NO312036B1 - Anvendelse av en polymer som et cellevekstsubstrat - Google Patents

Anvendelse av en polymer som et cellevekstsubstrat Download PDF

Info

Publication number: NO312036B1
Authority: NO; Norway
Prior art keywords: polymer; polymer according; tissue; implant; cells
Prior art date: 1995-04-04

Application number

NO19974583A

Other languages

English (en)

Norwegian (no)

Other versions

NO974583D0 (no

NO974583L (no

Inventor

Gordon Francis Meijs

Bronwyn Glenice Laycock

Madeleine Clare Griffiths

Edith Cheong

John Gerard Steele

Graham Johnson

Original Assignee

Commw Scient Ind Res Org

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-04-04

Filing date

1997-10-03

Publication date

2002-03-04

1995-04-04 Priority claimed from AUPN2160A external-priority patent/AUPN216095A0/en

1995-05-17 Priority claimed from AUPN3025A external-priority patent/AUPN302595A0/en

1997-10-03 Application filed by Commw Scient Ind Res Org filed Critical Commw Scient Ind Res Org

1997-10-03 Publication of NO974583D0 publication Critical patent/NO974583D0/no

1997-11-26 Publication of NO974583L publication Critical patent/NO974583L/no

2002-03-04 Publication of NO312036B1 publication Critical patent/NO312036B1/no

Links

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125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
XNGIFLGASWRNHJ-UHFFFAOYSA-L phthalate(2-) Chemical compound [O-]C(=O)C1=CC=CC=C1C([O-])=O XNGIFLGASWRNHJ-UHFFFAOYSA-L 0.000 description 1
239000002861 polymer material Substances 0.000 description 1
229920001296 polysiloxane Polymers 0.000 description 1
229920001343 polytetrafluoroethylene Polymers 0.000 description 1
239000004810 polytetrafluoroethylene Substances 0.000 description 1
230000002980 postoperative effect Effects 0.000 description 1
239000002243 precursor Substances 0.000 description 1
230000008569 process Effects 0.000 description 1
102000004196 processed proteins & peptides Human genes 0.000 description 1
108090000765 processed proteins & peptides Proteins 0.000 description 1
230000001737 promoting effect Effects 0.000 description 1
HJWLCRVIBGQPNF-UHFFFAOYSA-N prop-2-enylbenzene Chemical compound C=CCC1=CC=CC=C1 HJWLCRVIBGQPNF-UHFFFAOYSA-N 0.000 description 1
LYBIZMNPXTXVMV-UHFFFAOYSA-N propan-2-yl prop-2-enoate Chemical compound CC(C)OC(=O)C=C LYBIZMNPXTXVMV-UHFFFAOYSA-N 0.000 description 1
NHARPDSAXCBDDR-UHFFFAOYSA-N propyl 2-methylprop-2-enoate Chemical compound CCCOC(=O)C(C)=C NHARPDSAXCBDDR-UHFFFAOYSA-N 0.000 description 1
125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
PNXMTCDJUBJHQJ-UHFFFAOYSA-N propyl prop-2-enoate Chemical compound CCCOC(=O)C=C PNXMTCDJUBJHQJ-UHFFFAOYSA-N 0.000 description 1
125000001453 quaternary ammonium group Chemical group 0.000 description 1
239000011541 reaction mixture Substances 0.000 description 1
208000014733 refractive error Diseases 0.000 description 1
238000011160 research Methods 0.000 description 1
230000000241 respiratory effect Effects 0.000 description 1
230000004044 response Effects 0.000 description 1
230000003248 secreting effect Effects 0.000 description 1
