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NO872589D0 - NOEYTRAL METALOENDOPEPTIDASE INHIBITORS FOR TREATMENT OF HYPERTENSION. - Google Patents

NOEYTRAL METALOENDOPEPTIDASE INHIBITORS FOR TREATMENT OF HYPERTENSION.

Info

Publication number
NO872589D0
NO872589D0 NO872589A NO872589A NO872589D0 NO 872589 D0 NO872589 D0 NO 872589D0 NO 872589 A NO872589 A NO 872589A NO 872589 A NO872589 A NO 872589A NO 872589 D0 NO872589 D0 NO 872589D0
Authority
NO
Norway
Prior art keywords
noeytral
metaloendopeptidase
hypertension
inhibitors
treatment
Prior art date
Application number
NO872589A
Other languages
Norwegian (no)
Other versions
NO872589L (en
Inventor
Martin F Haslanger
Jr Edmund J Sybertz
Bernard R Neustadt
Elizabeth M Smith
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/876,610 external-priority patent/US4749688A/en
Priority claimed from US07032153 external-priority patent/US4801609B1/en
Application filed by Schering Corp filed Critical Schering Corp
Publication of NO872589D0 publication Critical patent/NO872589D0/en
Publication of NO872589L publication Critical patent/NO872589L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
NO872589A 1986-06-20 1987-06-19 ANALOGY PROCEDURES FOR THE PREPARATION OF INHIBITORS AGAINST NTRAL ME-TALLOENDOPEPTIDASE FOR USE IN THE TREATMENT OF HYPERTENSION. NO872589L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/876,610 US4749688A (en) 1986-06-20 1986-06-20 Use of neutral metalloendopeptidase inhibitors in the treatment of hypertension
US07032153 US4801609B1 (en) 1987-03-27 1987-03-27 Mercapto-acylamino acid antihypertensives

Publications (2)

Publication Number Publication Date
NO872589D0 true NO872589D0 (en) 1987-06-19
NO872589L NO872589L (en) 1987-12-21

Family

ID=26708050

Family Applications (1)

Application Number Title Priority Date Filing Date
NO872589A NO872589L (en) 1986-06-20 1987-06-19 ANALOGY PROCEDURES FOR THE PREPARATION OF INHIBITORS AGAINST NTRAL ME-TALLOENDOPEPTIDASE FOR USE IN THE TREATMENT OF HYPERTENSION.

Country Status (14)

Country Link
US (1) US5061710A (en)
EP (1) EP0254032A3 (en)
JP (3) JP2542620B2 (en)
KR (1) KR940001769B1 (en)
AU (1) AU636423B2 (en)
DK (1) DK313887A (en)
FI (1) FI872720A7 (en)
HU (1) HU208952B (en)
IL (1) IL82908A (en)
MY (1) MY100641A (en)
NO (1) NO872589L (en)
NZ (1) NZ220753A (en)
OA (1) OA08617A (en)
PT (1) PT85124B (en)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262436A (en) * 1987-03-27 1993-11-16 Schering Corporation Acylamino acid antihypertensives in the treatment of congestive heart failure
CA1337400C (en) * 1987-06-08 1995-10-24 Norma G. Delaney Inhibitors of neutral endopeptidase
US5202340A (en) * 1988-05-06 1993-04-13 Ono Pharmaceutical Co., Ltd. Amino acid derivatives
CA1330613C (en) * 1988-05-06 1994-07-05 Masanori Kawamura Amino acid derivatives
AU4211989A (en) * 1988-08-18 1990-03-23 California Biotechnology, Inc. Atrial natriuretic peptide clearance inhibitors
FR2651229B1 (en) * 1989-08-24 1991-12-13 Inst Nat Sante Rech Med NOVEL AMINO ACID DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR THERAPEUTIC APPLICATION.
JPH05501247A (en) * 1989-10-13 1993-03-11 シェリング・コーポレーション Carboxyalkyl dipeptide inhibitors of endopeptidases
FI922867A7 (en) * 1991-06-21 1992-12-22 Tanabe Seiyaku Co DICARBON ACID DERIVATIVES OCH FOERFARANDE FOER FRAMSTAELLNING AV DEM
US5225401A (en) * 1991-08-12 1993-07-06 E. R. Squibb & Sons, Inc. Treatment of congestive heart failure
EP0533084A1 (en) * 1991-09-16 1993-03-24 Schering Corporation Pharmaceutical compositions comprising natriuretic peptides or neutral endopeptidase inhibitors for treating and preventing myointimal proliferation
US5977160A (en) * 1992-04-10 1999-11-02 Brigham And Women's Hospital, Inc. Methods for reducing risk of repeat myocardial infarction and increasing survival in heart attack victims
RU2124503C1 (en) * 1992-05-18 1999-01-10 И.Р.Сквибб энд Санз, Инк. Heterocyclic nitrogen-containing derivatives of carboxylic acid, method of their synthesis, pharmaceutical composition
AU5292193A (en) * 1992-10-02 1994-04-26 Merck & Co., Inc. N-(mercaptoacyl)peptidyl derivatives as antidegenerative agents
US5504080A (en) * 1992-10-28 1996-04-02 Bristol-Myers Squibb Co. Benzo-fused lactams
JPH06199850A (en) * 1992-12-28 1994-07-19 Tanabe Seiyaku Co Ltd Indole-containing peptide and its production
US5508272A (en) * 1993-06-15 1996-04-16 Bristol-Myers Squibb Company Compounds containing a fused bicycle ring and processes therefor
US5362727A (en) * 1993-07-26 1994-11-08 Bristol-Myers Squibb Substituted azepino[2,1-a]isoquinoline compounds
US6037472A (en) * 1993-11-04 2000-03-14 Syntex (U.S.A.) Inc. Matrix metalloprotease inhibitors
US5525723A (en) * 1993-11-18 1996-06-11 Bristol-Myers Squibb Co. Compounds containing a fused multiple ring lactam
US5616775A (en) * 1994-05-05 1997-04-01 Bristol-Myers Squibb Co. Process for preparing homocystein analogs useful as intermediates for compounds containing a fused bicyclic ring
US5587375A (en) * 1995-02-17 1996-12-24 Bristol-Myers Squibb Company Azepinone compounds useful in the inhibition of ACE and NEP
EP0870762B1 (en) * 1995-03-07 2004-04-28 Santen Pharmaceutical Co., Ltd. Novel amino acid derivatives having n,n-dialkylaminophenyl group
US5877313A (en) 1995-05-17 1999-03-02 Bristol-Myers Squibb Benzo-fused azepinone and piperidinone compounds useful in the inhibition of ACE and NEP
US5635504A (en) * 1995-06-07 1997-06-03 Bristol-Myers Squibb Co. Diazepine containing dual action inhibitors
US5650408A (en) * 1995-06-07 1997-07-22 Karanewsky; Donald S. Thiazolo benzazepine containing dual action inhibitors
DE69736189T2 (en) * 1996-09-05 2007-04-26 Santen Pharmaceutical Co., Ltd SULFUR OF AMINO ACID DERIVATIVES
DE19906310A1 (en) * 1999-02-16 2000-08-17 Solvay Pharm Gmbh Use of 3-(1-(2-aralkyl-2-carboxyethyl)-1-cyclopentanecarboxamido)-2,3,4,5-tetrahydro-2-oxo-1H-benz(b)azepine-1-acetic acid derivatives for treating hypertension
JP2005516054A (en) * 2002-01-29 2005-06-02 ワイス Composition and method for modulating connexin hemichannels
US7105539B2 (en) 2002-12-03 2006-09-12 Enobia Pharma Derivatives of succinic and glutaric acids and analogs thereof useful as inhibitors of phex
US7045653B2 (en) 2002-12-23 2006-05-16 Pfizer, Inc. Pharmaceuticals
BRPI0409924A (en) * 2003-04-30 2006-04-25 Inst For Pharm Discovery Inc substituted amino carboxylic acids
WO2005049035A1 (en) * 2003-11-18 2005-06-02 Solvay Pharmaceuticals Gmbh Pharmaceutical compositions for the treatment of renal dysfunction, disease or disorder, in particular in diabetic patients
US7875268B2 (en) 2004-04-06 2011-01-25 L'oreal S.A. Dimercaptoamides, compositions comprising them as reducing agents, and processes for permanently reshaping keratin fibers therewith
AU2005315608B2 (en) 2004-12-15 2011-03-31 Solvay Pharmaceuticals Gmbh Pharmaceutical compositions comprising NEP-inhibitors, inhibitors of the endogenous endothelin producing system and HMG CoA reductase inhibitors
JP5473334B2 (en) 2005-12-23 2014-04-16 ジーランド ファーマ アクティーゼルスカブ Modified lysine mimetic compounds
US20080188545A1 (en) 2006-12-21 2008-08-07 Alimardanov Asaf R Synthesis of pyrrolidine compounds
JP5669729B2 (en) * 2008-05-13 2015-02-12 ジェンメディカ・セラピューティックス・ソシエダッド・リミターダＧｅｎｍｅｄｉｃａ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｓｌ Salicylate conjugates useful for treating metabolic disorders
CA2755069A1 (en) * 2009-03-16 2010-09-23 Genmedica Therapeutics Sl Anti-inflammatory and antioxidant conjugates useful for treating metabolic disorders
CN102421424A (en) * 2009-03-16 2012-04-18 根梅迪卡治疗公司 Combination therapies for treating metabolic disorders
US8993631B2 (en) 2010-11-16 2015-03-31 Novartis Ag Method of treating contrast-induced nephropathy
US8466197B2 (en) 2010-12-14 2013-06-18 Genmedica Therapeutics Sl Thiocarbonates as anti-inflammatory and antioxidant compounds useful for treating metabolic disorders
WO2015100225A1 (en) 2013-12-27 2015-07-02 Novus International Inc. Ethoxylated surfactants
WO2018202865A1 (en) 2017-05-05 2018-11-08 Zealand Pharma A/S Gap junction intercellular communication modulators and their use for the treatment of diabetic eye disease
US10584306B2 (en) 2017-08-11 2020-03-10 Board Of Regents Of The University Of Oklahoma Surfactant microemulsions
CN108191969B (en) * 2018-01-19 2021-01-01 渤海大学 Two ACE-inhibiting peptides derived from Atlantic trout collagen

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US32153A (en) 1861-04-23 Improvement in steam-plows
US4105776A (en) 1976-06-21 1978-08-08 E. R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4053651A (en) * 1976-05-10 1977-10-11 E. R. Squibb & Sons, Inc. Compounds and method for alleviating angiotensin related hypertension
US4228077A (en) * 1976-12-03 1980-10-14 E. R. Squibb & Sons, Inc. N-[2-(mercaptoalkyl)-3-mercaptoalkanoyl]-l-tryptophanes
CH637374A5 (en) * 1977-12-02 1983-07-29 Squibb & Sons Inc Substituted amino acids
IL58849A (en) 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
US4256761A (en) 1979-07-13 1981-03-17 Usv Pharmaceutical Corporation Antihypertensive amides
US4508729A (en) 1979-12-07 1985-04-02 Adir Substituted iminodiacids, their preparation and pharmaceutical compositions containing them
US4350704A (en) * 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
IE52663B1 (en) 1980-04-02 1988-01-20 Warner Lambert Co Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids
GB2074571B (en) * 1980-04-11 1984-02-15 Wellcome Found Alpha-benzyl-substituted amides
FR2480747A1 (en) 1980-04-17 1981-10-23 Roques Bernard AMINO ACID DERIVATIVES AND THEIR THERAPEUTIC APPLICATION
DE3177130D1 (en) 1980-08-30 1990-01-11 Hoechst Ag AMINO ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEANS CONTAINING THEM AND THE USE THEREOF.
US4344949A (en) 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
LU88621I2 (en) 1980-10-23 1995-09-01 Schering Corp Sandopril
US4470972A (en) 1981-04-28 1984-09-11 Schering Corporation 7-Carboxyalkylaminoacyl-1,4-dithia-7-azaspiro[4.4]-nonane-8-carboxylic acids
US4374847A (en) 1980-10-27 1983-02-22 Ciba-Geigy Corporation 1-Carboxyalkanoylindoline-2-carboxylic acids
US4462943A (en) 1980-11-24 1984-07-31 E. R. Squibb & Sons, Inc. Carboxyalkyl amino acid derivatives of various substituted prolines
US4610816A (en) 1980-12-18 1986-09-09 Schering Corporation Substituted dipeptides as inhibitors of enkephalinases
US4820729A (en) 1981-03-30 1989-04-11 Rorer Pharmaceutical Corporation N-substituted-amido-amino acids
US4329495A (en) 1981-05-18 1982-05-11 Pfizer Inc. Enkephalinase enzyme inhibiting compounds
US4401677A (en) * 1981-10-09 1983-08-30 E. R. Squibb & Sons, Inc. Enkephalinase inhibitors
DE3226768A1 (en) 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt DERIVATIVES OF CIS, ENDO-2-AZABICYCLO- (3.3.0) -OCTAN-3-CARBONIC ACID, METHOD FOR THE PRODUCTION THEREOF, THE MEANS CONTAINING THEM AND THE USE THEREOF
DE3271043D1 (en) 1981-11-09 1986-06-12 Merck & Co Inc N-carboxymethyl(amidino)lysyl-proline antihypertensive agents
US4410520A (en) 1981-11-09 1983-10-18 Ciba-Geigy Corporation 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids
FR2518088B1 (en) * 1981-12-16 1987-11-27 Roques Bernard NOVEL AMINO ACID DERIVATIVES AND THEIR THERAPEUTIC APPLICATION
US4555506A (en) * 1981-12-24 1985-11-26 E. R. Squibb & Sons, Inc. Phosphorus containing compounds and use as hypotensives
JPS58140065A (en) * 1982-02-10 1983-08-19 Meito Sangyo Kk Mercaptobenzyl fatty acid derivative and its preparation
GB2128984B (en) 1982-05-12 1985-05-22 Hoffmann La Roche Diaza-bicyclic compounds
US4468519A (en) * 1982-06-14 1984-08-28 E. R. Squibb & Sons, Inc. Esters of phosphinylalkanoyl substituted prolines
US4470973A (en) 1982-07-19 1984-09-11 E. R. Squibb & Sons, Inc. Substituted peptide compounds
DE3243370A1 (en) * 1982-11-24 1984-05-24 Basf Ag, 6700 Ludwigshafen BENZOYLTHIO COMPOUNDS, THEIR PRODUCTION AND USE AS MEDICINAL PRODUCTS
GR81744B (en) 1983-01-28 1984-12-12 Schering Corp
EP0136883B1 (en) * 1983-10-03 1987-11-25 E.R. Squibb & Sons, Inc. Enkephalinase inhibitors
JPS61165362A (en) * 1985-01-18 1986-07-26 Meito Sangyo Kk Mercapto fatty acid derivative and use thereof
US4740499A (en) * 1986-07-28 1988-04-26 Monsanto Company Method of enhancing the bioactivity of atrial peptides
CA1337400C (en) * 1987-06-08 1995-10-24 Norma G. Delaney Inhibitors of neutral endopeptidase

