/xx unknown
- 1998-03-16 HU HU0003021A patent/HUP0003021A3/hu unknown
- 1998-03-24 AR ARP980101342A patent/AR012294A1/es unknown
- 1998-03-25 ZA ZA9802517A patent/ZA982517B/xx unknown
- 1998-03-26 CO CO98016978A patent/CO4950563A1/es unknown
-
1999
- 1999-09-24 NO NO994671A patent/NO994671L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ZA982517B (en) | 1999-09-27 |
| WO1998042659A2 (en) | 1998-10-01 |
| PL336039A1 (en) | 2000-06-05 |
| HUP0003021A2 (hu) | 2002-01-28 |
| JP2001518922A (ja) | 2001-10-16 |
| HUP0003021A3 (en) | 2002-02-28 |
| IL131751A0 (en) | 2001-03-19 |
| BR9808366A (pt) | 2000-05-23 |
| US6242467B1 (en) | 2001-06-05 |
| CO4950563A1 (es) | 2000-09-01 |
| EP0973732A2 (en) | 2000-01-26 |
| TR199902357T2 (xx) | 2000-05-22 |
| WO1998042659A3 (en) | 1999-02-25 |
| AU7210598A (en) | 1998-10-20 |
| CA2285439A1 (en) | 1998-10-01 |
| GB9706255D0 (en) | 1997-05-14 |
| CN1251091A (zh) | 2000-04-19 |
| NO994671L (no) | 1999-09-24 |
| KR20010005627A (ko) | 2001-01-15 |
| AR012294A1 (es) | 2000-10-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |