NO800931L - PROCEDURE FOR PREPARING MERCAPTO ACYLDIPEPTIDES - Google Patents

PROCEDURE FOR PREPARING MERCAPTO ACYLDIPEPTIDES

Info

Publication number: NO800931L
Authority: NO; Norway
Prior art keywords: acyldipeptides; procedure; preparing mercapto; mercapto; preparing
Prior art date: 1979-04-02

Application number

NO800931A

Other languages

Norwegian (no)

Other versions

NO150360B (en

NO150360C (en

Inventor

Miguel A Ondetti

Josip Pluscec

Original Assignee

Squibb & Sons Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-04-02

Filing date

1980-03-31

Publication date

1980-10-03

1980-03-31 Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc

1980-10-03 Publication of NO800931L publication Critical patent/NO800931L/en

1984-06-25 Publication of NO150360B publication Critical patent/NO150360B/en

1984-10-03 Publication of NO150360C publication Critical patent/NO150360C/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06052—Val-amino acid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Pharmacology & Pharmacy (AREA)
Cardiology (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Heart & Thoracic Surgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

NO800931A 1979-04-02 1980-03-31 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE BRAND CAPACYLDIPEPTIDES NO150360C (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US2570179A	1979-04-02	1979-04-02

Publications (3)

Publication Number	Publication Date
NO800931L true NO800931L (en)	1980-10-03
NO150360B NO150360B (en)	1984-06-25
NO150360C NO150360C (en)	1984-10-03

Family

ID=21827594

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO800931A NO150360C (en)	1979-04-02	1980-03-31	ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE BRAND CAPACYLDIPEPTIDES

Country Status (22)

Country	Link
JP (1)	JPS55133345A (en)
AT (1)	AT373577B (en)
AU (1)	AU537592B2 (en)
BE (1)	BE882601A (en)
CH (1)	CH645092A5 (en)
DE (1)	DE3012140A1 (en)
DK (1)	DK140480A (en)
ES (1)	ES8104200A1 (en)
FR (1)	FR2453135A1 (en)
GB (1)	GB2045771B (en)
GR (1)	GR67752B (en)
HU (1)	HU181087B (en)
IE (1)	IE49653B1 (en)
IT (1)	IT1147332B (en)
LU (1)	LU82316A1 (en)
NL (1)	NL8001675A (en)
NO (1)	NO150360C (en)
NZ (1)	NZ193142A (en)
PH (1)	PH22024A (en)
PT (1)	PT71044A (en)
SE (1)	SE8002512L (en)
ZA (1)	ZA801527B (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5692848A (en) *	1979-12-27	1981-07-27	Dainippon Pharmaceut Co Ltd	Preparation of 1- 3-lower alaknoylthio-2-methylpropanoyl prolylphenylalanine
JPS56139455A (en)	1980-04-02	1981-10-30	Santen Pharmaceut Co Ltd	Sulfur-containing acylaminoacid
US4336950A (en) *	1980-09-08	1982-06-29	John Zepkowski	Sled
US4462943A (en) *	1980-11-24	1984-07-31	E. R. Squibb & Sons, Inc.	Carboxyalkyl amino acid derivatives of various substituted prolines
JPS57142967A (en) *	1981-02-27	1982-09-03	Dainippon Pharmaceut Co Ltd	N-(acylthioalkanoyloxy)succinimide and its use
US4512979A (en) *	1981-03-23	1985-04-23	Merck & Co., Inc.	Dipeptides containing thialysine and related amino acids as antihypertensives
US4382081A (en) *	1981-06-12	1983-05-03	E. R. Squibb & Sons, Inc.	Inhibitors of mammalian collagenase
IT1195287B (en) *	1981-11-05	1988-10-12	Ausonia Farma Srl	THIAZOLIC DERIVATIVE, PROCEDURE FOR ITS PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS
US4434151A (en) *	1982-11-08	1984-02-28	Medi-Physics, Inc.	Bifunctional chelating agents
DE3243369A1 (en) *	1982-11-24	1984-05-24	Basf Ag, 6700 Ludwigshafen	BIS- (BENZOYLTHIO) CARBONIC ACIDS, THEIR PRODUCTION AND USE FOR THE PRODUCTION OF ACTIVE SUBSTANCES
US4642355A (en) *	1984-02-24	1987-02-10	Otsuka Pharmaceutical Factory, Inc.	Proline derivatives
US4560506A (en) *	1984-05-25	1985-12-24	E. R. Squibb & Sons, Inc.	Mercaptocycloalkylcarbonyl and mercaptoarylcarbonyl dipeptides
DE3432307A1 (en) *	1984-09-03	1986-04-10	Boehringer Ingelheim KG, 6507 Ingelheim	AMINO ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS
DE3436569A1 (en) *	1984-10-05	1986-04-10	Boehringer Ingelheim KG, 6507 Ingelheim	AMINO ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS
EP0245361A1 (en) *	1985-11-15	1987-11-19	The Upjohn Company	Novel renin inhibiting polypeptide analogs containing s-aryl-d- or l- or dl-cysteinyl, 3-(arylthio)lactic acid or 3-(arylthio)alkyl moieties
US4894437A (en) *	1985-11-15	1990-01-16	The Upjohn Company	Novel renin inhibiting polypeptide analogs containing S-aryl-D- or L- or DL-cysteinyl, 3-(arylthio)lactic acid or 3-(arylthio)alkyl moieties
JPH0662671B2 (en) *	1986-01-17	1994-08-17	株式会社大塚製薬工場	Proline derivative
DE69130605T2 (en) *	1991-02-27	1999-05-20	Lacer, S.A., Barcelona	Antihypertensive N- (alpha-substituted pyridyl) carbonyl dipeptides
FR2679564A1 (en) *	1991-07-23	1993-01-29	Inst Nat Sante Rech Med	NOVEL ACYLMERCAPTOALCANOLDIPEPTIDES, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM.
US5504080A (en) *	1992-10-28	1996-04-02	Bristol-Myers Squibb Co.	Benzo-fused lactams
GB9310075D0 (en) *	1993-05-17	1993-06-30	Fujisawa Pharmaceutical Co	New mercapto-amide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same
US7390789B2 (en) *	2005-09-13	2008-06-24	William H Simmons	Thio-containing inhibitors of aminopeptidase P, and compositions thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS559058A (en) *	1978-07-06	1980-01-22	Dainippon Pharmaceut Co Ltd	1-(3-mercapto-2-methylpropanoyl)prolyl amino acid derivative

1980
- 1980-03-12 AU AU56380/80A patent/AU537592B2/en not_active Ceased
- 1980-03-14 ZA ZA00801527A patent/ZA801527B/en unknown
- 1980-03-14 GB GB8008696A patent/GB2045771B/en not_active Expired
- 1980-03-17 NZ NZ193142A patent/NZ193142A/en unknown
- 1980-03-17 PH PH23775A patent/PH22024A/en unknown
- 1980-03-18 GR GR61475A patent/GR67752B/el unknown
- 1980-03-21 NL NL8001675A patent/NL8001675A/en not_active Application Discontinuation
- 1980-03-26 FR FR8006711A patent/FR2453135A1/en active Granted
- 1980-03-28 DE DE19803012140 patent/DE3012140A1/en not_active Withdrawn
- 1980-03-28 IE IE638/80A patent/IE49653B1/en not_active IP Right Cessation
- 1980-03-31 NO NO800931A patent/NO150360C/en unknown
- 1980-04-01 HU HU8080774A patent/HU181087B/en not_active IP Right Cessation
- 1980-04-01 ES ES490166A patent/ES8104200A1/en not_active Expired
- 1980-04-01 CH CH257180A patent/CH645092A5/en not_active IP Right Cessation
- 1980-04-01 LU LU82316A patent/LU82316A1/en unknown
- 1980-04-01 DK DK140480A patent/DK140480A/en not_active IP Right Cessation
- 1980-04-01 PT PT71044A patent/PT71044A/en not_active IP Right Cessation
- 1980-04-01 SE SE8002512A patent/SE8002512L/en not_active Application Discontinuation
- 1980-04-01 IT IT21110/80A patent/IT1147332B/en active
- 1980-04-02 AT AT0179480A patent/AT373577B/en not_active IP Right Cessation
- 1980-04-02 JP JP4402080A patent/JPS55133345A/en active Pending
- 1980-04-02 BE BE0/200091A patent/BE882601A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
FR2453135A1 (en)	1980-10-31
HU181087B (en)	1983-05-30
BE882601A (en)	1980-10-02
IE49653B1 (en)	1985-11-13
CH645092A5 (en)	1984-09-14
GB2045771B (en)	1983-01-26
AT373577B (en)	1984-02-10
IT8021110A0 (en)	1980-04-01
FR2453135B1 (en)	1983-06-17
PH22024A (en)	1988-05-13
IE800638L (en)	1980-10-02
AU5638080A (en)	1980-10-09
SE8002512L (en)	1980-10-03
ES490166A0 (en)	1981-04-01
ATA179480A (en)	1983-06-15
IT1147332B (en)	1986-11-19
DE3012140A1 (en)	1980-10-23
ZA801527B (en)	1981-03-25
JPS55133345A (en)	1980-10-17
PT71044A (en)	1980-05-01
GB2045771A (en)	1980-11-05
NO150360B (en)	1984-06-25
NL8001675A (en)	1980-10-06
DK140480A (en)	1980-10-03
LU82316A1 (en)	1980-12-16
NZ193142A (en)	1984-08-24
NO150360C (en)	1984-10-03
ES8104200A1 (en)	1981-04-01
GR67752B (en)	1981-09-18
AU537592B2 (en)	1984-07-05

Publication	Publication Date	Title
SE8100368L (en)	1981-01-22	PROCEDURE FOR PREPARING IMMUNOGAMMAGLOBULIN
ES490112A0 (en)	1981-01-16	PROCEDURE FOR PREPARING OXAZOLIDINATIONAS
FI803508L (en)	1981-05-13	PROCEDURE FOR IMMEDIATE IMMEDAZOLE-5-ACETIC SYREDER
SE7808485L (en)	1979-02-10	PROCEDURE FOR PREPARING OLIGOIMIDES
NO800931L (en)	1980-10-03	PROCEDURE FOR PREPARING MERCAPTO ACYLDIPEPTIDES
FI801541A7 (en)	1980-11-19	SAEKERHETSINDICATOR FOR LAST
RO76886A (en)	1982-02-01	PROCEDURE FOR PREPARING 9-IMINODIBENZOPIRANE
NO801796L (en)	1980-12-19	PROCEDURE FOR PREPARING 4-AROYLIMIDAZOLE-2-ONER
RO81115A (en)	1983-02-15	PROCEDURE FOR PREPARING D-6-N-PROPYLERGOLINE
NO800952L (en)	1980-10-06	PROCEDURE FOR MANUFACTURING ELECTRODEMASS
TR20825A (en)	1982-09-16	they FENILUER
SE7807240L (en)	1978-12-28	PROCEDURE FOR PREPARING PARA-BENZOCINONE
IT1143925B (en)	1986-10-29	PROCEDURE FOR PREPARING D-ALFAAM MINOACIDS
AR230624A1 (en)	1984-05-31	PROCEDURE FOR PREPARING OMEGA-CLAY (PROPIONIL OR BUTIRIL) -L-SUBSTITUTED PROLINS
ES496787A0 (en)	1981-11-01	PROCEDURE FOR PREPARING ANTI-ALLERGY-COS TRIACINIC COMPOUNDS
IT8048889A0 (en)	1980-06-05	PERFLUOROALKY COMPOUNDS AND PROCEDURE FOR PREPARING THEM
IT1122386B (en)	1986-04-23	PROCEDURE FOR PREPARING ISOPROPENYL-PHENOL
SE7904987L (en)	1980-09-30	HALLARE FOR VERMEROR
ES493569A0 (en)	1981-07-01	PROCEDURE FOR PREPARING ISOQUINOLINIC DERIVATIVES
NO800399L (en)	1980-08-18	PROCEDURE FOR PREPARING 7-ACYLINDOLIN-2-ONER
TR20812A (en)	1982-09-15	they FENILUER
ES489115A0 (en)	1981-11-01	PREPARATION PROCEDURE FOR PO-LIPHENOL GLYCYDIC POLYETERS
SE8003894L (en)	1980-11-26	PHOTOGLOR FOR SEGELBREDOR
NO791994L (en)	1979-12-18	PROCEDURE FOR PREPARING 2-ISOPROPYLAMINO-PYRIMIDINE
AT364444B (en)	1981-10-27	PROSTHESIS