[go: up one dir, main page]

NO950381L - Nukleinsyresekvens amplifikasjon - Google Patents

Nukleinsyresekvens amplifikasjon

Info

Publication number
NO950381L
NO950381L NO950381A NO950381A NO950381L NO 950381 L NO950381 L NO 950381L NO 950381 A NO950381 A NO 950381A NO 950381 A NO950381 A NO 950381A NO 950381 L NO950381 L NO 950381L
Authority
NO
Norway
Prior art keywords
nucleic acid
acid sequence
sequence amplification
amplification
oligonucleotides
Prior art date
Application number
NO950381A
Other languages
English (en)
Other versions
NO950381D0 (no
Inventor
Sherol H Macdonough
Daniel Louis Kacian
Nanibhushan Dattagupta
Diane L Mcallister
Philip H Hammond
Thomas B Ryder
Original Assignee
Gen Probe Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Probe Inc filed Critical Gen Probe Inc
Publication of NO950381D0 publication Critical patent/NO950381D0/no
Publication of NO950381L publication Critical patent/NO950381L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • AIDS & HIV (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Fremgangsmåte, blanding og kit for å syntetisere multiple kopier av en targetnukleinsyresekvens autolytisk under betingelser med vesentlig konstant temperatur, ionestyrke og pH er tilveiebrakt, hvor multiple RNA kopier av targetsekvensen autolytisk danner ytterligere kopier ved anvendelse av en blanding av blokkerte og ikke-blokkerte primere og/eller promoter-primere til å initiere DNA og RNA syntese, foretrukket med redusert dannelse av ikke-spesifikt produkt. Et av midlene for blokkering eller modifikasjon er alkan-diol som er vist i figuren. Oppfinnelsen kan anvendes for å danne kopier av en nukleinsyretargetsekvens for formål som inkluderer analyser for å kvantifisere spesifikke nuklein-syresekvenser i kliniske prøver, miljøprøver, i forbindelse med rettsmedisin og i liknende prøver, kloning og dannelse av prober.
NO950381A 1992-08-04 1995-02-02 Nukleinsyresekvens amplifikasjon NO950381L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92540592A 1992-08-04 1992-08-04
PCT/US1993/007138 WO1994003472A1 (en) 1992-08-04 1993-07-28 Nucleic acid sequence amplification

Publications (2)

Publication Number Publication Date
NO950381D0 NO950381D0 (no) 1995-02-02
NO950381L true NO950381L (no) 1995-04-03

Family

ID=25451694

Family Applications (1)

Application Number Title Priority Date Filing Date
NO950381A NO950381L (no) 1992-08-04 1995-02-02 Nukleinsyresekvens amplifikasjon

Country Status (11)

Country Link
EP (2) EP0978570B1 (no)
JP (3) JP4372837B2 (no)
KR (1) KR100316498B1 (no)
AT (2) ATE197479T1 (no)
AU (2) AU670116B2 (no)
CA (1) CA2141430C (no)
DE (2) DE69329636T2 (no)
ES (1) ES2277679T3 (no)
NO (1) NO950381L (no)
TW (1) TW278099B (no)
WO (1) WO1994003472A1 (no)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981179A (en) * 1991-11-14 1999-11-09 Digene Diagnostics, Inc. Continuous amplification reaction
EP1251182A3 (en) 1993-12-01 2002-11-27 Toyo Boseki Kabushiki Kaisha Method of amplifying and detecting target nucleic acid sequence by using thermostable enzymes
FR2724934B1 (fr) * 1994-09-26 1997-01-24 Bio Merieux Oligonucleotide chimere et son utilisation dans l'obtention de transcrits d'un acide nucleique
US5514551A (en) * 1994-10-14 1996-05-07 Gen-Probe Incorporated Compositions for the detection of Chlamydia trachomatis
DK0805876T3 (da) * 1995-01-19 2000-11-06 Gen Probe Inc Nukleinsyreamplifikationsoligonukleotider og prober til Lyme-sygdom-associeret Borrelia
US5622827A (en) * 1995-02-07 1997-04-22 Gen-Probe Incorporated Amplification primers and nucleic acid probes targeted to coccidioides immitis nucleic acid
AU693023B2 (en) 1995-05-05 1998-06-18 Applied Biosystems, Llc Methods and reagents for combined PCR amplification and hybridization probing assay
US5925518A (en) * 1995-05-19 1999-07-20 Akzo Nobel N.V. Nucleic acid primers for amplification of a mycobacteria RNA template
US5882857A (en) * 1995-06-07 1999-03-16 Behringwerke Ag Internal positive controls for nucleic acid amplification
CA2223241C (en) * 1995-06-07 2009-11-17 Gen-Probe Incorporated Methods and kits for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
US5739311A (en) * 1995-06-07 1998-04-14 Gen-Probe Incorporated Enzymatic synthesis of phosphorothioate oligonucleotides using restriction endonucleases
US5652126A (en) * 1995-06-07 1997-07-29 Gen-Probe Incorporated Use of restriction endonuclease sequences for cleaving phosphorothioate oligonucleotides
US5916777A (en) * 1995-06-07 1999-06-29 Gen-Probe Incorporated Enzymatic synthesis of oligonucleotides using 3'-ribonucleotide primers
US5705365A (en) * 1995-06-07 1998-01-06 Gen-Probe Incorporated Kits for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
US5747252A (en) 1995-06-07 1998-05-05 Gen-Probe Incorporated Nucleic acid probes and amplification oligonucleotides for Neisseria species
CA2222305A1 (en) * 1995-06-07 1996-12-19 Gen-Probe Incorporated Nucleic acid probes and amplification oligonucleotides for neisseria species
US5932450A (en) * 1995-06-07 1999-08-03 Gen-Probe Incorporated Enzymatic synthesis of oligonucleotides using digestible templates
US5710029A (en) * 1995-06-07 1998-01-20 Gen-Probe Incorporated Methods for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
DE69734576T2 (de) * 1996-03-01 2006-08-03 E.I. Dupont De Nemours And Co., Wilmington Methode zur vervielfältigung und zum nachweis eines gewünschten nukleinsäurefragments
WO1997044488A2 (en) 1996-05-22 1997-11-27 Gen-Probe Incorporated Compositions and methods for the detection of mycobacterium kansasii
US6013488A (en) * 1996-07-25 2000-01-11 The Institute Of Physical And Chemical Research Method for reverse transcription
US6057134A (en) * 1996-10-07 2000-05-02 Ambion, Inc. Modulating the efficiency of nucleic acid amplification reactions with 3' modified oligonucleotides
AU746549B2 (en) 1996-11-20 2002-05-02 Becton Dickinson & Company Microfabricated isothermal nucleic acid amplification devices and methods
GB9626074D0 (en) * 1996-12-16 1997-02-05 Cytocell Ltd Nucleic acids amplification assay
US6025133A (en) * 1996-12-30 2000-02-15 Gen-Probe Incorporated Promoter-sequestered oligonucleoside and method of use
EP0975807B1 (en) 1997-05-02 2006-09-27 Gen-Probe Incorporated Two-step hybridization and capture of a polynucleotide
US6534273B2 (en) 1997-05-02 2003-03-18 Gen-Probe Incorporated Two-step hybridization and capture of a polynucleotide
CN1140632C (zh) * 1997-08-14 2004-03-03 宝酒造株式会社 Dna扩增方法及其试剂盒
WO1999023258A1 (en) * 1997-10-31 1999-05-14 Gen-Probe Incorporated Methods of nucleic acid detection
US5932451A (en) * 1997-11-19 1999-08-03 Incyte Pharmaceuticals, Inc. Method for unbiased mRNA amplification
JP4438110B2 (ja) * 1998-07-01 2010-03-24 東ソー株式会社 標的核酸の定量方法
WO2000070039A1 (en) * 1999-05-17 2000-11-23 Mcgill University METHOD FOR SUBTRACTING cDNAs BY SUPPRESSING THE SYNTHESIS OF SPECIFICALLY TARGETED mRNAs
JP4796252B2 (ja) 1999-07-23 2011-10-19 ジェン−プローブ・インコーポレーテッド ポリヌクレオチド増幅方法
US6489114B2 (en) 1999-12-17 2002-12-03 Bio Merieux Process for labeling a ribonucleic acid, and labeled RNA fragments which are obtained thereby
US6902891B2 (en) 1999-12-17 2005-06-07 Bio Merieux Process for labeling a nucleic acid
JP2002051778A (ja) * 2000-05-31 2002-02-19 Tosoh Corp 小型球形ウイルス（ｓｒｓｖ）ｒｎａ検出のためのオリゴヌクレオチドおよび検出法
AUPR050700A0 (en) 2000-10-03 2000-10-26 Id+Plus Ltd Detection method
AU2001291513B2 (en) * 2000-10-03 2007-06-07 Id+Plus Ltd Nucleotide detection method
ATE386821T1 (de) 2000-10-23 2008-03-15 Gen Probe Inc Zusammensetzungen und methoden zur detektion von humanem immundefizienz virus 2 (hiv-2)
JP2002125688A (ja) * 2000-10-30 2002-05-08 Tosoh Corp Ｃ型肝炎ウイルスの高感度検出のためのオリゴヌクレオチドおよび検出法
DE10119203B4 (de) * 2001-04-19 2004-09-16 Rolf Dr. Postina Verfahren zur Erzeugung von doppelsträngigen Nukleinsäuren mit einzelsträngigen Überhängen beliebiger Länge und Nukleotidzusammensetzung
EP2292801B1 (en) 2002-06-14 2018-08-08 Gen-Probe Incorporated Compositions and methods for detecting hepatitis b virus
EP2977470B1 (en) 2002-10-16 2018-01-03 Gen-Probe Incorporated Compositions and methods for detecting west nile virus
WO2005061738A1 (en) 2003-12-19 2005-07-07 Gen-Probe Incorporated Compositions, methods and kits for detecting the nucleic acids of hiv-1 and hiv-2
DK2975139T3 (da) 2004-09-30 2019-12-09 Gen Probe Inc Assay til at detektere og kvantificere hiv-1
WO2006137939A2 (en) 2004-11-09 2006-12-28 Gen-Probe Incorporated Compositions and methods for detecting group a streptococci
EP1853706B1 (en) 2005-02-18 2010-12-29 Gen-Probe Incorporated Sample preparation method incorporating an alkaline shock
WO2006121773A2 (en) 2005-05-06 2006-11-16 Gen-Probe Incorporated Compositions and assays to detect influenza virus a and b nucleic acids
EP2273404B1 (en) 2005-11-14 2013-10-09 Gen-Probe Incorporated Computer-readable medium for parametric calibration method
EP2027293B1 (en) * 2006-05-24 2014-11-19 Gen-Probe Incorporated Method of lysing mycobacterium and amplifying its nucleic acid
EP1921156A1 (en) 2006-11-10 2008-05-14 bioMerieux B.V. Improved multiplex nucleic acid amplification using blocked primers
GB0701253D0 (en) 2007-01-23 2007-02-28 Diagnostics For The Real World Nucleic acid amplification and testing
EP1978111B1 (en) * 2007-04-02 2013-03-27 Gen-Probe Incorporated Compositions, kits and related methods for the detection and/or monitoring of Pseudomonas aeruginosa
EP2811037B1 (en) 2008-04-21 2017-04-19 Gen-Probe Incorporated Method for detecting Chikungunya virus
AU2010217928B2 (en) 2009-02-26 2013-06-06 Gen-Probe Incorporated Assay for detection of human parvovirus nucleic acid
US9234249B2 (en) 2010-07-12 2016-01-12 Gen-Probe Incorporated Compositions and assays to detect swine H1N1 influenza A virus, seasonal H1 influenza A virus and seasonal H3 influenza A virus nucleic acids
WO2012030856A2 (en) 2010-08-30 2012-03-08 Gen-Probe Incorporated Compositions, methods and reaction mixtures for the detection of xenotropic murine leukemia virus-related virus
JP6150795B2 (ja) 2011-07-15 2017-06-28 ジェン−プロウブ インコーポレイテッド シングルプレックス又はマルチプレックスアッセイにおいてヒトパルボウイルス核酸を検出及びａ型肝炎ウイルス核酸を検出するための組成物及び方法
US9932628B2 (en) 2012-07-27 2018-04-03 Gen-Probe Incorporated Dual reference calibration method and system for quantifying polynucleotides
CN105264090B (zh) 2013-03-15 2020-04-07 简·探针公司 校准方法、设备和计算机程序产品
JP6994513B2 (ja) 2017-03-24 2022-03-04 ジェン－プローブ・インコーポレーテッド 試料中のウイルス病原体を検出するための組成物および方法
CA3241807A1 (en) 2017-03-24 2018-09-27 Gen-Probe Incorporated Compositions and methods for detecting or quantifying parainfluenza virus
CN111094595A (zh) 2017-08-11 2020-05-01 简·探针公司 用于检测金黄色葡萄球菌的组合物和方法
WO2019118735A1 (en) 2017-12-15 2019-06-20 Gen-Probe Incorporated Compositions and methods for detecting toxigenic clostridium difficile
GB2597569B (en) 2018-06-13 2023-01-25 Gen Probe Inc Compositions and methods for detecting group B streptococcus nucleic acid
EP3830302B1 (en) 2018-08-01 2022-10-05 Gen-Probe Incorporated Compositions and methods for detecting nucleic acids of epstein-barr virus
CA3108105A1 (en) 2018-08-08 2020-02-13 Gen-Probe Incorporated Compositions, methods and kits for detecting mycoplasma genitalium
US12454728B2 (en) 2018-08-21 2025-10-28 Gen-Probe Incorporated Compositions and methods for amplifying, detecting or quantifying human cytomegalovirus
WO2020069085A2 (en) 2018-09-27 2020-04-02 Gen-Probe Incorporated Compositions and methods for detecting bordetella pertussis and bordetella parapertussis nucleic acid
WO2020086546A1 (en) 2018-10-22 2020-04-30 Gen-Probe Incorporated Compositions and methods for amplifying, detecting or quantifying human polyomavirus bk virus
AU2020335996A1 (en) 2019-08-23 2022-03-31 Gen-Probe Incorporated Compositions, methods and kits for detecting Treponema pallidum
WO2021046270A1 (en) 2019-09-05 2021-03-11 Gen-Probe Incorporated Detection of chlamydia trachomatis nucleic acid variants
US12037638B2 (en) 2019-12-09 2024-07-16 Gen-Probe Incorporated Quantification of polynucleotide analytes from dried samples
EP4582563A3 (en) 2020-03-04 2025-10-08 Gen-Probe Incorporated Compositions and methods for detecting sars-cov -2 nucleic acid
EP4382624A3 (en) 2021-07-27 2024-09-04 Gen-Probe Incorporated Compositions and methods for detecting salmonella and at least one of c. jejuni, c. coli, shigella, and stec
KR102544380B1 (ko) 2022-01-29 2023-06-16 (주)동방지퍼 지퍼용 슬라이더와 손잡이의 결착방법 및 이로 인해 제조된 지퍼
EP4282980A1 (en) 2022-05-23 2023-11-29 Mobidiag Oy Methods for amplifying a nucleic acid
WO2024054924A1 (en) 2022-09-08 2024-03-14 Gen-Probe Incorporated Method of detecting nucleic acid analytes using dual-specificity primers
WO2024233375A1 (en) 2023-05-05 2024-11-14 Gen-Probe Incorporated Method and system for improving specificity of analyte detection using real-time nucleic acid amplification

