NO2501822T3 - - Google Patents
Info
- Publication number
- NO2501822T3 NO2501822T3 NO10782133A NO10782133A NO2501822T3 NO 2501822 T3 NO2501822 T3 NO 2501822T3 NO 10782133 A NO10782133 A NO 10782133A NO 10782133 A NO10782133 A NO 10782133A NO 2501822 T3 NO2501822 T3 NO 2501822T3
- Authority
- NO
- Norway
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/30—Extraction; Separation; Purification by precipitation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/02—Separating microorganisms from their culture media
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26188609P | 2009-11-17 | 2009-11-17 | |
| PCT/US2010/056924 WO2011062926A2 (fr) | 2009-11-17 | 2010-11-17 | Procédés pour une production améliorée de protéine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO2501822T3 true NO2501822T3 (fr) | 2018-01-13 |
Family
ID=43480207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO10782133A NO2501822T3 (fr) | 2009-11-17 | 2010-11-17 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US8765415B2 (fr) |
| EP (3) | EP3255153A1 (fr) |
| CY (1) | CY1119923T1 (fr) |
| DK (1) | DK2501822T3 (fr) |
| ES (1) | ES2642629T3 (fr) |
| HR (1) | HRP20171701T8 (fr) |
| HU (1) | HUE035508T2 (fr) |
| LT (1) | LT2501822T (fr) |
| NO (1) | NO2501822T3 (fr) |
| PL (1) | PL2501822T3 (fr) |
| PT (1) | PT2501822T (fr) |
| RS (1) | RS56484B1 (fr) |
| SI (1) | SI2501822T1 (fr) |
| SM (1) | SMT201700529T1 (fr) |
| WO (1) | WO2011062926A2 (fr) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2188371B1 (fr) * | 2007-08-09 | 2017-12-20 | Wyeth LLC | Utilisation de la perfusion pour améliorer la production d'une culture cellulaire en mode semi-continu dans des bioréacteurs |
| US8691145B2 (en) | 2009-11-16 | 2014-04-08 | Flodesign Sonics, Inc. | Ultrasound and acoustophoresis for water purification |
| HUE035508T2 (en) * | 2009-11-17 | 2018-05-02 | Squibb & Sons Llc | Methods for enhanced protein production |
| US8506797B2 (en) * | 2011-04-10 | 2013-08-13 | Therapeutic Proteins International, LLC | Downstream bioprocessing device |
| JP5897708B2 (ja) | 2011-07-01 | 2016-03-30 | アムジエン・インコーポレーテツド | 哺乳類細胞培養物 |
| US8852435B2 (en) * | 2011-11-29 | 2014-10-07 | Therapeutics Proteins International, LLC | Purification and separation treatment assembly (PASTA) for biological products |
| US9272234B2 (en) | 2012-03-15 | 2016-03-01 | Flodesign Sonics, Inc. | Separation of multi-component fluid through ultrasonic acoustophoresis |
| US10689609B2 (en) | 2012-03-15 | 2020-06-23 | Flodesign Sonics, Inc. | Acoustic bioreactor processes |
| US9950282B2 (en) | 2012-03-15 | 2018-04-24 | Flodesign Sonics, Inc. | Electronic configuration and control for acoustic standing wave generation |
| US10967298B2 (en) | 2012-03-15 | 2021-04-06 | Flodesign Sonics, Inc. | Driver and control for variable impedence load |
| US9752114B2 (en) | 2012-03-15 | 2017-09-05 | Flodesign Sonics, Inc | Bioreactor using acoustic standing waves |
| US9796956B2 (en) | 2013-11-06 | 2017-10-24 | Flodesign Sonics, Inc. | Multi-stage acoustophoresis device |
| US9752113B2 (en) | 2012-03-15 | 2017-09-05 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| US10953436B2 (en) | 2012-03-15 | 2021-03-23 | Flodesign Sonics, Inc. | Acoustophoretic device with piezoelectric transducer array |
| US9458450B2 (en) | 2012-03-15 | 2016-10-04 | Flodesign Sonics, Inc. | Acoustophoretic separation technology using multi-dimensional standing waves |
