NO930829L - Fremgangsmaate for fremstilling av klavulansyresalter - Google Patents
Fremgangsmaate for fremstilling av klavulansyresalterInfo
- Publication number
- NO930829L NO930829L NO93930829A NO930829A NO930829L NO 930829 L NO930829 L NO 930829L NO 93930829 A NO93930829 A NO 93930829A NO 930829 A NO930829 A NO 930829A NO 930829 L NO930829 L NO 930829L
- Authority
- NO
- Norway
- Prior art keywords
- procedure
- preparation
- acid salts
- clavulanic acid
- clavulanic
- Prior art date
Links
- HZZVJAQRINQKSD-PBFISZAISA-N clavulanic acid Chemical class OC(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 HZZVJAQRINQKSD-PBFISZAISA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0047292A AT400033B (de) | 1992-03-10 | 1992-03-10 | Neues verfahren zur isolierung und reinigung von clavulansäure und zur herstellung von pharmakologisch verträglichen salzen derselben |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO930829D0 NO930829D0 (no) | 1993-03-08 |
| NO930829L true NO930829L (no) | 1993-09-13 |
| NO301372B1 NO301372B1 (no) | 1997-10-20 |
Family
ID=3491521
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO930829A NO301372B1 (no) | 1992-03-10 | 1993-03-08 | Fremgangsmåte for fremstilling av et farmasöytisk tålbart salt av klavulansyre |
Country Status (21)
| Country | Link |
|---|---|
| US (4) | US20010036940A1 (no) |
| JP (2) | JP2817563B2 (no) |
| CN (3) | CN1045604C (no) |
| AT (1) | AT400033B (no) |
| AU (1) | AU659282B2 (no) |
| CH (1) | CH685054A5 (no) |
| CY (1) | CY1995A (no) |
| DE (1) | DE4307422B4 (no) |
| DK (1) | DK26093A (no) |
| ES (1) | ES2058029B1 (no) |
| FI (1) | FI101965B (no) |
| FR (1) | FR2688506B1 (no) |
| GB (1) | GB2264944B (no) |
| GR (1) | GR1002329B (no) |
| HK (1) | HK42696A (no) |
| IE (1) | IE70926B1 (no) |
| IT (1) | IT1261213B (no) |
| NL (1) | NL9300430A (no) |
| NO (1) | NO301372B1 (no) |
| SE (1) | SE508043C2 (no) |
| TW (1) | TW364907B (no) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT399155B (de) * | 1992-03-26 | 1995-03-27 | Lek Tovarna Farmacevtskih | Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung |
| SI9300296B (sl) * | 1992-06-11 | 1998-06-30 | Smithkline Beecham P.L.C. | Postopek in intermedianti za pripravo klavulanske kisline |
| KR100200239B1 (ko) * | 1992-10-21 | 1999-06-15 | 김충환 | 클라불란산 칼륨염의 제조방법 |
| DE69427312T2 (de) | 1993-11-17 | 2001-08-23 | Biochemie Ges.M.B.H., Kundl | Trennung von Cephalosporinisomeren |
| GB9426261D0 (en) | 1994-12-24 | 1995-02-22 | Spurcourt Ltd | Clavulanic acid salts |
| JPH11501023A (ja) * | 1995-02-25 | 1999-01-26 | スパーコート リミテッド | クラブラン酸塩 |
| KR100200242B1 (ko) * | 1995-05-16 | 1999-06-15 | 김충환 | 클라불란산염의 제조 방법 |
| AT403375B (de) * | 1995-11-15 | 1998-01-26 | Biochemie Gmbh | Verfahren zur fällung von alkalisalzen der clavulansäure |
| WO2000004028A1 (en) * | 1998-07-16 | 2000-01-27 | Dsm N.V. | Improved process for the preparation of salts and esters of clavulanic acid |
| SI1165049T2 (sl) * | 1999-04-01 | 2011-11-30 | Dsm Ip Assets Bv | Aglomerati s kristalizacijo |
| HU228593B1 (en) * | 2000-05-13 | 2013-04-29 | Smithkline Beecham Plc | Process for the purification of a salt of clavulanic acid |
| KR101772375B1 (ko) * | 2005-09-07 | 2017-08-29 | 신라젠(주) | Gm-csf를 발현하는 폭스바이러스를 사용한 전이성 및/또는 전신 파종성 암의 전신 치료법 |
| JP7028064B2 (ja) | 2018-05-30 | 2022-03-02 | 横河電機株式会社 | 機器保全装置、機器保全方法、機器保全プログラム及び記録媒体 |
