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NO976064D0 - Somatostatin peptider - Google Patents

Somatostatin peptider

Info

Publication number
NO976064D0
NO976064D0 NO976064A NO976064A NO976064D0 NO 976064 D0 NO976064 D0 NO 976064D0 NO 976064 A NO976064 A NO 976064A NO 976064 A NO976064 A NO 976064A NO 976064 D0 NO976064 D0 NO 976064D0
Authority
NO
Norway
Prior art keywords
residue
ala
amino acid
lys
somatostain
Prior art date
Application number
NO976064A
Other languages
English (en)
Other versions
NO317867B1 (no
NO976064L (no
Inventor
Rainer Albert
Wilfried Bauer
Christian Bruns
Nagarajan Chandramouli
Ian Lewis
Gisbert Weckbecker
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26307298&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO976064(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9513224.7A external-priority patent/GB9513224D0/en
Priority claimed from GBGB9600429.6A external-priority patent/GB9600429D0/en
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO976064D0 publication Critical patent/NO976064D0/no
Publication of NO976064L publication Critical patent/NO976064L/no
Publication of NO317867B1 publication Critical patent/NO317867B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/655Somatostatins
    • C07K14/6555Somatostatins at least 1 amino acid in D-form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/655Somatostatins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/31Somatostatins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/083Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Transplantation (AREA)
  • Emergency Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
NO19976064A 1995-06-29 1997-12-23 Sykliske somatostatin heksapeptider, farmasoytiske sammensetninger omfattende slike, og anvendelse av slike heksapeptider for fremstilling av farmasoytiske sammensetninger. NO317867B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9513224.7A GB9513224D0 (en) 1995-06-29 1995-06-29 Organic compounds
GBGB9600429.6A GB9600429D0 (en) 1996-01-10 1996-01-10 Organic compounds
PCT/EP1996/002840 WO1997001579A2 (en) 1995-06-29 1996-06-28 Somatostatin peptides

Publications (3)

Publication Number Publication Date
NO976064D0 true NO976064D0 (no) 1997-12-23
NO976064L NO976064L (no) 1998-02-16
NO317867B1 NO317867B1 (no) 2004-12-27

Family

ID=26307298

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19976064A NO317867B1 (no) 1995-06-29 1997-12-23 Sykliske somatostatin heksapeptider, farmasoytiske sammensetninger omfattende slike, og anvendelse av slike heksapeptider for fremstilling av farmasoytiske sammensetninger.

Country Status (24)

Country Link
US (1) US6225284B1 (no)
EP (1) EP0835263B9 (no)
JP (2) JP3445796B2 (no)
KR (1) KR100454664B1 (no)
CN (1) CN1156492C (no)
AT (1) ATE210152T1 (no)
AU (1) AU714447B2 (no)
BR (1) BR9609335B8 (no)
CA (1) CA2222524C (no)
CZ (1) CZ297381B6 (no)
DE (1) DE69617687T2 (no)
DK (1) DK0835263T3 (no)
ES (1) ES2169251T3 (no)
HU (1) HU228984B1 (no)
IL (1) IL122243A (no)
MY (1) MY147327A (no)
NO (1) NO317867B1 (no)
NZ (1) NZ313147A (no)
PL (1) PL184947B1 (no)
PT (1) PT835263E (no)
SK (1) SK284087B6 (no)
TR (1) TR199701718T1 (no)
TW (1) TW491854B (no)
WO (1) WO1997001579A2 (no)

