NO20082837L - Isotopmerkede benzotiazolforbindelser som avbildningsmidler for amyloidogene proteiner - Google Patents
Isotopmerkede benzotiazolforbindelser som avbildningsmidler for amyloidogene proteinerInfo
- Publication number
- NO20082837L NO20082837L NO20082837A NO20082837A NO20082837L NO 20082837 L NO20082837 L NO 20082837L NO 20082837 A NO20082837 A NO 20082837A NO 20082837 A NO20082837 A NO 20082837A NO 20082837 L NO20082837 L NO 20082837L
- Authority
- NO
- Norway
- Prior art keywords
- isotope
- imaging agents
- benzothiazole compounds
- amyloidogenic proteins
- labeled
- Prior art date
Links
- 102000009091 Amyloidogenic Proteins Human genes 0.000 title 1
- 108010048112 Amyloidogenic Proteins Proteins 0.000 title 1
- IOJUPLGTWVMSFF-UHFFFAOYSA-N benzothiazole Chemical class C1=CC=C2SC=NC2=C1 IOJUPLGTWVMSFF-UHFFFAOYSA-N 0.000 title 1
- 239000012216 imaging agent Substances 0.000 title 1
- 239000012535 impurity Substances 0.000 abstract 1
- TYZROVQLWOKYKF-ZDUSSCGKSA-N linezolid Chemical compound O=C1O[C@@H](CNC(=O)C)CN1C(C=C1F)=CC=C1N1CCOCC1 TYZROVQLWOKYKF-ZDUSSCGKSA-N 0.000 abstract 1
- 229960003907 linezolid Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
- C07D277/66—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Psychiatry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74106705P | 2005-12-01 | 2005-12-01 | |
| PCT/US2006/045807 WO2007064773A2 (fr) | 2005-12-01 | 2006-11-30 | Composes de benzothiazole marques aux isotopes utiles en tant qu'agents d'imagerie pour des proteines amyloidogeniques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20082837L true NO20082837L (no) | 2008-08-28 |
Family
ID=37981903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20082837A NO20082837L (no) | 2005-12-01 | 2008-06-26 | Isotopmerkede benzotiazolforbindelser som avbildningsmidler for amyloidogene proteiner |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20090142269A1 (fr) |
| EP (1) | EP1971584A2 (fr) |
| JP (1) | JP2009519239A (fr) |
| CN (1) | CN101351458A (fr) |
| AU (1) | AU2006320556A1 (fr) |
| BR (1) | BRPI0619251A2 (fr) |
| CA (1) | CA2631905A1 (fr) |
| NO (1) | NO20082837L (fr) |
| RU (1) | RU2008126463A (fr) |
| WO (1) | WO2007064773A2 (fr) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101355940B (zh) * | 2005-09-16 | 2013-03-27 | 匹兹堡大学高等教育联邦体系 | 用于检测具有至少一种促淀粉样变蛋白的淀粉样沉积物的体内或体外方法 |
| FR2916762B1 (fr) * | 2007-05-31 | 2013-11-15 | Biomerieux Sa | Nouveaux substrats enzymatiques de nitroreductase |
| CN103450077B (zh) | 2007-06-08 | 2016-07-06 | 满康德股份有限公司 | IRE-1α抑制剂 |
| CN101790387B (zh) * | 2007-08-30 | 2013-03-20 | 通用电气健康护理有限公司 | 放射性药物组合物 |
| WO2010036905A1 (fr) * | 2008-09-26 | 2010-04-01 | Eisai R & D Management Co., Ltd. | Composés benzoxazole et procédés d'utilisation |
| WO2010036908A1 (fr) * | 2008-09-26 | 2010-04-01 | Eisai R & D Management Co., Ltd. | Utilisation de composés benzoxazole dans le traitement du paludisme |
| GB0821994D0 (en) * | 2008-12-02 | 2009-01-07 | Ge Healthcare Ltd | In viva imaging method |
| KR101123178B1 (ko) * | 2009-04-09 | 2012-06-13 | (주)에스메디 | 2-아릴벤조싸이오펜 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 퇴행성 뇌질환의 진단 또는 치료용 약학적 조성물 |
| WO2011100396A2 (fr) * | 2010-02-10 | 2011-08-18 | Trustees Of Boston University | Taux sériques de clustérine en présence d'une cardiomyopathie accompagnée d'une amyloïdose systémique |