| KR20230038222A (ko) | 2020-07-10 | 2023-03-17 | 카본 클린 솔루션스 리미티드 | 저급 열을 사용하여 용매에서 이산화탄소를 제거하는 방법 및 시스템 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3288800A (en) | 1962-05-29 | 1966-11-29 | Squibb & Sons Inc | Schiff's bases of 6-amino-penicillanic acid and purification of 6-aminopenicillanic acid by the use thereof |
| GB1508977A (en) | 1974-04-20 | 1978-04-26 | Beecham Group Ltd | Beta-lactam antibiotic from streptomyces clavuligerus |
| NZ177159A (en) | 1974-04-20 | 1978-03-06 | Beecham Group Ltd | Clavulanic acid, salts, esters and preparation thereof from streptomyces clavuligerus: pharmaceutical compositions |
| US4110165A (en) | 1974-04-20 | 1978-08-29 | Beecham Group Limited | Process for the production of clavulanic acid |
| US4144242A (en) | 1975-02-07 | 1979-03-13 | Glaxo Laboratories Limited | Process for the purification of clavulanic acid |
| GB1543563A (en) | 1975-02-07 | 1979-04-04 | Glaxo Lab Ltd | Beta-lactam antibiotic in purified form |
| GB1561395A (en) | 1976-02-26 | 1980-02-20 | Beecham Group Ltd | -lactam antibiotic |
| GB1578739A (en) * | 1976-07-23 | 1980-11-05 | Beecham Group Ltd | Amine salts of clavulanic acid methods for their preparation and compositions containing them |
| GB2003863B (en) | 1977-09-01 | 1982-03-31 | Beecham Group Ltd | Chemical process |
| EP0002312B1 (en) | 1977-11-26 | 1982-02-03 | Beecham Group Plc | Derivatives of clavulanic acid and pharmaceutical compositions containing them |
| BE862211A (fr) * | 1977-12-22 | 1978-06-22 | Beecham Group Ltd | Agents antibacteriens |
| US4454069A (en) | 1979-08-24 | 1984-06-12 | Beecham Group Limited | Clavulanic acid salts and their preparation from the tertiary butyl amine salt |
| DE3063683D1 (en) * | 1979-08-24 | 1983-07-14 | Beecham Group Plc | Amine salt of clavulanic acid, its preparation and use |
| AR245221A1 (es) | 1984-10-27 | 1993-12-30 | Beecham Group Plc | Un metodo para la produccion de acido clavulanico por fermentacion de s. clavuligerus |
| GB8618888D0 (en) | 1986-08-01 | 1986-09-10 | Davy Mckee Ltd | Process |
| DK175709B1 (da) | 1987-01-29 | 2005-01-31 | Beecham Group Plc | Fremgangsmåde til fremstilling af kalium-clavulanat |
| US5679789A (en) | 1987-01-29 | 1997-10-21 | Beecham Group, P.L.C. | Pharmaceutical compositions comprising potassium clavulanate and methods of using them |
| ES2010143A6 (es) * | 1989-03-01 | 1989-10-16 | Pharma Mar S A Pharmar | Un nuevo procedimiento de obtencion del acido z(2r,5r)-3-(2-hiadroxietiliden)-7- oxo-4-oxa-1-azabiciclo(3,2,0) -heptano-2-carboxilico y de sales estares farmaceutiacamente aceptables del mismo,a partir de caldos de fermentacion de streptomyces, sp. |
| US5210296A (en) | 1990-11-19 | 1993-05-11 | E. I. Du Pont De Nemours And Company | Recovery of lactate esters and lactic acid from fermentation broth |
| AT399155B (de) | 1992-03-26 | 1995-03-27 | Lek Tovarna Farmacevtskih | Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung |
| SI9300296B (sl) | 1992-06-11 | 1998-06-30 | Smithkline Beecham P.L.C. | Postopek in intermedianti za pripravo klavulanske kisline |
| SI9200139A (en) | 1992-07-08 | 1994-03-31 | Lek Tovarna Farmacevtskih | New inclusion complex of clavulanic acid with hydrophylyc and hydropholyc beta-cyclodextrin derivates for production of them |
| KR100200239B1 (ko) | 1992-10-21 | 1999-06-15 | 김충환 | 클라불란산 칼륨염의 제조방법 |
