NO822391L - Karbostyrilforbindelser, preparater inneholdende disse og fremgangsmaater for fremstilling av forbindelsene - Google Patents
Karbostyrilforbindelser, preparater inneholdende disse og fremgangsmaater for fremstilling av forbindelseneInfo
- Publication number
- NO822391L NO822391L NO822391A NO822391A NO822391L NO 822391 L NO822391 L NO 822391L NO 822391 A NO822391 A NO 822391A NO 822391 A NO822391 A NO 822391A NO 822391 L NO822391 L NO 822391L
- Authority
- NO
- Norway
- Prior art keywords
- compounds
- carbostyral
- procedures
- preparing
- preparations containing
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 2
- 238000000034 method Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
- C07D215/28—Alcohols; Ethers thereof with halogen atoms or nitro radicals in positions 5, 6 or 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
- C07D215/32—Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP55159016A JPS5782390A (en) | 1980-11-11 | 1980-11-11 | Carbostyril derivative |
| JP55179950A JPS57102888A (en) | 1980-12-18 | 1980-12-18 | Carbostyril derivative |
| PCT/JP1981/000328 WO1982001706A1 (en) | 1980-11-11 | 1981-11-11 | Carbostyril compounds,composition containing same,and process for their preparation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO822391L true NO822391L (no) | 1982-07-09 |
| NO157819B NO157819B (no) | 1988-02-15 |
| NO157819C NO157819C (no) | 1988-05-25 |
Family
ID=26485945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO82822391A NO157819C (no) | 1980-11-11 | 1982-07-09 | Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazo (1,2-a)-pyridin-2-yl-karbostyrilforbindelser. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4414390A (no) |
| EP (1) | EP0052016B1 (no) |
| KR (1) | KR880001657B1 (no) |
| AT (1) | AT382376B (no) |
| AU (1) | AU547586B2 (no) |
| CA (1) | CA1164459A (no) |
| CH (1) | CH653684A5 (no) |
| DE (1) | DE3152512T1 (no) |
| DK (1) | DK157193C (no) |
| ES (1) | ES507545A0 (no) |
| FI (1) | FI71145C (no) |
| IT (1) | IT8149680A0 (no) |
| MX (1) | MX6802E (no) |
| NO (1) | NO157819C (no) |
| PH (1) | PH17158A (no) |
| PT (1) | PT73959B (no) |
| SE (1) | SE440653B (no) |
| SU (1) | SU1215621A3 (no) |
| WO (1) | WO1982001706A1 (no) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4537889A (en) * | 1982-12-27 | 1985-08-27 | Eli Lilly And Company | Inotropic agents |
| US4636502A (en) * | 1982-12-27 | 1987-01-13 | Eli Lilly And Company | Methods of producing a positive inotropic effect or vasodilation by administration of 2-phenyl imidazo pyrimidines and pyrazines |
| GB8305245D0 (en) * | 1983-02-25 | 1983-03-30 | Fujisawa Pharmaceutical Co | Imidazo-heterocyclic compounds |
| US4533734A (en) * | 1983-11-10 | 1985-08-06 | Eli Lilly And Company | Inotropic agents |
| US4710507A (en) * | 1983-12-22 | 1987-12-01 | Pfizer Inc. | Quinolone inotropic agents |
| ES8608874A1 (es) * | 1984-05-29 | 1986-09-01 | Pfizer | Un procedimiento para la preparacion de una 2-(1h)-quinolona |
| US4721721A (en) * | 1984-12-18 | 1988-01-26 | Rorer Pharmaceutical Corporation | 6-(4-thiazole) compounds, cardiotonic compositions including the same, and their uses |
| FR2580646A1 (fr) * | 1985-04-19 | 1986-10-24 | Synthelabo | Derives de 2(1h)-quinolinone, leur preparation et leur application en therapeutique |
| US4666913A (en) * | 1985-11-22 | 1987-05-19 | William H. Rorer, Inc. | Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same, and their uses |
| GB8529362D0 (en) * | 1985-11-28 | 1986-01-02 | Pfizer Ltd | Quinolone cardiac stimulants |
| GB8619902D0 (en) * | 1986-08-15 | 1986-09-24 | Pfizer Ltd | Quinolone cardiac stimulants |
| GB8709448D0 (en) * | 1987-04-21 | 1987-05-28 | Pfizer Ltd | Heterobicyclic quinoline derivatives |
| AU2682695A (en) * | 1994-06-20 | 1996-01-15 | Takeda Chemical Industries Ltd. | Condensed imidazole compounds, their production and use |
| US5552412A (en) * | 1995-01-09 | 1996-09-03 | Pfizer Inc | 5-substitued-6-cyclic-5,6,7,8-tetrahydronaphthalen2-ol compounds which are useful for treating osteoporosis |
| DE10117184A1 (de) * | 2001-04-05 | 2002-10-17 | Gruenenthal Gmbh | Substituierte Imidazol[1,2-a]-pyridin-3-yl-amid- und -aminverbindungen |
| DE10247271A1 (de) * | 2002-10-10 | 2004-08-26 | Grünenthal GmbH | Substituierte C-Imidazo[1,2-a]pyridin-3-yle |
| TWI324151B (en) * | 2003-04-02 | 2010-05-01 | Novartis Ag | Process for the preparation of 5-(haloacetyl)-8-substituted oxy-(1h)-quinolin-2-ones |
| DE102005019181A1 (de) * | 2005-04-25 | 2006-10-26 | Novartis Ag | Peptid-Deformylase (PDF) Inhibitoren 1 |
| CN102216298B (zh) | 2008-09-16 | 2014-04-16 | Csir公司 | 作为hiv-1逆转录酶抑制剂的咪唑并吡啶和咪唑并嘧啶 |
| ES2362894B1 (es) * | 2009-11-16 | 2012-05-21 | Ferrer Internacional S.A. | Procedimiento de preparación del �?cido 4-nitro-oxi-metil-benzoico. |
| EP3280716B1 (de) * | 2015-04-08 | 2020-02-12 | Bayer CropScience AG | Imidazo[1,2-a]pyridin-2-yl-derivate als schädlingsbekämpfungsmittel und deren zwischenprodukte |
| WO2017019828A1 (en) | 2015-07-30 | 2017-02-02 | Bristol-Myers Squibb Company | Aryl substituted bicyclic heteroaryl compounds |
| JP6903732B2 (ja) | 2016-07-14 | 2021-07-14 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | Ｐａｒ４阻害剤としての三環式ヘテロアリール置換のキノリンおよびアザキノリン化合物 |
| JP7058256B2 (ja) * | 2016-07-14 | 2022-04-21 | ブリストル－マイヤーズ スクイブ カンパニー | 二環式ヘテロアリール置換化合物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1473819A (en) * | 1976-01-28 | 1977-05-18 | Gallardo Antonio Sa | Derivatives of imidazo 1,2-a pyridine |
| ES8100015A1 (es) * | 1978-07-18 | 1980-04-01 | Hoechst Ag | Procedimiento para la preparacion de nuevos derivados de 2-(4-aminopiperidino)-3,4-dihidroquinoleina. |
| ES482439A0 (es) * | 1978-07-18 | 1980-04-01 | Hoechst Ag | Procedimiento para la preparacion de nuevos derivados de 1-(4-aminopiperidino)-3,4-dihidroisoquinoleina. |
| JPS5553284A (en) * | 1978-10-12 | 1980-04-18 | Yoshitomi Pharmaceut Ind Ltd | Pyridazinone derivative |
| GB2031404A (en) * | 1978-10-17 | 1980-04-23 | Yoshitomi Pharmaceutical | Pyridazinone compounds |
-
1981
- 1981-10-29 CA CA000389034A patent/CA1164459A/en not_active Expired
- 1981-11-10 PH PH26478A patent/PH17158A/en unknown
- 1981-11-10 PT PT73959A patent/PT73959B/pt not_active IP Right Cessation
- 1981-11-11 WO PCT/JP1981/000328 patent/WO1982001706A1/ja not_active Ceased
- 1981-11-11 MX MX819760U patent/MX6802E/es unknown
- 1981-11-11 KR KR1019810004359A patent/KR880001657B1/ko not_active Expired
- 1981-11-11 CH CH4324/82A patent/CH653684A5/fr not_active IP Right Cessation
- 1981-11-11 AU AU78085/81A patent/AU547586B2/en not_active Ceased
- 1981-11-11 ES ES507545A patent/ES507545A0/es active Granted
- 1981-11-11 EP EP81305344A patent/EP0052016B1/en not_active Expired
- 1981-11-11 AT AT0908381A patent/AT382376B/de not_active IP Right Cessation
- 1981-11-11 DE DE813152512T patent/DE3152512T1/de active Granted
- 1981-11-11 US US06/403,582 patent/US4414390A/en not_active Expired - Lifetime
- 1981-11-11 IT IT8149680A patent/IT8149680A0/it unknown
-
1982
- 1982-07-08 SE SE8204237A patent/SE440653B/sv not_active IP Right Cessation
- 1982-07-08 DK DK307482A patent/DK157193C/da not_active IP Right Cessation
- 1982-07-09 NO NO82822391A patent/NO157819C/no unknown
- 1982-07-11 SU SU823466402A patent/SU1215621A3/ru active
- 1982-07-12 FI FI822471A patent/FI71145C/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1982001706A1 (en) | 1982-05-27 |
| CH653684A5 (fr) | 1986-01-15 |
| DK157193C (da) | 1990-04-09 |
| ES8301967A1 (es) | 1983-02-01 |
| SE8204237L (sv) | 1982-07-08 |
| DE3152512C2 (no) | 1991-01-03 |
| SE8204237D0 (sv) | 1982-07-08 |
| AU7808581A (en) | 1982-06-07 |
| FI822471A0 (fi) | 1982-07-12 |
| FI822471L (fi) | 1982-07-12 |
| DK157193B (da) | 1989-11-20 |
| SU1215621A3 (ru) | 1986-02-28 |
| AT382376B (de) | 1987-02-25 |
| PT73959A (en) | 1981-12-01 |
| SE440653B (sv) | 1985-08-12 |
| ATA908381A (de) | 1986-07-15 |
| PT73959B (en) | 1983-04-18 |
| FI71145C (fi) | 1986-11-24 |
| IT8149680A0 (it) | 1981-11-11 |
| MX6802E (es) | 1986-07-29 |
| EP0052016B1 (en) | 1984-09-05 |
| EP0052016A1 (en) | 1982-05-19 |
| ES507545A0 (es) | 1983-02-01 |
| NO157819C (no) | 1988-05-25 |
| CA1164459A (en) | 1984-03-27 |
| US4414390A (en) | 1983-11-08 |
| KR830007644A (ko) | 1983-11-04 |
| DK307482A (da) | 1982-07-08 |
| AU547586B2 (en) | 1985-10-24 |
| PH17158A (en) | 1984-06-13 |
| FI71145B (fi) | 1986-08-14 |
| DE3152512T1 (de) | 1982-11-18 |
| NO157819B (no) | 1988-02-15 |
| KR880001657B1 (ko) | 1988-09-05 |
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