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US5968903A (en) * 1998-05-07 1999-10-19 Biomeasure, Incorporated Inhibition of H. pylori proliferation
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US6608027B1 (en) 1999-04-06 2003-08-19 Boehringer Ingelheim (Canada) Ltd Macrocyclic peptides active against the hepatitis C virus
US6358491B1 (en) 1999-08-27 2002-03-19 Berlex Laboratories, Inc. Somatostatin analogs
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GB0018891D0 (en) 2000-08-01 2000-09-20 Novartis Ag Organic compounds
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US7122172B1 (en) 2000-03-08 2006-10-17 Gerhart Graupner Methods and compositions for targeted drug delivery
BR0210915A (pt) 2001-06-08 2004-06-08 Sod Conseils Rech Applic Análogos quiméricos de somatostatina-dopamina
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GB0229020D0 (en) * 2002-12-12 2003-01-15 Novartis Ag Organic compounds
KR101018491B1 (ko) 2002-12-12 2011-03-03 노파르티스 아게 4-히드록시-프롤린 하부구조를 포함하는 펩티드의 합성 방법
GB0300095D0 (en) * 2003-01-03 2003-02-05 Novartis Ag Organic compounds
RU2361876C2 (ru) 2003-04-22 2009-07-20 Сосьете Де Консей Де Решерш Э Д`Аппликасьон Сьентифик С.А.С. Пептидные векторы
AR044852A1 (es) * 2003-06-24 2005-10-05 Novartis Ag Una composicion farmaceutica para la administracion parenteral que comprende un analogo de somatostatina
ATE500264T1 (de) 2003-09-22 2011-03-15 Boehringer Ingelheim Int Makrozyklische peptide mit wirkung gegen das hepatitis-c-virus
EP1522311A1 (fr) 2003-10-10 2005-04-13 Institut National De La Sante Et De La Recherche Medicale (Inserm) Utilisation de la somatostine ou d'un de ses analogues pour préparer un médicament destiné à réguler la réserve folliculaire ovarienne chez la femme non ménopausée
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US7309708B2 (en) 2003-11-20 2007-12-18 Birstol-Myers Squibb Company Hepatitis C virus inhibitors
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EP1717247A1 (en) * 2005-04-28 2006-11-02 Schering AG Cyclic peptides binding to the somatostatin receptor
EP1941902A1 (en) * 2007-01-02 2008-07-09 Novartis AG Use of Somatostatin analogs in cluster headache
UA98494C2 (uk) * 2007-06-29 2012-05-25 Гіліад Сайєнсіз, Інк. Противірусні сполуки
BRPI0813733A2 (pt) 2007-06-29 2019-11-05 Gilead Sciences Inc composto com atividade inibidora de hcv, sua composição farmacêutica e seu uso.
US20100273719A1 (en) 2007-11-28 2010-10-28 Novartis Ag Use of somatostatin analogs in meningioma
US8937152B2 (en) * 2007-12-03 2015-01-20 Italfarmaco Spa Non-selective somatostatin analogues
EP2067786A1 (en) 2007-12-07 2009-06-10 ITALFARMACO S.p.A. Novel non selective analogs of somatostatin
US10240138B2 (en) 2008-06-12 2019-03-26 Ipsen Bioinnovation Limited Polypeptides that bind to and inhibit secretion from growth hormone secreting cells
CN104328100B (zh) 2008-06-12 2019-08-23 益普生生物创新有限公司 神经内分泌病的抑制
PT2310042E (pt) * 2008-07-08 2013-03-11 Novartis Ag Uso de pasireotido para o tratamento de hipoglicemia hiperinsulinémica endógena
EP2213307A1 (en) 2009-02-03 2010-08-04 Novartis AG Injectable depot formulations
EP2172189A1 (en) 2008-10-01 2010-04-07 Novartis AG Pharmaceutical Compositions
EP2168983A1 (fr) 2008-09-30 2010-03-31 Ipsen Pharma Nouveaux composés octapeptidiques et leur utilisation thérapeutique
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer
UY32325A (es) * 2008-12-19 2010-07-30 Gilead Sciences Inc Inhibidores de ns3 proteasa del vhc
EP2380596A1 (en) * 2010-04-20 2011-10-26 Technische Universität München Cyclopentapeptide derivatives and uses thereof
WO2016097962A1 (en) 2014-12-19 2016-06-23 Auro Peptides Ltd A process for the preparation of pasireotide
CN106432429A (zh) * 2016-10-24 2017-02-22 合肥国肽生物科技有限公司 一种帕西瑞肽的合成方法
HRP20231458T1 (hr) 2017-01-12 2024-05-10 Radiomedix Inc. Liječenje stanica raka koje prekomjerno eksprimiraju receptore za somatostatin primjenom derivata oktreotida keliranih sa radioizotopima
TWI888355B (zh) 2018-07-25 2025-07-01 法商高級催化劑應用品有限公司 穩定的、濃縮的放射性核種錯合物溶液
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Also Published As

Publication number Publication date
BR9609335B8 (pt) 2014-10-07
EP0835263A2 (en) 1998-04-15
IL122243A (en) 2005-09-25
WO1997001579A2 (en) 1997-01-16
ES2169251T3 (es) 2002-07-01
KR19990028480A (ko) 1999-04-15
WO1997001579A3 (en) 1997-02-27
US6225284B1 (en) 2001-05-01
DK0835263T3 (da) 2002-04-02
JP2003104998A (ja) 2003-04-09
CN1189166A (zh) 1998-07-29
TW491854B (en) 2002-06-21
IL122243A0 (en) 1998-04-05
AU714447B2 (en) 2000-01-06
SK177097A3 (en) 1998-08-05
HU228984B1 (en) 2013-07-29
NO317867B1 (no) 2004-12-27
PL323943A1 (en) 1998-04-27
EP0835263B9 (en) 2002-07-24
CZ297381B6 (cs) 2006-11-15
PT835263E (pt) 2002-04-29
MY147327A (en) 2012-11-30
ATE210152T1 (de) 2001-12-15
PL184947B1 (pl) 2003-01-31
JP3445796B2 (ja) 2003-09-08
JPH11506108A (ja) 1999-06-02
HUP9901455A3 (en) 2000-11-28
SK284087B6 (sk) 2004-09-08
CA2222524A1 (en) 1997-01-16
NZ313147A (en) 1999-11-29
EP0835263B1 (en) 2001-12-05
AU6515096A (en) 1997-01-30
CZ419697A3 (cs) 1998-05-13
DE69617687D1 (de) 2002-01-17
CN1156492C (zh) 2004-07-07
BR9609335B1 (pt) 2009-08-11
TR199701718T1 (xx) 1998-05-21
DE69617687T2 (de) 2002-08-22
NO976064L (no) 1998-02-16
BR9609335A (pt) 1999-05-25
HUP9901455A2 (hu) 1999-09-28
CA2222524C (en) 2010-01-26
KR100454664B1 (ko) 2005-09-12

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