NO984418L - Arylaminokondenserte pyridiner og pyrimidiner - Google Patents
Arylaminokondenserte pyridiner og pyrimidinerInfo
- Publication number
- NO984418L NO984418L NO984418A NO984418A NO984418L NO 984418 L NO984418 L NO 984418L NO 984418 A NO984418 A NO 984418A NO 984418 A NO984418 A NO 984418A NO 984418 L NO984418 L NO 984418L
- Authority
- NO
- Norway
- Prior art keywords
- arylamino
- pyrimidines
- condensed pyridines
- pyridines
- condensed
- Prior art date
Links
- 125000001769 aryl amino group Chemical group 0.000 title 1
- 150000003222 pyridines Chemical class 0.000 title 1
- 150000003230 pyrimidines Chemical class 0.000 title 1
- 102000012289 Corticotropin-Releasing Hormone Human genes 0.000 abstract 2
- 108010022152 Corticotropin-Releasing Hormone Proteins 0.000 abstract 2
- 239000000055 Corticotropin-Releasing Hormone Substances 0.000 abstract 2
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000926 neurological effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Luminescent Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1415796P | 1996-03-27 | 1996-03-27 | |
| US64661296A | 1996-05-08 | 1996-05-08 | |
| US3053696P | 1996-10-31 | 1996-10-31 | |
| US3912497P | 1997-02-25 | 1997-02-25 | |
| PCT/US1997/004852 WO1997035539A2 (fr) | 1996-03-27 | 1997-03-25 | Pyridines et pyrimidines a fusion arylamino |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO984418D0 NO984418D0 (no) | 1998-09-22 |
| NO984418L true NO984418L (no) | 1998-11-03 |
Family
ID=27486365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO984418A NO984418L (no) | 1996-03-27 | 1998-09-22 | Arylaminokondenserte pyridiner og pyrimidiner |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US6107300A (fr) |
| EP (1) | EP0935601A4 (fr) |
| JP (1) | JP2002515032A (fr) |
| KR (1) | KR20000005037A (fr) |
| CN (1) | CN1230184A (fr) |
| AU (1) | AU2545897A (fr) |
| BR (1) | BR9708261A (fr) |
| CA (1) | CA2250241A1 (fr) |
| CZ (1) | CZ304098A3 (fr) |
| EA (1) | EA199800868A1 (fr) |
| EE (1) | EE9800329A (fr) |
| HR (1) | HRP970173A2 (fr) |
| HU (1) | HUP9902340A3 (fr) |
| IL (1) | IL126316A0 (fr) |
| LV (1) | LV12262B (fr) |
| NO (1) | NO984418L (fr) |
| NZ (1) | NZ331874A (fr) |
| PL (1) | PL335258A1 (fr) |
| SI (1) | SI9720026A (fr) |
| SK (1) | SK131798A3 (fr) |
| WO (1) | WO1997035539A2 (fr) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1066147C (zh) | 1995-11-01 | 2001-05-23 | 诺瓦提斯公司 | 嘌呤衍生物及其制备方法 |
| CN1251100A (zh) * | 1997-03-21 | 2000-04-19 | 杜邦药品公司 | 芳氨基三唑并吡啶的制备方法 |
| AU8181098A (en) * | 1997-07-03 | 1999-01-25 | Du Pont Pharmaceuticals Company | Aryl-and arylamino-substituted heterocycles as corticotropin releasing hormone antagonists |
| US6156898A (en) * | 1998-02-26 | 2000-12-05 | Neurogen Corporation | Substituted 1,4-dihydro-4-oxonicotinic carboxamides; GABA brain receptor ligands |
| WO2000027846A2 (fr) | 1998-11-12 | 2000-05-18 | Neurocrine Biosciences, Inc. | Antagonistes de recepteurs du crf et methodes associees |
| JP2002529469A (ja) | 1998-11-12 | 2002-09-10 | ニューロクライン バイオサイエンシーズ, インコーポレイテッド | Crfレセプターアンタゴニストおよびそれに関する方法 |
| US6531475B1 (en) | 1998-11-12 | 2003-03-11 | Neurocrine Biosciences, Inc. | CRF receptor antagonists and methods relating thereto |
