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NO20081328L - Modifiserte antigen-bindende molekyler med endret celle-signaliseringsaktivitet - Google Patents

Modifiserte antigen-bindende molekyler med endret celle-signaliseringsaktivitet

Info

Publication number
NO20081328L
NO20081328L NO20081328A NO20081328A NO20081328L NO 20081328 L NO20081328 L NO 20081328L NO 20081328 A NO20081328 A NO 20081328A NO 20081328 A NO20081328 A NO 20081328A NO 20081328 L NO20081328 L NO 20081328L
Authority
NO
Norway
Prior art keywords
modified
relates
abms
present
cell signaling
Prior art date
Application number
NO20081328A
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English (en)
Other versions
NO345919B1 (no
Inventor
Pablo Umaña
Ekkehard Mössner
Original Assignee
Glycart Biotechnology Ag
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37865318&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20081328(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glycart Biotechnology Ag filed Critical Glycart Biotechnology Ag
Publication of NO20081328L publication Critical patent/NO20081328L/no
Publication of NO345919B1 publication Critical patent/NO345919B1/no

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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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Abstract

SAMMENDRAG Foreliggende oppfinnelse angår modifiserte antigen-bindende molekyler (ABM'er). I spesielle utførelsesformer angår foreliggende oppfinnelse rekombinante monoklonale antistoffer eller fragmenter, omfattende kimære, primatiserte eller humaniserte antistoffer eller fragmenter, som har endret evne til å mediere cellesignalerings aktivitet ved et mål-antigen, og/eller endret evne til å mediere kryssbinding av ett eller flere mål-antigener. I tillegg angår foreliggende oppfinnelse nukleinsyremolekyler som koder for slike modfiserte ABM'er og vektorer og vertsceller omfattende slike nukleinsyremolekyler. Oppfinnelsen angår videre fremgangsmåter for fremstilling av de modifiserte ABM'ene ifølge oppfinnelsen, og fremgangsmåter for anvendelse av disse modifiserte ABM'ene ved behandling av sykdom. I tillegg angår foreliggende oppfinnelse modifiserte ABM'er med modifisert glykosylering som har forbedrede terapeutiske egenskaper, omfattende antistoffer med økt Fc-reseptorbinding og økt effektorfunksjon.
NO20081328A 2005-08-26 2006-08-25 Modifiserte antigen-bindende molekyler med endret celle-signaliseringsaktivitet NO345919B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71145405P 2005-08-26 2005-08-26
PCT/IB2006/003294 WO2007031875A2 (en) 2005-08-26 2006-08-25 Modified antigen binding molecules with altered cell signaling activity

Publications (2)

Publication Number Publication Date
NO20081328L true NO20081328L (no) 2008-05-23
NO345919B1 NO345919B1 (no) 2021-10-18

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ID=37865318

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20081328A NO345919B1 (no) 2005-08-26 2006-08-25 Modifiserte antigen-bindende molekyler med endret celle-signaliseringsaktivitet
NO20210557A NO20210557A1 (no) 2005-08-26 2021-05-04 Modifiserte antigen-bindende molekyler med endret celle-signaliseringsaktivitet

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NO20210557A NO20210557A1 (no) 2005-08-26 2021-05-04 Modifiserte antigen-bindende molekyler med endret celle-signaliseringsaktivitet

Country Status (18)

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US (2) US20070071745A1 (no)
EP (3) EP2395024B1 (no)
JP (3) JP5373396B2 (no)
KR (2) KR101460932B1 (no)
CN (2) CN103204935B (no)
AR (1) AR055137A1 (no)
AU (1) AU2006290433B2 (no)
BR (2) BR122020020335B1 (no)
CA (1) CA2619298C (no)
CL (2) CL2010000822A1 (no)
IL (1) IL189756A (no)
NO (2) NO345919B1 (no)
PH (1) PH12012502376B1 (no)
RU (2) RU2482132C2 (no)
SG (1) SG192479A1 (no)
TW (2) TWI615407B (no)
WO (1) WO2007031875A2 (no)
ZA (1) ZA200802500B (no)

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