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NO20083695L - Meridamycin analoger for behandlingen av neurodegenererende sykdommer - Google Patents

Meridamycin analoger for behandlingen av neurodegenererende sykdommer

Info

Publication number
NO20083695L
NO20083695L NO20083695A NO20083695A NO20083695L NO 20083695 L NO20083695 L NO 20083695L NO 20083695 A NO20083695 A NO 20083695A NO 20083695 A NO20083695 A NO 20083695A NO 20083695 L NO20083695 L NO 20083695L
Authority
NO
Norway
Prior art keywords
treatment
neurodegenerative diseases
meridamycin
analogues
meridamycin analogues
Prior art date
Application number
NO20083695A
Other languages
English (en)
Inventor
Kevin Pong
Edmund Idris Graziani
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of NO20083695L publication Critical patent/NO20083695L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Det beskrives en forbindelse med strukturen vist nedenfor. Denne forbindelse og dens anvendelse for fremstilling av medikamenter anvendelige ved behandlingen av neurodegenerative forstyrrelser, er beskrevet.
NO20083695A 2006-03-07 2008-08-27 Meridamycin analoger for behandlingen av neurodegenererende sykdommer NO20083695L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77994006P 2006-03-07 2006-03-07
PCT/US2007/005645 WO2007103347A1 (en) 2006-03-07 2007-03-05 Meridamycin analogues for the treatment of neurodegenerative disorders

Publications (1)

Publication Number Publication Date
NO20083695L true NO20083695L (no) 2008-10-03

Family

ID=38289934

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20083695A NO20083695L (no) 2006-03-07 2008-08-27 Meridamycin analoger for behandlingen av neurodegenererende sykdommer

Country Status (19)

Country Link
US (1) US7745457B2 (no)
EP (1) EP1991551A1 (no)
JP (1) JP2009529049A (no)
KR (1) KR20080099317A (no)
CN (1) CN101426796A (no)
AR (1) AR059738A1 (no)
AU (1) AU2007223962A1 (no)
BR (1) BRPI0708611A2 (no)
CA (1) CA2643350A1 (no)
CR (1) CR10272A (no)
EC (1) ECSP088718A (no)
IL (1) IL193414A0 (no)
MX (1) MX2008011312A (no)
NO (1) NO20083695L (no)
PE (1) PE20081550A1 (no)
RU (1) RU2008132779A (no)
TW (1) TW200804400A (no)
WO (1) WO2007103347A1 (no)
ZA (1) ZA200807678B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR052269A1 (es) * 2004-12-20 2007-03-07 Wyeth Corp Analogos de rapamicina, un proceso para su elaboracion y los usos de los mismos en la preparacion de un medicamento para el tratamiento de trastornos neurologicos, proliferativos e inflamatorios.
RU2007119585A (ru) * 2004-12-20 2009-01-27 Вайет (Us) Производные рапамицина и их применение при лечении неврологических заболеваний

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9302016D0 (en) 1993-02-02 1993-03-17 Sandoz Ltd Compounds
GB9318144D0 (en) 1993-09-01 1993-10-20 Sandoz Ltd Organic compounds
JP4105761B2 (ja) * 1993-11-19 2008-06-25 アボット・ラボラトリーズ ラパミシン（マクロライド）の半合成類似体免疫調節剤
GT200500035A (es) * 2004-03-02 2005-10-24 Macrolidos y metodos para producir los mismos
AU2005219389A1 (en) 2004-03-02 2005-09-15 Wyeth Non-immunosuppressive immunophilin ligands as neuroprotective and/or neuroregenerative agents
BRPI0511777A (pt) * 2004-06-03 2008-01-15 Wyeth Corp complexo de meridamicina sintase, célula hospedeira, policetìdeo sintase sintética, seqüência de ácido nucleico, vetor recombinante, ácido nucleico isolado, construção de ácido nucleico quimérico, métodos para produzir um composto de policetìdeo e para determinar o requerimento estrutural da atividade de policetìdio, análogo de meridamicina, cepa de streptomyces mutante, ceto meridamicina c36 ou um sal farmaceuticamente aceitável da mesma, composto de desoximeridamicina, sais ou misturas farmaceuticamente aceitável do mesmo, composição farmacêutica, uso de um composto, cepa de actinomiceto m507, e, métodos para produzir um macrolìdeo e para produzir um composto
US7595187B2 (en) 2004-11-12 2009-09-29 Wyeth Elaiophylin biosynthetic gene cluster
AR052269A1 (es) 2004-12-20 2007-03-07 Wyeth Corp Analogos de rapamicina, un proceso para su elaboracion y los usos de los mismos en la preparacion de un medicamento para el tratamiento de trastornos neurologicos, proliferativos e inflamatorios.
RU2007119585A (ru) 2004-12-20 2009-01-27 Вайет (Us) Производные рапамицина и их применение при лечении неврологических заболеваний

Also Published As

Publication number Publication date
AR059738A1 (es) 2008-04-23
CR10272A (es) 2008-10-03
ECSP088718A (es) 2008-10-31
PE20081550A1 (es) 2008-12-31
JP2009529049A (ja) 2009-08-13
MX2008011312A (es) 2008-09-12
WO2007103347A1 (en) 2007-09-13
TW200804400A (en) 2008-01-16
CN101426796A (zh) 2009-05-06
BRPI0708611A2 (pt) 2011-06-07
KR20080099317A (ko) 2008-11-12
US7745457B2 (en) 2010-06-29
IL193414A0 (en) 2009-05-04
EP1991551A1 (en) 2008-11-19
RU2008132779A (ru) 2010-04-20
CA2643350A1 (en) 2007-09-13
ZA200807678B (en) 2009-08-26
AU2007223962A1 (en) 2007-09-13
US20070213525A1 (en) 2007-09-13

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