| US9783775B2 (en) | 2012-03-15 | 2017-10-10 | Flodesign Sonics, Inc. | Bioreactor using acoustic standing waves |
| US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| US10322949B2 (en) | 2012-03-15 | 2019-06-18 | Flodesign Sonics, Inc. | Transducer and reflector configurations for an acoustophoretic device |
| US9745548B2 (en) | 2012-03-15 | 2017-08-29 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| US10370635B2 (en) | 2012-03-15 | 2019-08-06 | Flodesign Sonics, Inc. | Acoustic separation of T cells |
| US9567559B2 (en) | 2012-03-15 | 2017-02-14 | Flodesign Sonics, Inc. | Bioreactor using acoustic standing waves |
| US10737953B2 (en) | 2012-04-20 | 2020-08-11 | Flodesign Sonics, Inc. | Acoustophoretic method for use in bioreactors |
| TWI637057B (zh) * | 2012-11-09 | 2018-10-01 | 拜爾沙納有限公司 | 具交替生物反應器用途之不連續進料批次製程 |
| US9745569B2 (en) | 2013-09-13 | 2017-08-29 | Flodesign Sonics, Inc. | System for generating high concentration factors for low cell density suspensions |
| KR102245547B1 (ko) * | 2013-09-30 | 2021-04-28 | 얀센 백신스 앤드 프리벤션 비.브이. | 고밀도의 미정제 세포 배양 수거물의 정화를 위한 방법 |
| US9725710B2 (en) | 2014-01-08 | 2017-08-08 | Flodesign Sonics, Inc. | Acoustophoresis device with dual acoustophoretic chamber |
| BR112016018797A8 (pt) * | 2014-02-17 | 2020-06-23 | Advantech Bioscience Farm Ltda | aperfeiçoamento de expressão de proteína recombinante com o uso de um sistema de retenção de célula baseado em membrana |
| EP3119871A4 (fr) * | 2014-03-17 | 2018-01-03 | Regeneron Pharmaceuticals, Inc. | Clarification de culture cellulaire de mammifère |
| KR20160138477A (ko) * | 2014-03-23 | 2016-12-05 | 어드밴텍 바이오사이언스 파마큐티카 엘티디에이 | 구리를 이용한 재조합 단백질의 발현 증가 방법 |
| AU2015240353A1 (en) | 2014-04-01 | 2016-11-17 | Advantech Bioscience Farmaceutica Ltda. | Stable Factor VIII formulations with low sugar-glycine |
| AU2015240354A1 (en) | 2014-04-01 | 2016-11-17 | Advantech Bioscience Farmaceutica Ltda. | Stabilization of Factor VIII without calcium as an excipient |
| US9744483B2 (en) | 2014-07-02 | 2017-08-29 | Flodesign Sonics, Inc. | Large scale acoustic separation device |
| CN105296433B (zh) | 2014-08-01 | 2018-02-09 | 中山康方生物医药有限公司 | 一种ctla4抗体、其药物组合物及其用途 |
| IL253071B2 (en) * | 2014-12-22 | 2024-04-01 | Genzyme Corp | Methods for growing mammalian cells |
| US10106770B2 (en) | 2015-03-24 | 2018-10-23 | Flodesign Sonics, Inc. | Methods and apparatus for particle aggregation using acoustic standing waves |
| US10640760B2 (en) | 2016-05-03 | 2020-05-05 | Flodesign Sonics, Inc. | Therapeutic cell washing, concentration, and separation utilizing acoustophoresis |
| US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
| US11377651B2 (en) | 2016-10-19 | 2022-07-05 | Flodesign Sonics, Inc. | Cell therapy processes utilizing acoustophoresis |
| US11021699B2 (en) | 2015-04-29 | 2021-06-01 | FioDesign Sonics, Inc. | Separation using angled acoustic waves |
| JP6737813B2 (ja) * | 2015-05-29 | 2020-08-12 | グリコトープ ゲーエムベーハー | 懸濁細胞の小スケール培養 |
| US11459540B2 (en) | 2015-07-28 | 2022-10-04 | Flodesign Sonics, Inc. | Expanded bed affinity selection |
| US11474085B2 (en) | 2015-07-28 | 2022-10-18 | Flodesign Sonics, Inc. | Expanded bed affinity selection |
| US10710006B2 (en) | 2016-04-25 | 2020-07-14 | Flodesign Sonics, Inc. | Piezoelectric transducer for generation of an acoustic standing wave |
| US11214789B2 (en) | 2016-05-03 | 2022-01-04 | Flodesign Sonics, Inc. | Concentration and washing of particles with acoustics |
| US11085035B2 (en) | 2016-05-03 | 2021-08-10 | Flodesign Sonics, Inc. | Therapeutic cell washing, concentration, and separation utilizing acoustophoresis |
| WO2018035710A1 (fr) | 2016-08-23 | 2018-03-01 | Akeso Biopharma, Inc. | Anticorps anti-ctla4 |
| JP2020513248A (ja) | 2016-10-19 | 2020-05-14 | フロデザイン ソニックス, インク.Flodesign Sonics, Inc. | 音響による親和性細胞抽出 |
| IL273549B2 (en) | 2017-10-06 | 2023-10-01 | Lonza Ag | Automated control of cell culture using Raman spectroscopy |
| ES2919850T3 (es) | 2017-10-16 | 2022-07-28 | Regeneron Pharma | Procedimientos de perfusión |
| US10785574B2 (en) | 2017-12-14 | 2020-09-22 | Flodesign Sonics, Inc. | Acoustic transducer driver and controller |
| NZ777640A (en) * | 2019-02-15 | 2025-11-28 | Merck Sharp & Dohme | Automated biomanufacturing systems, facilities, and processes |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US5476996A (en) | 1988-06-14 | 1995-12-19 | Lidak Pharmaceuticals | Human immune system in non-human animal |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| ATE139258T1 (de) | 1990-01-12 | 1996-06-15 | Cell Genesys Inc | Erzeugung xenogener antikörper |
| US6075181A (en) | 1990-01-12 | 2000-06-13 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
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| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
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| US5770429A (en) | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
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| US5877397A (en) | 1990-08-29 | 1999-03-02 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5814318A (en) | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US6300129B1 (en) | 1990-08-29 | 2001-10-09 | Genpharm International | Transgenic non-human animals for producing heterologous antibodies |
| EP0667901B2 (fr) | 1991-10-25 | 2008-10-15 | Immunex Corporation | Nouvelle cytokine |
| ES2341666T3 (es) | 1991-12-02 | 2010-06-24 | Medimmune Limited | Produccion de autoanticuerpos de repertorios de segmentos de anticue rpos expresados en la superficie de fagos. |
| EP0746609A4 (fr) | 1991-12-17 | 1997-12-17 | Genpharm Int | Animaux transgeniques non humains capables de produire des anticorps heterologues |
| JPH08509612A (ja) | 1993-04-26 | 1996-10-15 | ジェンファーム インターナショナル インコーポレイテッド | 異種抗体を産生することができるトランスジェニック非ヒト動物 |
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| IL122174A (en) | 1995-06-07 | 2004-07-25 | Immunex Corp | Dna encoding a cd40l mutein and a cd40l polypeptide encoded by said dna |
| CN1371416B (zh) | 1999-08-24 | 2012-10-10 | 梅达里克斯公司 | 人ctla-4抗体及其应用 |
| ES2405944T3 (es) | 2000-11-30 | 2013-06-04 | Medarex, Inc. | Ácidos nucleicos que codifican las secuencias de inmunoglobulina humana reorganizadas a partir de ratones transcromoscómicos transgénicos zadas |
| AU2002316230A1 (en) | 2001-06-13 | 2002-12-23 | Genentech, Inc. | Methods of culturing animal cells and polypeptide production in animal cells |
| EP1720972B1 (fr) | 2004-03-05 | 2014-01-08 | DSM IP Assets B.V. | Culture de cellules en perfusion continue et flux alternatif tangentiel |
| FR2884255B1 (fr) | 2005-04-11 | 2010-11-05 | Vivalis | Utilisation de lignees de cellules souches aviaires ebx pour la production de vaccin contre la grippe |
| WO2008024769A2 (fr) | 2006-08-21 | 2008-02-28 | Raven Biotechnologies, Inc. | Procédé de production de perfusion intensifiée |
| JP5732196B2 (ja) * | 2006-11-01 | 2015-06-10 | バイオジェン アイデック エムエー インコーポレイティドBiogen Idec Inc. | 低pHおよび二価カチオンを用いる生物高分子を単離する方法 |
| US9012180B2 (en) * | 2007-03-02 | 2015-04-21 | Wyeth Llc | Use of copper and glutamate in cell culture for production of polypeptides |
| EP2188371B1 (fr) * | 2007-08-09 | 2017-12-20 | Wyeth LLC | Utilisation de la perfusion pour améliorer la production d'une culture cellulaire en mode semi-continu dans des bioréacteurs |
| CN102056936A (zh) * | 2008-06-09 | 2011-05-11 | 丹尼斯科美国公司 | 从发酵液中回收不溶解酶和不溶解酶的制剂 |
| JP5746025B2 (ja) * | 2008-07-16 | 2015-07-08 | ケーセップ・システムズ,リミテッド・ライアビリティ・カンパニー | 流動床を使用して粒子を操作するための方法及びシステム |
| US20110184154A1 (en) * | 2008-10-17 | 2011-07-28 | Percivia Llc | Cell broth clarification and host cell protein removal |
| EP2419436A1 (fr) * | 2009-04-13 | 2012-02-22 | Bristol-Myers Squibb Company | Purification de protéines par précipitation par un citrate |
| HUE035508T2 (en) * | 2009-11-17 | 2018-05-02 | Squibb & Sons Llc | Methods for enhanced protein production |
| ES2869232T3 (es) * | 2013-02-26 | 2021-10-25 | Emd Millipore Corp | Eliminación selectiva de una proteína de una mezcla de proteínas mediante el uso de carbón activado mediante el ajuste de las condiciones de la solución |
-
2010
- 2010-11-17 HU HUE10782133A patent/HUE035508T2/en unknown
- 2010-11-17 SI SI201031532T patent/SI2501822T1/sl unknown
- 2010-11-17 PL PL10782133T patent/PL2501822T3/pl unknown
- 2010-11-17 RS RS20171124A patent/RS56484B1/sr unknown
- 2010-11-17 DK DK10782133.2T patent/DK2501822T3/da active
- 2010-11-17 US US13/510,372 patent/US8765415B2/en active Active
- 2010-11-17 PT PT107821332T patent/PT2501822T/pt unknown
- 2010-11-17 LT LTEP10782133.2T patent/LT2501822T/lt unknown
- 2010-11-17 HR HRP20171701TT patent/HRP20171701T8/hr unknown
- 2010-11-17 EP EP17183182.9A patent/EP3255153A1/fr not_active Withdrawn
- 2010-11-17 EP EP18177245.0A patent/EP3431608A3/fr active Pending
- 2010-11-17 ES ES10782133.2T patent/ES2642629T3/es active Active
- 2010-11-17 WO PCT/US2010/056924 patent/WO2011062926A2/fr not_active Ceased
- 2010-11-17 NO NO10782133A patent/NO2501822T3/no unknown
- 2010-11-17 EP EP10782133.2A patent/EP2501822B1/fr not_active Revoked
- 2010-11-17 SM SM20170529T patent/SMT201700529T1/it unknown
-
2014
- 2014-06-19 US US14/309,308 patent/US20140302581A1/en not_active Abandoned
-
2017
- 2017-10-30 CY CY20171101129T patent/CY1119923T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3431608A3 (fr) | 2019-02-20 |
| HUE035508T2 (en) | 2018-05-02 |
| SMT201700529T1 (it) | 2018-01-11 |
| RS56484B1 (sr) | 2018-01-31 |
| WO2011062926A2 (fr) | 2011-05-26 |
| PL2501822T3 (pl) | 2017-12-29 |
| ES2642629T3 (es) | 2017-11-17 |
| US20140302581A1 (en) | 2014-10-09 |
| WO2011062926A3 (fr) | 2011-07-21 |
| HRP20171701T1 (hr) | 2017-12-15 |
| US8765415B2 (en) | 2014-07-01 |
| US20130017577A1 (en) | 2013-01-17 |
| SI2501822T1 (sl) | 2017-10-30 |
| EP2501822A2 (fr) | 2012-09-26 |
| HRP20171701T8 (hr) | 2018-02-23 |
| EP3255153A1 (fr) | 2017-12-13 |
| DK2501822T3 (da) | 2017-11-27 |
| PT2501822T (pt) | 2017-10-18 |
| CY1119923T1 (el) | 2018-12-12 |
| EP2501822B1 (fr) | 2017-08-16 |
| LT2501822T (lt) | 2017-10-25 |
| EP3431608A2 (fr) | 2019-01-23 |