| GB9903762D0 (en) | 1999-02-18 | 1999-04-14 | Novartis Ag | Organic compounds |
| AU7738000A (en) | 1999-09-30 | 2001-04-30 | Neurogen Corporation | Certain alkylene diamine-substituted heterocycles |
| WO2001044257A1 (fr) * | 1999-12-17 | 2001-06-21 | Ariad Pharmaceuticals, Inc. | Inhibiteurs de la pompe a protons |
| US7115589B2 (en) * | 1999-12-17 | 2006-10-03 | Ariad Pharmaceuticals, Inc. | Purine derivatives |
| AU2001232271A1 (en) * | 2000-02-14 | 2001-08-20 | Japan Tobacco Inc. | Preventives/remedies for postoperative stress |
| JP2004532792A (ja) | 2000-07-14 | 2004-10-28 | ブリストル−マイヤーズ・スクイブ・ファーマ・カンパニー | 神経障害を治療するためのイミダゾ[1,2−a]ピラジン |
| YU63703A (sh) | 2001-02-12 | 2006-05-25 | F. Hoffmann-La Roche Ag. | 6-supstituisani pirido-pirimidini |
| DE60218434T2 (de) | 2001-03-13 | 2007-11-08 | Bristol-Myers Squibb Pharma Co. | 4-(2-BUTYLAMINO)-2,7-DIMETHYL-8-(2-METHYL-6-METHOXYPYRID-3-YL) PYRAZOLO- 1,5-Aö-1,3,5-TRIAZIN, SEINE ENANTIOMEREN UND PHARMAZEUTISCH ANNEHMBARE SALZE ALS CORTICOTROPIN-RELEASING-FACTOR-REZEPTOR-LIGANDEN |
| DE60217669D1 (de) | 2001-05-14 | 2007-03-08 | Bristol Myers Squibb Co | Substitutierte pyrazinone, pyridine und pyrimidine als corticotropin-releasing-factor liganden |
| PE20030008A1 (es) | 2001-06-19 | 2003-01-22 | Bristol Myers Squibb Co | Inhibidores duales de pde 7 y pde 4 |
| WO2003005969A2 (fr) | 2001-07-12 | 2003-01-23 | Bristol-Myers Squibb Pharma Company | Tetrahydropurinones et leurs derives en tant que ligands du recepteur du facteur de liberation de corticotropine |
| WO2003006015A1 (fr) | 2001-07-13 | 2003-01-23 | Bristol-Myers Squibb Pharma Company | Thiazoles et oxazoles substitutes utilises comme ligands hormonaux de liberation de la corticotrophine |
| GB0117522D0 (en) | 2001-07-19 | 2001-09-12 | Procter & Gamble | Solvent welding process |
| GB0117525D0 (en) | 2001-07-19 | 2001-09-12 | Procter & Gamble | Solvent welding process |
| US20030119831A1 (en) | 2001-11-20 | 2003-06-26 | Hartz Richard A. | 3,7-dihydro-purine-2,6-dione derivatives as CRF receptor ligands |
| US9967633B1 (en) | 2001-12-14 | 2018-05-08 | At&T Intellectual Property I, L.P. | System and method for utilizing television viewing patterns |
| AU2002359732A1 (en) * | 2001-12-17 | 2003-06-30 | Ribapharm Inc. | Substituted purine nucleoside libraries and compounds by solid-phase combinatorial strategies |
| GB0219746D0 (en) | 2002-08-23 | 2002-10-02 | Inst Of Ex Botany Ascr | Azapurine derivatives |
| SE0301373D0 (sv) * | 2003-05-09 | 2003-05-09 | Astrazeneca Ab | Novel compounds |
| WO2005009348A2 (fr) * | 2003-06-25 | 2005-02-03 | Ariad Pharmaceuticals, Inc. | Derives de purine substitues |
| KR20060072142A (ko) * | 2003-09-09 | 2006-06-27 | 오노 야꾸힝 고교 가부시키가이샤 | Crf 길항제 및 이환식 복소환 화합물 |
| ES2651730T3 (es) * | 2003-09-26 | 2018-01-29 | Exelixis, Inc. | Moduladores c-Met y métodos de uso |
| JP2007526339A (ja) * | 2004-03-02 | 2007-09-13 | ニューロジェン・コーポレーション | アリール置換プリン類縁体 |
| EP1598354A1 (fr) * | 2004-05-18 | 2005-11-23 | Vasopharm Biotech GmbH | Composes contenant un groupement n-heteroaryle lie a un cycle condense et leur utilisation comme inhibiteurs du nad(p)h oxidases et de l'activation plaquettaire |