Also Published As

Publication number Publication date
US5061710A (en) 1991-10-29
KR880000103A (en) 1988-03-23
NZ220753A (en) 1992-02-25
AU636423B2 (en) 1993-04-29
PT85124A (en) 1987-07-01
OA08617A (en) 1988-11-30
FI872720L (en) 1987-12-21
IL82908A (en) 1991-09-16
IL82908A0 (en) 1987-12-20
EP0254032A3 (en) 1990-09-05
JPS6339855A (en) 1988-02-20
NO872589L (en) 1987-12-21
AU7445887A (en) 1987-12-24
AU602701B2 (en) 1990-10-25
JP2609443B2 (en) 1997-05-14
JP2542620B2 (en) 1996-10-09
KR940001769B1 (en) 1994-03-05
FI872720A7 (en) 1987-12-21
AU6851790A (en) 1991-07-18
JPH08283153A (en) 1996-10-29
HU208952B (en) 1994-02-28
HUT44940A (en) 1988-05-30
DK313887A (en) 1987-12-21
FI872720A0 (en) 1987-06-18
JPH08176100A (en) 1996-07-09
EP0254032A2 (en) 1988-01-27
PT85124B (en) 1990-08-31
DK313887D0 (en) 1987-06-19
MY100641A (en) 1990-12-29

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