NO981121L - Substituerte aminoforbindelser og deres anvendelse som analgetisk virksomme stoffer - Google Patents
Substituerte aminoforbindelser og deres anvendelse som analgetisk virksomme stofferInfo
- Publication number
- NO981121L NO981121L NO981121A NO981121A NO981121L NO 981121 L NO981121 L NO 981121L NO 981121 A NO981121 A NO 981121A NO 981121 A NO981121 A NO 981121A NO 981121 L NO981121 L NO 981121L
- Authority
- NO
- Norway
- Prior art keywords
- active substances
- substituted amino
- amino compounds
- analgesically active
- analgesically
- Prior art date
Links
- 239000013543 active substance Substances 0.000 title 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
- C07C215/54—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/28—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by unsaturated carbon chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/12—One of the condensed rings being a six-membered aromatic ring the other ring being at least seven-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19710628 | 1997-03-14 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO981121D0 NO981121D0 (no) | 1998-03-13 |
| NO981121L true NO981121L (no) | 1998-09-15 |
| NO311128B1 NO311128B1 (no) | 2001-10-15 |
Family
ID=7823396
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19981121A NO311128B1 (no) | 1997-03-14 | 1998-03-13 | Substituerte aminoforbindelser, fremgangsmåte for fremstilling derav samt anvendelse av forbindelsene |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US6022895A (no) |
| EP (1) | EP0864559B1 (no) |
| JP (1) | JP4132189B2 (no) |
| KR (1) | KR100579428B1 (no) |
| CN (1) | CN1243721C (no) |
| AR (1) | AR010129A1 (no) |
| AT (1) | ATE218534T1 (no) |
| AU (1) | AU728501B2 (no) |
| CA (1) | CA2231975C (no) |
| CO (1) | CO4940510A1 (no) |
| CZ (1) | CZ295522B6 (no) |
| DE (2) | DE19805370A1 (no) |
| DK (1) | DK0864559T3 (no) |
| ES (1) | ES2178055T3 (no) |
| HU (1) | HU226060B1 (no) |
| IL (1) | IL123647A (no) |
| MY (1) | MY118828A (no) |
| NO (1) | NO311128B1 (no) |
| NZ (1) | NZ329951A (no) |
| PE (1) | PE59899A1 (no) |
| PL (1) | PL191727B1 (no) |
| PT (1) | PT864559E (no) |
| RU (1) | RU2197474C2 (no) |
| SI (1) | SI0864559T1 (no) |
| SK (1) | SK284279B6 (no) |
| UA (1) | UA56997C2 (no) |
| UY (1) | UY24919A1 (no) |
| ZA (1) | ZA982157B (no) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19830105C1 (de) * | 1998-07-06 | 2000-02-17 | Gruenenthal Gmbh | Acridinderivate |
| DE19963179B4 (de) * | 1999-12-27 | 2009-02-05 | Grünenthal GmbH | Substituierte 1- und 2-Naphthol-Mannichbasen |
| DE10033459A1 (de) * | 2000-07-10 | 2002-01-24 | Gruenenthal Gmbh | Cyclische substituierte Aminomethylverbindungen und diese Verbindungen enthaltende Arzeimittel |
| NZ531679A (en) | 2001-10-15 | 2005-02-25 | Janssen Pharmaceutica Nv | Novel substituted 4-phenyl-4-[1H-imidazol-2-YL]-piperidine derivatives and their use as selective non-peptide delta opioid agonists |
| DE10206405A1 (de) * | 2002-02-14 | 2003-08-28 | Gruenenthal Gmbh | Synthese von substituierten Carbamidestern |
| DE10206403A1 (de) * | 2002-02-14 | 2003-08-28 | Gruenenthal Gmbh | Synthese von Beta-Aminoketonen |
| CL2004000754A1 (es) * | 2003-04-11 | 2005-02-25 | Janssen Pharmaceutica Nv | Uso de compuestos derivados de 4-fenil-4-(1h-imidazol-2-il)piperidina, como agonistas delta-opioides no peptidicos, para preparar un medicamento util en prevenir o tratar trastornos del sistema nervioso central. |
| DE10341534A1 (de) * | 2003-09-09 | 2005-03-31 | Bayer Chemicals Ag | Difluoralkylaromaten |
| US8067603B2 (en) * | 2003-09-25 | 2011-11-29 | Solvay Pharmaceuticals B.V. | Benzimidazolone and quinazolinone derivatives as agonists on human ORL1 receptors |
| BRPI0415165A (pt) | 2003-10-01 | 2007-01-09 | Adolor Corp | composto heterocìclico espirocìclico, composição farmacêutica, método para ligar receptores opióides, métodos para prevenir ou tratar dor, disfunção gastrointestinal, um distúrbio do trato urogenital, um distúrbio imunomodulatório, um distúrbio inflamatório, um distúrbio de função respiratória, ansiedade, distúrbio do humor, um distúrbio relacionado a estresse, distúrbio do sistema nervoso simpático, tosse, e um distúrbio motor, método para tratar uma lesão traumática ao sistema nervoso central, métodos para prevenir ou tratar acidente vascular, arritmia cardìaca, glaucoma, e disfunção sexual, métodos para tratar uma condição selecionada do grupo consistindo de choque, edema cerebral, isquemia cerebral, déficit cerebral após cirurgia cardìaca (bypass) e enxerto, lupus eritematoso sistêmico, doença de hodgkin, doença de sjogren, epilepsia, e rejeição em transplantes de órgão e enxertos de pele, e para tratar dependência de substáncias, métodos para melhorar a sobrevivência de órgãos e células, e cardioproteção após infarto do miocárdio, métodos para reduzir a necessidade de anestesia, para produzir ou manter um estado anestésico, derivado radiomarcado de um composto, derivado isotopicamente marcado de um composto, composto e método de diagnóstico por imagem |
| DE102004030099A1 (de) * | 2004-06-22 | 2006-01-12 | Grünenthal GmbH | Gesättigte und ungesättigte 3-Pyridyl-benzocycloalkylmethyl-amine als Serotonin- und/oder Noradrenalin-Reuptake-Hemmer und/oder µ-Opioidrezeptor-Modulatoren |
| WO2006023757A2 (en) * | 2004-08-19 | 2006-03-02 | University Of Virginia Patent Foundation | Novel tricyclic, bicyclic, monocyclic, and acyclic amines as potent sodium channel blocking agents |
| US7598261B2 (en) | 2005-03-31 | 2009-10-06 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| RU2320342C2 (ru) * | 2005-07-27 | 2008-03-27 | ГУ Научно-исследовательский институт кардиологии Томского научного центра Сибирского отделения Российской академии медицинских наук, ГУ НИИ кардиологии ТНЦ СО РАМН | Антиаритмическое средство |
| JP5090639B2 (ja) | 2005-11-18 | 2012-12-05 | 出光興産株式会社 | 芳香族アミン誘導体及びそれを用いた有機エレクトロルミネッセンス素子 |
| US7576207B2 (en) | 2006-04-06 | 2009-08-18 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| TWI401237B (zh) * | 2006-07-24 | 2013-07-11 | ３-〔（１ｒ，２ｒ）-３-（二甲基氨基）-１-乙基-２-甲基丙基〕酚之製備 | |
| AU2007294968A1 (en) | 2006-09-12 | 2008-03-20 | Adolor Corporation | Use of N-containing spirocompounds for the enhancement of cognitive function |
| TW200901961A (en) * | 2007-02-16 | 2009-01-16 | Synta Pharmaceuticals Corp | Substituted fused-ring compounds for inflammation and immune-related uses |
| WO2012100423A1 (en) * | 2011-01-27 | 2012-08-02 | Eli Lilly And Company | Analgesic compounds, methods, and formulations |
| RU2538727C1 (ru) * | 2013-11-15 | 2015-01-10 | Закрытое акционерное общество "Институт экспериментальной фармакологии" | Анальгетическое средство пептидной структуры на основе тридекапептида, содержащего d-октааргининовый вектор |
| CN104844471B (zh) * | 2015-04-21 | 2017-05-03 | 苏州远智医药科技有限公司 | 一种作为dor受体拮抗剂的化合物 |
| CN109896991B (zh) * | 2017-12-08 | 2020-11-20 | 苏州远智医药科技有限公司 | 一种δ阿片受体拮抗剂及其用途和药物组合物 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE623394A (no) * | ||||
| GB872371A (en) * | 1958-07-07 | 1961-07-05 | Univ Kansas Reseach Foundation | Benzyl amine compounds and means of obtaining the same |
| GB956616A (en) * | 1961-10-10 | 1964-04-29 | Koninklijke Pharma Fab Nv | New substituted diphenylalkylamines |
| DE1203247B (de) * | 1961-10-10 | 1965-10-21 | Koninklijke Pharma Fab Nv | Verfahren zur Herstellung von Diphenylalkenyl-aminen sowie deren nicht-toxischen Salzen |
| DE1149002B (de) * | 1961-10-19 | 1963-05-22 | Giulini Gmbh Geb | Verfahren zur Herstellung von blutdrucksteigernden Salzen von N, N-Dialkyl-2-aethyl-3, 3-diphenyl-propen-(2)-yl-aminen |
| US3452094A (en) * | 1967-07-19 | 1969-06-24 | Geigy Chem Corp | N - 2 - phenyl - 2 - (2 - hydroxy - 1 - naphthyl) ethyl-n-substituted amines and salts thereof |
| RU2005717C1 (ru) * | 1989-02-17 | 1994-01-15 | Такеда кемикал-индастриз Лтд | Способ получения производных аралкиламинов или их кислотно-аддитивных солей |
| ATE267009T1 (de) * | 1993-02-23 | 2004-06-15 | Brigham & Womens Hospital | Calciumrezeptoraktive moleküle |
-
1998
- 1998-02-11 DE DE19805370A patent/DE19805370A1/de not_active Withdrawn
- 1998-02-19 PT PT98102853T patent/PT864559E/pt unknown
- 1998-02-19 SI SI9830137T patent/SI0864559T1/xx unknown
- 1998-02-19 EP EP98102853A patent/EP0864559B1/de not_active Expired - Lifetime
- 1998-02-19 AT AT98102853T patent/ATE218534T1/de active
- 1998-02-19 DE DE59804276T patent/DE59804276D1/de not_active Expired - Lifetime
- 1998-02-19 DK DK98102853T patent/DK0864559T3/da active
- 1998-02-19 ES ES98102853T patent/ES2178055T3/es not_active Expired - Lifetime
- 1998-03-09 UY UY24919A patent/UY24919A1/es not_active Application Discontinuation
- 1998-03-09 MY MYPI98001021A patent/MY118828A/en unknown
- 1998-03-11 AR ARP980101094A patent/AR010129A1/es unknown
- 1998-03-11 CO CO98013443A patent/CO4940510A1/es unknown
- 1998-03-11 US US09/038,033 patent/US6022895A/en not_active Expired - Lifetime
- 1998-03-12 UA UA98031284A patent/UA56997C2/uk unknown
- 1998-03-12 CZ CZ1998755A patent/CZ295522B6/cs not_active IP Right Cessation
- 1998-03-12 CA CA002231975A patent/CA2231975C/en not_active Expired - Fee Related
- 1998-03-12 NZ NZ329951A patent/NZ329951A/en unknown
- 1998-03-12 SK SK333-98A patent/SK284279B6/sk not_active IP Right Cessation
- 1998-03-12 PE PE1998000170A patent/PE59899A1/es not_active Application Discontinuation
- 1998-03-12 IL IL12364798A patent/IL123647A/en not_active IP Right Cessation
- 1998-03-12 CN CNB981078680A patent/CN1243721C/zh not_active Expired - Fee Related
- 1998-03-12 RU RU98105507/04A patent/RU2197474C2/ru active
- 1998-03-13 KR KR1019980008435A patent/KR100579428B1/ko not_active Expired - Fee Related
- 1998-03-13 ZA ZA982157A patent/ZA982157B/xx unknown
- 1998-03-13 AU AU58408/98A patent/AU728501B2/en not_active Ceased
- 1998-03-13 NO NO19981121A patent/NO311128B1/no unknown
- 1998-03-13 JP JP06350098A patent/JP4132189B2/ja not_active Expired - Fee Related
- 1998-03-13 HU HU9800555A patent/HU226060B1/hu not_active IP Right Cessation
- 1998-03-13 PL PL325322A patent/PL191727B1/pl not_active IP Right Cessation
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