NO3034079T3 - - Google Patents
Info
- Publication number
- NO3034079T3 NO3034079T3 NO15187794A NO15187794A NO3034079T3 NO 3034079 T3 NO3034079 T3 NO 3034079T3 NO 15187794 A NO15187794 A NO 15187794A NO 15187794 A NO15187794 A NO 15187794A NO 3034079 T3 NO3034079 T3 NO 3034079T3
- Authority
- NO
- Norway
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41397110P | 2010-11-15 | 2010-11-15 | |
| EP11841746.8A EP2640391B1 (fr) | 2010-11-15 | 2011-11-15 | Dérivés de pyridazine, compositions et méthodes de traitement d'une déficience cognitive |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO3034079T3 true NO3034079T3 (fr) | 2018-06-09 |
Family
ID=46084380
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO15187794A NO3034079T3 (fr) | 2010-11-15 | 2011-11-15 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9145372B2 (fr) |
| EP (2) | EP2640391B1 (fr) |
| JP (1) | JP5916746B2 (fr) |
| CN (1) | CN103313712B (fr) |
| AU (1) | AU2011328993B2 (fr) |
| BR (1) | BR112013012062B1 (fr) |
| CA (1) | CA2818025A1 (fr) |
| DK (2) | DK3034079T3 (fr) |
| EA (1) | EA027840B1 (fr) |
| MX (2) | MX383953B (fr) |
| NO (1) | NO3034079T3 (fr) |
| WO (1) | WO2012068161A1 (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012068161A1 (fr) | 2010-11-15 | 2012-05-24 | Agenebio, Inc. | Dérivés de pyridazine, compositions et méthodes de traitement d'une déficience cognitive |
| EP2642919A4 (fr) * | 2010-11-26 | 2014-10-08 | Brigham & Womens Hospital | Procédé d'évaluation de lésions traumatiques de la tête répétitives à l'aide de spectroscopie de résonance magnétique bidimensionnelle |
| JP2015529254A (ja) | 2012-09-21 | 2015-10-05 | ユーダブリューエム・リサーチ・ファウンデーション，インコーポレーテッド | 喘息における気道の過敏症及び炎症を制御するための新規なｇａｂａａアゴニスト及び使用方法 |
| WO2014078377A1 (fr) * | 2012-11-14 | 2014-05-22 | Agenebio, Inc. | Méthodes et compositions pour le traitement de la schizophrénie |
| CA3123897C (fr) | 2013-12-20 | 2024-02-06 | Agenebio, Inc. | Derives de benzodiazepine, compositions et procedes de traitement de la deficience cognitive |
| MA42624A (fr) | 2015-06-19 | 2021-04-28 | Agenebio Inc | Dérivés de benzodiazépine, compositions et méthodes de traitement de la déficience cognitive |
| TWI697485B (zh) * | 2015-07-21 | 2020-07-01 | 日商捷恩智股份有限公司 | 含唑啉環的化合物、含有其的電子輸送/注入層用材料、使用其的有機電致發光元件、顯示裝置及照明裝置 |
| US11505555B2 (en) | 2016-12-19 | 2022-11-22 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| EA202190076A1 (ru) | 2018-06-19 | 2021-09-22 | Эйджинбайо, Инк. | Производные бензодиазепина, композиции и способы лечения когнитивных нарушений |
| US11862337B2 (en) | 2019-03-19 | 2024-01-02 | Cambridge Cognition Limited | Method and uses of diagnosing and recommending treatment for a psychotic disorder |
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| ES413944A1 (es) | 1972-04-20 | 1976-06-01 | Merz & Co | Procedimiento para la preparacion de compuestos de adamen- tano trisustituidos en las posiciones 1,3,5. |
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| DE2856393C2 (de) | 1978-12-27 | 1983-04-28 | Merz + Co GmbH & Co, 6000 Frankfurt | Arzneimittel zur Behandlung von Morbus Parkinson |
| US4804663A (en) | 1985-03-27 | 1989-02-14 | Janssen Pharmaceutica N.V. | 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles |
| IE58370B1 (en) | 1985-04-10 | 1993-09-08 | Lundbeck & Co As H | Indole derivatives |
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| ATE94384T1 (de) | 1989-04-14 | 1993-10-15 | Merz & Co Gmbh & Co | Verwendung von adamantan-derivaten zur praevention und behandlung der cerebralen ischaemie. |
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| KR20030076717A (ko) | 2001-03-01 | 2003-09-26 | 화이자 프로덕츠 인크. | 인지 장애의 치료를 위한 니코틴 수용체 부분 아고니스트,에스트로겐, 선택적 에스트로겐 조정자 또는 비타민 ｅ와함께, ｇａｂａａ 역아고니스트의 용도 |
| AU2002313737A1 (en) | 2001-08-13 | 2003-04-01 | University Of Kentucky Research Foundation | Gene expression profile biomarkers and therapeutic targets for brain aging and age-related cognitive impairment |
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| US7635709B2 (en) | 2002-09-26 | 2009-12-22 | The United States Of America As Represented By The Department Of Veterans Affairs | Compositions and methods for bowel care in individuals with chronic intestinal pseudo-obstruction |
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| KR20050083971A (ko) | 2002-11-22 | 2005-08-26 | 더 존스 홉킨스 유니버시티 | 인지능 손상의 치료를 위한 표적 |
| EP1682109B1 (fr) | 2003-10-22 | 2008-10-15 | Merz Pharma GmbH & Co. KGaA | Utilisation de derives de 1-aminocyclohexane pour modifier le depot de peptides a_g(b) fibrillogenes dans des amyloidopathies |
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| US8510055B2 (en) | 2005-08-03 | 2013-08-13 | The Johns Hopkins University | Methods for characterizing and treating cognitive impairment in aging and disease |
| EP1924712B1 (fr) | 2005-08-03 | 2018-10-03 | The Johns Hopkins University | Méthodes permettant de caractériser et de traiter un trouble cognitif dû au vieillissement ou à une maladie |
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| EP2318005B1 (fr) | 2008-08-01 | 2017-11-01 | Lixte Biotechnology, Inc. | Agents neuroprotecteurs pour la prévention et le traitement de maladies neurodégénératives |
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| JP2013516497A (ja) | 2010-01-11 | 2013-05-13 | ミスリィディオン，インク． | 認知増強のための化合物と組成物、製造方法、および治療方法 |
| JP2013542266A (ja) | 2010-11-15 | 2013-11-21 | エージンバイオ， インコーポレイテッド | 認知障害を処置するためのベンゾジアゼピン誘導体、組成物、および方法 |
| WO2012068161A1 (fr) | 2010-11-15 | 2012-05-24 | Agenebio, Inc. | Dérivés de pyridazine, compositions et méthodes de traitement d'une déficience cognitive |
| JPWO2012161133A1 (ja) * | 2011-05-20 | 2014-07-31 | 日産化学工業株式会社 | 置換ピリダジン化合物及び農園芸用殺菌剤 |
| EP2892521A4 (fr) | 2012-09-10 | 2016-06-29 | Ophirex Inc | Administration d'inhibiteurs d'acétylcholinestérase pour atténuer une paralysie induite par une neurotoxique et un blocage neuromusculaire résiduel |
| CA3123897C (fr) | 2013-12-20 | 2024-02-06 | Agenebio, Inc. | Derives de benzodiazepine, compositions et procedes de traitement de la deficience cognitive |
-
2011
- 2011-11-15 WO PCT/US2011/060854 patent/WO2012068161A1/fr not_active Ceased
- 2011-11-15 US US13/885,569 patent/US9145372B2/en not_active Expired - Fee Related
- 2011-11-15 CN CN201180063261.2A patent/CN103313712B/zh not_active Expired - Fee Related
- 2011-11-15 JP JP2013539003A patent/JP5916746B2/ja active Active
- 2011-11-15 NO NO15187794A patent/NO3034079T3/no unknown
- 2011-11-15 EP EP11841746.8A patent/EP2640391B1/fr active Active
- 2011-11-15 MX MX2017003111A patent/MX383953B/es unknown
- 2011-11-15 AU AU2011328993A patent/AU2011328993B2/en not_active Ceased
- 2011-11-15 MX MX2013005442A patent/MX346185B/es active IP Right Grant
- 2011-11-15 CA CA2818025A patent/CA2818025A1/fr not_active Abandoned
- 2011-11-15 BR BR112013012062-2A patent/BR112013012062B1/pt not_active IP Right Cessation
- 2011-11-15 DK DK15187794.1T patent/DK3034079T3/en active
- 2011-11-15 EP EP15187794.1A patent/EP3034079B1/fr active Active
- 2011-11-15 DK DK11841746.8T patent/DK2640391T3/da active
- 2011-11-15 EA EA201390712A patent/EA027840B1/ru not_active IP Right Cessation
-
2015
- 2015-09-18 US US14/858,959 patent/US9801879B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3034079A1 (fr) | 2016-06-22 |
| US20160008357A1 (en) | 2016-01-14 |
| DK2640391T3 (da) | 2016-02-15 |
| JP2013542267A (ja) | 2013-11-21 |
| EP2640391B1 (fr) | 2015-11-11 |
| EP2640391A4 (fr) | 2014-05-07 |
| AU2011328993A1 (en) | 2013-06-06 |
| AU2011328993B2 (en) | 2017-03-02 |
| CA2818025A1 (fr) | 2012-05-24 |
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| EA027840B1 (ru) | 2017-09-29 |
| BR112013012062A2 (pt) | 2016-08-16 |
| WO2012068161A1 (fr) | 2012-05-24 |
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| BR112013012062B1 (pt) | 2020-06-02 |