| GB9401969D0 (en) | 1994-02-02 | 1994-03-30 | Smithkline Beecham Plc | Process |
| SI9400107A (en) | 1994-03-02 | 1995-10-31 | Lek Tovarna Farmacevtskih | New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804. |
| JPH11501023A (ja) | 1995-02-25 | 1999-01-26 | スパーコート リミテッド | クラブラン酸塩 |
| GB2298201B (en) | 1995-02-25 | 1997-05-28 | Spurcourt Ltd | Clavulanic acid salts |
| SI9500074A (en) | 1995-03-10 | 1996-10-31 | Lek Tovarna Farmacevtskih | Process for preparation of alkani salts of clavulanic acid. |
| SI9500134B (sl) | 1995-04-20 | 2004-04-30 | Lek, | Postopek za pripravo čistih alkalijskih soli klavulanske kisline |
| KR100200242B1 (ko) | 1995-05-16 | 1999-06-15 | 김충환 | 클라불란산염의 제조 방법 |
| GB9515809D0 (en) | 1995-08-02 | 1995-10-04 | Smithkline Beecham Plc | Process |
| SI9500265A1 (en) | 1995-08-28 | 1997-02-28 | Lek Tovarna Farmacevtskih | Process for purification of the aqueous fermented broth filtrate of streptomyces sp. p 6621 ferm p 2804 by ultrafiltration |
| ZA975198B (en) | 1996-06-13 | 1997-12-15 | Smithkline Beecham Corp | Improved process for preparing potassium clavulanate. |
| AU5551698A (en) | 1996-11-11 | 1998-06-03 | Gist-Brocades B.V. | Process for the preparation of salts and esters of clavulanic acid |
-
1992
- 1992-03-10 AT AT0047292A patent/AT400033B/de not_active IP Right Cessation
-
1993
- 1993-03-05 CH CH670/93A patent/CH685054A5/de not_active IP Right Cessation
- 1993-03-08 JP JP5046691A patent/JP2817563B2/ja not_active Expired - Fee Related
- 1993-03-08 SE SE9300758A patent/SE508043C2/sv not_active IP Right Cessation
- 1993-03-08 GB GB9304704A patent/GB2264944B/en not_active Expired - Fee Related
- 1993-03-08 NO NO930829A patent/NO301372B1/no unknown
- 1993-03-09 IE IE930172A patent/IE70926B1/en not_active IP Right Cessation
- 1993-03-09 AU AU34070/93A patent/AU659282B2/en not_active Ceased
- 1993-03-09 FR FR9302720A patent/FR2688506B1/fr not_active Expired - Fee Related
- 1993-03-09 FI FI931032A patent/FI101965B/fi active
- 1993-03-09 CN CN93102897A patent/CN1045604C/zh not_active Expired - Fee Related
- 1993-03-09 DE DE4307422A patent/DE4307422B4/de not_active Expired - Fee Related
- 1993-03-09 DK DK026093A patent/DK26093A/da not_active Application Discontinuation
- 1993-03-09 GR GR930100090A patent/GR1002329B/el not_active IP Right Cessation
- 1993-03-10 NL NL9300430A patent/NL9300430A/nl active Search and Examination
- 1993-03-10 IT ITRM930147A patent/IT1261213B/it active IP Right Grant
- 1993-03-10 ES ES09300483A patent/ES2058029B1/es not_active Expired - Fee Related
- 1993-05-04 TW TW082103491A patent/TW364907B/zh not_active IP Right Cessation
-
1996
- 1996-03-14 HK HK42696A patent/HK42696A/xx not_active IP Right Cessation
- 1996-06-29 CN CN96108278A patent/CN1150153A/zh active Pending
- 1996-06-29 CN CN96108276A patent/CN1145906A/zh active Pending
-
1997
- 1997-08-13 JP JP9218732A patent/JPH1067785A/ja active Pending
- 1997-09-05 CY CY199597A patent/CY1995A/en unknown
-
2001
- 2001-06-26 US US09/892,179 patent/US20010036940A1/en not_active Abandoned
-
2002
- 2002-02-08 US US10/071,364 patent/US20020072513A1/en not_active Abandoned
- 2002-09-20 US US10/251,948 patent/US20030022882A1/en not_active Abandoned
-
2003
- 2003-05-13 US US10/437,097 patent/USH2158H1/en not_active Abandoned
Also Published As
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