NO980333D0 - (R)-5-brom-N-(1-etyl-4-metylheksahydro-1H-1,4-diazepin-6-yl)-2-metoksy-6-metylamino-3-pyridinkarboksamid, fremgangsmåte ved fremstilling derav og farmasöytisk sammensetning inneholdende forbindelsen - Google Patents

(R)-5-brom-N-(1-etyl-4-metylheksahydro-1H-1,4-diazepin-6-yl)-2-metoksy-6-metylamino-3-pyridinkarboksamid, fremgangsmåte ved fremstilling derav og farmasöytisk sammensetning inneholdende forbindelsen

Info

Publication number: NO980333D0
Authority: NO; Norway
Prior art keywords: compound; methylhexahydro; pyridinecarboxamide; diazepin; methylamino
Prior art date: 1995-07-28

Application number

NO980333A

Other languages

English (en)

Other versions

NO312964B1 (no

NO980333L (no

Inventor

Shiro Kato

Yoshimi Hirokawa

Toshiya Morie

Hiroshi Harada

Naoyuki Yoshida

Original Assignee

Dainippon Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-07-28

Filing date

1998-01-26

Publication date

1998-01-26

1998-01-26 Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co

1998-01-26 Publication of NO980333D0 publication Critical patent/NO980333D0/no

1998-03-23 Publication of NO980333L publication Critical patent/NO980333L/no

2002-07-22 Publication of NO312964B1 publication Critical patent/NO312964B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO19980333A 1995-07-28 1998-01-26 (R)-5-brom-N-(1-etyl-4-metylheksahydro-1H-1,4-diazepin-6-yl)- 2-metoksy-6-metylamino-3-pyridinkarboksamid, fremgangsmåte vedfremstilling derav og farmasöytisk sammensetning inneholdendeforbindelsen, samt anvendelse av denne NO312964B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP07212495		1995-07-28
PCT/JP1996/002053 WO1997005129A1 (en)	1995-07-28	1996-07-23	(r)-5-bromo-n-(1-ethyl-4-methylhexahydro-1h-1,4-diazepin-6-yl)-2-methoxy-6-methylamino-3-pyridine-carboxamide, process for producing the same and medicinal composition containing the same

Publications (3)

Publication Number	Publication Date
NO980333D0 true NO980333D0 (no)	1998-01-26
NO980333L NO980333L (no)	1998-03-23
NO312964B1 NO312964B1 (no)	2002-07-22

Family

ID=16623612

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19980333A NO312964B1 (no)	1995-07-28	1998-01-26	(R)-5-brom-N-(1-etyl-4-metylheksahydro-1H-1,4-diazepin-6-yl)- 2-metoksy-6-metylamino-3-pyridinkarboksamid, fremgangsmåte vedfremstilling derav og farmasöytisk sammensetning inneholdendeforbindelsen, samt anvendelse av denne

Country Status (24)

Country	Link
US (1)	US5945415A (no)
EP (1)	EP0855397B1 (no)
KR (1)	KR19990028395A (no)
CN (1)	CN1096459C (no)
AT (1)	ATE201021T1 (no)
AU (1)	AU700635B2 (no)
BR (1)	BR9609691A (no)
CA (1)	CA2228056A1 (no)
CZ (1)	CZ290442B6 (no)
DE (1)	DE69612753T2 (no)
DK (1)	DK0855397T3 (no)
ES (1)	ES2156616T3 (no)
GR (1)	GR3036089T3 (no)
HU (1)	HUP9901208A3 (no)
IL (1)	IL122753A (no)
MX (1)	MX9800620A (no)
NO (1)	NO312964B1 (no)
NZ (1)	NZ312799A (no)
PL (1)	PL184073B1 (no)
PT (1)	PT855397E (no)
RU (1)	RU2156248C2 (no)
SK (1)	SK282044B6 (no)
TR (1)	TR199800165T1 (no)
WO (1)	WO1997005129A1 (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19650778C2 (de) *	1996-12-06	2001-01-04	Asta Medica Ag	Verwendung von Dopaminrezeptor-Antagonisten in der palliativen Tumortherapie
AU776053B2 (en) *	2000-03-31	2004-08-26	Astellas Pharma Inc.	Diazepan derivatives or salts thereof
US20040048874A1 (en) *	2001-05-22	2004-03-11	Bardsley Hazel Judith	New therapeutic use of 4-(2-fluorophenyl)-6-methyl-2-(1-piperazinyl)thieno[2,3-D]pyrimidine
GB0216027D0 (en) *	2002-07-10	2002-08-21	Arachnova Therapeutics Ltd	New therapeutic use
ITBO20020198A1 (it) *	2002-04-12	2003-10-13	Univ Bologna	Derivati 2 , 5 bis diammino 1 , 4 benzochenionici utili per il trattamento della malattia di alzheimer , metodo per la loro preparazione ed
BRPI0406749A (pt) *	2003-01-13	2005-12-20	Dynogen Pharmaceuticals Inc	Métodos relacionados ao tratamento de distúrbios fincionais do intestino e composição farmacêutica
AU2004204827B2 (en) *	2003-01-13	2006-06-29	Dynogen Pharmaceuticals, Inc.	Method of treating nausea, vomiting, retching or any combination thereof
JP2006522144A (ja) *	2003-04-04	2006-09-28	ダイノゲンファーマシューティカルズ，インコーポレイテッド	下部尿路障害の治療方法
WO2006105117A2 (en) *	2005-03-28	2006-10-05	Dynogen Pharmaceuticals, Inc.	Method of treating disorders and conditions using peripherally-restricted antagonists and inhibitors
AU2010231439A1 (en)	2009-03-31	2011-10-27	Zeria Pharmaceutical Co., Ltd.	Method for manufacturing 1,5-benzodiazepine derivative
EP2818463A1 (en)	2010-08-26	2014-12-31	Kowa Co., Ltd.	Production method of 1,4-diazepane derivatives
RU2438669C1 (ru) *	2010-10-29	2012-01-10	Федеральное государственное автономное образовательное учреждение высшего профессионального образования "ЮЖНЫЙ ФЕДЕРАЛЬНЫЙ УНИВЕРСИТЕТ"	Средство, проявляющее свойства антагониста серотониновых 5-ht3-рецепторов
WO2015114608A1 (en) *	2014-02-03	2015-08-06	Mylan Laboratories Ltd	Processes for the preparation of intermediates of raltegravir

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ230068A (en) *	1988-07-29	1991-07-26	Dainippon Pharmaceutical Co	Indazole-3-carboxylic acid esters and amides of diaza compounds having 6,7, or 8 ring members: preparatory processes and pharmaceutical compositions
US5166341A (en) *	1988-07-29	1992-11-24	Dainippon Pharmaceutical Co., Ltd.	6-amino-1,4-hexahydro-1H-diazepine derivatives
JPH03223265A (ja) *	1990-01-26	1991-10-02	Dainippon Pharmaceut Co Ltd	環状ジアミン誘導体
JPH04210970A (ja) *	1990-01-26	1992-08-03	Dainippon Pharmaceut Co Ltd	ベンズアミド誘導体及びその中間体
SU1825501A3 (ru) *	1990-10-29	1995-12-10	И.В. Комиссаров	Dl-3-[(4-[4- (2-пиридил)-1- пиперазинил]бутил)] -1,8,8-триметил -3-азабицикло[3,2,1] октан-2,4-диона дигидрохлорид, проявляющий противотревожную, нейролептическую и противорвотную активность
PT100990A (pt) *	1991-10-24	1994-01-31	Smithkline Beecham Plc	Derivados de piridina e sua utilizacao como substancia terapeutica

1996
- 1996-07-23 HU HU9901208A patent/HUP9901208A3/hu unknown
- 1996-07-23 ES ES96924189T patent/ES2156616T3/es not_active Expired - Lifetime
- 1996-07-23 NZ NZ312799A patent/NZ312799A/en unknown
- 1996-07-23 BR BR9609691A patent/BR9609691A/pt not_active Application Discontinuation
- 1996-07-23 EP EP96924189A patent/EP0855397B1/en not_active Expired - Lifetime
- 1996-07-23 RU RU98103388/04A patent/RU2156248C2/ru not_active IP Right Cessation
- 1996-07-23 KR KR1019970709711A patent/KR19990028395A/ko not_active Ceased
- 1996-07-23 AT AT96924189T patent/ATE201021T1/de not_active IP Right Cessation
- 1996-07-23 DK DK96924189T patent/DK0855397T3/da active
- 1996-07-23 WO PCT/JP1996/002053 patent/WO1997005129A1/ja not_active Ceased
- 1996-07-23 PT PT96924189T patent/PT855397E/pt unknown
- 1996-07-23 DE DE69612753T patent/DE69612753T2/de not_active Expired - Fee Related
- 1996-07-23 CA CA002228056A patent/CA2228056A1/en not_active Abandoned
- 1996-07-23 AU AU64717/96A patent/AU700635B2/en not_active Ceased
- 1996-07-23 CZ CZ1998230A patent/CZ290442B6/cs not_active IP Right Cessation
- 1996-07-23 MX MX9800620A patent/MX9800620A/es not_active IP Right Cessation
- 1996-07-23 IL IL12275396A patent/IL122753A/xx not_active IP Right Cessation
- 1996-07-23 PL PL96324749A patent/PL184073B1/pl unknown
- 1996-07-23 CN CN96195988A patent/CN1096459C/zh not_active Expired - Fee Related
- 1996-07-23 US US09/000,468 patent/US5945415A/en not_active Expired - Fee Related
- 1996-07-23 SK SK93-98A patent/SK282044B6/sk unknown
- 1996-07-23 TR TR1998/00165T patent/TR199800165T1/xx unknown
1998
- 1998-01-26 NO NO19980333A patent/NO312964B1/no not_active IP Right Cessation
2001
- 2001-06-19 GR GR20010400934T patent/GR3036089T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
PL324749A1 (en)	1998-06-08
NZ312799A (en)	1999-04-29
CA2228056A1 (en)	1997-02-13
CN1096459C (zh)	2002-12-18
MX9800620A (es)	1998-04-30
BR9609691A (pt)	1999-03-23
PL184073B1 (pl)	2002-08-30
HUP9901208A2 (hu)	2000-04-28
HK1018049A1 (en)	1999-12-10
NO312964B1 (no)	2002-07-22
SK282044B6 (sk)	2001-10-08
WO1997005129A1 (en)	1997-02-13
AU6471796A (en)	1997-02-26
US5945415A (en)	1999-08-31
SK9398A3 (en)	1998-08-05
IL122753A0 (en)	1998-08-16
CZ23098A3 (cs)	1998-06-17
KR19990028395A (ko)	1999-04-15
DE69612753D1 (de)	2001-06-13
EP0855397A1 (en)	1998-07-29
TR199800165T1 (xx)	1998-06-22
GR3036089T3 (en)	2001-09-28
HUP9901208A3 (en)	2002-10-28
ATE201021T1 (de)	2001-05-15
DE69612753T2 (de)	2005-07-07
ES2156616T3 (es)	2001-07-01
CN1192213A (zh)	1998-09-02
PT855397E (pt)	2001-08-30
DK0855397T3 (da)	2001-06-25
NO980333L (no)	1998-03-23
EP0855397B1 (en)	2001-05-09
CZ290442B6 (cs)	2002-07-17
IL122753A (en)	2000-10-31
AU700635B2 (en)	1999-01-07
EP0855397A4 (en)	1998-12-02
RU2156248C2 (ru)	2000-09-20

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SE9903544D0 (sv)	1999-10-01	Novel compounds
NO20085078L (no)	2004-06-04	Nye forbindelser
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NO980333D0 (no)	1998-01-26	(R)-5-brom-N-(1-etyl-4-metylheksahydro-1H-1,4-diazepin-6-yl)-2-metoksy-6-metylamino-3-pyridinkarboksamid, fremgangsmåte ved fremstilling derav og farmasöytisk sammensetning inneholdende forbindelsen
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Legal Events

Date	Code	Title	Description
2005-05-02	MM1K	Lapsed by not paying the annual fees