| CN102558091B (zh) * | 2011-12-22 | 2014-10-08 | 合肥工业大学 | 一种苯并噻唑类衍生物及其用途 |
| CA2894994C (fr) | 2012-12-21 | 2019-11-12 | National Institute Of Radiological Sciences | Composes d'imagerie des proteines tau qui s'accumulent dans le cerveau |
| CN102977051B (zh) * | 2012-12-24 | 2015-06-10 | 湖南大学 | 一种合成2-取代苯并噻唑衍生物的方法 |
| JP2016079108A (ja) * | 2014-10-10 | 2016-05-16 | 国立大学法人京都大学 | 放射性ヨウ素標識スチリル置換芳香族ヘテロ環化合物 |
| GB201617339D0 (en) | 2016-10-12 | 2016-11-23 | Lytix Biopharma As | Therapeutic compounds |
| JP7293343B2 (ja) | 2018-05-09 | 2023-06-19 | アプリノイア セラピューティクス リミテッド | ヘテロアリール化合物及びその使用 |
| JP2022506749A (ja) | 2018-11-02 | 2022-01-17 | ファウント バイオ， インコーポレイテッド | 架橋される材料 |
| BR112021020951A2 (pt) * | 2019-04-19 | 2021-12-14 | Fount Bio Inc | Dispensação e retenção de agentes ativos dentro da pele |
| KR20220100921A (ko) | 2019-11-13 | 2022-07-18 | 아프리노이아 테라퓨틱스 리미티드 | 타우 단백질 응집체를 분해하기 위한 화합물 및 이의 용도 |
| CN111925343B (zh) * | 2020-08-12 | 2021-11-23 | 石家庄四药有限公司 | 一种利奈唑胺降解杂质的合成方法 |
| WO2022159436A1 (fr) * | 2021-01-19 | 2022-07-28 | Cold Spring Harbor Laboratory | Inhibiteurs de dyrk et de pim |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4666829A (en) * | 1985-05-15 | 1987-05-19 | University Of California | Polypeptide marker for Alzheimer's disease and its use for diagnosis |
| US5231000A (en) * | 1987-10-08 | 1993-07-27 | The Mclean Hospital | Antibodies to A4 amyloid peptide |
| US6168776B1 (en) * | 1994-07-19 | 2001-01-02 | University Of Pittsburgh | Alkyl, alkenyl and alkynyl Chrysamine G derivatives for the antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition |
| US6001331A (en) * | 1996-01-24 | 1999-12-14 | Warner-Lambert Company | Method of imaging amyloid deposits |
| HU230581B1 (hu) * | 2000-08-24 | 2017-01-30 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Tioflavin-származékok és alkalmazásuk az Alzheimer-kór diagnózisában és kezelésében |
| AU2003212490A1 (en) * | 2002-02-13 | 2003-09-04 | Amersham Plc | Benzothiazole derivatives for in vivo imaging of amyloid plaques |
| CA2438032C (fr) * | 2003-03-14 | 2013-05-07 | University Of Pittsburgh | Derives de benzothiazole et compositions et utilisations connexes |
-
2006
- 2006-11-30 EP EP06844660A patent/EP1971584A2/fr not_active Withdrawn
- 2006-11-30 BR BRPI0619251A patent/BRPI0619251A2/pt not_active IP Right Cessation
- 2006-11-30 US US12/095,760 patent/US20090142269A1/en not_active Abandoned
- 2006-11-30 JP JP2008543445A patent/JP2009519239A/ja active Pending
- 2006-11-30 RU RU2008126463/04A patent/RU2008126463A/ru not_active Application Discontinuation
- 2006-11-30 CA CA002631905A patent/CA2631905A1/fr not_active Abandoned
- 2006-11-30 WO PCT/US2006/045807 patent/WO2007064773A2/fr not_active Ceased
- 2006-11-30 CN CNA2006800502158A patent/CN101351458A/zh active Pending
- 2006-11-30 AU AU2006320556A patent/AU2006320556A1/en not_active Abandoned
-
2008
- 2008-06-26 NO NO20082837A patent/NO20082837L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1971584A2 (fr) | 2008-09-24 |
| RU2008126463A (ru) | 2010-01-10 |
| JP2009519239A (ja) | 2009-05-14 |
| AU2006320556A8 (en) | 2008-07-31 |
| AU2006320556A1 (en) | 2007-06-07 |
| BRPI0619251A2 (pt) | 2016-09-06 |
| CA2631905A1 (fr) | 2007-06-07 |
| WO2007064773A3 (fr) | 2007-11-15 |
| US20090142269A1 (en) | 2009-06-04 |
| WO2007064773A2 (fr) | 2007-06-07 |
| CN101351458A (zh) | 2009-01-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |