[go: up one dir, main page]

NO984852D0 - Nye benzazepinderivater, medikamenter inneholdende forbindelsene samt deres anvendelse ved fremstilling av medikamentene - Google Patents

Nye benzazepinderivater, medikamenter inneholdende forbindelsene samt deres anvendelse ved fremstilling av medikamentene

Info

Publication number
NO984852D0
NO984852D0 NO984852A NO984852A NO984852D0 NO 984852 D0 NO984852 D0 NO 984852D0 NO 984852 A NO984852 A NO 984852A NO 984852 A NO984852 A NO 984852A NO 984852 D0 NO984852 D0 NO 984852D0
Authority
NO
Norway
Prior art keywords
drugs
compounds
manufacture
benzazepine derivatives
new benzazepine
Prior art date
Application number
NO984852A
Other languages
English (en)
Other versions
NO324211B1 (no
NO984852L (no
Inventor
Laszlo Czollner
Lich Johannes Fr
Ulrich Jordis
Enburg Bernhard K
Original Assignee
Sanochemia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanochemia Ltd filed Critical Sanochemia Ltd
Publication of NO984852D0 publication Critical patent/NO984852D0/no
Publication of NO984852L publication Critical patent/NO984852L/no
Publication of NO324211B1 publication Critical patent/NO324211B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08Bridged systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO19984852A 1996-04-19 1998-10-16 Nye benzazepinderivater, farmasoytisk middel inneholdende forbindelsene samt deres anvendelse ved fremstilling av medikamenter NO324211B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0071696A AT403803B (de) 1996-04-19 1996-04-19 Neue benzazepinderivate, diese enthaltende arzneimittel und verwendung derselben zum herstellen von arzneimitteln
PCT/AT1997/000074 WO1997040049A1 (de) 1996-04-19 1997-04-21 Neue benzazepinderivate, diese enthaltende arzneimittel und verwendung derselben zum herstellen von arzneimitteln

Publications (3)

Publication Number Publication Date
NO984852D0 true NO984852D0 (no) 1998-10-16
NO984852L NO984852L (no) 1998-11-16
NO324211B1 NO324211B1 (no) 2007-09-10

Family

ID=3497932

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19984852A NO324211B1 (no) 1996-04-19 1998-10-16 Nye benzazepinderivater, farmasoytisk middel inneholdende forbindelsene samt deres anvendelse ved fremstilling av medikamenter

Country Status (12)

Country Link
US (2) US6638925B2 (no)
EP (2) EP1757608A1 (no)
AT (1) AT403803B (no)
AU (1) AU2498597A (no)
BG (1) BG64560B1 (no)
CZ (1) CZ300211B6 (no)
IS (1) IS4839A (no)
NO (1) NO324211B1 (no)
PL (2) PL190032B1 (no)
RO (1) RO120136B1 (no)
TW (1) TWI224595B (no)
WO (1) WO1997040049A1 (no)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT403803B (de) * 1996-04-19 1998-05-25 Sanochemia Ltd Neue benzazepinderivate, diese enthaltende arzneimittel und verwendung derselben zum herstellen von arzneimitteln
US7214686B2 (en) 1997-06-30 2007-05-08 Targacept, Inc. Pharmaceutical compositions and methods for effecting dopamine release
AU1430099A (en) * 1998-12-01 2000-06-19 Sanochemia Pharmazeutika Aktiengesellschaft Use of galanthamine and galanthamine derivatives in the case of acute functionalbrain damage
AU774867B2 (en) 1999-05-04 2004-07-08 Neurosearch A/S Heteroaryl diazabicycloalkanes, their preparation and use
KR100768245B1 (ko) * 2000-03-31 2007-10-17 자노케미아 파마조이티카 악티엔게젤샤프트 신규한 갈란타민 유도체 및 유사체
CN1380883A (zh) * 2000-03-31 2002-11-20 萨诺化学药物股份公司 雪花胺的新衍生物和类似物
JP2003534344A (ja) * 2000-05-25 2003-11-18 ターガセプト,インコーポレイテッド ニコチン性コリン受容体リガンドとしてのヘテロアリールジアザビシクロアルカン
US6440970B1 (en) * 2000-05-25 2002-08-27 Targacept, Inc. Pharmaceutical compositions and methods for use
WO2002002564A1 (en) * 2000-07-04 2002-01-10 Neurosearch A/S Aryl and heteroaryl diazabicycloalkanes, their preparation and use
IL154912A0 (en) * 2000-10-19 2003-10-31 Pfizer Prod Inc Bridged piperazine derivatives
EP1340499A4 (en) * 2000-12-07 2006-05-03 Astellas Pharma Inc MEANS FOR REINFORCING THE NOOTROPIC EFFECT
EP1389189A2 (en) * 2001-05-22 2004-02-18 Neurogen Corporation Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues
DE10129265A1 (de) * 2001-06-18 2003-01-02 Hf Arzneimittelforsch Gmbh Wirkstoff-Kombination zur medikamentösen Sucht- oder Rauschmitteltherapie
JP4721386B2 (ja) * 2001-07-10 2011-07-13 第一三共株式会社 新規ガランタミン類縁体
DE10134038A1 (de) * 2001-07-12 2003-02-06 Hf Arzneimittelforsch Gmbh Wirkstoff-Kombination zur medikamentösen Therapie der Nikotinabhängigkeit
DE60330456D1 (de) 2002-07-05 2010-01-21 Targacept Inc N-aryl diazaspirozyklische verbindungen, deren verwendung und das verfahren zu ihren herstellung
AU2003254016A1 (en) 2002-07-19 2004-02-09 Catholic Healthcare West Methods and compositions relating to chimeric nicotinic receptor subunits
US7098331B2 (en) * 2003-03-05 2006-08-29 Targacept, Inc. Arylvinylazacycloalkane compounds and methods of preparation and use thereof
JPWO2005027968A1 (ja) * 2003-09-19 2007-11-15 エーザイ・アール・アンド・ディー・マネジメント株式会社 ダウン症候群治療剤
AT414125B (de) * 2003-09-29 2006-09-15 Sanochemia Pharmazeutika Ag Neue derivate des 4a,5,9,10,11,12-hexahydro- benzofuro(3a,3,2)(2) benzazepin, verfahren zu deren herstellung sowie deren verwendung zur herstellung von arzneimitteln
ES2356356T3 (es) * 2003-10-15 2011-04-07 Targacept, Inc. Compuestos azabicíclicos para aliviar el dolor y tratar los trastornos del sistema nervioso central.
AT500143A1 (de) * 2004-04-22 2005-11-15 Sanochemia Pharmazeutika Ag Cholinesterase-inhibitoren in liposomen sowie deren herstellung und verwendung
US20070004679A1 (en) * 2004-05-17 2007-01-04 Nathalie Schlienger Androgen receptor modulators and methods of treating disease using the same
EP1756101A2 (en) * 2004-05-17 2007-02-28 Acadia Pharmaceuticals Inc. Androgen receptor modulators and method of treating disease using the same
US20050261278A1 (en) 2004-05-21 2005-11-24 Weiner David M Selective serotonin receptor inverse agonists as therapeutics for disease
CN101044134A (zh) * 2004-09-20 2007-09-26 塔加西普特公司 具有烟碱性胆碱能受体活性的氮杂螺烯和氮杂螺烷化合物
KR20070105967A (ko) 2004-11-03 2007-10-31 아이리스 몰레큘라 다이아그노스틱스, 인코오포레이티드 균질 분석물 탐지
