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NO20081264L - Krystallinske former av {(1R),2S]-2-Aminopropionsyre 2-[4-(4-Fluor-2-Metyl-1H-Indol-5-Yloksy)-5-Metylpyrrolo[2,1-F][1,2,4]Triazin-6-Yloksy]-1-Metyletylester - Google Patents

Krystallinske former av {(1R),2S]-2-Aminopropionsyre 2-[4-(4-Fluor-2-Metyl-1H-Indol-5-Yloksy)-5-Metylpyrrolo[2,1-F][1,2,4]Triazin-6-Yloksy]-1-Metyletylester

Info

Publication number
NO20081264L
NO20081264L NO20081264A NO20081264A NO20081264L NO 20081264 L NO20081264 L NO 20081264L NO 20081264 A NO20081264 A NO 20081264A NO 20081264 A NO20081264 A NO 20081264A NO 20081264 L NO20081264 L NO 20081264L
Authority
NO
Norway
Prior art keywords
yloxy
methylpyrrolo
indol
triazine
fluoro
Prior art date
Application number
NO20081264A
Other languages
English (en)
Norwegian (no)
Inventor
John E Thornton
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NO20081264L publication Critical patent/NO20081264L/no

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
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  • Physical Education & Sports Medicine (AREA)
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  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • AIDS & HIV (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
NO20081264A 2005-09-27 2008-03-11 Krystallinske former av {(1R),2S]-2-Aminopropionsyre 2-[4-(4-Fluor-2-Metyl-1H-Indol-5-Yloksy)-5-Metylpyrrolo[2,1-F][1,2,4]Triazin-6-Yloksy]-1-Metyletylester NO20081264L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72102105P 2005-09-27 2005-09-27
PCT/US2006/037777 WO2007038648A1 (fr) 2005-09-27 2006-09-26 Formes cristallines de l'acide [(1r), 2s]-2-aminopropionique 2-[4-(4-fluoro-2-methyl-1h-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy]-1-methylethyle ester

Publications (1)

Publication Number Publication Date
NO20081264L true NO20081264L (no) 2008-06-20

Family

ID=37692626

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20081264A NO20081264L (no) 2005-09-27 2008-03-11 Krystallinske former av {(1R),2S]-2-Aminopropionsyre 2-[4-(4-Fluor-2-Metyl-1H-Indol-5-Yloksy)-5-Metylpyrrolo[2,1-F][1,2,4]Triazin-6-Yloksy]-1-Metyletylester

Country Status (6)

Country Link
US (2) US20070088035A1 (fr)
EP (1) EP1928880A1 (fr)
JP (1) JP2009511440A (fr)
CN (1) CN101291934B (fr)
NO (1) NO20081264L (fr)
WO (1) WO2007038648A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2010538T3 (da) * 2006-04-21 2013-03-18 Bristol Myers Squibb Co Fremgangsmåde til fremstilling af [(1R), 2S]-2-aminopropionsyre 2-[4-(4-fluor-2-methyl-1H-indol-5-yloxy)-5-methylpyrrol]2,1-f-[1,2,4-triazin-6-yloxy]-1-methylethylester
ES2539620T3 (es) 2008-12-19 2015-07-02 Cephalon, Inc. Pirrolotriazina como inhibidor de ALK y de JAK2
EP2663283B1 (fr) * 2011-01-14 2017-05-10 Bristol-Myers Squibb Company Comprimé contenant une charge élevée de brivanib alaninate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6982265B1 (en) * 1999-05-21 2006-01-03 Bristol Myers Squibb Company Pyrrolotriazine inhibitors of kinases
TWI329112B (en) * 2002-07-19 2010-08-21 Bristol Myers Squibb Co Novel inhibitors of kinases
WO2006030947A1 (fr) * 2004-09-13 2006-03-23 Eisai R & D Management Co., Ltd. Utilisation conjointe d’un compose a base de sulfonamide et d'un inhibiteur d’angiogenese
US20060257400A1 (en) * 2005-05-13 2006-11-16 Bristol-Myers Squibb Company Combination therapy
DK2010538T3 (da) * 2006-04-21 2013-03-18 Bristol Myers Squibb Co Fremgangsmåde til fremstilling af [(1R), 2S]-2-aminopropionsyre 2-[4-(4-fluor-2-methyl-1H-indol-5-yloxy)-5-methylpyrrol]2,1-f-[1,2,4-triazin-6-yloxy]-1-methylethylester

Also Published As

Publication number Publication date
US7932383B2 (en) 2011-04-26
WO2007038648A1 (fr) 2007-04-05
US20090247531A1 (en) 2009-10-01
US20070088035A1 (en) 2007-04-19
JP2009511440A (ja) 2009-03-19
CN101291934B (zh) 2012-06-27
CN101291934A (zh) 2008-10-22
EP1928880A1 (fr) 2008-06-11

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