NO2015005I2 - Flutemetamol (18F) - Google Patents

Flutemetamol (18F)

Info

Publication number: NO2015005I2
Authority: NO; Norway
Prior art keywords: fluoromethamol
Prior art date: 2003-03-14

Application number

NO2015005C

Other languages

English (en)

Other versions

NO2015005I1 (no

Original Assignee

Univ Pittsburgh Commonwealth Sys Higher Education

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-03-14

Filing date

2015-02-18

Publication date

2015-02-18

2003-03-14 Priority claimed from US10/388,173 external-priority patent/US7270800B2/en

2003-08-22 Priority claimed from US10/645,847 external-priority patent/US20050043523A1/en

2004-03-15 Priority claimed from PCT/US2004/007797 external-priority patent/WO2004083195A1/en

2015-02-18 Application filed by Univ Pittsburgh Commonwealth Sys Higher Education filed Critical Univ Pittsburgh Commonwealth Sys Higher Education

2015-02-18 Publication of NO2015005I2 publication Critical patent/NO2015005I2/no

2015-03-02 Publication of NO2015005I1 publication Critical patent/NO2015005I1/no

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
- C07D277/66—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
General Physics & Mathematics (AREA)
Cell Biology (AREA)
Food Science & Technology (AREA)
Biotechnology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Pathology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Magnetic Resonance Imaging Apparatus (AREA)
Thiazole And Isothizaole Compounds (AREA)

NO2015005C 2003-03-14 2015-02-18 Flutemetamol (18F) NO2015005I1 (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US10/388,173 US7270800B2 (en)	2000-08-24	2003-03-14	Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition
US10/645,847 US20050043523A1 (en)	2003-08-22	2003-08-22	Benzothiazole derivative compounds, compositions and uses
PCT/US2004/007797 WO2004083195A1 (en)	2003-03-14	2004-03-15	Benzothiazole derivative compounds, compositions and uses

Publications (2)

Publication Number	Publication Date
NO2015005I2 true NO2015005I2 (no)	2015-02-18
NO2015005I1 NO2015005I1 (no)	2015-03-02

Family

ID=35057877

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
NO20054674A NO330861B1 (no)	2003-03-14	2005-10-11	Benzotiazolavledede forbindelser, preparater og anvendelser
NO20110980A NO20110980L (no)	2003-03-14	2011-07-06	Benzotiazolavledede forbindelser, preparater og anvendelser
NO2015005C NO2015005I1 (no)	2003-03-14	2015-02-18	Flutemetamol (18F)

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
NO20054674A NO330861B1 (no)	2003-03-14	2005-10-11	Benzotiazolavledede forbindelser, preparater og anvendelser
NO20110980A NO20110980L (no)	2003-03-14	2011-07-06	Benzotiazolavledede forbindelser, preparater og anvendelser

Country Status (16)

Country	Link
EP (1)	EP1611115B1 (no)
JP (1)	JP4875487B2 (no)
CN (2)	CN102532055B (no)
AU (2)	AU2004221897B2 (no)
BE (1)	BE2015C005I2 (no)
BR (1)	BRPI0408274B8 (no)
CY (2)	CY1113334T1 (no)
DK (1)	DK1611115T3 (no)
ES (1)	ES2393921T3 (no)
FR (1)	FR15C0005I2 (no)
HU (1)	HUS1500006I1 (no)
NO (3)	NO330861B1 (no)
PL (1)	PL1611115T3 (no)
PT (1)	PT1611115E (no)
RU (1)	RU2440995C2 (no)
SI (1)	SI1611115T1 (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7270800B2 (en)	2000-08-24	2007-09-18	University Of Pittsburgh	Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition
RU2324686C2 (ru)	2000-08-24	2008-05-20	Юнивесити Оф Питсбэг	ПРОИЗВОДНЫЕ ТИОФЛАВИНА, СВЯЗЫВАЮЩИЕ АМИЛОИД, СПОСОБ ОБНАРУЖЕНИЯ in vivo ОТЛОЖЕНИЙ АМИЛОИДА И СПОСОБ РАСПОЗНАВАНИЯ БОЛЕЗНИ АЛЬЦГЕЙМЕРА
CN101198598A (zh) *	2004-05-20	2008-06-11	弗尔德里克斯制药股份有限公司	2-((杂)芳基)-苯并噁唑化合物及其衍生物、组合物以及用于稳定和抑制甲状腺素转运蛋白错重叠的方法
GB0516564D0 (en) *	2005-08-12	2005-09-21	Ge Healthcare Ltd	Fluorination process
KR101503940B1 (ko) *	2007-01-30	2015-03-18	지이 헬쓰케어 리미티드	신경퇴행성 질환의 진단을 돕는 수단
CN101293878B (zh) *	2007-04-25	2010-12-15	中国科学院上海应用物理研究所	苯并噻唑苯胺类化合物及其制备方法和应用
CA2731738A1 (en) *	2008-07-24	2010-01-28	Siemens Medical Solutions Usa, Inc.	Imaging agents useful for identifying ad pathology
JP5667058B2 (ja) *	2008-09-23	2015-02-12	ウィスタラボラトリーズリミテッド	凝集したタウ分子に対するリガンド
JP6182668B2 (ja) *	2013-09-26	2017-08-16	エフ．ホフマン−ラロシュアーゲーＦ．Ｈｏｆｆｍａｎｎ−ＬａＲｏｃｈｅＡｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ	画像化ツールとしてのイミダゾ［１，２−ａ］ピリジン−７−アミン
JP6260967B2 (ja) *	2013-11-06	2018-01-17	国立大学法人京都大学	放射性ヨウ素標識化合物、及び、これを含む放射性医薬
CN103613589B (zh) *	2013-11-29	2016-03-30	江苏华益科技有限公司	一种用于神经退行性疾病领域的新型pet显像剂前体及标准品的合成方法
US10907197B2 (en) *	2014-08-29	2021-02-02	Chdi Foundation, Inc.	Probes for imaging huntingtin protein
CN109400615B (zh) *	2017-08-18	2021-07-16	上海交通大学医学院附属新华医院	一种靶向β-淀粉样蛋白的香豆素类化合物及其制备与应用
GR1009516B (el) *	2018-03-22	2019-05-02	Εκεφε Δημοκριτος	Τρικαρβονυλο-συμπλοκα μεταλλων μεταπτωσεως με βενζο-ετεροκυκλικο παραγωγο του κυκλοπενταδιενυλικου ανιοντος με υψηλη διαπερατοτητα του αιματοεγκεφαλικου φραγμου για εφαρμογες στη διαγνωση και θεραπεια νοσων του κνς
CN119462558B (zh) *	2024-10-18	2025-09-19	河南中医药大学	一种布美他尼衍生物及其制备方法和用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2001519769A (ja) *	1996-11-22	2001-10-23	エラン・ファーマシューティカルズ・インコーポレイテッド	Ｎ―（アリール／ヘテロアリール）アミノ酸誘導体、その医薬組成物および該化合物を用いたβ―アミロイドペプチドの放出および／またはその合成を阻害する方法
GB9919673D0 (en) *	1999-08-20	1999-10-20	Cancer Res Campaign Tech	2-Arlybenzazole compounds
RU2324686C2 (ru) *	2000-08-24	2008-05-20	Юнивесити Оф Питсбэг	ПРОИЗВОДНЫЕ ТИОФЛАВИНА, СВЯЗЫВАЮЩИЕ АМИЛОИД, СПОСОБ ОБНАРУЖЕНИЯ in vivo ОТЛОЖЕНИЙ АМИЛОИДА И СПОСОБ РАСПОЗНАВАНИЯ БОЛЕЗНИ АЛЬЦГЕЙМЕРА
EP1345914A1 (en) *	2000-12-22	2003-09-24	AstraZeneca AB	Therapeutic compounds
JP4317955B2 (ja) *	2001-04-23	2009-08-19	ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア	アミロイド斑凝集阻害剤および診断用造影剤
GB0229686D0 (en) *	2002-12-20	2003-01-29	Amersham Plc	Solid-phase fluorination of benzothiazoles

2004
- 2004-03-15 DK DK04720788.1T patent/DK1611115T3/da active
- 2004-03-15 JP JP2006507179A patent/JP4875487B2/ja not_active Expired - Lifetime
- 2004-03-15 SI SI200431952T patent/SI1611115T1/sl unknown
- 2004-03-15 CN CN201110437182.5A patent/CN102532055B/zh not_active Expired - Lifetime
- 2004-03-15 RU RU2005131872/04A patent/RU2440995C2/ru not_active Application Discontinuation
- 2004-03-15 CN CNA2004800125035A patent/CN1784392A/zh active Pending
- 2004-03-15 PT PT47207881T patent/PT1611115E/pt unknown
- 2004-03-15 EP EP04720788A patent/EP1611115B1/en not_active Expired - Lifetime
- 2004-03-15 BR BRPI0408274A patent/BRPI0408274B8/pt active IP Right Grant
- 2004-03-15 AU AU2004221897A patent/AU2004221897B2/en not_active Expired
- 2004-03-15 ES ES04720788T patent/ES2393921T3/es not_active Expired - Lifetime
- 2004-03-15 PL PL04720788T patent/PL1611115T3/pl unknown
2005
- 2005-10-11 NO NO20054674A patent/NO330861B1/no active Protection Beyond IP Right Term
2011
- 2011-02-16 AU AU2011200667A patent/AU2011200667B2/en not_active Expired
- 2011-07-06 NO NO20110980A patent/NO20110980L/no not_active Application Discontinuation
2012
- 2012-11-16 CY CY20121101106T patent/CY1113334T1/el unknown
2015
- 2015-01-21 FR FR15C0005C patent/FR15C0005I2/fr active Active
- 2015-01-27 BE BE2015C005C patent/BE2015C005I2/fr unknown
- 2015-02-18 NO NO2015005C patent/NO2015005I1/no not_active IP Right Cessation
- 2015-02-18 HU HUS1500006C patent/HUS1500006I1/hu unknown
- 2015-03-04 CY CY2015007C patent/CY2015007I1/el unknown

Also Published As

Publication number	Publication date
SI1611115T1 (sl)	2012-12-31
EP1611115A1 (en)	2006-01-04
PT1611115E (pt)	2012-12-07
CY2015007I1 (el)	2015-12-09
AU2011200667A1 (en)	2011-03-10
JP4875487B2 (ja)	2012-02-15
JP2006522104A (ja)	2006-09-28
NO20054674D0 (no)	2005-10-11
PL1611115T3 (pl)	2013-01-31
BRPI0408274B8 (pt)	2021-05-25
AU2004221897A9 (en)	2009-08-20
BE2015C005I2 (no)	2023-03-07
NO20110980L (no)	2005-12-13
BRPI0408274B1 (pt)	2019-02-26
HUS1500006I1 (hu)	2015-02-18
AU2011200667B2 (en)	2011-12-22
NO2015005I1 (no)	2015-03-02
ES2393921T3 (es)	2013-01-02
FR15C0005I2 (fr)	2015-07-24
NO330861B1 (no)	2011-08-01
EP1611115B1 (en)	2012-08-22
CN102532055B (zh)	2016-05-11
AU2004221897B2 (en)	2010-11-18
DK1611115T3 (da)	2012-11-26
CY1113334T1 (el)	2015-12-09
CN1784392A (zh)	2006-06-07
RU2005131872A (ru)	2006-02-27
AU2004221897A1 (en)	2004-09-30
BRPI0408274A (pt)	2006-03-21
NO20054674L (no)	2005-12-13
RU2440995C2 (ru)	2012-01-27
HK1086270A1 (en)	2006-09-15
AU2004221897A2 (en)	2004-09-30
CN102532055A (zh)	2012-07-04

Publication	Publication Date	Title
LU92647I2 (fr)	2015-11-03	Florbetaben (18f)
NO2015005I1 (no)	2015-03-02	Flutemetamol (18F)
DE602004018654D1 (de)	2009-02-05	Se
ATE363383T1 (de)	2007-06-15	Schlingenware
AT502792A5 (de)	2007-05-15	Düsenanpressvorrichtung
DE502004009566D1 (de)	2009-07-16	Raftfahrzeug
DE502004007911D1 (de)	2008-10-02	Wischblatt
DE112004000620D2 (de)	2005-12-22	Struktoguss
DE502004008321D1 (de)	2008-12-04	Bandaufwickelverfahren
DE502004000672D1 (de)	2006-07-20	Pigmentpreparationen
DE502004001524D1 (de)	2006-11-02	Hydrolager
ATA662003A (de)	2005-11-15	Trink-mundstück
ATE446959T1 (de)	2009-11-15	Chromenonindole
DE502004002978D1 (de)	2007-04-05	N-biarylamide
DE502004001629D1 (de)	2006-11-16	Bremsenprüfstand
DE502004003122D1 (de)	2007-04-19	Hydrolager
DE502004006563D1 (de)	2008-04-30	Brieftaubenkonstatiersystem
DE112004002227D2 (de)	2006-07-27	Nietverarbeitungsgerät
DE502004005162D1 (de)	2007-11-15	Leistungsregelvorricthung
DE502004008889D1 (de)	2009-03-05	Schaltgabel
DE502004000518D1 (de)	2006-06-14	Mitgängergabelhubwagen
DE10394329D2 (de)	2006-10-05	Mäanderstent
DE10329218B4 (de)	2007-05-16	Hotflue
DE502004007959D1 (de)	2008-10-09	Prolinylarylacetamide
DE502004007251D1 (de)	2008-07-03	En 2-arylpropenalen

Legal Events

Date	Code	Title	Description
2016-01-18	MK1K	Patent expired