US8835186B2 (en) 2004-11-03 2014-09-16 Iris International, Inc. Microbubbles for affinity separation
US7459469B2 (en) * 2004-11-10 2008-12-02 Targacept, Inc. Hydroxybenzoate salts of metanicotine compounds
UA88792C2 (ru) * 2004-11-10 2009-11-25 Таргасепт, Інк. Гидроксибензоатные соли метаникотиновых соединений
ITMI20042413A1 (it) * 2004-12-17 2005-03-17 Indena Spa Processo per la preparazione di galantamina bromidrato
WO2006072818A2 (en) * 2005-01-04 2006-07-13 Emcure Pharmaceuticals Limited Process for preparation of galanthamine
US20060173037A1 (en) * 2005-01-10 2006-08-03 Nathalie Schlienger Aminophenyl derivatives as selective androgen receptor modulators
MX2007008334A (es) * 2005-01-10 2007-09-11 Acadia Pharm Inc Derivados aminofenilo como moduladores de receptor de androgeno selectivos.
US20100168081A1 (en) * 2005-08-11 2010-07-01 Adriana Di Polo Galantamine as a neuroprotective drug for retinal ganglion cells
ATE482959T1 (de) * 2005-08-22 2010-10-15 Targacept Inc Heteroarylsubstituierte diazatricycloalkane, verfahren zu deren herstellung und deren anwendung
US20090253654A1 (en) 2005-09-22 2009-10-08 Galantos Pharma Gmbh Cholinergic enhancers with improved blood-brain barrier permeability for the treatment of diseases accompanied by cognitive impairment
US20070213318A1 (en) * 2006-03-07 2007-09-13 Galantos Pharma Gmbh Cholinergic enhancers with improved blood-brain barrier permeability for the treatment of diseases accompanied by cognitive impairment
EP1777222A1 (en) * 2005-09-22 2007-04-25 Galantos Pharma GmbH Cholinergic enhancers with improved blood-brain barrier permeability for the treatment of diseases accompanied by cognitive impairment
EP1968962A2 (en) 2005-12-14 2008-09-17 Amgen Inc. Diaza heterocyclic sulfonamide derivatives and their uses
US8672732B2 (en) * 2006-01-19 2014-03-18 Schneider Electric It Corporation Cooling system and method
CN100384850C (zh) * 2006-04-14 2008-04-30 浙江大学 加兰他敏衍生物及制备方法和用途
EP2021325A2 (en) * 2006-05-09 2009-02-11 AstraZeneca AB Salt forms of (2s)-(4e)-n-methyl-5-[3-(5-isopropoxypyridin)yl]-4-penten-2-amine
TWI389889B (zh) * 2006-05-09 2013-03-21 Targacept Inc (2s)-(4e)-n-甲基-5-〔3-(5-異丙氧基吡啶)基〕-4-戊烯-2-胺之新穎多晶型
JP5179486B2 (ja) 2006-06-28 2013-04-10 アムジエン・インコーポレーテツド グリシン輸送体−1阻害剤
AR062860A1 (es) * 2006-09-15 2008-12-10 Astrazeneca Ab Combinaciones terapeuticas 482
US20100028447A1 (en) * 2007-01-22 2010-02-04 Targacept, Inc. Intranasal, Buccal, And Sublingual Administration Of Metanicotine Analogs
AU2008282205A1 (en) * 2007-07-31 2009-02-05 Astrazeneca Ab Transdermal administration of (2S)-(4E)-N-methyl-5-(3-( 5-isopropoxypyridin)yl)-4-penten-2-amine
DK2217597T3 (da) 2007-10-01 2011-06-20 Comentis Inc Quinuclidin-4-ylmethyl-1h-indol-3-carboxylatderivater som alpha-7-nicotin-acetylcholin-receptor-ligander til behandling af Alzheimers sygdom
CA2721007C (en) 2008-04-14 2014-04-29 Galantos Pharma Gmbh Derivatives of galantamine as pro-drugs for the treatment of human brain diseases
AU2010328419A1 (en) 2009-12-07 2012-06-21 Targacept, Inc. 3,6-diazabicyclo[3.1.1]heptanes as neuronal nicotinic acetylcholine receptor ligands
EP2574188A4 (en) 2010-05-20 2015-09-02 Targacept Inc NOVEL PROCESS FOR THE PREPARATION OF ARYL SUBSTITUTED OLEFIN AMINES
WO2013160728A1 (en) 2012-04-26 2013-10-31 Alma Mater Studiorum - Universita' Di Bologna Dual targeting compounds for the treatment of alzheimer's disease
CN104447767B (zh) * 2013-09-24 2018-08-03 连云港金康医药科技有限公司 氮杂双环[3,2,1]辛烷衍生物及其应用
AR101131A1 (es) 2014-07-11 2016-11-23 Comentis Inc QUINUCLIDINAS PARA LA MODULACIÓN DE ACTIVIDAD DE a7
WO2017189834A1 (en) * 2016-04-29 2017-11-02 New Mexico Tech Research Foundation Methods for treatment of resistant cancer
CN118908968B (zh) * 2024-10-09 2025-03-04 威胜生物医药(苏州)股份有限公司 一种加兰他敏中间体衍生物及其催化氧化制备方法

