NO940598D0 - Glykosfingolipider og anvendelse derav - Google Patents
Glykosfingolipider og anvendelse deravInfo
- Publication number
- NO940598D0 NO940598D0 NO940598A NO940598A NO940598D0 NO 940598 D0 NO940598 D0 NO 940598D0 NO 940598 A NO940598 A NO 940598A NO 940598 A NO940598 A NO 940598A NO 940598 D0 NO940598 D0 NO 940598D0
- Authority
- NO
- Norway
- Prior art keywords
- sphingoglycolipid
- integer
- glycosphingolipids
- chem
- isopropyl
- Prior art date
Links
- 150000002339 glycosphingolipids Chemical class 0.000 title 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
- 241001251200 Agelas Species 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229940034982 antineoplastic agent Drugs 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000091 immunopotentiator Effects 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Wood Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- External Artificial Organs (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3244384A JPH0559081A (ja) | 1991-08-29 | 1991-08-29 | 新規スフインゴ糖脂質、その製造法および使用 |
| PCT/JP1992/000561 WO1993005055A1 (fr) | 1991-08-29 | 1992-04-28 | Nouveau sphingoglycolipide et son utilisation |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO940598D0 true NO940598D0 (no) | 1994-02-22 |
| NO940598L NO940598L (no) | 1994-04-27 |
| NO180338B NO180338B (no) | 1996-12-23 |
| NO180338C NO180338C (no) | 1997-04-02 |
Family
ID=17117885
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO940598A NO180338C (no) | 1991-08-29 | 1994-02-22 | Glycosfingolipider, fremgangsmåte til fremstilling av slike, antitumormiddel og immunostimulator |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0609437B1 (no) |
| JP (2) | JPH0559081A (no) |
| KR (1) | KR100220793B1 (no) |
| AT (1) | ATE181922T1 (no) |
| AU (1) | AU665536B2 (no) |
| CA (1) | CA2116442C (no) |
| DE (1) | DE69229557T2 (no) |
| DK (1) | DK0609437T3 (no) |
| ES (1) | ES2134213T3 (no) |
| FI (1) | FI105189B (no) |
| GR (1) | GR3030723T3 (no) |
| HU (1) | HU223839B1 (no) |
| NO (1) | NO180338C (no) |
| PT (1) | PT100736B (no) |
| SG (1) | SG44031A1 (no) |
| TW (1) | TW197446B (no) |
| WO (1) | WO1993005055A1 (no) |
| ZA (1) | ZA923239B (no) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5936076A (en) * | 1991-08-29 | 1999-08-10 | Kirin Beer Kabushiki Kaisha | αgalactosylceramide derivatives |
| TW261533B (no) * | 1992-07-16 | 1995-11-01 | Kirin Brewery | |
| US5849716A (en) * | 1992-10-22 | 1998-12-15 | Kirin Beer Kabushiki Kaisha | Sphingoglycolipids, their preparation, and therapeutic methods of use |
| ATE176237T1 (de) * | 1993-04-15 | 1999-02-15 | Kirin Brewery | Sphingoglycolipid und verwendung davon |
| TW555562B (en) | 1996-12-27 | 2003-10-01 | Kirin Brewery | Method for activation of human antigen-presenting cells, activated human antigen-presenting cells and use thereof |
| TW575420B (en) * | 1997-09-22 | 2004-02-11 | Kirin Brewery | Composition for enhancing cellular immunogenicity comprising alpha-glycosylceramides |
| CN100384472C (zh) * | 2000-01-14 | 2008-04-30 | 明治乳业株式会社 | 抗原特异性IgE抗体产生抑制剂 |
| JP2002030093A (ja) * | 2000-03-13 | 2002-01-29 | Nof Corp | グリコシルセラミドの精製方法 |
| EP1437358B1 (en) * | 2001-08-16 | 2006-10-18 | Daiichi Asubio Pharma Co., Ltd. | Novel glycolipid and remedial agent for autoimmune disease containing the same as active ingredient |
| EP1541153A1 (en) * | 2002-09-20 | 2005-06-15 | Kirin Beer Kabushiki Kaisha | Hepatitis c virus inhibitor comprising alpha-glycosylceramide as the active ingredient |
| JP4585172B2 (ja) * | 2003-01-31 | 2010-11-24 | 森永乳業株式会社 | 骨形成促進剤 |
| US7732583B2 (en) * | 2003-02-14 | 2010-06-08 | Japan As Represented By President Of National Center Of Neurology And Psychiatry | Glycolipids and synthetic method thereof as well as their synthetic intermediates, and synthetic intermediates, and synthetic method thereof |
| WO2006068041A1 (ja) * | 2004-12-20 | 2006-06-29 | Okayasu Shoten Co., Ltd. | 体内脂肪の分解促進作用を有する組成物及びそれを含有する食品又は食品配合剤 |
| JP2007070311A (ja) * | 2005-09-09 | 2007-03-22 | Gunma Univ | α−ガラクトシルセラミドからなる感染症予防剤及び感染症治療剤 |
| EP1776963A1 (en) | 2005-10-19 | 2007-04-25 | Gbf-Gesellschaft Für Biotechnologische Forschung Mbh | Hexosylceramides as adjuvants and their uses in pharmaceutical compositions |
| WO2008047174A1 (en) * | 2006-10-18 | 2008-04-24 | Centre National De La Recherche Scientifique | Alpha-galactosylceramide analogs, their methods of manufacture, intermediate compounds useful in these methods, and pharmaceutical compositions containing them |
| KR100868959B1 (ko) * | 2006-12-30 | 2008-11-17 | 재단법인서울대학교산학협력재단 | 알파-갈락토실세라마이드 유도체, 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는면역보조용 약학적 조성물 |
| JP2010519274A (ja) | 2007-02-21 | 2010-06-03 | フラームス・インテルウニフェルシタイル・インステイチュート・フォール・ビオテヒノロヒー・ヴェーゼットウェー(ヴェーイーベー・ヴェーゼットウェー) | TNFおよびα−ガラクトシルセラミドを使用する併用療法 |
| JP4995172B2 (ja) * | 2008-10-10 | 2012-08-08 | 壽製薬株式会社 | 糖脂質誘導体、その製造方法並びにそれを有効成分とする医薬 |
| SMT201700203T1 (it) | 2009-02-16 | 2017-05-08 | Cerenis Therapeutics Holding Sa | Mimetici di apolipoproteina a-i |
| JP5095683B2 (ja) * | 2009-07-06 | 2012-12-12 | 壽製薬株式会社 | 新規糖脂質誘導体及びこれを有効成分とする製剤 |
| JP5025692B2 (ja) * | 2009-07-06 | 2012-09-12 | 壽製薬株式会社 | 糖脂質誘導体の製造方法 |
| JP2010254718A (ja) * | 2010-08-13 | 2010-11-11 | Morinaga Milk Ind Co Ltd | 骨形成促進剤 |
| SG2014012850A (en) | 2010-10-18 | 2014-05-29 | Cerenis Therapeutics Holding Sa | Compounds, compositions and methods useful for cholesterol mobilisation |
| US10813950B2 (en) | 2010-12-02 | 2020-10-27 | Riken | Immunotherapy using allo-NKT cells, cells for immunotherapy in which alpha chain of t-cell receptor (TCR) gene has been rearranged to uniform Vα-Jα, and banking of NKT cells derived from said cells |
| EP2881400A4 (en) * | 2012-08-03 | 2016-02-24 | Riken | HYDROXYLATED KRN7000 ANALOGON AND USE THEREOF |
| US20150224129A1 (en) | 2012-10-03 | 2015-08-13 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for the prophylactic treatment of bacterial superinfections post-influenza with invariant nkt cell agonists |
| WO2014079946A1 (en) | 2012-11-21 | 2014-05-30 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for determining the risk of acute graft versus host disease |
| WO2017207040A1 (en) | 2016-06-01 | 2017-12-07 | Vib Vzw | ANTI-CANCER THERAPY USING A LEPTIN ANTAGONIST AND AN iNKT-CELL ACTIVATOR |
| KR102328367B1 (ko) * | 2019-11-05 | 2021-11-18 | 한국해양과학기술원 | 아젤록심 d를 유효성분으로 함유하는 방사선 민감성 증진용 조성물 |
