NO880833L - Nye substituerte benzoderivater. - Google Patents
Nye substituerte benzoderivater.Info
- Publication number
- NO880833L NO880833L NO880833A NO880833A NO880833L NO 880833 L NO880833 L NO 880833L NO 880833 A NO880833 A NO 880833A NO 880833 A NO880833 A NO 880833A NO 880833 L NO880833 L NO 880833L
- Authority
- NO
- Norway
- Prior art keywords
- derivatives
- benzode
- formula
- new substituted
- receptors
- Prior art date
Links
- 210000003169 central nervous system Anatomy 0.000 abstract 2
- 230000003518 presynaptic effect Effects 0.000 abstract 2
- -1 1-aminomethyl Chemical class 0.000 abstract 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- PQNFLJBBNBOBRQ-UHFFFAOYSA-N indane Chemical compound C1=CC=C2CCCC2=C1 PQNFLJBBNBOBRQ-UHFFFAOYSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 230000001242 postsynaptic effect Effects 0.000 abstract 1
- 201000000980 schizophrenia Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878704572A GB8704572D0 (en) | 1987-02-26 | 1987-02-26 | Organic compounds |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO880833D0 NO880833D0 (no) | 1988-02-25 |
| NO880833L true NO880833L (no) | 1988-08-29 |
| NO169119B NO169119B (no) | 1992-02-03 |
| NO169119C NO169119C (no) | 1992-05-13 |
Family
ID=10613009
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO880833A NO169119C (no) | 1987-02-26 | 1988-02-25 | Analogifremgangsmaate ved fremstilling av indan-, dihydrobenzofuran- og dihydrobenzotiofen-derivater |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US4847254A (no) |
| EP (1) | EP0281261B1 (no) |
| JP (1) | JP2677588B2 (no) |
| AT (1) | ATE75723T1 (no) |
| AU (1) | AU608293B2 (no) |
| CA (1) | CA1338934C (no) |
| DE (1) | DE3870666D1 (no) |
| DK (1) | DK170636B1 (no) |
| ES (1) | ES2037208T3 (no) |
| FI (1) | FI97380C (no) |
| GB (1) | GB8704572D0 (no) |
| GR (1) | GR3004984T3 (no) |
| IE (1) | IE61257B1 (no) |
| IL (1) | IL85342A (no) |
| NO (1) | NO169119C (no) |
| NZ (1) | NZ223440A (no) |
| PT (1) | PT86836B (no) |
| ZA (1) | ZA881217B (no) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2059570T3 (es) * | 1988-01-15 | 1994-11-16 | Abbott Lab | 1-aminometil-1,2,3,4-tetrahidronaftalenos e -indanos. |
| JP2931986B2 (ja) * | 1989-02-17 | 1999-08-09 | 武田薬品工業株式会社 | アラルキルアミン誘導体 |
| ES2071074T3 (es) * | 1989-03-22 | 1995-06-16 | Ciba Geigy Ag | Benzotiopiranilaminas. |
| JPH0318935A (ja) * | 1989-06-15 | 1991-01-28 | Hitachi Ltd | データリストに対するアクセスの直列化方式 |
| US5500444A (en) * | 1989-11-14 | 1996-03-19 | Hoechst Marion Roussel, Inc. | Cardioprotective tocopherol analogs |
| IE68675B1 (en) * | 1990-11-01 | 1996-07-10 | Takeda Chemical Industries Ltd | Aminocoumaran derivatives their production and use |
| US5643784A (en) * | 1990-12-04 | 1997-07-01 | H, Lundbeck A/S | Indan derivatives |
| DK36291D0 (da) * | 1991-03-01 | 1991-03-01 | Lundbeck & Co As H | Anvendelse af piperidylsubstituerede indolderivater til behandling af kognitive lidelser |
| NZ243065A (en) * | 1991-06-13 | 1995-07-26 | Lundbeck & Co As H | Piperidine derivatives and pharmaceutical compositions |
| EP0550292A1 (en) * | 1992-01-02 | 1993-07-07 | Merrell Dow Pharmaceuticals Inc. | Tissue protective tocopherol analogs |
| ATE158287T1 (de) * | 1992-04-06 | 1997-10-15 | Merrell Pharma Inc | Derivate von 2,3-dihydro-2,2,4,6,7-pentaalkyl-5- benzofuranen |
| US5721233A (en) * | 1992-04-06 | 1998-02-24 | Merrell Pharmaceuticals Inc. | Derivatives of 2,3-dihydro benzofuranols |
| US5510373A (en) * | 1992-04-06 | 1996-04-23 | Merrell Pharmaceuticals Inc. | Cardioprotective agents |
| US5545660A (en) * | 1992-04-07 | 1996-08-13 | Merrell Pharmaceuticals Inc. | Hydrazide derivatives of 3,4-dihydro-2H-1-benzopyrans |
| DK55192D0 (da) * | 1992-04-28 | 1992-04-28 | Lundbeck & Co As H | 1-piperazino-1,2-dihydroindenderivater |
| DK78692D0 (da) * | 1992-06-12 | 1992-06-12 | Lundbeck & Co As H | Dimere piperidin- og piperazinderivater |
| DK148292D0 (da) * | 1992-12-09 | 1992-12-09 | Lundbeck & Co As H | Forbindelser |
| ES2144508T3 (es) * | 1993-01-12 | 2000-06-16 | Asahi Chemical Ind | Derivados de 2,3-dihidrobenzofurano. |
| US5792791A (en) * | 1993-01-12 | 1998-08-11 | Asahi Kasei Kogyo Kabushiki Kaisha | 2,3-dihydrobenzofuran derivatives |
| CA2176127A1 (en) * | 1993-12-21 | 1995-06-29 | William Henry Walker Lunn | Methods for the treatment or prevention of conditions associated with amyloidogenic reptides |
| AU694212B2 (en) * | 1994-04-28 | 1998-07-16 | Merck Sharp & Dohme Limited | Benzofuran derivatives as d4 receptor antagonists |
| US5798382A (en) * | 1994-07-07 | 1998-08-25 | Asahi Kasei Kogyo Kabushiki Kaisha | 2,3-dihydrobenzofuran derivatives, method for producing the same, and use thereof |
| JPH09124643A (ja) * | 1995-08-14 | 1997-05-13 | Bristol Myers Squibb Co | 抗うつ作用を有する１−アリールアルキル−４−（アルコキシピリジニル）−又は４−（アルコキシピリミジニル）ピペラジン誘導体 |
| GB9521347D0 (en) * | 1995-10-18 | 1995-12-20 | Merck Sharp & Dohme | Therapeutic agents |
| AU4652697A (en) * | 1996-10-08 | 1998-05-05 | Eli Lilly And Company | New serotonin 5-ht1f agonists |
| US7008950B1 (en) | 1997-06-05 | 2006-03-07 | Takeda Chemical Industries, Ltd. | Benzofurans as suppressors of neurodegeneration |
| EP1303502A2 (en) * | 2000-07-06 | 2003-04-23 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Tetrahydrobenzothiazole analogues as neuroprotective agents |
| TWI320783B (en) | 2005-04-14 | 2010-02-21 | Otsuka Pharma Co Ltd | Heterocyclic compound |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE623403A (no) * | 1962-08-08 | |||
| US3553093A (en) * | 1965-03-19 | 1971-01-05 | Xerox Corp | Color photoelectrophoretic imaging process |
| US3513239A (en) * | 1967-03-15 | 1970-05-19 | Smithkline Corp | Pharmaceutical compositions containing 2-aminoalkyl coumaran derivatives and methods of treating depression therewith |
| BE786748A (fr) * | 1971-07-26 | 1973-01-26 | Basf Ag | 1-aminomethyl-indanes-n-substitues |
| CH601166A5 (no) * | 1974-02-14 | 1978-06-30 | Ciba Geigy Ag | |
| JPS535146A (en) * | 1976-07-02 | 1978-01-18 | Tanabe Seiyaku Co Ltd | Indane derivatives and their preparation |
| US4505932A (en) * | 1983-05-13 | 1985-03-19 | Abbott Laboratories | Method of producing α2 -adrenergic receptor agonist activity |
| US4777168A (en) * | 1984-10-23 | 1988-10-11 | Rorer Pharmaceutical Corporation | Bicyclic benzo-oxy heterocyclic ethers and thioethers, pharmaceutical compositions and use |
-
1987
- 1987-02-26 GB GB878704572A patent/GB8704572D0/en active Pending
-
1988
- 1988-02-03 IE IE29788A patent/IE61257B1/en not_active IP Right Cessation
- 1988-02-07 IL IL85342A patent/IL85342A/xx not_active IP Right Cessation
- 1988-02-08 NZ NZ223440A patent/NZ223440A/xx unknown
- 1988-02-09 ES ES198888301073T patent/ES2037208T3/es not_active Expired - Lifetime
- 1988-02-09 EP EP88301073A patent/EP0281261B1/en not_active Expired - Lifetime
- 1988-02-09 DE DE8888301073T patent/DE3870666D1/de not_active Expired - Lifetime
- 1988-02-09 AT AT88301073T patent/ATE75723T1/de not_active IP Right Cessation
- 1988-02-12 US US07/155,354 patent/US4847254A/en not_active Expired - Fee Related
- 1988-02-22 ZA ZA881217A patent/ZA881217B/xx unknown
- 1988-02-23 CA CA000559562A patent/CA1338934C/en not_active Expired - Fee Related
- 1988-02-23 DK DK091488A patent/DK170636B1/da not_active IP Right Cessation
- 1988-02-25 PT PT86836A patent/PT86836B/pt not_active IP Right Cessation
- 1988-02-25 NO NO880833A patent/NO169119C/no unknown
- 1988-02-25 AU AU12167/88A patent/AU608293B2/en not_active Ceased
- 1988-02-26 FI FI880906A patent/FI97380C/fi not_active IP Right Cessation
- 1988-02-26 JP JP63042388A patent/JP2677588B2/ja not_active Expired - Lifetime
-
1989
- 1989-01-18 US US07/298,630 patent/US4946863A/en not_active Expired - Fee Related
-
1992
- 1992-06-18 GR GR920401319T patent/GR3004984T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE3870666D1 (de) | 1992-06-11 |
| EP0281261A3 (en) | 1989-11-23 |
| AU1216788A (en) | 1988-09-01 |
| GR3004984T3 (no) | 1993-04-28 |
| US4847254A (en) | 1989-07-11 |
| IE61257B1 (en) | 1994-10-19 |
| NO169119C (no) | 1992-05-13 |
| US4946863A (en) | 1990-08-07 |
| PT86836B (pt) | 1992-05-29 |
| AU608293B2 (en) | 1991-03-28 |
| JPS63264557A (ja) | 1988-11-01 |
| NO169119B (no) | 1992-02-03 |
| FI97380C (fi) | 1996-12-10 |
| DK91488D0 (da) | 1988-02-23 |
| EP0281261A2 (en) | 1988-09-07 |
| JP2677588B2 (ja) | 1997-11-17 |
| ATE75723T1 (de) | 1992-05-15 |
| EP0281261B1 (en) | 1992-05-06 |
| ES2037208T3 (es) | 1993-06-16 |
| ZA881217B (en) | 1989-01-25 |
| IE880297L (en) | 1988-08-26 |
| DK91488A (da) | 1988-08-27 |
| IL85342A (en) | 1993-01-14 |
| PT86836A (pt) | 1988-03-01 |
| NZ223440A (en) | 1991-02-26 |
| DK170636B1 (da) | 1995-11-20 |
| FI880906A7 (fi) | 1988-08-27 |
| NO880833D0 (no) | 1988-02-25 |
| CA1338934C (en) | 1997-02-25 |
| FI880906A0 (fi) | 1988-02-26 |
| FI97380B (fi) | 1996-08-30 |
| GB8704572D0 (en) | 1987-04-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO880833L (no) | Nye substituerte benzoderivater. | |
| PT88255A (pt) | Processo para a preparacao de derivados do indole | |
| PT92728A (pt) | Processo para a preparacao de derivados de piperazinilo e de composicoes farmaceuticas que os contem | |
| ATE210654T1 (de) | Tricyclische amide und harnstoffderivate zur inhibierung der g-protein funktion und für die behandlung von proliferatinen erkrankungen | |
| NO178262C (no) | Analogifremgangsmåte for fremstilling av terapeutisk aktive substituerte cykloheksanoler | |
| PT91417A (pt) | Processo para a preparacao de derivados indolicos | |
| DE68918609D1 (de) | Piperidinoalkyl-Derivate von Carbonsäure-Amiden. | |
| LV10243A (lv) | 8-Aizvietota 2-aminotetralina atvasinajumi to iegusanas panemiens farmaceitiska kompozicija panemiens centralas nervu sistemas traucejumu arstesanai | |
| NO176097C (no) | Analogifremgangsmåte for fremstilling av terapeutisk aktive substituerte cykloheksener | |
| ATE152708T1 (de) | (1,2n) und (3,2n)-karbozyklische-2-amino- tetralinderivate | |
| DK0405442T3 (da) | 4,5-Dihydro-6H-imidazo 4,5,1-ij quinolin-6-on-6-oxim-O-sulfonsyrederivater | |
| HU9401968D0 (en) | Pharmaceutical compositions and process for producing them |