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3947445A (en) 1974-05-09 1976-03-30 Stanford Research Institute Diazabicyclooctanes and diazabicycloheptanes
US4663318A (en) * 1986-01-15 1987-05-05 Bonnie Davis Method of treating Alzheimer's disease
EP0363415B1 (en) * 1987-05-04 2008-10-15 Davis, Bonnie Compounds for the treatment of alzheimer's disease
GB8800694D0 (en) 1988-01-13 1988-02-10 Pfizer Ltd Antiarrhythmic agents
NL8800350A (nl) * 1988-02-12 1989-09-01 Stichting Biomedical Research Synthetische galanthamine-derivaten, werkwijze voor het bereiden daarvan, en farmaceutische samenstellingen.
US4954502A (en) 1988-06-10 1990-09-04 Bristol-Myers Squibb Company 1-indolyalkyl-4-(substituted-pyridinyl)piperazines
CA2012681A1 (en) 1989-03-31 1990-09-30 Masayasu Okuhira Quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same
US5036153A (en) 1989-05-11 1991-07-30 Braish Tamim F Preparation of 2,5-diazabicyclo[2.2.1]heptanes and intermediates
US4994460A (en) 1989-06-01 1991-02-19 Bristol-Myers Squibb Co. Agents for treatment of brain ischemia
WO1991009849A1 (en) 1989-12-28 1991-07-11 The Upjohn Company Diaromatic substituted anti-aids compounds
US5336675A (en) * 1991-05-14 1994-08-09 Ernir Snorrason Method of treating mania in humans
HU213097B (en) 1991-05-14 1997-02-28 Egyt Gyogyszervegyeszeti Gyar Process for producing phenylpiperazines
US5153193A (en) * 1991-10-01 1992-10-06 Hoechst-Roussel Pharmaceuticals Incorporated Carbamate derivatives of 4-amino-3-isoxazolidinones, 3-amino-1-hydroxypyrrolidin-2-ones and 1-amino-1-cyclopropanecarboxylic acid analogs
SK283420B6 (sk) 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
US6316439B1 (en) 1993-10-15 2001-11-13 Aventis Pharamaceuticals Inc. Galanthamine derivatives as acetylcholinesterase inhibitors
US6323195B1 (en) * 1993-10-15 2001-11-27 Aventis Pharmaceuticals Inc. Galanthamine derivatives as acetylcholinesterase inhibitors
US6323196B1 (en) 1993-10-15 2001-11-27 Aventis Pharmaceuticals Inc. Galanthamine derivatives as acetylcholinesterase inhibitors
US5428159A (en) 1994-04-08 1995-06-27 Ciba-Geigy Corporation Method of manufacture of (-)-galanthamine in high yield and purity substantially free of epigalanthamine
SI0787115T1 (en) * 1994-10-21 2000-04-30 Sanochemia Pharmazeutika Ag PROCESS FOR PRODUCING DERIVATIVES OF 4a,5,9,10,11,12,-HEXAHYDRO-6H-BENZOFURO(3a,3,2-ef)(2)BENZAZEPINE
AT401058B (de) 1994-10-21 1996-06-25 Waldheim Pharmazeutika Gmbh Verfahren zum herstellen von derivaten des 4a,5, 9,10,11,12,-hexahydro-6h-benzofuro(3a,-3,2-ef) (2)benzazepins
US6407229B1 (en) * 1994-10-21 2002-06-18 Sanochemia Pharmazeutika Ag Processes for the preparation of derivatives of 4a,5,9,10,11,12-hexahydro-6H-benzofuro-[3a,3,2-ef][2] benzazapine
GB9519268D0 (en) 1995-09-21 1995-11-22 Chiroscience Ltd Preparation of alkaloids
AT403803B (de) * 1996-04-19 1998-05-25 Sanochemia Ltd Neue benzazepinderivate, diese enthaltende arzneimittel und verwendung derselben zum herstellen von arzneimitteln
AU1430099A (en) 1998-12-01 2000-06-19 Sanochemia Pharmazeutika Aktiengesellschaft Use of galanthamine and galanthamine derivatives in the case of acute functionalbrain damage
AT414125B (de) 2003-09-29 2006-09-15 Sanochemia Pharmazeutika Ag Neue derivate des 4a,5,9,10,11,12-hexahydro- benzofuro(3a,3,2)(2) benzazepin, verfahren zu deren herstellung sowie deren verwendung zur herstellung von arzneimitteln

Also Published As

Publication number Publication date
NO324211B1 (no) 2007-09-10
IS4839A (is) 1998-08-28
US20040067974A1 (en) 2004-04-08
PL329411A1 (en) 1999-03-29
AT403803B (de) 1998-05-25
PL190032B1 (pl) 2005-10-31
US6638925B2 (en) 2003-10-28
EP0897387A1 (de) 1999-02-24
BG102836A (en) 1999-09-30
CZ332498A3 (cs) 1999-05-12
EP1757608A1 (de) 2007-02-28
BG64560B1 (bg) 2005-07-29
ATA71696A (de) 1997-10-15
PL189834B1 (pl) 2005-09-30
WO1997040049A1 (de) 1997-10-30
US20030092700A1 (en) 2003-05-15
AU2498597A (en) 1997-11-12
CZ300211B6 (cs) 2009-03-18
US7101890B2 (en) 2006-09-05
RO120136B1 (ro) 2005-09-30
TWI224595B (en) 2004-12-01
NO984852L (no) 1998-11-16

Similar Documents

Publication Publication Date Title
NO984852L (no) Nye benzazepinderivater, medikamenter inneholdende forbindelsene samt deres anvendelse ved fremstilling av medikamentene
NO307091B1 (no) Nye pyrido[3,2-e]pyrazinoner, legemiddel inneholdende samme, samt anvendelse av samme for fremstilling av legemiddel
NO304488B1 (no) 5-leddede heteroaryloksazolidinoner, anvendelse av disse for fremstilling av legemidler samt legemiddel inneholdende forbindelsen
EE9700031A (et) Pürido-liitunud tienüül- ja furanüüloksasolidinoonid, nende valmistamismeetod, kasutamine ravimite valmistamiseks ja nimetatud ühendeid sisaldavad ravimid
NO982580L (no) Nye taxoider, deres fremstilling samt farmas°ystiske preparater inneholdende taxoidene
NO20025004L (no) Fremgangsmåte for fremstilling av 2,5-diketopiperaziner, 2,5- diketopiperaziner, dipeptider samt anvendelse derav
NO990793D0 (no) 7<alfa>-(<Epsilon>-aminoalkyl)-°stratriener, fremgangsmÕte for fremstilling av disse, farmas°ytiske preparater inneholdende disse, samt deres anvendelse for fremstilling av legemidler
NO20021714D0 (no) 2-fenyl-substituerte imidazotriazinoner, fremgangsmåte for fremstilling derav samt anvendelse av forbindelsene
FI964249A7 (fi) Muovipäällysteinen, amoksisilliinia ja klavulanaattia käsittävä tablet ti
EE9700044A (et) Heteroarüüloksasolidinoonid, nende valmistamismeetod, kasutamine ravimite valmistamiseks ja nimetatud ühendeid sisaldavad ravimid.
FI955091A7 (fi) Parannetut farmaseuttisesti hyväksyttävät seokset, jotka sisältävät al koholia ja hydrofobista lääkettä
NO900613D0 (no) Fremgangsmaate for fremstilling av aktiverte chitosaner oganvendelse ved fremstilling av chitosanderivater.
EE9700019A (et) 2-okso- ja 2-tio1,2-dihüdrokinolinüüloksasolidinoonid, nende valmistamismeetod, kasutamine ravimite valmistamiseks ja nimetatud ühendeid sisaldavad ravimid
DE59905572D1 (de) Substituierte 4-amino-2-aryl-pyrimidine, ihre herstellung, ihre verwendung und sie enthaltende pharmazeutische präparate
NO974375D0 (no) Stötfanger, samt tilvirkning av samme
NO952493D0 (no) Pyrrolidin- og tiazolidinderivater, deres fremstilling samt medikamenter inneholdende forbindelsene
NO308287B1 (no) Substituerte 4-fenyl-6-amino-nikotinsyrederivater, legemidler inneholdende disse samt deres anvendelse
NO942910L (no) Nye baccatin-III- og 10-desacetyl-baccatin-III-derivater, deres fremstillinger, samt farmasöytiske preparater inneholdende derivatene
NO995723L (no) Nye triptolidderivater som er anvendbare ved behandling av autoimmune sykdommer
NO306060B1 (no) Substituerte kanelsyreguanidider, deres anvendelse samt medikamenter inneholdende guanididene
NO308251B1 (no) Karbohydratderivater, farmasøytisk blanding inneholdende karbohydratderivater samt anvendelse av samme
NO995722D0 (no) Nye triptolidderivater som er anvendbare ved behandling av autoimmune sykdommer
IL127518A0 (en) Substituted heterocyclic benzocycloalkenes and the use thereof as substances having an analgesic effect
NO996438D0 (no) Ny kombinasjon av astmamedikamenter
NO308528B1 (no) Substituerte 1-naftoylguanidiner, deres anvendelse for fremstilling av medikamenter samt helbredende middel inneholdende forbindelsene

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees