NO954426L - Vitamin D amid-derivater - Google Patents
Vitamin D amid-derivaterInfo
- Publication number
- NO954426L NO954426L NO954426A NO954426A NO954426L NO 954426 L NO954426 L NO 954426L NO 954426 A NO954426 A NO 954426A NO 954426 A NO954426 A NO 954426A NO 954426 L NO954426 L NO 954426L
- Authority
- NO
- Norway
- Prior art keywords
- group
- pct
- alpha
- vitamin
- sec
- Prior art date
Links
- 229930003316 Vitamin D Natural products 0.000 title abstract 2
- -1 Vitamin D amide Chemical class 0.000 title abstract 2
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 title abstract 2
- 235000019166 vitamin D Nutrition 0.000 title abstract 2
- 239000011710 vitamin D Substances 0.000 title abstract 2
- 229940046008 vitamin d Drugs 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- OFHCOWSQAMBJIW-AVJTYSNKSA-N alfacalcidol Chemical class C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C OFHCOWSQAMBJIW-AVJTYSNKSA-N 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000000125 calcaemic effect Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000000962 organic group Chemical group 0.000 abstract 1
- 150000003710 vitamin D derivatives Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939309422A GB9309422D0 (en) | 1993-05-07 | 1993-05-07 | Chemical compounds |
| PCT/GB1994/000975 WO1994026707A1 (en) | 1993-05-07 | 1994-05-06 | Vitamin d amide derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO954426D0 NO954426D0 (no) | 1995-11-06 |
| NO954426L true NO954426L (no) | 1996-01-08 |
| NO309187B1 NO309187B1 (no) | 2000-12-27 |
Family
ID=10735089
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO954426A NO309187B1 (no) | 1993-05-07 | 1995-11-06 | Vitamin D-amidderivater, anvendelse, farmasöytiske preparater og fremstilling derav |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5756733A (no) |
| EP (1) | EP0696275B1 (no) |
| JP (1) | JP3703099B2 (no) |
| KR (1) | KR100321414B1 (no) |
| CN (1) | CN1093852C (no) |
| AT (1) | ATE169617T1 (no) |
| AU (1) | AU678246B2 (no) |
| CA (1) | CA2162272A1 (no) |
| CZ (1) | CZ291238B6 (no) |
| DE (1) | DE69412476T2 (no) |
| DK (1) | DK0696275T3 (no) |
| ES (1) | ES2122275T3 (no) |
| FI (1) | FI112361B (no) |
| GB (1) | GB9309422D0 (no) |
| HU (1) | HUT74165A (no) |
| IL (1) | IL109595A (no) |
| NO (1) | NO309187B1 (no) |
| NZ (1) | NZ265665A (no) |
| WO (1) | WO1994026707A1 (no) |
| ZA (1) | ZA943162B (no) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9405715D0 (en) * | 1994-03-23 | 1994-05-11 | Res Inst Medicine Chem | Chemical compounds |
| JP3314938B2 (ja) * | 1995-06-06 | 2002-08-19 | ファイザー・インコーポレーテッド | グリコーゲンホスホリラーゼ抑制剤としての置換されたｎ−（インドール−２−カルボニル）−グリシンアミド類および誘導体 |
| DE19619036A1 (de) | 1996-04-30 | 1997-11-13 | Schering Ag | Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln |
| GB9623569D0 (en) * | 1996-11-13 | 1997-01-08 | Immunodiagnostic Systems Ltd | Vitamin D immumoassay systems |
| US6043385A (en) * | 1997-12-16 | 2000-03-28 | Hoffman-La Roche Inc. | Vitamin D derivatives |
| GB9804861D0 (en) | 1998-03-06 | 1998-04-29 | Res Inst Medicine Chem | Chemical compounds |
| WO2000024712A1 (en) * | 1998-10-23 | 2000-05-04 | Teijin Limited | Vitamin d3 derivatives and remedies for inflammatory respiratory diseases containing the same |
| CN1232244C (zh) * | 1999-02-08 | 2005-12-21 | 阿尔萨公司 | 稳定的非水性单相粘性载体及采用该载体的制剂 |
| DE19935771A1 (de) * | 1999-07-23 | 2001-02-01 | Schering Ag | Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln |
| US6703380B2 (en) | 1999-09-29 | 2004-03-09 | Colotech A/S | Prevention of cancer |
| CA2385755C (en) | 1999-09-29 | 2007-02-06 | Colotech A/S | Prevention of colorectal cancer |
| US6358939B1 (en) | 1999-12-21 | 2002-03-19 | Northern Lights Pharmaceuticals, Llc | Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease |
| US6989377B2 (en) | 1999-12-21 | 2006-01-24 | Wisconsin Alumni Research Foundation | Treating vitamin D responsive diseases |
| ATE509910T1 (de) | 2000-06-15 | 2011-06-15 | Chugai Pharmaceutical Co Ltd | Vitamin d derivate mit einem 22-oxa- oder 22-thia-atom, einer sauer-, ester- oder amid- substitutierten c17-seitenkette und einer 16(17)- doppelbindung |
| CN101462994B (zh) * | 2000-06-15 | 2012-11-28 | 中外制药株式会社 | 维生素d衍生物 |
| US6277877B1 (en) | 2000-08-15 | 2001-08-21 | Pfizer, Inc. | Substituted n-(indole-2-carbonyl)glycinamides and derivates as glycogen phosphorylase inhibitors |
| RU2323926C2 (ru) * | 2000-12-08 | 2008-05-10 | Чугаи Сейяку Кабусики Кайся | Способ карбонилирования |
| ATE413388T1 (de) * | 2002-04-26 | 2008-11-15 | Schering Corp | Muskarin antagonisten |
| EP2025667B1 (en) * | 2006-06-02 | 2016-08-10 | Nippon Shinyaku Co., Ltd. | 9,10-secopregnane derivative and pharmaceutical |
| WO2009117831A1 (en) * | 2008-03-27 | 2009-10-01 | The Royal Institution For The Advancement Of Learning/Mcgill University | Hybrid molecules having mixed vitamin d receptor agonism and histone deacetylase inhibitory properties |
| CA2750659C (en) | 2009-01-27 | 2017-11-21 | Berg Biosystems, Llc | Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy |
| EA201270226A1 (ru) | 2009-08-14 | 2012-09-28 | БЕРГ БАЙОСИСТЕМЗ, ЭлЭлСи | Витамин d3 и его аналогии для лечения алопеции |
| WO2012151058A1 (en) | 2011-05-03 | 2012-11-08 | Wisconsin Alumni Research Foundation | (20s)-24-(p-toluenesulfonyloxy)-25,26,27-trinorvitamin d3 analogs and their uses |
| US8987235B2 (en) | 2011-05-17 | 2015-03-24 | Wisconsin Alumni Research Foundation | N-cyclopropyl-(20R)-2-methylene-19,26,27-trinor-25-aza-vitamin D analogs and their uses |
| HK1222819A1 (zh) | 2013-05-29 | 2017-07-14 | 博格有限责任公司 | 使用维生素d预防或减轻化疗诱发的脱发 |
| US9338493B2 (en) | 2014-06-30 | 2016-05-10 | Apple Inc. | Intelligent automated assistant for TV user interactions |
| US10548908B2 (en) | 2016-09-15 | 2020-02-04 | Nostopharma, LLC | Compositions and methods for preventing and treating heterotopic ossification and pathologic calcification |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8929059D0 (en) * | 1989-12-22 | 1990-02-28 | Leo Pharm Prod Ltd | Chemical compounds |
| WO1993009093A1 (en) * | 1991-11-07 | 1993-05-13 | Holmes, Michael, John | Vitamin d amide derivatives |
-
1993
- 1993-05-07 GB GB939309422A patent/GB9309422D0/en active Pending
-
1994
- 1994-05-06 AU AU66832/94A patent/AU678246B2/en not_active Ceased
- 1994-05-06 CN CN94192435A patent/CN1093852C/zh not_active Expired - Fee Related
- 1994-05-06 ZA ZA943162A patent/ZA943162B/xx unknown
- 1994-05-06 JP JP52511994A patent/JP3703099B2/ja not_active Expired - Fee Related
- 1994-05-06 EP EP94914472A patent/EP0696275B1/en not_active Expired - Lifetime
- 1994-05-06 CA CA002162272A patent/CA2162272A1/en not_active Abandoned
- 1994-05-06 NZ NZ265665A patent/NZ265665A/en unknown
- 1994-05-06 DK DK94914472T patent/DK0696275T3/da active
- 1994-05-06 CZ CZ19952903A patent/CZ291238B6/cs not_active IP Right Cessation
- 1994-05-06 DE DE69412476T patent/DE69412476T2/de not_active Expired - Fee Related
- 1994-05-06 WO PCT/GB1994/000975 patent/WO1994026707A1/en not_active Ceased
- 1994-05-06 US US08/532,799 patent/US5756733A/en not_active Expired - Fee Related
- 1994-05-06 HU HU9503190A patent/HUT74165A/hu unknown
- 1994-05-06 AT AT94914472T patent/ATE169617T1/de not_active IP Right Cessation
- 1994-05-06 ES ES94914472T patent/ES2122275T3/es not_active Expired - Lifetime
- 1994-05-06 KR KR1019950704980A patent/KR100321414B1/ko not_active Expired - Fee Related
- 1994-05-08 IL IL10959594A patent/IL109595A/xx not_active IP Right Cessation
-
1995
- 1995-11-06 NO NO954426A patent/NO309187B1/no unknown
- 1995-11-06 FI FI955316A patent/FI112361B/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU678246B2 (en) | 1997-05-22 |
| NO954426D0 (no) | 1995-11-06 |
| NZ265665A (en) | 1997-05-26 |
| CA2162272A1 (en) | 1994-11-24 |
| DE69412476T2 (de) | 1999-03-11 |
| ATE169617T1 (de) | 1998-08-15 |
| JPH08509971A (ja) | 1996-10-22 |
| US5756733A (en) | 1998-05-26 |
| HU9503190D0 (en) | 1996-01-29 |
| CN1125436A (zh) | 1996-06-26 |
| CN1093852C (zh) | 2002-11-06 |
| WO1994026707A1 (en) | 1994-11-24 |
| DE69412476D1 (de) | 1998-09-17 |
| ES2122275T3 (es) | 1998-12-16 |
| IL109595A0 (en) | 1994-08-26 |
| NO309187B1 (no) | 2000-12-27 |
| FI112361B (fi) | 2003-11-28 |
| EP0696275A1 (en) | 1996-02-14 |
| CZ290395A3 (en) | 1996-06-12 |
| JP3703099B2 (ja) | 2005-10-05 |
| DK0696275T3 (da) | 1998-11-09 |
| HUT74165A (en) | 1996-11-28 |
| ZA943162B (en) | 1995-04-13 |
| AU6683294A (en) | 1994-12-12 |
| GB9309422D0 (en) | 1993-06-23 |
| EP0696275B1 (en) | 1998-08-12 |
| KR100321414B1 (ko) | 2002-12-05 |
| FI955316A7 (fi) | 1995-12-22 |
| FI955316A0 (fi) | 1995-11-06 |
| IL109595A (en) | 1999-04-11 |
| CZ291238B6 (cs) | 2003-01-15 |
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