239000004017 serum-free culture medium Substances 0.000 description 1
229910052708 sodium Inorganic materials 0.000 description 1
239000011734 sodium Substances 0.000 description 1
MNCGMVDMOKPCSQ-UHFFFAOYSA-M sodium;2-phenylethenesulfonate Chemical compound [Na+].[O-]S(=O)(=O)C=CC1=CC=CC=C1 MNCGMVDMOKPCSQ-UHFFFAOYSA-M 0.000 description 1
HPALAKNZSZLMCH-UHFFFAOYSA-M sodium;chloride;hydrate Chemical compound O.[Na+].[Cl-] HPALAKNZSZLMCH-UHFFFAOYSA-M 0.000 description 1
BWYYYTVSBPRQCN-UHFFFAOYSA-M sodium;ethenesulfonate Chemical compound [Na+].[O-]S(=O)(=O)C=C BWYYYTVSBPRQCN-UHFFFAOYSA-M 0.000 description 1
239000011877 solvent mixture Substances 0.000 description 1
241000894007 species Species 0.000 description 1
230000007480 spreading Effects 0.000 description 1
238000003892 spreading Methods 0.000 description 1
238000010186 staining Methods 0.000 description 1
238000010561 standard procedure Methods 0.000 description 1
150000003431 steroids Chemical class 0.000 description 1
238000013517 stratification Methods 0.000 description 1
210000002536 stromal cell Anatomy 0.000 description 1
150000003440 styrenes Chemical class 0.000 description 1
125000001424 substituent group Chemical group 0.000 description 1
230000008093 supporting effect Effects 0.000 description 1
230000003319 supportive effect Effects 0.000 description 1
239000004094 surface-active agent Substances 0.000 description 1
230000002459 sustained effect Effects 0.000 description 1
230000009885 systemic effect Effects 0.000 description 1
WMOVHXAZOJBABW-UHFFFAOYSA-N tert-butyl acetate Chemical compound CC(=O)OC(C)(C)C WMOVHXAZOJBABW-UHFFFAOYSA-N 0.000 description 1
125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
DVKJHBMWWAPEIU-UHFFFAOYSA-N toluene 2,4-diisocyanate Chemical compound CC1=CC=C(N=C=O)C=C1N=C=O DVKJHBMWWAPEIU-UHFFFAOYSA-N 0.000 description 1
RUELTTOHQODFPA-UHFFFAOYSA-N toluene 2,6-diisocyanate Chemical compound CC1=C(N=C=O)C=CC=C1N=C=O RUELTTOHQODFPA-UHFFFAOYSA-N 0.000 description 1
125000003944 tolyl group Chemical group 0.000 description 1
238000011200 topical administration Methods 0.000 description 1
238000012876 topography Methods 0.000 description 1
239000012780 transparent material Substances 0.000 description 1
ILWRPSCZWQJDMK-UHFFFAOYSA-N triethylazanium;chloride Chemical compound Cl.CCN(CC)CC ILWRPSCZWQJDMK-UHFFFAOYSA-N 0.000 description 1
GETQZCLCWQTVFV-UHFFFAOYSA-N trimethylamine Chemical compound CN(C)C GETQZCLCWQTVFV-UHFFFAOYSA-N 0.000 description 1
238000009281 ultraviolet germicidal irradiation Methods 0.000 description 1
125000005065 undecenyl group Chemical class C(=CCCCCCCCCC)* 0.000 description 1
230000002792 vascular Effects 0.000 description 1
230000035899 viability Effects 0.000 description 1
229920001567 vinyl ester resin Polymers 0.000 description 1
229960000834 vinyl ether Drugs 0.000 description 1
230000004304 visual acuity Effects 0.000 description 1
BPICBUSOMSTKRF-UHFFFAOYSA-N xylazine Chemical compound CC1=CC=CC(C)=C1NC1=NCCCS1 BPICBUSOMSTKRF-UHFFFAOYSA-N 0.000 description 1
229960001600 xylazine Drugs 0.000 description 1
125000005023 xylyl group Chemical group 0.000 description 1