| IL303285A (en) | 2020-12-04 | 2023-07-01 | Regimmune Corp | Cd1d-ligand-compound-containing liposome preparation having improved pharmacokinetics |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6157594A (ja) * | 1984-08-30 | 1986-03-24 | Suntory Ltd | ガラクトスフインゴ脂質及びその製造法 |
| JP2588729B2 (ja) * | 1987-10-05 | 1997-03-12 | 塩野義製薬株式会社 | スフィンゴシン誘導体 |
| DE3840044A1 (de) * | 1988-11-27 | 1990-06-07 | Behringwerke Ag | Glykosphingolipide mit kopplungsfaehiger gruppe im sphingoidanteil, ihre herstellung und verwendung |
| JP3068910B2 (ja) * | 1990-11-08 | 2000-07-24 | 麒麟麦酒株式会社 | 新規スフィンゴ糖脂質、その製造法および使用 |
-
1991
- 1991-08-29 JP JP3244384A patent/JPH0559081A/ja active Pending
-
1992
- 1992-04-28 JP JP4508706A patent/JP2774194B2/ja not_active Expired - Lifetime
- 1992-04-28 SG SG1996009529A patent/SG44031A1/en unknown
- 1992-04-28 WO PCT/JP1992/000561 patent/WO1993005055A1/ja not_active Ceased
- 1992-04-28 ES ES92909489T patent/ES2134213T3/es not_active Expired - Lifetime
- 1992-04-28 CA CA002116442A patent/CA2116442C/en not_active Expired - Lifetime
- 1992-04-28 DE DE69229557T patent/DE69229557T2/de not_active Expired - Lifetime
- 1992-04-28 HU HU9400596A patent/HU223839B1/hu active IP Right Grant
- 1992-04-28 EP EP92909489A patent/EP0609437B1/en not_active Expired - Lifetime
- 1992-04-28 AU AU16664/92A patent/AU665536B2/en not_active Expired
- 1992-04-28 AT AT92909489T patent/ATE181922T1/de active
- 1992-04-28 KR KR1019940700662A patent/KR100220793B1/ko not_active Expired - Fee Related
- 1992-04-28 DK DK92909489T patent/DK0609437T3/da active
- 1992-05-05 ZA ZA923239A patent/ZA923239B/xx unknown
- 1992-05-06 TW TW081103536A patent/TW197446B/zh not_active IP Right Cessation
- 1992-07-28 PT PT100736A patent/PT100736B/pt not_active IP Right Cessation
-
1994
- 1994-02-22 NO NO940598A patent/NO180338C/no not_active IP Right Cessation
- 1994-02-23 FI FI940851A patent/FI105189B/fi not_active IP Right Cessation
-
1999
- 1999-07-08 GR GR990400800T patent/GR3030723T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU665536B2 (en) | 1996-01-11 |
| CA2116442A1 (en) | 1993-03-18 |
| EP0609437A1 (en) | 1994-08-10 |
| NO940598L (no) | 1994-04-27 |
| DK0609437T3 (da) | 2000-01-31 |
| FI940851A7 (fi) | 1994-02-23 |
| DE69229557D1 (de) | 1999-08-12 |
| GR3030723T3 (en) | 1999-11-30 |
| SG44031A1 (en) | 1997-11-14 |
| NO180338C (no) | 1997-04-02 |
| HK1009967A1 (en) | 1999-09-17 |
| PT100736B (pt) | 1999-04-30 |
| JP2774194B2 (ja) | 1998-07-09 |
| HU223839B1 (hu) | 2005-02-28 |
| PT100736A (pt) | 1993-09-30 |
| WO1993005055A1 (fr) | 1993-03-18 |
| KR100220793B1 (ko) | 1999-10-01 |
| TW197446B (no) | 1993-01-01 |
| ATE181922T1 (de) | 1999-07-15 |
| JPH0559081A (ja) | 1993-03-09 |
| ES2134213T3 (es) | 1999-10-01 |
| AU1666492A (en) | 1993-04-05 |
| HUT70435A (en) | 1995-10-30 |
| FI940851A0 (fi) | 1994-02-23 |
| NO180338B (no) | 1996-12-23 |
| HU9400596D0 (en) | 1994-05-30 |
| ZA923239B (en) | 1993-05-05 |
| DE69229557T2 (de) | 1999-11-25 |
| CA2116442C (en) | 2000-09-05 |
| FI105189B (fi) | 2000-06-30 |
| EP0609437B1 (en) | 1999-07-07 |
| EP0609437A4 (en) | 1994-08-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |