NO20091022L - Vaksine omfattende en olje i vann emulsjons-adjuvant - Google Patents
Vaksine omfattende en olje i vann emulsjons-adjuvantInfo
- Publication number
- NO20091022L NO20091022L NO20091022A NO20091022A NO20091022L NO 20091022 L NO20091022 L NO 20091022L NO 20091022 A NO20091022 A NO 20091022A NO 20091022 A NO20091022 A NO 20091022A NO 20091022 L NO20091022 L NO 20091022L
- Authority
- NO
- Norway
- Prior art keywords
- oil
- water emulsion
- vaccine
- emulsion adjuvant
- composition
- Prior art date
Links
- 239000007764 o/w emulsion Substances 0.000 title abstract 3
- 239000002671 adjuvant Substances 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- DFUSDJMZWQVQSF-XLGIIRLISA-N (2r)-2-methyl-2-[(4r,8r)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-ol Chemical compound OC1=CC=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1 DFUSDJMZWQVQSF-XLGIIRLISA-N 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 239000003995 emulsifying agent Substances 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/295—Polyvalent viral antigens; Mixtures of viral and bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Abstract
Foreliggende oppfinnelse tilveiebringer en immunogen sammensetning omfattende et antigen eller antigen sammensetning og en adjuvans sammensetning omfattende en olje-i-vann emulsjon, hvor nevnte olje-i-vann emulsjon omfatter 0,5-10 mg metaboliserbar olje, 0,5-11 mg tocol og 0,1-4 mg emulgeringsmiddel, pr. human dose.
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0620336.8A GB0620336D0 (en) | 2006-10-12 | 2006-10-12 | Vaccine |
| GB0620337A GB0620337D0 (en) | 2006-10-12 | 2006-10-12 | Vaccine |
| GB0620816A GB0620816D0 (en) | 2006-10-19 | 2006-10-19 | vaccine |
| GB0620815A GB0620815D0 (en) | 2006-10-19 | 2006-10-19 | Vaccine |
| PCT/EP2006/069979 WO2007071711A2 (en) | 2005-12-22 | 2006-12-20 | Vaccine |
| PCT/EP2006/069977 WO2007071710A2 (en) | 2005-12-22 | 2006-12-20 | Vaccine comprising streptococcus pneumoniae capsular polysaccharide conjugates |
| GB0707697A GB0707697D0 (en) | 2007-04-20 | 2007-04-20 | Vaccine |
| GB0711357A GB0711357D0 (en) | 2007-06-12 | 2007-06-12 | Vaccine |
| GB0712062A GB0712062D0 (en) | 2007-06-21 | 2007-06-21 | Vaccine |
| PCT/EP2007/060743 WO2008043774A1 (en) | 2006-10-12 | 2007-10-10 | Vaccine comprising an oil in water emulsion adjuvant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20091022L true NO20091022L (no) | 2009-04-27 |
Family
ID=40551582
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20091022A NO20091022L (no) | 2006-10-12 | 2009-03-10 | Vaksine omfattende en olje i vann emulsjons-adjuvant |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US20100183667A1 (no) |
| JP (2) | JP5230632B2 (no) |
| KR (1) | KR101151202B1 (no) |
| CN (1) | CN101522218B (no) |
| AU (1) | AU2007306381B2 (no) |
| BR (1) | BRPI0717219B8 (no) |
| CA (1) | CA2664619C (no) |
| CR (1) | CR10726A (no) |
| DK (1) | DK2086582T3 (no) |
| EA (1) | EA015817B1 (no) |
| ES (1) | ES2397714T3 (no) |
| HR (1) | HRP20130023T1 (no) |
| IL (1) | IL197512A (no) |
| MA (1) | MA30866B1 (no) |
| MX (1) | MX2009003325A (no) |
| NO (1) | NO20091022L (no) |
| PT (1) | PT2086582E (no) |
| WO (1) | WO2008043774A1 (no) |
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| JP4812942B2 (ja) * | 1999-02-26 | 2011-11-09 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | CGモチーフを含むオリゴヌクレオチドを用いるNeisseria抗原殺菌活性の増強 |
| DE10144906B4 (de) | 2001-09-12 | 2013-11-28 | Novartis Vaccines And Diagnostics Gmbh | Verfahren zur großtechnischen Herstellung von Impfstoffen |
| DK1861120T3 (en) * | 2005-03-23 | 2016-07-25 | Glaxosmithkline Biologicals Sa | Use of an influenza virus and an oil-in-water emulsion adjuvant to induce CD 4 T cell and / or enhanced B memory cell response |
| PL2043682T3 (pl) | 2006-07-17 | 2014-09-30 | Glaxosmithkline Biologicals Sa | Szczepionka przeciw grypie |
| CN101522218B (zh) * | 2006-10-12 | 2012-09-26 | 葛兰素史密丝克莱恩生物有限公司 | 包含水包油乳液佐剂的疫苗 |
| CA2668405C (en) | 2006-11-03 | 2015-05-05 | Schering-Plough Ltd. | Canine lyme disease vaccine |
| AR066405A1 (es) | 2007-04-20 | 2009-08-19 | Glaxosmithkline Biolog Sa | Vacuna |
| GB0714963D0 (en) | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
| EP2268309B1 (en) | 2008-03-18 | 2015-01-21 | Novartis AG | Improvements in preparation of influenza virus vaccine antigens |
| ES2553113T3 (es) * | 2008-04-16 | 2015-12-04 | Glaxosmithkline Biologicals S.A. | Vacuna |