| EP1773826A4 (fr) * | 2004-07-02 | 2009-06-03 | Exelixis Inc | Modulateurs de c-met et leur methode d'utilisation |
| US7572805B2 (en) | 2004-07-14 | 2009-08-11 | Bristol-Myers Squibb Company | Pyrrolo(oxo)isoquinolines as 5HT ligands |
| WO2006010264A1 (fr) * | 2004-07-30 | 2006-02-02 | Methylgene, Inc. | Inhibiteurs de signalisation de recepteur du facteur de croissance endotheliale (vegf) et de recepteur de facteur de croissance des hepatocytes (hgf) |
| ATE421518T1 (de) * | 2005-02-10 | 2009-02-15 | Bristol Myers Squibb Co | Dihydrochinazolinone als 5ht-modulatoren |
| EP1703668A1 (fr) * | 2005-03-18 | 2006-09-20 | Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO | Système pour traiter des paramètres "qualité de service" (qos) dans un réseau de communications |
| EP1957498B1 (fr) * | 2005-05-20 | 2017-02-15 | MethylGene Inc. | Inhibiteurs de la signalisation du récepteur vegf et du récepteur hgf |
| EP1904504B1 (fr) * | 2005-05-20 | 2014-03-19 | MethylGene Inc. | Inhibiteur de la signalisation du recepteur vegf et hgf |
| US7973025B2 (en) | 2005-05-26 | 2011-07-05 | Neuron Systems, Inc. | Compositions and methods of treating retinal disease |
| EA200800430A1 (ru) * | 2005-07-28 | 2008-06-30 | Бристол-Маерс Сквибб Компани | Замещённые тетрагидро-1н-пиридо[4,3,b] индолы как агонисты и антагонисты серотониновых рецепторов |
| US7795436B2 (en) * | 2005-08-24 | 2010-09-14 | Bristol-Myers Squibb Company | Substituted tricyclic heterocycles as serotonin receptor agonists and antagonists |
| BRPI0618636A2 (pt) * | 2005-11-08 | 2011-09-06 | Hoffmann La Roche | derivados de tiazolo [4,5-c]piridina |
| PE20080145A1 (es) * | 2006-03-21 | 2008-02-11 | Janssen Pharmaceutica Nv | Tetrahidro-pirimidoazepinas como moduladores de trpv1 |
| WO2007107005A1 (fr) * | 2006-03-22 | 2007-09-27 | Methylgene, Inc. | Inhibiteurs de l'activité protéine tyrosine kinase |
| EP2044086A2 (fr) * | 2006-06-30 | 2009-04-08 | Janssen Pharmaceutica N.V. | Modulateurs de trpv1 à base de thiazolopyrimidine |
| CA2668182A1 (fr) | 2006-10-31 | 2008-05-08 | Janssen Pharmaceutica N.V. | Derives de triazolopyrimidine convenant comme antagonistes du recepteur p2y12 de l'adp |
| WO2008054795A2 (fr) * | 2006-10-31 | 2008-05-08 | Janssen Pharmaceutica, N.V. | Dérivés de triazolopyrimidine convenant comme antagonistes du récepteur p2y12 de l'adp |
| CA2673654A1 (fr) * | 2007-01-10 | 2008-07-17 | Albany Molecular Research, Inc. | Indazoles 5-pyridinone substituees |
| BRPI0814772A2 (pt) * | 2007-07-21 | 2015-03-03 | Albany Molecular Res Inc | Indazóis substituídos por 5-piridinona |
| WO2009078999A1 (fr) | 2007-12-17 | 2009-06-25 | Janssen Pharmaceutica N.V. | Modulateurs imidazolo-, oxazolo- et thiazolopyrimidines de trpv1 |
| EP2332536A1 (fr) * | 2008-03-05 | 2011-06-15 | MethylGene Inc. | Inhibiteurs d'activité de kinase de tyrosine de protéine |
| US8273900B2 (en) | 2008-08-07 | 2012-09-25 | Novartis Ag | Organic compounds |
| CA2758030C (fr) | 2009-01-16 | 2019-01-08 | Exelixis, Inc. | Sel de malate de n-(4-{[6,7-bis(methyloxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide et formes cristallines de celui-ci pour le traitement du cancer |