Classifications

- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C7/00—Optical parts
- G02C7/02—Lenses; Lens systems ; Methods of designing lenses
- G02C7/04—Contact lenses for the eyes
- G02C7/049—Contact lenses having special fitting or structural features achieved by special materials or material structures
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
- A61F2/142—Cornea, e.g. artificial corneae, keratoprostheses or corneal implants for repair of defective corneal tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/26—Mixtures of macromolecular compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D1/00—Processes for applying liquids or other fluent materials
- B05D1/62—Plasma-deposition of organic layers
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C39/00—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
- B29C39/22—Component parts, details or accessories; Auxiliary operations
- B29C39/42—Casting under special conditions, e.g. vacuum
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
- B29D11/00—Producing optical elements, e.g. lenses or prisms
- B29D11/00009—Production of simple or compound lenses
- B29D11/00038—Production of contact lenses
- B29D11/00076—Production of contact lenses enabling passage of fluids, e.g. oxygen, tears, between the area under the lens and the lens exterior
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
- C08F290/02—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
- C08F290/06—Polymers provided for in subclass C08G
- C08F290/062—Polyethers
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/08—Processes
- C08G18/10—Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/40—High-molecular-weight compounds
- C08G18/48—Polyethers
- C08G18/4833—Polyethers containing oxyethylene units
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/40—High-molecular-weight compounds
- C08G18/48—Polyethers
- C08G18/50—Polyethers having heteroatoms other than oxygen
- C08G18/5003—Polyethers having heteroatoms other than oxygen having halogens
- C08G18/5015—Polyethers having heteroatoms other than oxygen having halogens having fluorine atoms
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/40—High-molecular-weight compounds
- C08G18/61—Polysiloxanes
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
- C08G18/81—Unsaturated isocyanates or isothiocyanates
- C08G18/8108—Unsaturated isocyanates or isothiocyanates having only one isocyanate or isothiocyanate group
- C08G18/8116—Unsaturated isocyanates or isothiocyanates having only one isocyanate or isothiocyanate group esters of acrylic or alkylacrylic acid having only one isocyanate or isothiocyanate group
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Biomedical Technology (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Biotechnology (AREA)
Polymers & Plastics (AREA)
Microbiology (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
Ophthalmology & Optometry (AREA)
Transplantation (AREA)
Cell Biology (AREA)
Oral & Maxillofacial Surgery (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Dermatology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Physics & Mathematics (AREA)
Mechanical Engineering (AREA)
Vascular Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Optics & Photonics (AREA)
General Physics & Mathematics (AREA)
Cardiology (AREA)
Manufacturing & Machinery (AREA)
Plasma & Fusion (AREA)
Materials For Medical Uses (AREA)
Apparatus Associated With Microorganisms And Enzymes (AREA)

NO19974583A 1995-04-04 1997-10-03 Anvendelse av en polymer som et cellevekstsubstrat NO312036B1 (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
AUPN2160A AUPN216095A0 (en)	1995-04-04	1995-04-04	Novel materials
AUPN3025A AUPN302595A0 (en)	1995-05-17	1995-05-17	Novel materials
PCT/EP1996/001340 WO1996031548A1 (fr)	1995-04-04	1996-03-27	Polymeres pour substrats de culture de cellules

Publications (3)

Publication Number	Publication Date
NO974583D0 NO974583D0 (no)	1997-10-03
NO974583L NO974583L (no)	1997-11-26
NO312036B1 true NO312036B1 (no)	2002-03-04

Family

ID=25644894

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19974583A NO312036B1 (no)	1995-04-04	1997-10-03	Anvendelse av en polymer som et cellevekstsubstrat

Country Status (19)

Country	Link
US (1)	US5994133A (fr)
EP (1)	EP0819141B1 (fr)
JP (1)	JP3805790B2 (fr)
KR (1)	KR19980703533A (fr)
CN (1)	CN1121430C (fr)
AT (1)	ATE187971T1 (fr)
AU (1)	AU707836B2 (fr)
CA (1)	CA2215138C (fr)
DE (1)	DE69605778T2 (fr)
DK (1)	DK0819141T3 (fr)
ES (1)	ES2141485T3 (fr)
GR (1)	GR3032585T3 (fr)
IL (1)	IL117750A0 (fr)
MX (1)	MX9707594A (fr)
NO (1)	NO312036B1 (fr)
NZ (1)	NZ304330A (fr)
PT (1)	PT819141E (fr)
TW (1)	TW340127B (fr)
WO (1)	WO1996031548A1 (fr)

