NO932636L - Benzimidazoles, drugs containing these compounds, and methods for their preparation - Google Patents

Benzimidazoles, drugs containing these compounds, and methods for their preparation

Info

Publication number: NO932636L
Authority: NO; Norway
Prior art keywords: benzimidazoles; compounds; preparation; methods; drugs containing
Prior art date: 1992-07-22

Application number

NO932636A

Other languages

Norwegian (no)

Other versions

NO932636D0 (en

NO300772B1 (en

Inventor

Norbert Hauel

Uwe Ries

Van Jacques Meel

Wolfgang Wienen

Michael Entzeroth

Original Assignee

Thomae Gmbh Dr K

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-07-22

Filing date

1993-07-21

Publication date

1994-01-24

1993-07-21 Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K

1993-07-21 Publication of NO932636D0 publication Critical patent/NO932636D0/en

1994-01-24 Publication of NO932636L publication Critical patent/NO932636L/en

1997-07-21 Publication of NO300772B1 publication Critical patent/NO300772B1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Ophthalmology & Optometry (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

NO932636A 1992-07-22 1993-07-21 Benzimidazoles, drugs containing these compounds, and their use NO300772B1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4224133A DE4224133A1 (en)	1992-07-22	1992-07-22	Benzimidazoles, medicaments containing these compounds and process for their preparation

Publications (3)

Publication Number	Publication Date
NO932636D0 NO932636D0 (en)	1993-07-21
NO932636L true NO932636L (en)	1994-01-24
NO300772B1 NO300772B1 (en)	1997-07-21

Family

ID=6463804

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO932636A NO300772B1 (en)	1992-07-22	1993-07-21	Benzimidazoles, drugs containing these compounds, and their use

Country Status (20)

Country	Link
EP (1)	EP0581166A1 (en)
JP (1)	JPH06179659A (en)
KR (1)	KR940005584A (en)
CN (1)	CN1050122C (en)
AU (1)	AU675433B2 (en)
CA (1)	CA2100927A1 (en)
CZ (1)	CZ144993A3 (en)
DE (1)	DE4224133A1 (en)
FI (1)	FI933284A7 (en)
HU (1)	HUT64955A (en)
IL (1)	IL106408A (en)
MX (1)	MX9304424A (en)
NO (1)	NO300772B1 (en)
NZ (1)	NZ248217A (en)
PL (1)	PL172929B1 (en)
RU (1)	RU2126401C1 (en)
SG (1)	SG43083A1 (en)
SK (1)	SK73293A3 (en)
TW (1)	TW229207B (en)
ZA (1)	ZA93529B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4233590A1 (en) *	1992-10-06	1994-04-07	Thomae Gmbh Dr K	Benzimidazoles, medicaments containing these compounds and process for their preparation
DE4304455A1 (en) *	1993-02-15	1994-08-18	Bayer Ag	Heterocyclic substituted phenyl-cyclohexane-carboxylic acid derivatives
DE4324580A1 (en) *	1993-07-22	1995-01-26	Thomae Gmbh Dr K	Bicyclic heterocycles, pharmaceutical compositions containing them and methods for their preparation
DE19503160A1 (en) *	1995-02-01	1996-08-08	Bayer Ag	Use of phenylcyclohexylcarboxylic acid amides
EA002357B1 (en) *	1995-12-28	2002-04-25	Фудзисава Фармасьютикал Ко., Лтд.	Benzimidazole derivatives
TW453999B (en) *	1997-06-27	2001-09-11	Fujisawa Pharmaceutical Co	Benzimidazole derivatives
RU2185171C2 (en) *	1999-06-25	2002-07-20	Институт нефтехимии и катализа АН РБ и УНЦ РАН	Method for prophylaxis of reocclusions in case of operations conducted upon the main vessels
HU222773B1 (en) *	2000-04-21	2003-10-28	Richter Gedeon Vegyészeti Gyár Rt.	Process for producing a known tetrazole derivative
JPWO2005011736A1 (en) *	2003-07-30	2006-09-14	株式会社東北テクノアーチ	Preventive and / or therapeutic agent for Alzheimer's disease
DE102004060699A1 (en) *	2004-12-16	2006-06-22	Ratiopharm Gmbh	Process for the preparation of candesartan
RU2427574C2 (en) *	2009-07-16	2011-08-27	Государственное образовательное учреждение высшего профессионального образования "Астраханский государственный университет" (АГУ)	Monohydrochlorides and sodium salts of tautomeric 5 (6)-alkoxycarbonylamino-derivatives of 2-aryl-1-hydroxybenzimidazole-3-oxide with high antifungal activity and synthesis method thereof
CN101891735B (en) *	2009-11-25	2012-07-18	北京理工大学	Biphenyl sulfafurazole compound, synthesis method and application thereof
CN101921265B (en) *	2009-11-25	2012-07-04	北京理工大学	Biphenylacylamine tetrazole compounds, synthetic method and application
ES2552514T3 (en) *	2011-11-03	2015-11-30	Hoffmann-La Roche Ag	Bicyclic Piperazine Compounds
CN105820125B (en) *	2015-01-09	2018-12-07	北京中医药大学	A kind of compound and its preparation method and application for treating hypertension
CN105384729B (en) *	2015-07-09	2019-02-19	天津青松华药医药有限公司	Telmisartan ester derivative and the preparation method and application thereof
CN106749220B (en) *	2017-01-18	2019-08-06	东华大学	A kind of 6'-substituted benzimidazole-4-substituted methyl indole derivative and its preparation and application

