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NO943140D0 - Heterobicykliske forbindelser - Google Patents

Heterobicykliske forbindelser

Info

Publication number
NO943140D0
NO943140D0 NO943140A NO943140A NO943140D0 NO 943140 D0 NO943140 D0 NO 943140D0 NO 943140 A NO943140 A NO 943140A NO 943140 A NO943140 A NO 943140A NO 943140 D0 NO943140 D0 NO 943140D0
Authority
NO
Norway
Prior art keywords
heterobicyclic compounds
heterobicyclic
compounds
Prior art date
Application number
NO943140A
Other languages
English (en)
Other versions
NO943140L (no
Inventor
Amedeo Leonardi
Gianni Motta
Carlo Riva
Rodolfo Testa
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ITMI920408A external-priority patent/IT1254469B/it
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Publication of NO943140L publication Critical patent/NO943140L/no
Publication of NO943140D0 publication Critical patent/NO943140D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/322,3-Dihydro derivatives, e.g. flavanones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D335/00Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06Benzothiopyrans; Hydrogenated benzothiopyrans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
NO943140A 1992-02-25 1994-08-25 Heterobicykliske forbindelser NO943140D0 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI920408A IT1254469B (it) 1992-02-25 1992-02-25 Derivati benzopiranici e benzotiopiranici
US07/888,775 US5403842A (en) 1992-02-25 1992-05-26 Benzopyran and benzothiopyran derivatives
PCT/EP1993/000420 WO1993017007A1 (en) 1992-02-25 1993-02-23 Heterobicyclic compounds

Publications (2)

Publication Number Publication Date
NO943140L NO943140L (no) 1994-08-25
NO943140D0 true NO943140D0 (no) 1994-08-25

Family

ID=26330842

Family Applications (1)

Application Number Title Priority Date Filing Date
NO943140A NO943140D0 (no) 1992-02-25 1994-08-25 Heterobicykliske forbindelser

Country Status (25)

Country Link
EP (1) EP0558245A1 (no)
JP (1) JPH069606A (no)
AU (2) AU3629693A (no)
BG (1) BG61946B1 (no)
CA (1) CA2090156A1 (no)
CZ (1) CZ205994A3 (no)
DZ (1) DZ1666A1 (no)
EE (1) EE03177B1 (no)
EG (1) EG20333A (no)
FI (1) FI943876A0 (no)
HR (1) HRP930210A2 (no)
HU (1) HUT72448A (no)
IL (1) IL104824A (no)
LT (1) LT3038B (no)
LV (1) LV10099B (no)
MX (1) MX9300977A (no)
NO (1) NO943140D0 (no)
NZ (1) NZ245995A (no)
PL (1) PL175556B1 (no)
SG (1) SG65570A1 (no)
SI (1) SI9300094A (no)
SK (1) SK280143B6 (no)
TW (1) TW382628B (no)
WO (1) WO1993017007A1 (no)
ZA (1) ZA931278B (no)