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TWI230712B (en)	1998-09-15	2005-04-11	Novartis Ag	Polymers
US6245106B1 (en) *	1998-10-29	2001-06-12	Allergan Sales, Inc.	Intraocular lenses made from polymeric compositions and monomers useful in said compositions
USRE38935E1 (en)	1998-10-29	2006-01-10	Advanced Medical Optics, Inc.	Intraocular lenses made from polymeric compositions and monomers useful in said compositions
AR021240A1 (es) *	1998-11-13	2002-07-03	Commw Scient Ind Res Org	Peptidos acoplados
WO2000049058A1 (fr) *	1999-02-18	2000-08-24	Novartis Ag	Nouveaux biomateriaux
WO2000078830A1 (fr) *	1999-06-22	2000-12-28	Novartis Ag	Procede pour produire des objets moules
US6255360B1 (en) *	2000-05-15	2001-07-03	Novartis Ag	Process for the manufacture of moldings
US6544286B1 (en) *	2000-07-18	2003-04-08	Tissue Engineering Refraction, Inc.	Pre-fabricated corneal tissue lens method of corneal overlay to correct vision
US6534307B1 (en) *	2001-02-08	2003-03-18	Clinomics Biosciences, Inc.	Frozen tissue microarrayer
US7026484B2 (en) *	2001-02-23	2006-04-11	Ligand Pharmaceuticals Incorporated	Tricyclic androgen receptor modulator compounds and methods
MXPA04006954A (es)	2002-01-17	2005-03-23	Perez Edward	Metodos para producir colgajos epiteliales sobre la cornea y para la colocacion de dispositivos oculares y lentes debajo de un colgajo o membrana epitelial, dispositivo de deslaminacion epitelial, y estructuras de epitelio y dispositivos y lentes ocu
EP1364663A1 (fr) *	2002-05-21	2003-11-26	Commonwealth Scientific And Industrial Research Organisation	Dispositifs oculaires avec surface fonctionalisée conférant des propriétés adhésives
US7476398B1 (en)	2002-06-28	2009-01-13	Universite Laval	Corneal implant and uses thereof
AU2003270593A1 (en) *	2002-09-13	2004-04-30	Ocular Sciences, Inc.	Devices and methods for improving vision
WO2007074449A2 (fr) *	2005-12-28	2007-07-05	Seng Enterprises Ltd.	Structure tridimensionnelle sensiblement invisible pour l'étude de cellules
US9200245B2 (en)	2003-06-26	2015-12-01	Seng Enterprises Ltd.	Multiwell plate
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US9040090B2 (en)	2003-12-19	2015-05-26	The University Of North Carolina At Chapel Hill	Isolated and fixed micro and nano structures and methods thereof
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US20050273146A1 (en) *	2003-12-24	2005-12-08	Synecor, Llc	Liquid perfluoropolymers and medical applications incorporating same
US20050142315A1 (en) *	2003-12-24	2005-06-30	Desimone Joseph M.	Liquid perfluoropolymers and medical applications incorporating same
US20050271794A1 (en) *	2003-12-24	2005-12-08	Synecor, Llc	Liquid perfluoropolymers and medical and cosmetic applications incorporating same
KR20070055422A (ko) *	2004-05-20	2007-05-30	쿠퍼비젼,인코포레이티드	시력 향상을 위한 각막 온레이 및 파면 수차 보정
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1996
- 1996-03-27 KR KR1019970706937A patent/KR19980703533A/ko not_active Ceased
- 1996-03-27 PT PT96908142T patent/PT819141E/pt unknown
- 1996-03-27 AU AU51490/96A patent/AU707836B2/en not_active Ceased
- 1996-03-27 DE DE69605778T patent/DE69605778T2/de not_active Expired - Lifetime
- 1996-03-27 EP EP96908142A patent/EP0819141B1/fr not_active Expired - Lifetime
- 1996-03-27 CN CN96192999A patent/CN1121430C/zh not_active Expired - Fee Related
- 1996-03-27 NZ NZ304330A patent/NZ304330A/xx not_active IP Right Cessation
- 1996-03-27 AT AT96908142T patent/ATE187971T1/de not_active IP Right Cessation
- 1996-03-27 US US08/793,204 patent/US5994133A/en not_active Expired - Lifetime
- 1996-03-27 ES ES96908142T patent/ES2141485T3/es not_active Expired - Lifetime
- 1996-03-27 CA CA002215138A patent/CA2215138C/fr not_active Expired - Fee Related
- 1996-03-27 DK DK96908142T patent/DK0819141T3/da active
- 1996-03-27 JP JP52994896A patent/JP3805790B2/ja not_active Expired - Fee Related
- 1996-03-27 MX MX9707594A patent/MX9707594A/es not_active IP Right Cessation
- 1996-03-27 WO PCT/EP1996/001340 patent/WO1996031548A1/fr not_active Ceased
- 1996-04-01 IL IL11775096A patent/IL117750A0/xx unknown
1997
- 1997-03-19 TW TW086103440A patent/TW340127B/zh active
- 1997-10-03 NO NO19974583A patent/NO312036B1/no not_active IP Right Cessation
2000
- 2000-02-04 GR GR20000400280T patent/GR3032585T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
TW340127B (en)	1998-09-11
AU707836B2 (en)	1999-07-22
EP0819141B1 (fr)	1999-12-22
CN1121430C (zh)	2003-09-17
KR19980703533A (ko)	1998-11-05
JPH11503473A (ja)	1999-03-26
NO974583D0 (no)	1997-10-03
CN1180361A (zh)	1998-04-29
WO1996031548A1 (fr)	1996-10-10
GR3032585T3 (en)	2000-05-31
CA2215138C (fr)	2007-04-24
ES2141485T3 (es)	2000-03-16
ATE187971T1 (de)	2000-01-15
NZ304330A (en)	1999-05-28
PT819141E (pt)	2000-05-31
CA2215138A1 (fr)	1996-10-10
DE69605778D1 (de)	2000-01-27
JP3805790B2 (ja)	2006-08-09
EP0819141A1 (fr)	1998-01-21
DK0819141T3 (da)	2000-05-29
MX9707594A (es)	1997-12-31
AU5149096A (en)	1996-10-23
IL117750A0 (en)	1996-08-04
DE69605778T2 (de)	2000-07-20
NO974583L (no)	1997-11-26
US5994133A (en)	1999-11-30