| KR20110009158A (ko) * | 2008-04-16 | 2011-01-27 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 백신 |
| ES2366941T3 (es) | 2008-08-28 | 2011-10-26 | Novartis Ag | Producción de escualeno a partir de levaduras hiperproductoras. |
| EP2331127A2 (en) | 2008-09-18 | 2011-06-15 | Novartis AG | Vaccine adjuvant combinations |
| EA201500910A1 (ru) * | 2009-02-10 | 2016-04-29 | Новартис Аг | Вакцины против гриппа со сниженным количеством сквалена |
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| US20120093859A1 (en) | 2009-02-10 | 2012-04-19 | Novartis Ag | Influenza vaccine regimens for pandemic-associated strains |
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| NZ595291A (en) | 2009-03-24 | 2013-08-30 | Novartis Ag | Combinations of meningococcal factor h binding protein and pneumococcal saccharide conjugates |
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| SI2401384T1 (sl) | 2009-05-21 | 2013-01-31 | Novartis Ag | Reverzna genetika z uporabo neendogenih pol i promotorjev |
| JP2013500712A (ja) | 2009-07-31 | 2013-01-10 | ノバルティス アーゲー | 逆遺伝学系 |
| GB0918392D0 (en) | 2009-10-20 | 2009-12-02 | Novartis Ag | Diagnostic and therapeutic methods |
| EP2491117B2 (en) | 2009-10-20 | 2017-06-28 | Novartis AG | Improved reverse genetics methods for virus rescue |
| GB0919117D0 (en) | 2009-10-30 | 2009-12-16 | Glaxosmithkline Biolog Sa | Process |
| GB0919690D0 (en) | 2009-11-10 | 2009-12-23 | Guy S And St Thomas S Nhs Foun | compositions for immunising against staphylococcus aureus |
| CN102869372B (zh) | 2010-01-27 | 2016-01-20 | 葛兰素史密丝克莱恩生物有限公司 | 经修饰的结核抗原 |
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| EA027142B1 (ru) | 2010-05-12 | 2017-06-30 | Новартис Аг | Улучшенные способы получения сквалена |
| CN103025350A (zh) | 2010-05-21 | 2013-04-03 | 诺华有限公司 | 流感病毒的重配方法 |
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| ES2564138T3 (es) | 2011-12-12 | 2016-03-18 | Novartis Ag | Ensayo para Hemaglutinina del virus de la influenza |
| EP2793939A1 (en) | 2011-12-23 | 2014-10-29 | Novartis AG | Stable compositions for immunising against staphylococcus aureus |
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| AU2013229432A1 (en) | 2012-03-08 | 2014-10-16 | Novartis Ag | Adjuvanted formulations of booster vaccines |
| CN104582723A (zh) | 2012-08-31 | 2015-04-29 | 诺华股份有限公司 | 用于针对金黄色葡萄球菌的免疫的稳定化的蛋白质 |
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| AU2014264501A1 (en) | 2013-05-10 | 2015-12-10 | Novartis Ag | Avoiding narcolepsy risk in influenza vaccines |
| PT3542819T (pt) * | 2013-05-14 | 2021-10-14 | Zoetis Services Llc | Composições de vacina inovadoras que compreendem oligonucleótidos imunoestimulantes |
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| KR102576962B1 (ko) | 2015-07-07 | 2023-09-11 | 세퀴러스 유케이 리미티드 | 인플루엔자 효능 검정 |
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- 2007-10-10 KR KR1020097009716A patent/KR101151202B1/ko active Active
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- 2007-10-10 HR HRP20130023TT patent/HRP20130023T1/hr unknown
- 2007-10-10 BR BRPI0717219A patent/BRPI0717219B8/pt not_active IP Right Cessation
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Also Published As
| Publication number | Publication date |
|---|---|
| US20150359863A1 (en) | 2015-12-17 |
| CN101522218B (zh) | 2012-09-26 |
| DK2086582T3 (da) | 2013-02-04 |
| CN101522218A (zh) | 2009-09-02 |
| MA30866B1 (fr) | 2009-11-02 |
| BRPI0717219B1 (pt) | 2021-01-19 |
| CA2664619A1 (en) | 2008-04-17 |
| JP2010505907A (ja) | 2010-02-25 |
| ES2397714T3 (es) | 2013-03-08 |
| US20100183667A1 (en) | 2010-07-22 |
| WO2008043774A1 (en) | 2008-04-17 |
| EA015817B1 (ru) | 2011-12-30 |
| CR10726A (es) | 2009-05-25 |
| AU2007306381B2 (en) | 2011-12-08 |
| BRPI0717219B8 (pt) | 2021-05-25 |
| JP2013067646A (ja) | 2013-04-18 |
| EA200900350A1 (ru) | 2009-10-30 |
| JP5230632B2 (ja) | 2013-07-10 |
| BRPI0717219A2 (pt) | 2015-05-26 |
| HRP20130023T1 (hr) | 2013-02-28 |
| JP5767201B2 (ja) | 2015-08-19 |
| IL197512A (en) | 2013-10-31 |
| PT2086582E (pt) | 2013-01-25 |
| IL197512A0 (en) | 2011-08-01 |
| US9700605B2 (en) | 2017-07-11 |
| KR101151202B1 (ko) | 2012-06-11 |
| AU2007306381A1 (en) | 2008-04-17 |
| CA2664619C (en) | 2012-12-11 |
| KR20090066323A (ko) | 2009-06-23 |
| MX2009003325A (es) | 2009-04-09 |
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