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MX9300312A (es) * 1992-01-23 1993-07-31 Pfizer Antagonistas benzopiranicos y relacionado de ltb.
FR2689127B1 (fr) * 1992-03-31 1994-05-06 Adir Cie Nouvelles 3', 5' -ditertbutyl-4'-hydroxy flavones, leur procede de preparation et les compositions pharmaceutiques les renfermant.
IT1266582B1 (it) * 1993-07-30 1997-01-09 Recordati Chem Pharm Derivati (di)azacicloesanici e diazacicloeptanici
GB9317071D0 (en) * 1993-08-17 1993-09-29 Univ Strathclyde Flavonoids
JP3426242B2 (ja) * 1994-01-14 2003-07-14 株式会社アズウェル ジアザシクロアルカンアルキルスルホンアミド誘導体
FR2717175B1 (fr) * 1994-03-11 1996-06-14 Adir Nouveaux composés alkylaminoindanes, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
ES2101620B1 (es) * 1994-03-18 1998-04-01 Ferrer Int Nuevo compuesto derivado del cromeno.
IL112764A0 (en) * 1994-03-18 1995-05-26 Ferrer Int New chromene derivatives
CN1067985C (zh) * 1994-03-30 2001-07-04 泽里新药工业株式会社 吲哚衍生物及含它们的药物
US5503843A (en) * 1994-04-22 1996-04-02 Flora Inc. Transdermal delivery of alpha adrenoceptor blocking agents
DE4425146A1 (de) * 1994-07-15 1996-01-18 Basf Ag Verwendung heterocyclischer Verbindungen
GB9417135D0 (en) * 1994-08-23 1994-10-12 Medinnova S F Method
KR100502229B1 (ko) * 1995-02-28 2005-11-08 다이이찌 산토리 파마 가부시키가이샤 아릴피페리딘및아릴피페라진유도체,및이를함유하는약제
GB9507288D0 (en) 1995-04-07 1995-05-31 Sod Conseils Rech Applic Phenoxyethylamine derivatives with high affinity for 5-HT1A receptors
US5859014A (en) * 1995-06-09 1999-01-12 Syntex (U.S.A.) Inc. Pyrimidinedione, pyrimidinetrione, triazinedione and tetrahydroquinazolinedione derivatives as α1 -adrenergic receptor antagonists
DK0748800T3 (da) * 1995-06-09 2001-08-27 Hoffmann La Roche Pyrimidindion-, pyrimidintrion- og triazindionderivater som alfa-1-adrenergiske receptorantagonister
JPH0967367A (ja) * 1995-06-23 1997-03-11 Suntory Ltd チオピラン誘導体
WO1997014419A1 (en) * 1995-10-20 1997-04-24 Flora Inc. Transdermal delivery of alpha adrenoceptor blocking agents
IT1282705B1 (it) * 1996-02-28 1998-03-31 Recordati Chem Pharm Uso di antagonisti del recettore serotoninergico 5-ht|a per il trattamento dell'incontinenza urinaria
US5990114A (en) * 1996-02-28 1999-11-23 Recordati, S.A., Chemical And Pharmaceutical Company Use of 5-HT1A receptor antagonists for the treatment of urinary incontinence
FR2745815B1 (fr) * 1996-03-08 1998-06-26 Synthelabo Derives de benzofurane, leur preparations et compositions pharmaceutiques les comprenant
EP0888324A1 (fr) * 1996-03-08 1999-01-07 Synthelabo Derives de 2-aminoethyl-benzofurane, leur preparation et leur application en therapeutique
IL128629A0 (en) * 1996-08-22 2000-01-31 Hoechst Marion Roussel Inc Troponyl piperazines as selective dopamine D4 receptor ligands
TR199902971T2 (xx) 1997-05-12 2001-03-21 Ortho-Mcneil Pharmaceutical, Inc. Selim prostat hiperplazisinin tedavisinde yararl� aril ikameli piperazinler.
AU2002300904B2 (en) * 1997-05-12 2004-12-23 Ortho-Mcneil Pharmaceutical, Inc. Arylsubstituted piperazines useful in the treatment of benign prostatic hyperplasia
DE69818079T2 (de) 1997-06-04 2004-06-03 Azwell Inc. Verfahren zur herstellung von piperazinsulfonamid-derivaten und ihren salzen
WO1999003833A1 (fr) * 1997-07-15 1999-01-28 Sankyo Company, Limited Derives de piperazine
IT1313581B1 (it) * 1999-07-30 2002-09-09 Recordati Chem Pharm Derivati tienopirancarbossamidici.
US6306861B1 (en) 1999-07-30 2001-10-23 Recordati S.A. Chemical And Pharmaceutical Company Thienopyrancecarboxamide derivatives
US6387909B1 (en) 1999-07-30 2002-05-14 Recordati S.A. Chemical And Pharmaceutical Company Thienopyranecarboxamide derivatives
DE19941657A1 (de) * 1999-09-01 2001-03-08 Schwabe Willmar Gmbh & Co Zimtsäurenitrile, Verfahren zu ihrer Herstellung und Verwendung
US6403594B1 (en) 1999-10-18 2002-06-11 Recordati, S.A. Chemical And Pharmaceutical Company Benzopyran derivatives
IT1314192B1 (it) * 1999-10-18 2002-12-06 Recordati Chem Pharm Derivati benzopiranici
JP2002113006A (ja) 2000-10-10 2002-04-16 Toshiba Medical System Co Ltd 診断機器設定方法および診断装置
CN1150176C (zh) 2002-05-22 2004-05-19 上海医药工业研究院 芳烷酮哌嗪衍生物及其应用
WO2004041279A1 (en) * 2002-10-30 2004-05-21 Merck & Co., Inc. Gamma-aminoamide modulators of chemokine receptor activity
US7868037B2 (en) 2004-07-14 2011-01-11 Ptc Therapeutics, Inc. Methods for treating hepatitis C
EP1771169A1 (en) 2004-07-14 2007-04-11 PTC Therapeutics, Inc. Methods for treating hepatitis c
US7781478B2 (en) 2004-07-14 2010-08-24 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US7772271B2 (en) 2004-07-14 2010-08-10 Ptc Therapeutics, Inc. Methods for treating hepatitis C
JP2008507518A (ja) 2004-07-22 2008-03-13 ピーティーシー セラピューティクス,インコーポレーテッド C型肝炎を治療するためのチエノピリジン
TW200640931A (en) 2005-02-17 2006-12-01 Wyeth Corp Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives
CA2738809C (en) * 2008-09-29 2015-11-24 Sirtris Pharmaceuticals, Inc. Quinazolinone, quinolone and related analogs as sirtuin modulators
CZ2012242A3 (cs) 2012-04-10 2013-09-04 Univerzita Palackého Pouzití komplexu medi obsahujících 2-fenyl-3-hydroxychinolin-4(1H)-on a deriváty 1,10-fenanthrolinu pro prípravu léciv pro lécbu nádorových onemocnení
JP2019508400A (ja) 2016-02-09 2019-03-28 ファーマケア,インク. キノリノンリシルオキシダーゼ様2阻害剤とその使用
WO2020095912A1 (ja) * 2018-11-06 2020-05-14 第一三共株式会社 ベンズイミダゾール誘導体
WO2021097475A1 (en) * 2019-11-11 2021-05-20 Southwest Research Institute Recrystallized hi-6 dimethylsulfate
LT4069691T (lt) 2019-12-06 2024-12-10 Vertex Pharmaceuticals Incorporated Pakeistieji tetrahidrofuranai kaip natrio kanalų moduliatoriai
DK4347031T3 (da) 2021-06-04 2025-12-01 Vertex Pharma N-(hydroxyalkyl-(hetero)aryl)-tetrahydrofuran-carboxamider som modulatorer af natriumkanaler
KR20240144096A (ko) 2021-11-02 2024-10-02 플레어 테라퓨틱스 인크. Pparg 역 효능제 및 그의 용도
CN115160279B (zh) * 2022-07-27 2023-11-24 中国药科大学 苯并吡喃酮类化合物、药物组合物和应用

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GB1156973A (en) 1965-07-06 1969-07-02 Quinazoline Derivatives
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NZ200981A (en) 1981-07-17 1984-10-19 Recordati Chem Pharm 3-methylflavone-8-carboxylic acid derivatives and pharmaceutical compositions
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JPS63139180A (ja) * 1986-12-02 1988-06-10 Tanabe Seiyaku Co Ltd カルボン酸誘導体
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US5278174A (en) * 1990-06-04 1994-01-11 Scios Nova, Inc. Sigma binding site agents

Also Published As

Publication number Publication date
PL175556B1 (pl) 1999-01-29
BG98990A (bg) 1995-05-31
FI943876A7 (fi) 1994-08-23
LTIP354A (lt) 1994-04-25
LV10099A (lv) 1994-05-10
AU3629693A (en) 1993-09-13
SK280143B6 (sk) 1999-09-10
JPH069606A (ja) 1994-01-18
LV10099B (en) 1995-02-20
LT3038B (en) 1994-09-25
NZ245995A (en) 1994-09-27
NO943140L (no) 1994-08-25
FI943876A0 (fi) 1994-08-23
DZ1666A1 (fr) 2002-02-17
WO1993017007A1 (en) 1993-09-02
IL104824A (en) 1999-12-22
AU3377393A (en) 1993-08-26
SK100794A3 (en) 1995-04-12
MX9300977A (es) 1993-12-01
TW382628B (en) 2000-02-21
HUT72448A (en) 1996-04-29
EG20333A (en) 1998-10-31
CZ205994A3 (en) 1995-02-15
HRP930210A2 (en) 1995-06-30
BG61946B1 (bg) 1998-10-30
AU660067B2 (en) 1995-06-08
HU9402443D0 (en) 1994-10-28
SI9300094A (en) 1993-09-30
IL104824A0 (en) 1993-06-10
SG65570A1 (en) 1999-06-22
EP0558245A1 (en) 1993-09-01
EE03177B1 (et) 1999-04-15
CA2090156A1 (en) 1993-08-26
ZA931278B (en) 1993-11-18

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