Publication	Publication Date	Title
NO312036B1 (no)	2002-03-04	Anvendelse av en polymer som et cellevekstsubstrat
US6255360B1 (en)	2001-07-03	Process for the manufacture of moldings
JP4344013B2 (ja)	2009-10-14	重合性ペルフルオロアルキルエーテルマクロマー
US6503958B2 (en)	2003-01-07	Biomaterials
US5981615A (en)	1999-11-09	Polymerizable siloxane macromonomers
US6225367B1 (en)	2001-05-01	Polymers
NO324788B1 (no)	2007-12-10	Perfluoralkyletere inneholdende polysiloksaner, fremstilling derav og deres anvendelse, polymer omfattende polymerisasjonsproduktet av minst en av nevnte forbindelser samt formlegeme, biomedisinsk artikkel, kornealt implantat og cellevekstsubstrat omfattende denne.
CZ427098A3 (cs)	1999-03-17	Amfifilní segmentový kopolymer s regulovanou morfologií a oční prostředky zahrnující kontaktní čočky zhotovené z tohoto kopolymeru
JP3967378B2 (ja)	2007-08-29	重合性ペルフルオロアルキルエーテルシロキサンマクロマー
Borrelli et al.	2023	Keratin films for ocular surface reconstruction: Wound healing in an in-vivo model
JP2003502493A (ja)	2003-01-21	成形物の製造方法
CN1187827A (zh)	1998-07-15	可聚合的硅氧烷大单体
MXPA97010041A (en)	1998-10-15	Macromonomeros de siloxano polimerizab

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