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU616646B2 (en) * 1986-11-24 1991-11-07 Gen-Probe Incorporated Nucleic acid probes for detection and/or quantitation of non-viral organisms
IL86724A (en) * 1987-06-19 1995-01-24 Siska Diagnostics Inc Methods and kits for amplification and testing of nucleic acid sequences
US4994368A (en) * 1987-07-23 1991-02-19 Syntex (U.S.A.) Inc. Amplification method for polynucleotide assays
EP0731175A3 (en) * 1989-07-11 2004-05-26 Gen-Probe Incorporated Oligonucleotide probes for HIV nucleic acid
KR950013953B1 (ko) * 1990-01-26 1995-11-18 애보트 래보라토리즈 리가제 연쇄 반응에 적용가능한 표적 핵산의 증폭 방법
AU8920191A (en) * 1990-10-31 1992-05-26 George D. Cimino Methods and compositions for minimizing inhibition of nucleic acid amplification
US5169766A (en) * 1991-06-14 1992-12-08 Life Technologies, Inc. Amplification of nucleic acid molecules
US5521300A (en) * 1991-08-13 1996-05-28 Norval B. Galloway Oligonucleotides complementary to mycobacterial nucleic acids
CA2135073C (en) * 1992-05-06 2002-11-19 Daniel L. Kacian Nucleic acid sequence amplification method, composition and kit

