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NO20090201L - Nye heteroarylsubstituerte benzoksazoler - Google Patents

Nye heteroarylsubstituerte benzoksazoler

Info

Publication number
NO20090201L
NO20090201L NO20090201A NO20090201A NO20090201L NO 20090201 L NO20090201 L NO 20090201L NO 20090201 A NO20090201 A NO 20090201A NO 20090201 A NO20090201 A NO 20090201A NO 20090201 L NO20090201 L NO 20090201L
Authority
NO
Norway
Prior art keywords
methods
relates
alzheimer
compositions
compounds
Prior art date
Application number
NO20090201A
Other languages
English (en)
Inventor
Daniel Sohn
Jonas Malmstrom
David Pyring
Can Slivo
Britt-Marie Swahn
David Wensbo
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38833677&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20090201(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20090201L publication Critical patent/NO20090201L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Foreliggende oppfinnelse omhandler nye heteroarylsubstituerte benzoksazolderivater og terapeutiske anvendelser for slike forbindelser, som har den strukturelle formel (Ia) under:. [Kjemisk formel skal settes inn her. Se papirkopi] og deres farmasøytisk akseptable salt, sammensetninger og fremgangsmåter for anvendelse. Dessuten omhandler oppfinnelsen nye heteroarylsubstituerte benzoksazolderivater som er egnet for avbildning av amyloide avsetninger i levende pasienter, deres sammensetninger, fremgangsmåter for anvendelse og fremgangsmåter for fremstilling av slike forbindelser. Mer spesifikt omhandler foreliggende oppfinnelse en fremgangsmåte for avbildning av amyloide avsetninger i hjerne in vivo for å tillate antemortem diagnose av Alzheimers sykdom så vel som måling av klinisk virksomhet av Alzheimers sykdom terapeutiske midler.
NO20090201A 2006-06-19 2009-01-13 Nye heteroarylsubstituerte benzoksazoler NO20090201L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81493606P 2006-06-19 2006-06-19
PCT/SE2007/000591 WO2007149030A1 (en) 2006-06-19 2007-06-18 Novel heteroaryl substituted benzoxazoles

Publications (1)

Publication Number Publication Date
NO20090201L true NO20090201L (no) 2009-01-13

Family

ID=38833677

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20090201A NO20090201L (no) 2006-06-19 2009-01-13 Nye heteroarylsubstituerte benzoksazoler

Country Status (16)

Country Link
US (1) US7670591B2 (no)
EP (1) EP2035418A1 (no)
JP (1) JP5548842B2 (no)
KR (1) KR20090021224A (no)
CN (1) CN101506201B (no)
AR (1) AR061515A1 (no)
AU (1) AU2007261786A1 (no)
CA (1) CA2655084A1 (no)
CL (1) CL2007001784A1 (no)
IL (1) IL195669A0 (no)
MX (1) MX2008015718A (no)
NO (1) NO20090201L (no)
TW (1) TW200813035A (no)
UY (1) UY30419A1 (no)
WO (1) WO2007149030A1 (no)
ZA (1) ZA200810163B (no)

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US8779149B2 (en) 2010-08-23 2014-07-15 Syntrix Biosystems, Inc. Aminopyridine- and aminopyrimidinecarboxamides as CXCR2 modulators
JP5937102B2 (ja) * 2010-12-14 2016-06-22 エレクトロフォレティクス リミテッド カゼインキナーゼ１デルタ（ｃｋ１デルタ）阻害剤
JPWO2014132919A1 (ja) * 2013-02-28 2017-02-02 国立大学法人京都大学 診断用組成物
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WO2015112048A1 (en) * 2014-01-24 2015-07-30 Huawei Technologies Co., Ltd. Method and device for cross-polarization interference suppression
CN104059028B (zh) * 2014-06-06 2020-10-16 北京智博高科生物技术有限公司 与Aβ斑块具有亲和力的含手性侧链取代的氟代2-芳基苯并杂环化合物、其制备方法及应用
KR101709731B1 (ko) * 2015-05-22 2017-02-23 한국과학기술연구원 벤조옥사졸 또는 벤조티아졸 화합물, 그의 제조, 및 용도
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US10478513B2 (en) * 2015-08-18 2019-11-19 The Regents Of The University Of Califonia Nitroxide containing amyloid binding agents for imaging and therapeutic uses
KR101812424B1 (ko) * 2016-12-28 2017-12-27 충북대학교 산학협력단 2-(2-아미노-5-(1-(피퍼리딘-4-일)-1H-피라졸-3-일)피리딘-3-일)벤조[d]옥사졸-6-올 및 이를 유효성분으로 포함하는 치매의 예방 및 치료용 조성물
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Also Published As

Publication number Publication date
CL2007001784A1 (es) 2008-01-18
US7670591B2 (en) 2010-03-02
ZA200810163B (en) 2010-05-26
WO2007149030A1 (en) 2007-12-27
CN101506201A (zh) 2009-08-12
JP5548842B2 (ja) 2014-07-16
AU2007261786A1 (en) 2007-12-27
CN101506201B (zh) 2012-03-14
MX2008015718A (es) 2008-12-19
KR20090021224A (ko) 2009-02-27
WO2007149030A8 (en) 2008-02-28
US20080027051A1 (en) 2008-01-31
UY30419A1 (es) 2008-01-31
JP2009541309A (ja) 2009-11-26
AR061515A1 (es) 2008-09-03
IL195669A0 (en) 2009-09-01
EP2035418A1 (en) 2009-03-18
TW200813035A (en) 2008-03-16
CA2655084A1 (en) 2007-12-27

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