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3928177A1 (en) *	1989-04-08	1991-02-28	Thomae Gmbh Dr K	BENZIMIDAZOLE, MEDICAMENTS CONTAINING THESE COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
CA2075627A1 (en) *	1990-02-13	1991-08-14	William J. Greenlee	Angiotensin ii antagonists incorporating a substituted benzyl element
RU1836357C (en) *	1990-07-23	1993-08-23	Др.Карл Томэ ГмбХ	Benzimidazole derivatives, their isomers, mixtures of isomers, hydrates or their physiologically bearable salts possessing properties antagonistic to angiotenzine
SI9210098B (en) *	1991-02-06	2000-06-30	Dr. Karl Thomae	Benzimidazoles, drugs with this compounds, and process for their preparation
DE4237656A1 (en) *	1992-06-13	1993-12-16	Merck Patent Gmbh	benzimidazole derivatives

1992
- 1992-07-22 DE DE4224133A patent/DE4224133A1/en not_active Withdrawn
1993
- 1993-06-12 TW TW082104675A patent/TW229207B/zh active
- 1993-07-12 SK SK732-93A patent/SK73293A3/en unknown
- 1993-07-20 CN CN93108085A patent/CN1050122C/en not_active Expired - Fee Related
- 1993-07-20 CA CA002100927A patent/CA2100927A1/en not_active Abandoned
- 1993-07-20 EP EP93111581A patent/EP0581166A1/en not_active Ceased
- 1993-07-20 CZ CZ931449A patent/CZ144993A3/en unknown
- 1993-07-20 SG SG1996003403A patent/SG43083A1/en unknown
- 1993-07-20 IL IL10640893A patent/IL106408A/en not_active IP Right Cessation
- 1993-07-21 KR KR1019930013764A patent/KR940005584A/en not_active Ceased
- 1993-07-21 NO NO932636A patent/NO300772B1/en not_active IP Right Cessation
- 1993-07-21 ZA ZA93529A patent/ZA93529B/en unknown
- 1993-07-21 HU HU9302115A patent/HUT64955A/en unknown
- 1993-07-21 PL PL93299754A patent/PL172929B1/en unknown
- 1993-07-21 JP JP5179485A patent/JPH06179659A/en active Pending
- 1993-07-21 AU AU42094/93A patent/AU675433B2/en not_active Expired
- 1993-07-21 FI FI933284A patent/FI933284A7/en unknown
- 1993-07-21 NZ NZ248217A patent/NZ248217A/en unknown
- 1993-07-22 RU RU93049407A patent/RU2126401C1/en active
- 1993-07-22 MX MX9304424A patent/MX9304424A/en unknown

Also Published As

Publication number	Publication date
AU675433B2 (en)	1997-02-06
SG43083A1 (en)	1997-10-17
AU4209493A (en)	1994-01-27
DE4224133A1 (en)	1994-01-27
HU9302115D0 (en)	1993-10-28
EP0581166A1 (en)	1994-02-02
CN1050122C (en)	2000-03-08
NO932636D0 (en)	1993-07-21
CA2100927A1 (en)	1994-01-23
TW229207B (en)	1994-09-01
PL299754A1 (en)	1994-03-21
MX9304424A (en)	1994-01-31
FI933284A7 (en)	1994-01-23
FI933284A0 (en)	1993-07-21
SK73293A3 (en)	1994-04-06
IL106408A (en)	1998-08-16
PL172929B1 (en)	1997-12-31
KR940005584A (en)	1994-03-21
CN1083812A (en)	1994-03-16
CZ144993A3 (en)	1994-03-16
IL106408A0 (en)	1993-11-15
HUT64955A (en)	1994-03-28
NZ248217A (en)	1996-06-25
ZA93529B (en)	1995-01-23
NO300772B1 (en)	1997-07-21
JPH06179659A (en)	1994-06-28
RU2126401C1 (en)	1999-02-20