Also Published As

Publication number Publication date
EP0978570B1 (en) 2006-11-29
EP0587298B1 (en) 2000-11-08
KR100316498B1 (ko) 2002-06-20
JP2006238892A (ja) 2006-09-14
EP0587298A2 (en) 1994-03-16
JPH07509368A (ja) 1995-10-19
ATE346954T1 (de) 2006-12-15
EP0587298A3 (en) 1995-08-30
ATE197479T1 (de) 2000-11-11
AU6802796A (en) 1996-12-19
AU4792093A (en) 1994-03-03
EP0978570A3 (en) 2000-04-12
EP0978570A2 (en) 2000-02-09
DE69329636T2 (de) 2001-03-01
CA2141430A1 (en) 1994-02-17
AU670116B2 (en) 1996-07-04
WO1994003472A1 (en) 1994-02-17
NO950381D0 (no) 1995-02-02
DE69334092D1 (de) 2007-01-11
KR950702999A (ko) 1995-08-23
DE69329636D1 (de) 2000-12-14
JP2004194662A (ja) 2004-07-15
ES2277679T3 (es) 2007-07-16
CA2141430C (en) 2009-05-12
TW278099B (no) 1996-06-11
JP3860809B2 (ja) 2006-12-20
DE69334092T2 (de) 2007-07-05
JP4372837B2 (ja) 2009-11-25
AU700253B2 (en) 1998-12-24

Similar Documents

Publication Publication Date Title
NO950381D0 (no) Nukleinsyresekvens amplifikasjon
DE69231664D1 (de) Zyklische dna sequenzierung
DK0519338T3 (da) Forbedrede fremgangsmåder til nukleinsyreamplifikation
EP0674009A3 (en) Method and device for nucleic acid amplification.
BG107861A (en) Isothermal amplification of nucleic acids on a solid support
PL325439A1 (en) Oligonucleotides, method of amplifying nuclein acid and set of means for acrrying out such amplification of nucleic acid
FR2690691B1 (fr) Procede d'amplification d'arn necessitant une seule etape de manipulation.
DE69122712D1 (de) Verfahren zur nukleinsäure hybridisierung und amplifizierung
RU94033149A (ru) Селективный ограничительный фрагмент амплификации: общий метод для днк "фингерпринтинга"
EP0328829A3 (en) Method for affinity assays using target amplification
ATE114651T1 (de) Alkynylamino-nukleotide.
AU3376897A (en) Microfluidic method for nucleic acid amplification
ATE278013T1 (de) In vitro selektionsmethode
DE3873842D1 (de) Verfahren zur gen-amplifikation.
DE69708865D1 (de) Verfahren zur direkten sequenzierung während "template"-amplifikation
NO904634D0 (no) Amplifikasjon av nukleinsyre ved anvendelse av ligerbare,haarnaalsprobe og transkripsjon.
DK0702728T3 (da) Magnetisk cyklusreaktion
DK0871767T3 (da) Fremgangsmåde til amplificering af specifikke nucleinsyresekvenser
FI955619A0 (fi) Menetelmä nukleiinihappojen erityisen herkäksi detektoimiseksi
DK0587331T3 (da) Nukleinsyreprober til Chlamydia pneumoniae.
DK0840802T3 (da) Fremgangsmåde til sekvensering gennem oligomerhybridisering
DE69328951D1 (de) Nukleinsäuresonden für Mykobacterium Tuberkulosis
DE59814032D1 (de) Nucleinsäuremolekül, kit und verwendung
PT916659E (pt) Processo para a producao de formilimidazolos
DE69230345D1 (de) Nachweis von einem genort