| UA108618C2 (uk) | 2009-08-07 | 2015-05-25 | Застосування c-met-модуляторів в комбінації з темозоломідом та/або променевою терапією для лікування раку | |
| CA2782015C (fr) | 2009-12-11 | 2020-08-25 | Neuron Systems, Inc. | Compositions ophthalmiques topiques et methodes de traitement de la degenerescence maculaire |
| EP2919788A4 (fr) | 2012-11-14 | 2016-05-25 | Univ Johns Hopkins | Méthodes et compositions pour le traitement de la schizophrénie |
| HK1217439A1 (zh) | 2013-01-23 | 2017-01-13 | Aldeyra Therapeutics, Inc. | 与毒性醛相关的疾病和治疗 |
| US9868744B2 (en) | 2014-04-25 | 2018-01-16 | Pfizer Inc. | Heteroaromatic compounds and their use as dopamine D1 ligands |
| EP3259274B1 (fr) * | 2015-02-18 | 2023-06-28 | Buck Institute for Research on Aging | Triazolopyridines et triazolopyrimidines qui abaissent la p-tau provoquée par le stress |
| MX2018002155A (es) | 2015-08-21 | 2018-06-08 | Aldeyra Therapeutics Inc | Compuestos deuterados y usos de los mismos. |
| US11370793B2 (en) | 2015-08-27 | 2022-06-28 | Nantneuro, Llc | Triazolopyridines and triazolopyrimidines that lower stress-induced p-tau |
| JP7311162B2 (ja) | 2017-10-10 | 2023-07-19 | アルデイラ セラピューティクス, インコーポレイテッド | 炎症性障害の処置 |
| JP2021527687A (ja) * | 2018-06-21 | 2021-10-14 | ヤンセン ファーマシューティカ エヌ.ベー. | Oga阻害剤化合物 |
| WO2020033344A1 (fr) * | 2018-08-06 | 2020-02-13 | Aldeyra Therapeutics, Inc. | Composés polymorphes et leurs utilisations |
| US12098132B2 (en) | 2019-05-02 | 2024-09-24 | Aldeyra Therapeutics, Inc. | Process for preparation of aldehyde scavenger and intermediates |
| WO2020223685A1 (fr) | 2019-05-02 | 2020-11-05 | Aldeyra Therapeutics, Inc. | Composés polymorphes et leurs utilisations |
| WO2021231792A1 (fr) | 2020-05-13 | 2021-11-18 | Aldeyra Therapeutics, Inc. | Formulations pharmaceutiques et leurs utilisations |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1544419A (en) * | 1975-11-19 | 1979-04-19 | Science Union & Cie | Purines and pyrazolo-pyrimidines a process for their preparation and pharmaceutical compositions containing them |
| US4076711A (en) * | 1976-04-05 | 1978-02-28 | Schering Corporation | Triazolo [4,5-d]-pyrimidines |
| EP0155911A1 (fr) * | 1984-03-19 | 1985-09-25 | Ciba-Geigy Ag | Dérivés de la purine pour la régulation de croissance des plantes |
| GB8408615D0 (en) * | 1984-04-04 | 1984-05-16 | Wellcome Found | Heterocyclic compounds |
| US5310731A (en) * | 1984-06-28 | 1994-05-10 | Whitby Research, Inc. | N-6 substituted-5'-(N-substitutedcarboxamido)adenosines as cardiac vasodilators and antihypertensive agents |
| US5175273A (en) * | 1988-07-01 | 1992-12-29 | Genentech, Inc. | Nucleic acid intercalating agents |
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| CA2100863A1 (fr) * | 1991-01-23 | 1992-07-24 | David A. Bullough | Inhibiteurs de l'adenosine-kinase |
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| BR9206810A (pt) * | 1991-11-25 | 1995-10-31 | Pfizer | Derivados de indol |
| ES2130246T3 (es) * | 1992-01-06 | 1999-07-01 | Wellcome Found | Nucleosidos terapeuticos de la serie 2',3'-didesoxi-3'-fluoro-purina. |
| US5424297A (en) * | 1992-04-27 | 1995-06-13 | University Of Virginia Alumni Patents Foundation | Adenosine dextran conjugates |
| TW370529B (en) * | 1992-12-17 | 1999-09-21 | Pfizer | Pyrazolopyrimidines |
| EP0764153A1 (fr) * | 1994-06-06 | 1997-03-26 | Pfizer Inc. | Pyrazoles substitues ayant une activite antagoniste du facteur liberant la corticotropine (flc) |
| TW530047B (en) * | 1994-06-08 | 2003-05-01 | Pfizer | Corticotropin releasing factor antagonists |
| ATE182332T1 (de) * | 1994-06-16 | 1999-08-15 | Pfizer | Pyrazolo und pyrrolopyridine |
| ATE182148T1 (de) * | 1995-05-12 | 1999-07-15 | Neurogen Corp | Neue deazapurinderivate; eine neue klasse von crf1-spezifischen liganden |
| ES2200039T3 (es) * | 1995-12-08 | 2004-03-01 | Pfizer Inc. | Derivados heterociclicos sustituidos como antagonistas de crf. |
-
1997
- 1997-03-21 US US08/823,029 patent/US6107300A/en not_active Expired - Lifetime
- 1997-03-25 CN CN97194897A patent/CN1230184A/zh active Pending
- 1997-03-25 NZ NZ331874A patent/NZ331874A/xx unknown
- 1997-03-25 CZ CZ983040A patent/CZ304098A3/cs unknown
- 1997-03-25 JP JP53457797A patent/JP2002515032A/ja active Pending
- 1997-03-25 SI SI9720026A patent/SI9720026A/sl not_active IP Right Cessation
- 1997-03-25 EP EP97916991A patent/EP0935601A4/fr not_active Withdrawn
- 1997-03-25 KR KR1019980707661A patent/KR20000005037A/ko not_active Withdrawn
- 1997-03-25 AU AU25458/97A patent/AU2545897A/en not_active Abandoned
- 1997-03-25 BR BR9708261-9A patent/BR9708261A/pt not_active IP Right Cessation
- 1997-03-25 WO PCT/US1997/004852 patent/WO1997035539A2/fr not_active Ceased
- 1997-03-25 EE EE9800329A patent/EE9800329A/xx unknown
- 1997-03-25 IL IL12631697A patent/IL126316A0/xx unknown
- 1997-03-25 HU HU9902340A patent/HUP9902340A3/hu unknown
- 1997-03-25 CA CA002250241A patent/CA2250241A1/fr not_active Abandoned
- 1997-03-25 PL PL97335258A patent/PL335258A1/xx unknown
- 1997-03-25 EA EA199800868A patent/EA199800868A1/ru unknown
- 1997-03-25 SK SK1317-98A patent/SK131798A3/sk unknown
- 1997-03-26 HR HR60/039,124A patent/HRP970173A2/hr not_active Application Discontinuation
-
1998
- 1998-09-22 NO NO984418A patent/NO984418L/no unknown
- 1998-10-30 LV LVP-98-195A patent/LV12262B/en unknown
-
2000
- 2000-03-14 US US09/525,619 patent/US6448261B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2545897A (en) | 1997-10-17 |
| WO1997035539A3 (fr) | 1999-05-14 |
| NZ331874A (en) | 2000-03-27 |
| US6107300A (en) | 2000-08-22 |
| HUP9902340A2 (hu) | 1999-11-29 |
| WO1997035539A2 (fr) | 1997-10-02 |
| HUP9902340A3 (en) | 2001-02-28 |
| CN1230184A (zh) | 1999-09-29 |
| CA2250241A1 (fr) | 1997-10-02 |
| BR9708261A (pt) | 2001-12-04 |
| JP2002515032A (ja) | 2002-05-21 |
| EP0935601A4 (fr) | 2002-08-07 |
| PL335258A1 (en) | 2000-04-10 |
| EP0935601A2 (fr) | 1999-08-18 |
| SK131798A3 (en) | 2000-05-16 |
| LV12262A (lv) | 1999-04-20 |
| EA199800868A1 (ru) | 1999-04-29 |
| EE9800329A (et) | 1999-06-15 |
| CZ304098A3 (cs) | 1999-02-17 |
| NO984418D0 (no) | 1998-09-22 |
| US6448261B1 (en) | 2002-09-10 |
| HRP970173A2 (en) | 1999-08-31 |
| IL126316A0 (en) | 1999-05-09 |
| LV12262B (en) | 1999-10-20 |
| KR20000005037A (ko) | 2000-01-25 |
| SI9720026A (sl) | 1999-04-30 |
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