Publication	Publication Date	Title
DK0502314T3 (en)	1999-03-29	Benzimidazoles, drugs containing these compounds and methods for their preparation
NO924027D0 (en)	1992-10-16	Heterobia Age Derivatives, Drugs Containing These Compounds, and Procedures for Their Preparation
DK0612741T3 (en)	1999-03-29	Cyclic derivatives, drugs containing these compounds and processes for their preparation
NO933248D0 (en)	1993-09-10	Cyclic urea derivatives, drugs containing these compounds, and processes for their preparation
NO930517D0 (en)	1993-02-12	BENZIMIDAZOLYL DERIVATIVES, PHARMACEUTICALS CONTAINING THESE, AND PROCEDURES FOR THEIR PREPARATION
FI954105A7 (en)	1995-09-01	New 4-aminopyridines, their preparation method and drugs containing these compounds
NO922940D0 (en)	1992-07-24	FIVE-JOINT HETEROCYCLIC COMPOUNDS, PROCEDURES FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM
NO934501D0 (en)	1993-12-09	Carboxylic acid derivatives, drugs containing these compounds, and processes for their preparation
NO932120D0 (en)	1993-06-10	BIFENYL DERIVATIVES, PHARMACEUTICALS CONTAINING THESE, AND PROCEDURE FOR THEIR PREPARATION
NO307707B1 (en)	2000-05-15	Spiroazabicyclic compounds, pharmaceutical preparations containing such compounds and their use
NO985368D0 (en)	1998-11-18	Substituted imidazolidine derivatives, their preparation, their use and pharmaceutical preparations containing the compounds
NO932636L (en)	1994-01-24	Benzimidazoles, drugs containing these compounds, and methods for their preparation
DK610284A (en)	1985-06-29	2-PHENYL IMIDAZOLD DERIVATIVES, THEIR PREPARATIONS AND MEDICINES CONTAINING THESE COMPOUNDS
DK162491D0 (en)	1991-09-20	Heterocyclic compounds, their preparation and pharmaceutical preparations containing the compounds
DK435588A (en)	1989-02-08	ARALKYLAMINOAL COXYPHENYL DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND MENTALS CONTAINING THESE
DK166279C (en)	1993-08-23	3,4-DIHYDRO-2H-BENZOOEBAAPYRANDER DERIVATIVES, THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS
DK0838469T3 (en)	2002-03-18	10,13,15-Trioxatricyclo (9.2.1 9.6) -pentadecanone derivatives, process for their preparation, and drugs containing these compounds
NO931342D0 (en)	1993-04-07	BENZIMIDAZOLES, MEDICAL PREPARATIONS CONTAINING THESE, AND PROCEDURES FOR THEIR PREPARATION
DK155292D0 (en)	1992-12-23	CHEMICAL COMPOUNDS, THEIR PREPARATION AND USE
NO930796D0 (en)	1993-03-04	GLYCOPEPTY DERIVATIVES, PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL AGENTS CONTAINING THESE
DK102990A (en)	1990-11-14	THIENO-TRIAZOLODIAZEPINE DERIVATIVES, PROCEDURES FOR THE PREPARATION OF SUCH COMPOUNDS, AND MEDICINES CONTAINING THESE
DK304090D0 (en)	1990-12-21	GLYCEROLD DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND THERAPEUTIC PREPARATIONS CONTAINING THESE
NO940130D0 (en)	1994-01-14	Benzimidazole derivatives, methods for their preparation and the therapeutic use thereof
NO933558D0 (en)	1993-10-05	BENZIMIDAZOLES, PHARMACEUTICALS CONTAINING THESE COMPOUNDS, AND PROCEDURE FOR THEIR PREPARATION
NO308213B1 (en)	2000-08-14	Substituted indanylidinacetylguanidines, their use and drugs containing the compounds

Legal Events

Date	Code	Title	Description
2001-03-05	MM1K	Lapsed by not paying the annual fees	Free format text: LAPSED IN JANUARY 2001