NO940883L - Tricyklisk heterocyklylforbindelse - Google Patents
Tricyklisk heterocyklylforbindelseInfo
- Publication number
- NO940883L NO940883L NO940883A NO940883A NO940883L NO 940883 L NO940883 L NO 940883L NO 940883 A NO940883 A NO 940883A NO 940883 A NO940883 A NO 940883A NO 940883 L NO940883 L NO 940883L
- Authority
- NO
- Norway
- Prior art keywords
- group
- tricyclic heterocyclyl
- heterocyclyl compound
- lower alkyl
- alkyl group
- Prior art date
Links
- -1 heterocyclyl compound Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 102000001494 Sterol O-Acyltransferase Human genes 0.000 abstract 1
- 108010054082 Sterol O-acyltransferase Proteins 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Tricykliské heterocyklyl- forbindelser av generell formel (I): C J) O II as (S) -A-C-NRqR n hvori: R og R hver betegner H, en lavere alkyl- eller lavere alkoxy- gruppe, et halogenatom eller halogen- lavere alkyl; R betegner H eller en 4 lavere alkylgruppe; R betegner en substituert fenyl- eller nafthyl- gruppe; R betegner H eller en lavere alkylgruppe; A betegner en lavere alkylengruppe; B betegner en -0- eller -S-gruppe; og n er O - 1. Forbindelsene har en glimrende akti- vitet ved inhibering av acyl-CoA: kolesterol acyltransferase (ACAT) og er anvendbare ved behandling og pro- fylakse av athereosklerose.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23483491 | 1991-09-13 | ||
| PCT/JP1992/001164 WO1993006096A1 (fr) | 1991-09-13 | 1992-09-11 | Compose heterocyclique tricyclique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO940883D0 NO940883D0 (no) | 1994-03-11 |
| NO940883L true NO940883L (no) | 1994-05-13 |
Family
ID=26433476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO940883A NO940883L (no) | 1991-09-13 | 1994-03-11 | Tricyklisk heterocyklylforbindelse |
Country Status (1)
| Country | Link |
|---|---|
| NO (1) | NO940883L (no) |
-
1994
- 1994-03-11 NO NO940883A patent/NO940883L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO940883D0 (no) | 1994-03-11 |
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